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The map label for this gene is fusA [H]

Identifier: 238921445

GI number: 238921445

Start: 3484627

End: 3486735

Strand: Reverse

Name: fusA [H]

Synonym: NT01EI_3597

Alternate gene names: 238921445

Gene position: 3486735-3484627 (Counterclockwise)

Preceding gene: 238921446

Following gene: 238921444

Centisome position: 91.46

GC content: 54.05

Gene sequence:

>2109_bases
ATGGCTCGTACAACACCCATTTCGCGTTACCGTAACATCGGTATCAGCGCTCACATCGACGCCGGTAAGACCACTACTAC
CGAACGTATCCTGTTCTACACCGGTGTAAACCATAAGATCGGTGAAGTTCATGATGGTGCTGCCACCATGGACTGGATGG
AGCAGGAGCAGGAGCGTGGTATCACCATTACCTCCGCTGCGACCACCGCTTTCTGGTCTGGCATGGCCAAACAGTTTGAG
CCGCACCGTATCAACATCATCGATACCCCGGGGCACGTTGACTTCACCATCGAAGTAGAACGTTCCATGCGTGTACTGGA
TGGTGCGGTCATGGTTTACTGCGCCGTTGGTGGTGTTCAGCCGCAGTCTGAAACCGTATGGCGTCAGGCCAACAAGTATC
ATGTTCCGCGCATCGCGTTCGTTAACAAAATGGACCGCATGGGTGCGAACTTCCTGAAAGTTGTTAACCAGATCAAAACC
CGCCTGGGCGCTAACCCGGTTCCGTTGCAGTTGGCAATCGGTGCTGAAGAAGCATTCACCGGTATCGTTGACCTGGTTAA
AATGAAAGCCATCAACTGGAACGAAGCCGATCAGGGCGTGACCTTCACCTATGAAGACATCCCGGCTGACATGGTTGAAC
TGGCTAACGAATGGCACCAGTTCCTGGTTGAGTCCGCAGCCGAAGCGTCTGAAGAGCTGATGGACAAGTACCTGGGCGGT
GAAACGCTGTCTGAAGAAGAGATCAAAAATGCTCTGCGTCAGCGCGTACTGAACAACGAAATCATCCTGGTTACCTGTGG
CTCCGCGTTCAAGAACAAGGGCGTACAGGCAATGCTGGATGCAGTCATTGAGTACCTGCCGTCACCGACCGATGTTCCGG
CGATCAAAGGTATCCTGGACGACGGTAAAGATACCCCGGCTGAGCGTCACTCTGACGACAACGAGCCGTTCGCGGCGCTG
GCGTTCAAAATCGCCACCGACCCGTTCGTGGGTAACCTGACCTTCTTCCGCGTATACTCCGGTGTGGTTAACTCTGGTGA
TACCGTACTGAACTCCGTGAAGTCTGCACGTGAGCGTTTCGGCCGTATCGTTCAGATGCACGCCAACAAGCGTGAAGAGA
TCAAAGAAGTTCGCGCGGGTGACATCGCCGCGGCAATCGGTCTGAAGGACGTCACCACCGGTGATACCCTGTGTGACCAG
AACGCGCCGATCATCCTGGAGCGTATGGAATTCCCTGAGCCGGTAATCTCCATCGCCGTTGAGCCGAAAACCAAGGCTGA
CCAGGAGAAAATGGGCCTGGCACTGGGCCGTCTGGCTAAGGAAGACCCGTCTTTCCGCGTACGTACTGACGAAGAATCCA
ACCAGACCATCATCTCCGGCATGGGTGAATTGCACCTGGAAATCATCGTTGACCGTATGAAGCGCGAGTTCAACGTTGAA
GCCAACGTCGGTAAACCGCAGGTTGCTTACCGTGAAACCATCCGTGACACCGTCAAGGATGTTGAAGGTAAACACGCCAA
ACAGTCCGGTGGTCGCGGTCAGTACGGTCATGTCGTTATCGACATGTTCCCGTTGGAGCCGGGTGGCGAAGGCTACACCT
TCACCAACGACATCAAGGGCGGTGTGATTCCGGGTGAATACATCCCGGCAGTTGACAAGGGTATCCAAGAGCAGCTGAAG
TCCGGTCCGATGGCCGGTTATCCGGTAGTAGACCTGGGCGTACGTCTGCACTTTGGTTCTTACCATGACGTTGACTCCTC
TGAACTGGCGTTTAAACTGGCTGCCTCTCTCGCGTTTAAAGAAGCCTTCAAACGCGCTAAGCCGGTTCTGCTTGAGCCGA
TCATGAAGGTTGAAGTAGAAACTCCGGAAGATTACATGGGTGACGTTATCGGTGACTTGAACCGTCGTCGCGGCATGATC
GAAGGTATGGAAGATACTGCGACTGGCAAGACTGTTCGTGCGCAGGTTCCGTTGTCTGAAATGTTTGGTTATGCTACTGA
CCTGCGTTCCCAGACCCAGGGCCGTGCTTCATACTCCATGGAGTTCCTGAAGTATGCTGAAGCACCGACTAACGTCGCTC
AGGCCGTTATTGAAGCACGTGGCAAATAA

Upstream 100 bases:

>100_bases
GGTAATATCATCGGTATGTTAGTCACCAAGCGGGCGCTTAAGCTTAAGTCGCCCGCTTTGGGTAACTTAACTTGAACGCC
CTAGGATATAGAGGAATCAA

Downstream 100 bases:

>100_bases
GCCTCTGCTTTAACATATTGATCCCGCGCCCTCTCCTTCGGTGAGGGCGCAAGATAAGGAATATAACCGTGTCTAAAGAA
AAATTTGAACGTTCAAAACC

Product: hypothetical protein

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MARTTPISRYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQFE
PHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYHVPRIAFVNKMDRMGANFLKVVNQIKT
RLGANPVPLQLAIGAEEAFTGIVDLVKMKAINWNEADQGVTFTYEDIPADMVELANEWHQFLVESAAEASEELMDKYLGG
ETLSEEEIKNALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIEYLPSPTDVPAIKGILDDGKDTPAERHSDDNEPFAAL
AFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKSARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDQ
NAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVRTDEESNQTIISGMGELHLEIIVDRMKREFNVE
ANVGKPQVAYRETIRDTVKDVEGKHAKQSGGRGQYGHVVIDMFPLEPGGEGYTFTNDIKGGVIPGEYIPAVDKGIQEQLK
SGPMAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASLAFKEAFKRAKPVLLEPIMKVEVETPEDYMGDVIGDLNRRRGMI
EGMEDTATGKTVRAQVPLSEMFGYATDLRSQTQGRASYSMEFLKYAEAPTNVAQAVIEARGK

Sequences:

>Translated_702_residues
MARTTPISRYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQFE
PHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYHVPRIAFVNKMDRMGANFLKVVNQIKT
RLGANPVPLQLAIGAEEAFTGIVDLVKMKAINWNEADQGVTFTYEDIPADMVELANEWHQFLVESAAEASEELMDKYLGG
ETLSEEEIKNALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIEYLPSPTDVPAIKGILDDGKDTPAERHSDDNEPFAAL
AFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKSARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDQ
NAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVRTDEESNQTIISGMGELHLEIIVDRMKREFNVE
ANVGKPQVAYRETIRDTVKDVEGKHAKQSGGRGQYGHVVIDMFPLEPGGEGYTFTNDIKGGVIPGEYIPAVDKGIQEQLK
SGPMAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASLAFKEAFKRAKPVLLEPIMKVEVETPEDYMGDVIGDLNRRRGMI
EGMEDTATGKTVRAQVPLSEMFGYATDLRSQTQGRASYSMEFLKYAEAPTNVAQAVIEARGK
>Mature_701_residues
ARTTPISRYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQFEP
HRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYHVPRIAFVNKMDRMGANFLKVVNQIKTR
LGANPVPLQLAIGAEEAFTGIVDLVKMKAINWNEADQGVTFTYEDIPADMVELANEWHQFLVESAAEASEELMDKYLGGE
TLSEEEIKNALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIEYLPSPTDVPAIKGILDDGKDTPAERHSDDNEPFAALA
FKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKSARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDQN
APIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVRTDEESNQTIISGMGELHLEIIVDRMKREFNVEA
NVGKPQVAYRETIRDTVKDVEGKHAKQSGGRGQYGHVVIDMFPLEPGGEGYTFTNDIKGGVIPGEYIPAVDKGIQEQLKS
GPMAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASLAFKEAFKRAKPVLLEPIMKVEVETPEDYMGDVIGDLNRRRGMIE
GMEDTATGKTVRAQVPLSEMFGYATDLRSQTQGRASYSMEFLKYAEAPTNVAQAVIEARGK

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=704, Percent_Identity=45.0284090909091, Blast_Score=576, Evalue=1e-164,
Organism=Homo sapiens, GI19923640, Length=718, Percent_Identity=37.883008356546, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI25306287, Length=694, Percent_Identity=37.1757925072046, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI25306283, Length=457, Percent_Identity=39.6061269146608, Blast_Score=302, Evalue=8e-82,
Organism=Homo sapiens, GI4503483, Length=469, Percent_Identity=27.7185501066098, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI157426893, Length=154, Percent_Identity=35.7142857142857, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI94966754, Length=137, Percent_Identity=39.4160583941606, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI310132016, Length=120, Percent_Identity=40, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI310110807, Length=120, Percent_Identity=40, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI310123363, Length=120, Percent_Identity=40, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI94966752, Length=68, Percent_Identity=45.5882352941176, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789738, Length=704, Percent_Identity=90.7670454545455, Blast_Score=1325, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=497, Percent_Identity=25.9557344064386, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI48994988, Length=182, Percent_Identity=37.9120879120879, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788922, Length=155, Percent_Identity=35.4838709677419, Blast_Score=90, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17533571, Length=705, Percent_Identity=43.8297872340426, Blast_Score=543, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI17556745, Length=711, Percent_Identity=30.098452883263, Blast_Score=299, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI17506493, Length=505, Percent_Identity=27.3267326732673, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17557151, Length=192, Percent_Identity=34.375, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988819, Length=148, Percent_Identity=34.4594594594595, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988811, Length=147, Percent_Identity=35.3741496598639, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323098, Length=700, Percent_Identity=42.2857142857143, Blast_Score=563, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6322359, Length=801, Percent_Identity=30.3370786516854, Blast_Score=367, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6324707, Length=475, Percent_Identity=27.1578947368421, Blast_Score=104, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320593, Length=475, Percent_Identity=27.1578947368421, Blast_Score=104, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6323320, Length=153, Percent_Identity=33.9869281045752, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324166, Length=176, Percent_Identity=34.6590909090909, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582462, Length=706, Percent_Identity=44.4759206798867, Blast_Score=584, Evalue=1e-167,
Organism=Drosophila melanogaster, GI221458488, Length=740, Percent_Identity=31.6216216216216, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24585709, Length=812, Percent_Identity=27.0935960591133, Blast_Score=172, Evalue=9e-43,
Organism=Drosophila melanogaster, GI24585711, Length=812, Percent_Identity=27.0935960591133, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24585713, Length=812, Percent_Identity=27.0935960591133, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI78706572, Length=186, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28574573, Length=141, Percent_Identity=37.5886524822695, Blast_Score=83, Evalue=6e-16,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 77473; Mature: 77342

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTTPISRYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
CCCCCCHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTAFWSGMAKQFEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQ
EEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHEEEEECCCCC
PQSETVWRQANKYHVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEAFT
CCHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHH
GIVDLVKMKAINWNEADQGVTFTYEDIPADMVELANEWHQFLVESAAEASEELMDKYLGG
HHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETLSEEEIKNALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIEYLPSPTDVPAIKGILD
CCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHC
DGKDTPAERHSDDNEPFAALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKSARERF
CCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDQNAPIILERMEFPEPVISIAV
HHHHHHHCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEE
EPKTKADQEKMGLALGRLAKEDPSFRVRTDEESNQTIISGMGELHLEIIVDRMKREFNVE
CCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
ANVGKPQVAYRETIRDTVKDVEGKHAKQSGGRGQYGHVVIDMFPLEPGGEGYTFTNDIKG
CCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEEECCCCCCCCEEECCCCC
GVIPGEYIPAVDKGIQEQLKSGPMAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASLAFK
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECEEEEECCCCCCCHHHHHHHHHHHHHHH
EAFKRAKPVLLEPIMKVEVETPEDYMGDVIGDLNRRRGMIEGMEDTATGKTVRAQVPLSE
HHHHHCCCHHHCCHHEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHH
MFGYATDLRSQTQGRASYSMEFLKYAEAPTNVAQAVIEARGK
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ARTTPISRYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
CCCCCHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTAFWSGMAKQFEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQ
EEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHEEEEECCCCC
PQSETVWRQANKYHVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEAFT
CCHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHH
GIVDLVKMKAINWNEADQGVTFTYEDIPADMVELANEWHQFLVESAAEASEELMDKYLGG
HHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETLSEEEIKNALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIEYLPSPTDVPAIKGILD
CCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHC
DGKDTPAERHSDDNEPFAALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKSARERF
CCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDQNAPIILERMEFPEPVISIAV
HHHHHHHCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEE
EPKTKADQEKMGLALGRLAKEDPSFRVRTDEESNQTIISGMGELHLEIIVDRMKREFNVE
CCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
ANVGKPQVAYRETIRDTVKDVEGKHAKQSGGRGQYGHVVIDMFPLEPGGEGYTFTNDIKG
CCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEEECCCCCCCCEEECCCCC
GVIPGEYIPAVDKGIQEQLKSGPMAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASLAFK
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECEEEEECCCCCCCHHHHHHHHHHHHHHH
EAFKRAKPVLLEPIMKVEVETPEDYMGDVIGDLNRRRGMIEGMEDTATGKTVRAQVPLSE
HHHHHCCCHHHCCHHEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHH
MFGYATDLRSQTQGRASYSMEFLKYAEAPTNVAQAVIEARGK
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA