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The map label for this gene is yjcE [H]

Identifier: 238921373

GI number: 238921373

Start: 3409059

End: 3410705

Strand: Reverse

Name: yjcE [H]

Synonym: NT01EI_3517

Alternate gene names: 238921373

Gene position: 3410705-3409059 (Counterclockwise)

Preceding gene: 238921374

Following gene: 238921372

Centisome position: 89.47

GC content: 59.99

Gene sequence:

>1647_bases
ATGGAAATATTCTTCACAATCCTGATCCTGATTTTGGTGGTATCGCTCTCCGGCGTGGTAACGCGCCTGCTACCGTTTCA
AATCCCGCTGCCGCTGATGCAGATCGCCATCGGGGCGCTGTTGGCCTGGCCCCACTTTGGACTGCATGTGGATTTTGACC
CTGAGCTGTTCCTGGTATTGTTTATTCCGCCGCTGCTGTTTGCTGACGGTTGGAAAACCCCGACGCGGGAGTTTTTGTAC
CACGGCAGGGAGATCCTGGGGCTGGCACTGGTATTGGTGCTGATCACCGTGGCTGGCGTCGGCTACTTTCTGCATCTGTT
GCTGCCGGAGGTGCCGCTGGTGGCGGCCTTTGCGCTGGCTGCCGTGTTGTCGCCCACCGATGCCGTGGCGCTTGGTGGTA
TCGTTGGCCAGGGGAGGATACCTAAAAGCATCATGGGGGTGCTGGAAGGGGAGGCGCTGATGAACGATGCCTCCGGCCTG
GTTTCCCTGAAGTTCGCTATCGCGGTGGCGATGGGCACCATGGTGTTTACCGTCTCCGGTGCGACGTTGGAGTTTCTGAA
AGTGGCGTTGGGCGGTCTGCTGACCGGCGCGGCGGTCACCTGGCTGTACAGCAAGTCCCTGCGGATGATGAGCCGCTGGG
CGGGAGATGATCCGGCGACCCAGATCGTCCTTCTGATGCTGTTGCCGTTCGCCAGCTATCTGATCGCAGAGCATGTTGGC
GTTTCCGGTATTCTGGCGGCGGTGGCGGCGGGGATGACTATCAGCCAGTCCGGAGTGATCCGCAATGCGCCGCTGACGAT
GCGCCTGCGTGCCAACAGCGTGTGGGCGATGCTGGAATTTGTGTTTAACGGCATGGTGTTTATCATGCTGGGCCTACAGC
TGCCGGGGATCCTGGAGAACTCGATTATTCAGGCCGACCTCGACCCCAATATCGAAACCTGGTATCTGTTCGCCGACGTG
GTGCTGGTGTATGCGCTGCTGCTGGTATTGCGTTTCCTGTGGCTGTGGGGGATGAAACGTATCAGCCTGCGCTTCTTTAA
GCACAACCCGCTGCAGTTTGCCTCCTACGGCATACGCGATCTGTGGATTGCTTCGTTTGCCGGGGTCCGTGGGGCCATCA
CGCTGGCCGGTGTGCTCTCCATTCCCCTGTTCCTGACCGACGGTACGCCGTTCCCCGGTCGCTATCAGCTGGTGTTTCTG
GCCGCCGGAGTGATCCTGTTTTCCCTGCTGGTGGGAGTGGTGGCGCTGCCGCTGCTGCTGCGCGGTGTCGAGATCACCGA
TAGCGTGGCCTACCGAGAGGAGGAGCTGATGGCGAAGTCGGTCAGCGCCGAGGTGGCCATTGAGAGCCTGAAGAAGATGC
AGGAGCGCCTTGAGGCTGATACCGAGGAGAACATCGATCCACAACTGCTGACCGAAGTCAGCTCGCGGGTTATAGGCAGT
CTCAGGCGGCGGGTGATGACCAAGGAGAACGCCGACGAAATCCGTGAGGTGGAGAATCTGGAGCGCCGTTTTCGCCTGAC
GGCGCTGCGCGCTGAACGCGGCGAGCTGTACCACCTGCGTGCCACCCAGAAGATCAGTAACGAGACGCTGCAGAAGATGC
TGCACGATCTGGATCTGCTGGAGGCGCTGCTGGTCGAAAAAAGCTAA

Upstream 100 bases:

>100_bases
TCTCTGCTCCTTAGGGTAGATTTCTCTTCGGCTCAAAATTCATAAGATGATATTTTGTAAAGCGTTGCGTTAGCCCTGTT
GGCGTTGAGTCTGAAAGAAC

Downstream 100 bases:

>100_bases
GGGTTAGCGTTGAGCTTTTCCGCCCCGGAGGCCGTGCTTCCGGGGCTAATGAGATGGTCACCCCCACCCTGTGAGCGGTA
CGCTGGCAGGGTGTTTTTCT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MEIFFTILILILVVSLSGVVTRLLPFQIPLPLMQIAIGALLAWPHFGLHVDFDPELFLVLFIPPLLFADGWKTPTREFLY
HGREILGLALVLVLITVAGVGYFLHLLLPEVPLVAAFALAAVLSPTDAVALGGIVGQGRIPKSIMGVLEGEALMNDASGL
VSLKFAIAVAMGTMVFTVSGATLEFLKVALGGLLTGAAVTWLYSKSLRMMSRWAGDDPATQIVLLMLLPFASYLIAEHVG
VSGILAAVAAGMTISQSGVIRNAPLTMRLRANSVWAMLEFVFNGMVFIMLGLQLPGILENSIIQADLDPNIETWYLFADV
VLVYALLLVLRFLWLWGMKRISLRFFKHNPLQFASYGIRDLWIASFAGVRGAITLAGVLSIPLFLTDGTPFPGRYQLVFL
AAGVILFSLLVGVVALPLLLRGVEITDSVAYREEELMAKSVSAEVAIESLKKMQERLEADTEENIDPQLLTEVSSRVIGS
LRRRVMTKENADEIREVENLERRFRLTALRAERGELYHLRATQKISNETLQKMLHDLDLLEALLVEKS

Sequences:

>Translated_548_residues
MEIFFTILILILVVSLSGVVTRLLPFQIPLPLMQIAIGALLAWPHFGLHVDFDPELFLVLFIPPLLFADGWKTPTREFLY
HGREILGLALVLVLITVAGVGYFLHLLLPEVPLVAAFALAAVLSPTDAVALGGIVGQGRIPKSIMGVLEGEALMNDASGL
VSLKFAIAVAMGTMVFTVSGATLEFLKVALGGLLTGAAVTWLYSKSLRMMSRWAGDDPATQIVLLMLLPFASYLIAEHVG
VSGILAAVAAGMTISQSGVIRNAPLTMRLRANSVWAMLEFVFNGMVFIMLGLQLPGILENSIIQADLDPNIETWYLFADV
VLVYALLLVLRFLWLWGMKRISLRFFKHNPLQFASYGIRDLWIASFAGVRGAITLAGVLSIPLFLTDGTPFPGRYQLVFL
AAGVILFSLLVGVVALPLLLRGVEITDSVAYREEELMAKSVSAEVAIESLKKMQERLEADTEENIDPQLLTEVSSRVIGS
LRRRVMTKENADEIREVENLERRFRLTALRAERGELYHLRATQKISNETLQKMLHDLDLLEALLVEKS
>Mature_548_residues
MEIFFTILILILVVSLSGVVTRLLPFQIPLPLMQIAIGALLAWPHFGLHVDFDPELFLVLFIPPLLFADGWKTPTREFLY
HGREILGLALVLVLITVAGVGYFLHLLLPEVPLVAAFALAAVLSPTDAVALGGIVGQGRIPKSIMGVLEGEALMNDASGL
VSLKFAIAVAMGTMVFTVSGATLEFLKVALGGLLTGAAVTWLYSKSLRMMSRWAGDDPATQIVLLMLLPFASYLIAEHVG
VSGILAAVAAGMTISQSGVIRNAPLTMRLRANSVWAMLEFVFNGMVFIMLGLQLPGILENSIIQADLDPNIETWYLFADV
VLVYALLLVLRFLWLWGMKRISLRFFKHNPLQFASYGIRDLWIASFAGVRGAITLAGVLSIPLFLTDGTPFPGRYQLVFL
AAGVILFSLLVGVVALPLLLRGVEITDSVAYREEELMAKSVSAEVAIESLKKMQERLEADTEENIDPQLLTEVSSRVIGS
LRRRVMTKENADEIREVENLERRFRLTALRAERGELYHLRATQKISNETLQKMLHDLDLLEALLVEKS

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=484, Percent_Identity=23.7603305785124, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI15529998, Length=442, Percent_Identity=25.7918552036199, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI41872703, Length=541, Percent_Identity=23.8447319778189, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI27734935, Length=288, Percent_Identity=23.2638888888889, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI14211919, Length=261, Percent_Identity=22.9885057471264, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1790501, Length=548, Percent_Identity=73.1751824817518, Blast_Score=809, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980847, Length=415, Percent_Identity=22.8915662650602, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25150332, Length=473, Percent_Identity=21.7758985200846, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71999817, Length=575, Percent_Identity=22.9565217391304, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71999819, Length=575, Percent_Identity=22.9565217391304, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71999821, Length=518, Percent_Identity=22.972972972973, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71992101, Length=252, Percent_Identity=21.8253968253968, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71992107, Length=252, Percent_Identity=21.8253968253968, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=370, Percent_Identity=24.0540540540541, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281364513, Length=482, Percent_Identity=23.0290456431535, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221473222, Length=483, Percent_Identity=23.3954451345756, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI221473215, Length=489, Percent_Identity=23.1083844580777, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221473212, Length=501, Percent_Identity=22.5548902195609, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221510738, Length=382, Percent_Identity=23.8219895287958, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221510734, Length=382, Percent_Identity=23.8219895287958, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 60263; Mature: 60263

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFFTILILILVVSLSGVVTRLLPFQIPLPLMQIAIGALLAWPHFGLHVDFDPELFLVL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHH
FIPPLLFADGWKTPTREFLYHGREILGLALVLVLITVAGVGYFLHLLLPEVPLVAAFALA
HHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AVLSPTDAVALGGIVGQGRIPKSIMGVLEGEALMNDASGLVSLKFAIAVAMGTMVFTVSG
HHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECC
ATLEFLKVALGGLLTGAAVTWLYSKSLRMMSRWAGDDPATQIVLLMLLPFASYLIAEHVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
VSGILAAVAAGMTISQSGVIRNAPLTMRLRANSVWAMLEFVFNGMVFIMLGLQLPGILEN
HHHHHHHHHHCCEECCCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
SIIQADLDPNIETWYLFADVVLVYALLLVLRFLWLWGMKRISLRFFKHNPLQFASYGIRD
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHCCHHH
LWIASFAGVRGAITLAGVLSIPLFLTDGTPFPGRYQLVFLAAGVILFSLLVGVVALPLLL
HHHHHHHCCHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVEITDSVAYREEELMAKSVSAEVAIESLKKMQERLEADTEENIDPQLLTEVSSRVIGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LRRRVMTKENADEIREVENLERRFRLTALRAERGELYHLRATQKISNETLQKMLHDLDLL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
EALLVEKS
HHHHHCCC
>Mature Secondary Structure
MEIFFTILILILVVSLSGVVTRLLPFQIPLPLMQIAIGALLAWPHFGLHVDFDPELFLVL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHH
FIPPLLFADGWKTPTREFLYHGREILGLALVLVLITVAGVGYFLHLLLPEVPLVAAFALA
HHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AVLSPTDAVALGGIVGQGRIPKSIMGVLEGEALMNDASGLVSLKFAIAVAMGTMVFTVSG
HHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECC
ATLEFLKVALGGLLTGAAVTWLYSKSLRMMSRWAGDDPATQIVLLMLLPFASYLIAEHVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
VSGILAAVAAGMTISQSGVIRNAPLTMRLRANSVWAMLEFVFNGMVFIMLGLQLPGILEN
HHHHHHHHHHCCEECCCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
SIIQADLDPNIETWYLFADVVLVYALLLVLRFLWLWGMKRISLRFFKHNPLQFASYGIRD
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHCCHHH
LWIASFAGVRGAITLAGVLSIPLFLTDGTPFPGRYQLVFLAAGVILFSLLVGVVALPLLL
HHHHHHHCCHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVEITDSVAYREEELMAKSVSAEVAIESLKKMQERLEADTEENIDPQLLTEVSSRVIGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LRRRVMTKENADEIREVENLERRFRLTALRAERGELYHLRATQKISNETLQKMLHDLDLL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
EALLVEKS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]