Click here to switch to the map view.

The map label for this gene is glpA [H]

Identifier: 238921322

GI number: 238921322

Start: 3359209

End: 3360858

Strand: Reverse

Name: glpA [H]

Synonym: NT01EI_3466

Alternate gene names: 238921322

Gene position: 3360858-3359209 (Counterclockwise)

Preceding gene: 238921326

Following gene: 238921321

Centisome position: 88.16

GC content: 63.33

Gene sequence:

>1650_bases
ATGTTACAGAGCCCCGCATCACAGGAAACTGATGTCGTCATTATCGGCGGCGGCGCCACCGGCGCCGGTATCGCCCGTGA
CTGCGCGCGCCGTGGCCTGCGTTGCATTCTGCTGGAGCGCCACGACATCGCCACCGGCGCGACCGGCCGTAATCATGGTT
TGCTGCACAGCGGTGCCCGTTACGCGGTGACCGACGACGAGTCTGCGCGCGAATGTATTGAAGAAAACCGTATTCTGAAG
CGCATCGCCCGCCACTGCGTCGAGCGTACCGACGGGCTGTTCATTACGCTGCCGGAAGATGATCTGGCCTATCAGCCGCG
TTTTATTGCGTCCTGCCGCGCCGCGGGTATCGATGCCGAAGCCATCGATCCGGCCGAGGCGCTGCGCCTGGAGCCTGCCG
CCAACCCGAATCTGCTGGGCGCGGTGCGCGTGCCGGATGGTACTGTCGATCCTTTCCGCCTGACGGCGGCCAACATGCTG
GATGCGCGTGAGCACGGCGCCCAGGCGCTGACCTATCATGAGGTGTGCGGGCTGCTGCGCCAGGGCGATCGGGTGAACGG
TGTGCGCGTTATCGACCATAAATCGCGCCAGCGCTATGACATTCACGCACAGATTGTGGTCAACGCTGCCGGGATCTGGG
GGCAGCACATCGCCGAGTATGCCGATCTGCGTATCAAGATGTTCCCAGCCAAGGGGGCGCTGCTGATCCTGGGGCACCGT
ATCAACAACATGGTGATCAACCGCTGCCGCAAGCCGGCGGATGCCGATATTCTGGTGCCGGGCGATACCATTTCACTGAT
CGGTACCACCTCGACCCACGTCGATTACGATCAGATAGACAACATGATGGTCACGCCGCAGGAGGTGGATACCCTGATCC
GCGAAGGGGAGAAGCTGGCACCCAAGCTGGCGGCGACCCGCATTCTGCGGGCCTACGCCGGAGTGCGTCCGCTGGTGGCC
AGCGATGACGATCCGAGCGGGCGTAACGTCAGCCGCGGTATCGTGCTGCTGGATCACGCGGTGCGCGATGGGCTGGAGGG
CTTTATCACCATTACCGGCGGTAAGCTGATGACCTATCGCCTGATGGCCGAATGGGCCACTGATAAAGTCTGTGAAAAGC
TGGGCGTCACCACCCTCTGCACCACCGCCAGCGAGCCGCTGCCCGGCTCCGGTCAGTCGGCCGAAGAGACGCTGCGCAAG
GTGGTTTCGCTGCCGGCGCCGATCCGTGGCTCGGCGGTTTACCGCCATGGCGATCGCGCCGATCGCCTGCTGAACGGCGA
TCGCCTGAACAGCAGCCTGGTGTGTGAATGTGAAGCGGTGACTGCCGGGGAAGTCCGCTACGCCGTGGACTCCCTGACGG
TGAATAACCTGGTGGATCTGCGCCGTCGCACCCGCGTGGGGATGGGCACCTGTCAGGGCGAGCTGTGCGCCTGCCGTGCG
GCCGGATTGCTGAACCGATTTAAGGTCACCACGCCGCAGCAGTCTATCGATCAGCTGTCCCACTTCCTGAACGAACGCTG
GAAGGGGATCCGTCCGATCGCCTGGGGTAATGCACTGCGCGAAAGCGAATTTACCAGTTGGGTTTACCAGGGGCTGTGCG
GGATGGATACCGCGCTGCCGCAGCGCGGGGAGAGCGACGATGAAATTTGA

Upstream 100 bases:

>100_bases
TGGTTTCGTTTTGTGCGCGTATTTGCTCCTTATCAAACATTTTATCGCCGTAATATGGCTTACTAGGTTCATTACTACTC
ATTTGGCTTGGGAGCCACTC

Downstream 100 bases:

>100_bases
TACCCTGATGATCGGCGGAGGGCTGGCCGGACTGGCCTGTGGCATTCGTCTGGCGGAGGCCGGGCAGCGCTGTGCTATCG
TCAGCGCCGGGCAGAGTGCG

Product: sn-glycerol-3-phosphate dehydrogenase subunit A

Products: NA

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MLQSPASQETDVVIIGGGATGAGIARDCARRGLRCILLERHDIATGATGRNHGLLHSGARYAVTDDESARECIEENRILK
RIARHCVERTDGLFITLPEDDLAYQPRFIASCRAAGIDAEAIDPAEALRLEPAANPNLLGAVRVPDGTVDPFRLTAANML
DAREHGAQALTYHEVCGLLRQGDRVNGVRVIDHKSRQRYDIHAQIVVNAAGIWGQHIAEYADLRIKMFPAKGALLILGHR
INNMVINRCRKPADADILVPGDTISLIGTTSTHVDYDQIDNMMVTPQEVDTLIREGEKLAPKLAATRILRAYAGVRPLVA
SDDDPSGRNVSRGIVLLDHAVRDGLEGFITITGGKLMTYRLMAEWATDKVCEKLGVTTLCTTASEPLPGSGQSAEETLRK
VVSLPAPIRGSAVYRHGDRADRLLNGDRLNSSLVCECEAVTAGEVRYAVDSLTVNNLVDLRRRTRVGMGTCQGELCACRA
AGLLNRFKVTTPQQSIDQLSHFLNERWKGIRPIAWGNALRESEFTSWVYQGLCGMDTALPQRGESDDEI

Sequences:

>Translated_549_residues
MLQSPASQETDVVIIGGGATGAGIARDCARRGLRCILLERHDIATGATGRNHGLLHSGARYAVTDDESARECIEENRILK
RIARHCVERTDGLFITLPEDDLAYQPRFIASCRAAGIDAEAIDPAEALRLEPAANPNLLGAVRVPDGTVDPFRLTAANML
DAREHGAQALTYHEVCGLLRQGDRVNGVRVIDHKSRQRYDIHAQIVVNAAGIWGQHIAEYADLRIKMFPAKGALLILGHR
INNMVINRCRKPADADILVPGDTISLIGTTSTHVDYDQIDNMMVTPQEVDTLIREGEKLAPKLAATRILRAYAGVRPLVA
SDDDPSGRNVSRGIVLLDHAVRDGLEGFITITGGKLMTYRLMAEWATDKVCEKLGVTTLCTTASEPLPGSGQSAEETLRK
VVSLPAPIRGSAVYRHGDRADRLLNGDRLNSSLVCECEAVTAGEVRYAVDSLTVNNLVDLRRRTRVGMGTCQGELCACRA
AGLLNRFKVTTPQQSIDQLSHFLNERWKGIRPIAWGNALRESEFTSWVYQGLCGMDTALPQRGESDDEI
>Mature_549_residues
MLQSPASQETDVVIIGGGATGAGIARDCARRGLRCILLERHDIATGATGRNHGLLHSGARYAVTDDESARECIEENRILK
RIARHCVERTDGLFITLPEDDLAYQPRFIASCRAAGIDAEAIDPAEALRLEPAANPNLLGAVRVPDGTVDPFRLTAANML
DAREHGAQALTYHEVCGLLRQGDRVNGVRVIDHKSRQRYDIHAQIVVNAAGIWGQHIAEYADLRIKMFPAKGALLILGHR
INNMVINRCRKPADADILVPGDTISLIGTTSTHVDYDQIDNMMVTPQEVDTLIREGEKLAPKLAATRILRAYAGVRPLVA
SDDDPSGRNVSRGIVLLDHAVRDGLEGFITITGGKLMTYRLMAEWATDKVCEKLGVTTLCTTASEPLPGSGQSAEETLRK
VVSLPAPIRGSAVYRHGDRADRLLNGDRLNSSLVCECEAVTAGEVRYAVDSLTVNNLVDLRRRTRVGMGTCQGELCACRA
AGLLNRFKVTTPQQSIDQLSHFLNERWKGIRPIAWGNALRESEFTSWVYQGLCGMDTALPQRGESDDEI

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=390, Percent_Identity=27.9487179487179, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI285002231, Length=390, Percent_Identity=27.9487179487179, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI197927446, Length=293, Percent_Identity=25.5972696245734, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI21361378, Length=293, Percent_Identity=25.5972696245734, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1788574, Length=535, Percent_Identity=77.196261682243, Blast_Score=815, Evalue=0.0,
Organism=Escherichia coli, GI2367226, Length=462, Percent_Identity=24.025974025974, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17509253, Length=416, Percent_Identity=29.5673076923077, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI115534726, Length=507, Percent_Identity=25.8382642998028, Blast_Score=102, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6322036, Length=487, Percent_Identity=27.3100616016427, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161077125, Length=395, Percent_Identity=29.3670886075949, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24653942, Length=395, Percent_Identity=29.3670886075949, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24653944, Length=395, Percent_Identity=29.3670886075949, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20130025, Length=395, Percent_Identity=29.3670886075949, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20130091, Length=244, Percent_Identity=31.1475409836066, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24586295, Length=387, Percent_Identity=24.2894056847545, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR006076
- InterPro:   IPR017752
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO; PF04324 Fer2_BFD [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 59904; Mature: 59904

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQSPASQETDVVIIGGGATGAGIARDCARRGLRCILLERHDIATGATGRNHGLLHSGAR
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEECCCE
YAVTDDESARECIEENRILKRIARHCVERTDGLFITLPEDDLAYQPRFIASCRAAGIDAE
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCC
AIDPAEALRLEPAANPNLLGAVRVPDGTVDPFRLTAANMLDAREHGAQALTYHEVCGLLR
CCCHHHHHEECCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHH
QGDRVNGVRVIDHKSRQRYDIHAQIVVNAAGIWGQHIAEYADLRIKMFPAKGALLILGHR
CCCCCCCEEEEECCCCCCEEEEEEEEEEECCHHHHHHHHHHCCEEEEECCCCEEEEEECH
INNMVINRCRKPADADILVPGDTISLIGTTSTHVDYDQIDNMMVTPQEVDTLIREGEKLA
HHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHHCCEEECHHHHHHHHHCCHHHH
PKLAATRILRAYAGVRPLVASDDDPSGRNVSRGIVLLDHAVRDGLEGFITITGGKLMTYR
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEHHHHHCCCCEEEEEECCCEEEHH
LMAEWATDKVCEKLGVTTLCTTASEPLPGSGQSAEETLRKVVSLPAPIRGSAVYRHGDRA
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCHH
DRLLNGDRLNSSLVCECEAVTAGEVRYAVDSLTVNNLVDLRRRTRVGMGTCQGELCACRA
HHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AGLLNRFKVTTPQQSIDQLSHFLNERWKGIRPIAWGNALRESEFTSWVYQGLCGMDTALP
HHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCC
QRGESDDEI
CCCCCCCCC
>Mature Secondary Structure
MLQSPASQETDVVIIGGGATGAGIARDCARRGLRCILLERHDIATGATGRNHGLLHSGAR
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEECCCE
YAVTDDESARECIEENRILKRIARHCVERTDGLFITLPEDDLAYQPRFIASCRAAGIDAE
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCC
AIDPAEALRLEPAANPNLLGAVRVPDGTVDPFRLTAANMLDAREHGAQALTYHEVCGLLR
CCCHHHHHEECCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHH
QGDRVNGVRVIDHKSRQRYDIHAQIVVNAAGIWGQHIAEYADLRIKMFPAKGALLILGHR
CCCCCCCEEEEECCCCCCEEEEEEEEEEECCHHHHHHHHHHCCEEEEECCCCEEEEEECH
INNMVINRCRKPADADILVPGDTISLIGTTSTHVDYDQIDNMMVTPQEVDTLIREGEKLA
HHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHHCCEEECHHHHHHHHHCCHHHH
PKLAATRILRAYAGVRPLVASDDDPSGRNVSRGIVLLDHAVRDGLEGFITITGGKLMTYR
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEHHHHHCCCCEEEEEECCCEEEHH
LMAEWATDKVCEKLGVTTLCTTASEPLPGSGQSAEETLRKVVSLPAPIRGSAVYRHGDRA
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCHH
DRLLNGDRLNSSLVCECEAVTAGEVRYAVDSLTVNNLVDLRRRTRVGMGTCQGELCACRA
HHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AGLLNRFKVTTPQQSIDQLSHFLNERWKGIRPIAWGNALRESEFTSWVYQGLCGMDTALP
HHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCC
QRGESDDEI
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]