Click here to switch to the map view.

The map label for this gene is uidA [H]

Identifier: 238921288

GI number: 238921288

Start: 3316877

End: 3318694

Strand: Reverse

Name: uidA [H]

Synonym: NT01EI_3431

Alternate gene names: 238921288

Gene position: 3318694-3316877 (Counterclockwise)

Preceding gene: 238921294

Following gene: 238921287

Centisome position: 87.05

GC content: 62.05

Gene sequence:

>1818_bases
ATGTTAAAGCCGATTGAAAGCCGTTCCCGTGAGCGTAAGAACCTGAGCGGGCTGTGGCAGTTTGTACCGGACGTTCAGCG
CTGTGGTCACCGTGAACAGTGGTGGTGCGGGACGCTGCCGGGGGGGCGCACCATCGCGGTTCCGGGCAGTTTTAACGACC
AGTTTGCCGACGCGGCGATCCGTAACCACGTAGGCGACGTGTGGTATCAGACCGAGGTGCGCGTGCCGCGCGGCTGGAAC
GGGCAGCGGATCGTGCTGCGCTTTGACGCGGTAACCCATGGAGCGACAGTGTGGGTGGATGAGACCCAGGTGATGGTGCA
TCAGGGGGGATATACCCCTTTTGAGGCGGACATCAGCGCCCTGCTGGCCGGGCGTGAGCAGGTGCGTGTCACCGTCTGCG
TCAATAACGAGCTCTCCTGGCACACCATCCCGCCGGGGCGGGTCACCGAGGTCAACGGTGAGCGTCGCCTGCAGTATAGC
TATGATTTCTTTAACTATGCCGGGATACATCGCCCGGTGTGGCTCTATTCGACGCCACAGGATTATCTCCGTGATGTCCG
CGTGACGACCGAAATCAGCGCCGATGGGGCGCAGGGATTGGTGCACTATGCGGTTGATGCCGGTGATGTCGGCGTGCATT
GCCGCCTGCTGGATGACCAGCAGCACTGTGTGGCCGAGAGCGAGGGAGACGAGGGGACGCTGACGGTCTCCAACCCACGG
CTATGGCAGCCGGGGGAGGGCTATCTGTATACCCTGATGGTCTACAGCGGCGAGGGCGACGGGGCCGATGAATACGCCCT
ACGGGTGGGGATCCGTACCGTAGAGGTGACGGAAACTGCCTTCCTGATCAATGGCAATCCATTCTATTTTACCGGTTTTG
GCCGTCATGAGGATGCGGATCTGCGCGGCAGGGGGCTGGATCATGTGCTGCTGGTGCACGATCACGCCCTGATGCGCTGG
ATCGGCGCCAACTCGTATCGCACCTCTCACTACCCCTATGCCGAGGAGATGTTGGACTGGGCCGATGAGCACGGCATCGT
GGTGATCGATGAGACGCCGGCCGTGGGGATGATGGCCCTGCACGGCTTCACGCTGGATCTGACCTCCCGGGGGGAGAAAC
TGTTCTGCGAGGAGCGCATCGGCTCCCAGACCCAGCAGGCCCATCTGCAGGCGATCCGCGAGCTTATCGCCCGTGATAAA
AACCACCCCAGCGTGGTGATGTGGAGCCTGGCGAACGAACCCGATGTCCGCGAGGCGGCAGCGCGCGACTACTTCGCTCC
CCTGGTGCAGGCGGCACGGGAGCTGGACCCCTCCCGCCCGCTGTGCTGCGTCAACATTATGCTCTGCCCGCCGGACAAGG
ACACCATCAGCGATCTGTTTGACGTGCTGTGTCTGAACCGTTACTTCGGCTGGTATGTCAACAGCGGCGATCTGGCTACC
GCCGGGCGTGAGCTGGAGCAGGAGCTGTCGGTATGGCATGAGCGGCACCGCAAGCCGATCATCATTACGGAATACGGGGC
CGATACCCTGGCCGGACTGCACAGTCTGTATCCGGAGATGTGGAGCGAGGAGTTTCAGGCACAGTTTTTAACCACCTATC
ACCGGGTATTTGACCGTCTGCCCTACGTGGTGGGGGAGCAGGTGTGGAACTTCGCCGACTTTGCCACGGCGCAGGGGATC
CTGCGCGCCGGTGGCAACAGGAAAGGGGTATTTACCCGCGACAGAAAGCCCAAGGCGGCGGCTTTTACCCTCAAGGCGCG
CTGGACGGCGGTGCAATACGGTATGAAACCCGCGGGTGACAAAGGGGGAGCGCAATGA

Upstream 100 bases:

>100_bases
GCTGCCGACATAAAACTTCCGCCGATCTTAAGGTAACTTTTTCCGCCTCCTACGGGTGTAGAGATGATCCCTGATTTTTC
TCTCACTCTGGAGTGTCGCC

Downstream 100 bases:

>100_bases
GTCAGTCACTGAGCTGGAGGGCGGTGATTGGCTATGGCTGTGGCGATATGGCCAATAACTTTGCCTTTGCCATGGGGGCG
CTGTTTCTGCTGAGCTATTA

Product: beta-D-glucuronidase

Products: NA

Alternate protein names: GUS; Beta-D-glucuronoside glucuronosohydrolase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MLKPIESRSRERKNLSGLWQFVPDVQRCGHREQWWCGTLPGGRTIAVPGSFNDQFADAAIRNHVGDVWYQTEVRVPRGWN
GQRIVLRFDAVTHGATVWVDETQVMVHQGGYTPFEADISALLAGREQVRVTVCVNNELSWHTIPPGRVTEVNGERRLQYS
YDFFNYAGIHRPVWLYSTPQDYLRDVRVTTEISADGAQGLVHYAVDAGDVGVHCRLLDDQQHCVAESEGDEGTLTVSNPR
LWQPGEGYLYTLMVYSGEGDGADEYALRVGIRTVEVTETAFLINGNPFYFTGFGRHEDADLRGRGLDHVLLVHDHALMRW
IGANSYRTSHYPYAEEMLDWADEHGIVVIDETPAVGMMALHGFTLDLTSRGEKLFCEERIGSQTQQAHLQAIRELIARDK
NHPSVVMWSLANEPDVREAAARDYFAPLVQAARELDPSRPLCCVNIMLCPPDKDTISDLFDVLCLNRYFGWYVNSGDLAT
AGRELEQELSVWHERHRKPIIITEYGADTLAGLHSLYPEMWSEEFQAQFLTTYHRVFDRLPYVVGEQVWNFADFATAQGI
LRAGGNRKGVFTRDRKPKAAAFTLKARWTAVQYGMKPAGDKGGAQ

Sequences:

>Translated_605_residues
MLKPIESRSRERKNLSGLWQFVPDVQRCGHREQWWCGTLPGGRTIAVPGSFNDQFADAAIRNHVGDVWYQTEVRVPRGWN
GQRIVLRFDAVTHGATVWVDETQVMVHQGGYTPFEADISALLAGREQVRVTVCVNNELSWHTIPPGRVTEVNGERRLQYS
YDFFNYAGIHRPVWLYSTPQDYLRDVRVTTEISADGAQGLVHYAVDAGDVGVHCRLLDDQQHCVAESEGDEGTLTVSNPR
LWQPGEGYLYTLMVYSGEGDGADEYALRVGIRTVEVTETAFLINGNPFYFTGFGRHEDADLRGRGLDHVLLVHDHALMRW
IGANSYRTSHYPYAEEMLDWADEHGIVVIDETPAVGMMALHGFTLDLTSRGEKLFCEERIGSQTQQAHLQAIRELIARDK
NHPSVVMWSLANEPDVREAAARDYFAPLVQAARELDPSRPLCCVNIMLCPPDKDTISDLFDVLCLNRYFGWYVNSGDLAT
AGRELEQELSVWHERHRKPIIITEYGADTLAGLHSLYPEMWSEEFQAQFLTTYHRVFDRLPYVVGEQVWNFADFATAQGI
LRAGGNRKGVFTRDRKPKAAAFTLKARWTAVQYGMKPAGDKGGAQ
>Mature_605_residues
MLKPIESRSRERKNLSGLWQFVPDVQRCGHREQWWCGTLPGGRTIAVPGSFNDQFADAAIRNHVGDVWYQTEVRVPRGWN
GQRIVLRFDAVTHGATVWVDETQVMVHQGGYTPFEADISALLAGREQVRVTVCVNNELSWHTIPPGRVTEVNGERRLQYS
YDFFNYAGIHRPVWLYSTPQDYLRDVRVTTEISADGAQGLVHYAVDAGDVGVHCRLLDDQQHCVAESEGDEGTLTVSNPR
LWQPGEGYLYTLMVYSGEGDGADEYALRVGIRTVEVTETAFLINGNPFYFTGFGRHEDADLRGRGLDHVLLVHDHALMRW
IGANSYRTSHYPYAEEMLDWADEHGIVVIDETPAVGMMALHGFTLDLTSRGEKLFCEERIGSQTQQAHLQAIRELIARDK
NHPSVVMWSLANEPDVREAAARDYFAPLVQAARELDPSRPLCCVNIMLCPPDKDTISDLFDVLCLNRYFGWYVNSGDLAT
AGRELEQELSVWHERHRKPIIITEYGADTLAGLHSLYPEMWSEEFQAQFLTTYHRVFDRLPYVVGEQVWNFADFATAQGI
LRAGGNRKGVFTRDRKPKAAAFTLKARWTAVQYGMKPAGDKGGAQ

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=621, Percent_Identity=43.1561996779388, Blast_Score=463, Evalue=1e-130,
Organism=Escherichia coli, GI1787903, Length=607, Percent_Identity=63.4266886326194, Blast_Score=798, Evalue=0.0,
Organism=Escherichia coli, GI48994920, Length=512, Percent_Identity=23.6328125, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786539, Length=475, Percent_Identity=26.3157894736842, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17510825, Length=620, Percent_Identity=36.7741935483871, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI62471735, Length=624, Percent_Identity=42.3076923076923, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI19922582, Length=624, Percent_Identity=42.3076923076923, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24655438, Length=624, Percent_Identity=42.3076923076923, Blast_Score=472, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24651745, Length=633, Percent_Identity=41.2322274881517, Blast_Score=430, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.31 [H]

Molecular weight: Translated: 68355; Mature: 68355

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00719 GLYCOSYL_HYDROL_F2_1 ; PS00608 GLYCOSYL_HYDROL_F2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPIESRSRERKNLSGLWQFVPDVQRCGHREQWWCGTLPGGRTIAVPGSFNDQFADAAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCHHHHHHHH
RNHVGDVWYQTEVRVPRGWNGQRIVLRFDAVTHGATVWVDETQVMVHQGGYTPFEADISA
HHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEEECCEEEEECCCCCCHHHHHHH
LLAGREQVRVTVCVNNELSWHTIPPGRVTEVNGERRLQYSYDFFNYAGIHRPVWLYSTPQ
HHCCCCEEEEEEEECCCCEEEECCCCCEEECCCCEEEEEEECCHHHCCCCCCEEEECCCH
DYLRDVRVTTEISADGAQGLVHYAVDAGDVGVHCRLLDDQQHCVAESEGDEGTLTVSNPR
HHHHHCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCHHHHCCCCCCCCEEEECCCC
LWQPGEGYLYTLMVYSGEGDGADEYALRVGIRTVEVTETAFLINGNPFYFTGFGRHEDAD
CCCCCCCEEEEEEEEECCCCCCCCEEEEEEEEEEEEEEEEEEEECCEEEEECCCCCCCCC
LRGRGLDHVLLVHDHALMRWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETPAVGMMAL
CCCCCCCEEEEEECHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEE
HGFTLDLTSRGEKLFCEERIGSQTQQAHLQAIRELIARDKNHPSVVMWSLANEPDVREAA
ECEEEEECCCCCEEEEHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHH
ARDYFAPLVQAARELDPSRPLCCVNIMLCPPDKDTISDLFDVLCLNRYFGWYVNSGDLAT
HHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCEEECCCCHHH
AGRELEQELSVWHERHRKPIIITEYGADTLAGLHSLYPEMWSEEFQAQFLTTYHRVFDRL
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PYVVGEQVWNFADFATAQGILRAGGNRKGVFTRDRKPKAAAFTLKARWTAVQYGMKPAGD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEEEEEEEEEEECCCCCCCC
KGGAQ
CCCCC
>Mature Secondary Structure
MLKPIESRSRERKNLSGLWQFVPDVQRCGHREQWWCGTLPGGRTIAVPGSFNDQFADAAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCHHHHHHHH
RNHVGDVWYQTEVRVPRGWNGQRIVLRFDAVTHGATVWVDETQVMVHQGGYTPFEADISA
HHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEEECCEEEEECCCCCCHHHHHHH
LLAGREQVRVTVCVNNELSWHTIPPGRVTEVNGERRLQYSYDFFNYAGIHRPVWLYSTPQ
HHCCCCEEEEEEEECCCCEEEECCCCCEEECCCCEEEEEEECCHHHCCCCCCEEEECCCH
DYLRDVRVTTEISADGAQGLVHYAVDAGDVGVHCRLLDDQQHCVAESEGDEGTLTVSNPR
HHHHHCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCHHHHCCCCCCCCEEEECCCC
LWQPGEGYLYTLMVYSGEGDGADEYALRVGIRTVEVTETAFLINGNPFYFTGFGRHEDAD
CCCCCCCEEEEEEEEECCCCCCCCEEEEEEEEEEEEEEEEEEEECCEEEEECCCCCCCCC
LRGRGLDHVLLVHDHALMRWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETPAVGMMAL
CCCCCCCEEEEEECHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEE
HGFTLDLTSRGEKLFCEERIGSQTQQAHLQAIRELIARDKNHPSVVMWSLANEPDVREAA
ECEEEEECCCCCEEEEHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHH
ARDYFAPLVQAARELDPSRPLCCVNIMLCPPDKDTISDLFDVLCLNRYFGWYVNSGDLAT
HHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCEEECCCCHHH
AGRELEQELSVWHERHRKPIIITEYGADTLAGLHSLYPEMWSEEFQAQFLTTYHRVFDRL
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PYVVGEQVWNFADFATAQGILRAGGNRKGVFTRDRKPKAAAFTLKARWTAVQYGMKPAGD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEEEEEEEEEEECCCCCCCC
KGGAQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534890; 8125312; 2103475; 9097039; 9278503 [H]