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The map label for this gene is rpiA

Identifier: 238921219

GI number: 238921219

Start: 3248503

End: 3249162

Strand: Reverse

Name: rpiA

Synonym: NT01EI_3362

Alternate gene names: 238921219

Gene position: 3249162-3248503 (Counterclockwise)

Preceding gene: 238921221

Following gene: 238921218

Centisome position: 85.23

GC content: 60.15

Gene sequence:

>660_bases
ATGACGCAGGATGAATTGAAAAAAGCAGTGGGCTGGGCAGCGCTGAAGTATGTGCGCCCTGGGACCATTGTCGGGGTAGG
CACCGGCTCCACCGCCTCACACTTTATTGATGCGCTGGCGACCATGAAGGGCCAGATCGAGGGTGCGGTCTCCAGCTCTG
ATGCCTCCACCGCCAGGCTGAAAAGCCTGGGGATCCCGGTCTTTGACCTCAATGAGGTGGATTCGCTGGATATCTATGTG
GATGGGGCCGATGAGATCAACGGCGCCATGCAGATGATCAAGGGCGGCGGCGCCGCGCTGACACGTGAGAAGATCGTGGC
GGCGGTGGCCAAGAAGTTCGTCTGTATCGTCGATGCCTCTAAACAGGTCGATATTCTGGGTAGCTTCCCGCTACCGGTCG
AGGTGATCCCGATGGCGCGCGCCTATGTTGCCCGTGAGCTGGTGAAGCTGGGCGGGCAGCCGGTGTATCGTCAGGGCGTA
CTGACCGACAATGGCAACGTGATCCTGGATGTACACAACCTGCAGATCATGGAGCCGTGCAAACTGGAGAACGCCATTAA
CGCCATCGCCGGCGTCGTGACGGTGGGGCTGTTTGCCAACCGCGGTGCCGACGTTGCGCTGGTCGGCTGCGCGGATGGCG
TCAAAACGCTGACCCTATAA

Upstream 100 bases:

>100_bases
CAGAGAGCAGGCGTAAATTTACGCCGCTGTTGTGGGGTATTTATGCGCGCTGCTCTATAATAACGCACACGTTTTCGTAG
CAAAGTCCATAGGATACGGT

Downstream 100 bases:

>100_bases
TCGCCTCTGGGTGCCCCGCCGTTGCGGGGCGCTGTGCCTGCGGCGGACATTTTTTTCTGCTGTGGTGAAATTCGGTGACA
TCTATCACAGAGTTTAGCCG

Product: ribose 5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTQDELKKAVGWAALKYVRPGTIVGVGTGSTASHFIDALATMKGQIEGAVSSSDASTARLKSLGIPVFDLNEVDSLDIYV
DGADEINGAMQMIKGGGAALTREKIVAAVAKKFVCIVDASKQVDILGSFPLPVEVIPMARAYVARELVKLGGQPVYRQGV
LTDNGNVILDVHNLQIMEPCKLENAINAIAGVVTVGLFANRGADVALVGCADGVKTLTL

Sequences:

>Translated_219_residues
MTQDELKKAVGWAALKYVRPGTIVGVGTGSTASHFIDALATMKGQIEGAVSSSDASTARLKSLGIPVFDLNEVDSLDIYV
DGADEINGAMQMIKGGGAALTREKIVAAVAKKFVCIVDASKQVDILGSFPLPVEVIPMARAYVARELVKLGGQPVYRQGV
LTDNGNVILDVHNLQIMEPCKLENAINAIAGVVTVGLFANRGADVALVGCADGVKTLTL
>Mature_218_residues
TQDELKKAVGWAALKYVRPGTIVGVGTGSTASHFIDALATMKGQIEGAVSSSDASTARLKSLGIPVFDLNEVDSLDIYVD
GADEINGAMQMIKGGGAALTREKIVAAVAKKFVCIVDASKQVDILGSFPLPVEVIPMARAYVARELVKLGGQPVYRQGVL
TDNGNVILDVHNLQIMEPCKLENAINAIAGVVTVGLFANRGADVALVGCADGVKTLTL

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=36.1607142857143, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=84.331797235023, Blast_Score=376, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17551758, Length=224, Percent_Identity=34.375, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=162, Percent_Identity=36.4197530864198, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281364072, Length=208, Percent_Identity=32.2115384615385, Blast_Score=88, Evalue=5e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_EDWI9 (O52398)

Other databases:

- EMBL:   AF037440
- EMBL:   CP001600
- RefSeq:   YP_002934734.1
- ProteinModelPortal:   O52398
- SMR:   O52398
- GeneID:   7959660
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3362
- OMA:   VFDLNSV
- ProtClustDB:   CLSK2813623
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 22838; Mature: 22707

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKKAVGWAALKYVRPGTIVGVGTGSTASHFIDALATMKGQIEGAVSSSDASTARL
CCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSLGIPVFDLNEVDSLDIYVDGADEINGAMQMIKGGGAALTREKIVAAVAKKFVCIVDAS
HHCCCCEEECCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECC
KQVDILGSFPLPVEVIPMARAYVARELVKLGGQPVYRQGVLTDNGNVILDVHNLQIMEPC
CCEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCEEECCEEECCCCEEEEECCCEEECCH
KLENAINAIAGVVTVGLFANRGADVALVGCADGVKTLTL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECC
>Mature Secondary Structure 
TQDELKKAVGWAALKYVRPGTIVGVGTGSTASHFIDALATMKGQIEGAVSSSDASTARL
CHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSLGIPVFDLNEVDSLDIYVDGADEINGAMQMIKGGGAALTREKIVAAVAKKFVCIVDAS
HHCCCCEEECCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECC
KQVDILGSFPLPVEVIPMARAYVARELVKLGGQPVYRQGVLTDNGNVILDVHNLQIMEPC
CCEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCEEECCEEECCCCEEEEECCCEEECCH
KLENAINAIAGVVTVGLFANRGADVALVGCADGVKTLTL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12542086