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The map label for this gene is lpxP [H]

Identifier: 238921156

GI number: 238921156

Start: 3183562

End: 3184488

Strand: Direct

Name: lpxP [H]

Synonym: NT01EI_3298

Alternate gene names: 238921156

Gene position: 3183562-3184488 (Clockwise)

Preceding gene: 238921154

Following gene: 238921159

Centisome position: 83.51

GC content: 60.19

Gene sequence:

>927_bases
ATGAAAAAGCCGCTTCATTTCCGCCACGCATTCCTGCATCCCCGCTACTTCAGCCTATGGCTGGGTATTGGCCTGCTCTA
TCTGCTGGTACAGATGCCCTACCGCTGGCTCTGCGCCCTGGGACGCTTTCTCGGCCTGTGCGCCATGCGGCTGATGGCCC
GGCGCGTCTCCATCGCCCGTCAAAACCTGACGCTATGCTTTCCACAGAAAACGCCAGAACAGATCGAATATATCGTCAGG
GAAAACTTTAAGTCCCTGGGGATCTCGCTGTTTGAGCTCGGCATCGCCTGGTTTTGGTCTGATCGCCGCATCCGCCGCTG
GTTTGATGTCTCCGGTCTGGAGCATATGCAGTCAGCACGGGCGAAAGGAAAAGGAGTACTGGCCGTCGGCGTCCACTTCA
TGTCGCTCGACCTCGGAGGGCGGGTCATGGGGCTGTGTAATCCCATGATGGCGGTCTACCGCCCACATAACAATCCGGTG
CTGGAATACCTGCAGACCCGCGGGCGCTCGCGCGGCAATAAACAGATGCTGGATCGCAAAAACCTGAAAGGGATCGTCGG
AGCGCTGAAAAGCGGCGAGGCGATCTGGTTCGCCCCCGATCAGGACTACGGTCCGCGCGGCAGCTCCTTTGCGCCATTCT
TTGCCGTCAGCAGCGCCGCCACCACCAACGGCACCGCCACCCTGGCCCGGCTATCCAACGCCGTGATACTGACCACCGTC
CTGATCCGCAAACCCGGTGCCCAGGGCTACCAGCTGATTATTGAGCCCGAGCTGGAAGGCTACCCAGCACACGATCTGGT
TCAGGCCGCCACCTTCATGAACCGCATTATCGAGCGCGAGATCCTGCGCGCACCGGAGCAATACCTCTGGCTGCACCGCC
GCTTTAAGACTCGCCCTGAGGGAATGCCGTCGCTGTATACCCGTTAG

Upstream 100 bases:

>100_bases
CAAAGACACAGATAAAAATAACATAAAAAATCATGGCAGTATCATTTTGCCATGGCGATAAAAATAATAAGCAGTTCAAT
AGATAAAAATAAGGTTTTCA

Downstream 100 bases:

>100_bases
GCCACACCGCTCACGGCGCCGTTTACCCGGCAGAGGATATCCTGATAGATATCCGCTGCCGGGCTGACAAACAGATGCCC
AGTGAGACTATTGGTAATGA

Product: hypothetical protein

Products: KDO2-(palmitoleoyl)-lipid IVA [C]

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKKPLHFRHAFLHPRYFSLWLGIGLLYLLVQMPYRWLCALGRFLGLCAMRLMARRVSIARQNLTLCFPQKTPEQIEYIVR
ENFKSLGISLFELGIAWFWSDRRIRRWFDVSGLEHMQSARAKGKGVLAVGVHFMSLDLGGRVMGLCNPMMAVYRPHNNPV
LEYLQTRGRSRGNKQMLDRKNLKGIVGALKSGEAIWFAPDQDYGPRGSSFAPFFAVSSAATTNGTATLARLSNAVILTTV
LIRKPGAQGYQLIIEPELEGYPAHDLVQAATFMNRIIEREILRAPEQYLWLHRRFKTRPEGMPSLYTR

Sequences:

>Translated_308_residues
MKKPLHFRHAFLHPRYFSLWLGIGLLYLLVQMPYRWLCALGRFLGLCAMRLMARRVSIARQNLTLCFPQKTPEQIEYIVR
ENFKSLGISLFELGIAWFWSDRRIRRWFDVSGLEHMQSARAKGKGVLAVGVHFMSLDLGGRVMGLCNPMMAVYRPHNNPV
LEYLQTRGRSRGNKQMLDRKNLKGIVGALKSGEAIWFAPDQDYGPRGSSFAPFFAVSSAATTNGTATLARLSNAVILTTV
LIRKPGAQGYQLIIEPELEGYPAHDLVQAATFMNRIIEREILRAPEQYLWLHRRFKTRPEGMPSLYTR
>Mature_308_residues
MKKPLHFRHAFLHPRYFSLWLGIGLLYLLVQMPYRWLCALGRFLGLCAMRLMARRVSIARQNLTLCFPQKTPEQIEYIVR
ENFKSLGISLFELGIAWFWSDRRIRRWFDVSGLEHMQSARAKGKGVLAVGVHFMSLDLGGRVMGLCNPMMAVYRPHNNPV
LEYLQTRGRSRGNKQMLDRKNLKGIVGALKSGEAIWFAPDQDYGPRGSSFAPFFAVSSAATTNGTATLARLSNAVILTTV
LIRKPGAQGYQLIIEPELEGYPAHDLVQAATFMNRIIEREILRAPEQYLWLHRRFKTRPEGMPSLYTR

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=300, Percent_Identity=62.3333333333333, Blast_Score=403, Evalue=1e-114,
Organism=Escherichia coli, GI1787292, Length=300, Percent_Identity=53, Blast_Score=341, Evalue=4e-95,
Organism=Escherichia coli, GI1788161, Length=309, Percent_Identity=27.1844660194175, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: NA

Molecular weight: Translated: 35243; Mature: 35243

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPLHFRHAFLHPRYFSLWLGIGLLYLLVQMPYRWLCALGRFLGLCAMRLMARRVSIAR
CCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNLTLCFPQKTPEQIEYIVRENFKSLGISLFELGIAWFWSDRRIRRWFDVSGLEHMQSAR
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
AKGKGVLAVGVHFMSLDLGGRVMGLCNPMMAVYRPHNNPVLEYLQTRGRSRGNKQMLDRK
HCCCCEEEEEHEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
NLKGIVGALKSGEAIWFAPDQDYGPRGSSFAPFFAVSSAATTNGTATLARLSNAVILTTV
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHEECCCCCCCCHHHHHHHCCHHHHHHH
LIRKPGAQGYQLIIEPELEGYPAHDLVQAATFMNRIIEREILRAPEQYLWLHRRFKTRPE
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GMPSLYTR
CCCCCCCC
>Mature Secondary Structure
MKKPLHFRHAFLHPRYFSLWLGIGLLYLLVQMPYRWLCALGRFLGLCAMRLMARRVSIAR
CCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNLTLCFPQKTPEQIEYIVRENFKSLGISLFELGIAWFWSDRRIRRWFDVSGLEHMQSAR
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHH
AKGKGVLAVGVHFMSLDLGGRVMGLCNPMMAVYRPHNNPVLEYLQTRGRSRGNKQMLDRK
HCCCCEEEEEHEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
NLKGIVGALKSGEAIWFAPDQDYGPRGSSFAPFFAVSSAATTNGTATLARLSNAVILTTV
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHEECCCCCCCCHHHHHHHCCHHHHHHH
LIRKPGAQGYQLIIEPELEGYPAHDLVQAATFMNRIIEREILRAPEQYLWLHRRFKTRPE
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GMPSLYTR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; palmitoleoyl-ACP [C]

Specific reaction: KDO2-lipid IVA + palmitoleoyl-ACP = KDO2-(palmitoleoyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]