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The map label for this gene is hmp [H]

Identifier: 238921061

GI number: 238921061

Start: 3069231

End: 3070391

Strand: Direct

Name: hmp [H]

Synonym: NT01EI_3191

Alternate gene names: 238921061

Gene position: 3069231-3070391 (Clockwise)

Preceding gene: 238921059

Following gene: 238921063

Centisome position: 80.51

GC content: 60.9

Gene sequence:

>1161_bases
ATGCTGGACACACAAACCATCGTTATCGTCAAATCCACCCTGCCACTGCTGCAACAGTATGGTCCAGGGCTGACCGCCCA
CTTCTATCAACGCATGTTCCGTCATAATCCAGAGCTGAAGTCTCTCTTCAATATGAGTCATCAGCACAGCGGCGATCAGC
GCGAGGCGTTGTTTAACGCCATCTGCGCCTATGCTGCCCACATTGATACCCCCGCGGCGCTGAGCGGGGCGGTAGAGCGT
ATCGCTCATAAACACGTCAGCGTTGGTATTCAACCGCAACAGTACGCCATTATTGGCCATCATCTGCTCAAGACACTGGA
GGAACTATTCAACCCCGGCAGTGATGTGCTGGATGCCTGGAGCAATGCCTACAGCACGCTGGCACAGCTGTTTATTGCAC
GGGAGTCCCAACTGTACCAGGGGCTCGCCGGACAGTCCGGCGGCTGGGCGCATCAGCGGGCGTTTGCGATTGCCGACAAA
CGGGTGGAGAGCGATCTGATCACCAGCTTCACGTTGGTACCGCAGGATGGCGCCCCGATCGCTGACTTCCTCCCAGGGCA
ATATCTGAGCGTATATGTGCGCCATCCCAGCCTCCCGCGCCAGGCGATTCGTCAGTATTCACTGACCCATGCCCCCAATG
GTCAGCATTACCGTATCGCCGTCAAGCGGGAACCTCAGGGCGCCGTCTCCCGCTATCTGCACGACGTCGCCGGTGCGGGT
GATACGCTGCACCTCTCAGCCCCCTGCGGCGGGTTTACTCTAAATACGACGCCGGAGACGCCGCTGGCGCTGATCTCGGC
AGGCGTCGGTGTGACCCCGCTGCTCAGCATGCTGGATACCCTGAGCCGCCGTGGACAACGCGCTTCGCTGTACTGGCTGC
ACGCCGCCGATAGCGACCCCGTGCGCGCCTTTGGCGAGGAGAGCGAGCACCTGCTGGCCACCATCCCCCATCATCACGCG
CATCTGTGCGCTACGCCGCGGCGAACCCACGCAGCCGATCCACGCCCGCTGCCATCGCGGTATGATGGATCTCGGCACCG
TGGGCGACGGGCTGCGCGATCCGCACATGCAGTTCTATTTCTGTGGACCGATTGGCTTTATGCAACATGTGGCACGGCAG
CTGCTGGCACAGGGCGTCGATGCGGAACGACTGCACTATGA

Upstream 100 bases:

>100_bases
CGCCAATGAGGAACATCGGCAATTATTGATTTACAGCGCCACCAAAAATTATTAAGTTGCATTCTATATGCAATTTAATT
GATACCCCCTAGGAGCGCTC

Downstream 100 bases:

>100_bases
GTGCTTCGGCCCACACAAAATTCTGTGATCCCGCCGACCCGTCCATCCTCGCACCGGTAACGCTGGCGCTGCCGCCCGCG
GCGGCTGAGCGGGGAGGGAT

Product: globin domain protein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Hemoprotein X; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MLDTQTIVIVKSTLPLLQQYGPGLTAHFYQRMFRHNPELKSLFNMSHQHSGDQREALFNAICAYAAHIDTPAALSGAVER
IAHKHVSVGIQPQQYAIIGHHLLKTLEELFNPGSDVLDAWSNAYSTLAQLFIARESQLYQGLAGQSGGWAHQRAFAIADK
RVESDLITSFTLVPQDGAPIADFLPGQYLSVYVRHPSLPRQAIRQYSLTHAPNGQHYRIAVKREPQGAVSRYLHDVAGAG
DTLHLSAPCGGFTLNTTPETPLALISAGVGVTPLLSMLDTLSRRGQRASLYWLHAADSDPVRAFGEESEHLLATIPHHHA
HLCATPRRTHAADPRPLPSRYDGSRHRGRRAARSAHAVLFLWTDWLYATCGTAAAGTGRRCGTTAL

Sequences:

>Translated_386_residues
MLDTQTIVIVKSTLPLLQQYGPGLTAHFYQRMFRHNPELKSLFNMSHQHSGDQREALFNAICAYAAHIDTPAALSGAVER
IAHKHVSVGIQPQQYAIIGHHLLKTLEELFNPGSDVLDAWSNAYSTLAQLFIARESQLYQGLAGQSGGWAHQRAFAIADK
RVESDLITSFTLVPQDGAPIADFLPGQYLSVYVRHPSLPRQAIRQYSLTHAPNGQHYRIAVKREPQGAVSRYLHDVAGAG
DTLHLSAPCGGFTLNTTPETPLALISAGVGVTPLLSMLDTLSRRGQRASLYWLHAADSDPVRAFGEESEHLLATIPHHHA
HLCATPRRTHAADPRPLPSRYDGSRHRGRRAARSAHAVLFLWTDWLYATCGTAAAGTGRRCGTTAL
>Mature_386_residues
MLDTQTIVIVKSTLPLLQQYGPGLTAHFYQRMFRHNPELKSLFNMSHQHSGDQREALFNAICAYAAHIDTPAALSGAVER
IAHKHVSVGIQPQQYAIIGHHLLKTLEELFNPGSDVLDAWSNAYSTLAQLFIARESQLYQGLAGQSGGWAHQRAFAIADK
RVESDLITSFTLVPQDGAPIADFLPGQYLSVYVRHPSLPRQAIRQYSLTHAPNGQHYRIAVKREPQGAVSRYLHDVAGAG
DTLHLSAPCGGFTLNTTPETPLALISAGVGVTPLLSMLDTLSRRGQRASLYWLHAADSDPVRAFGEESEHLLATIPHHHA
HLCATPRRTHAADPRPLPSRYDGSRHRGRRAARSAHAVLFLWTDWLYATCGTAAAGTGRRCGTTAL

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=321, Percent_Identity=54.8286604361371, Blast_Score=363, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6321673, Length=332, Percent_Identity=35.5421686746988, Blast_Score=188, Evalue=1e-48,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 42295; Mature: 42295

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTQTIVIVKSTLPLLQQYGPGLTAHFYQRMFRHNPELKSLFNMSHQHSGDQREALFNA
CCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHH
ICAYAAHIDTPAALSGAVERIAHKHVSVGIQPQQYAIIGHHLLKTLEELFNPGSDVLDAW
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SNAYSTLAQLFIARESQLYQGLAGQSGGWAHQRAFAIADKRVESDLITSFTLVPQDGAPI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCH
ADFLPGQYLSVYVRHPSLPRQAIRQYSLTHAPNGQHYRIAVKREPQGAVSRYLHDVAGAG
HHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCC
DTLHLSAPCGGFTLNTTPETPLALISAGVGVTPLLSMLDTLSRRGQRASLYWLHAADSDP
CEEEEECCCCCEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCH
VRAFGEESEHLLATIPHHHAHLCATPRRTHAADPRPLPSRYDGSRHRGRRAARSAHAVLF
HHHCCCCCCCEEEECCCCCHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEE
LWTDWLYATCGTAAAGTGRRCGTTAL
EEHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLDTQTIVIVKSTLPLLQQYGPGLTAHFYQRMFRHNPELKSLFNMSHQHSGDQREALFNA
CCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHH
ICAYAAHIDTPAALSGAVERIAHKHVSVGIQPQQYAIIGHHLLKTLEELFNPGSDVLDAW
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SNAYSTLAQLFIARESQLYQGLAGQSGGWAHQRAFAIADKRVESDLITSFTLVPQDGAPI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCH
ADFLPGQYLSVYVRHPSLPRQAIRQYSLTHAPNGQHYRIAVKREPQGAVSRYLHDVAGAG
HHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCC
DTLHLSAPCGGFTLNTTPETPLALISAGVGVTPLLSMLDTLSRRGQRASLYWLHAADSDP
CEEEEECCCCCEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCH
VRAFGEESEHLLATIPHHHAHLCATPRRTHAADPRPLPSRYDGSRHRGRRAARSAHAVLF
HHHCCCCCCCEEEECCCCCHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEE
LWTDWLYATCGTAAAGTGRRCGTTAL
EEHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7773389 [H]