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The map label for this gene is xseA

Identifier: 238921025

GI number: 238921025

Start: 3036846

End: 3038228

Strand: Direct

Name: xseA

Synonym: NT01EI_3155

Alternate gene names: 238921025

Gene position: 3036846-3038228 (Clockwise)

Preceding gene: 238921020

Following gene: 238921044

Centisome position: 79.66

GC content: 67.17

Gene sequence:

>1383_bases
ATGACGCAGCCTGTTACCCCCACCATCTTTACCGTCAGCCGGTTAAATCAGACCGTGCGCCAGCTGTTGGAGCTGGAGAT
GGGGCAGATTTGGCTGTCGGCCGAAATCTCCAATCTTTCCCAGCCCGCCTCCGGCCACTGGTATTTCACCCTCAAGGATG
ACAAGGCACAGGTGCGTTGCGCCATGTTTCGCAACAGCAACCGCCGCGTGACCTTTCGTCCGCAGAATGGCCAGCAGGTC
CTGGTTCGCGCCAGTATCACGCTGTATGAATCGCGCGGCGACTATCAGCTGATCGCCGAAAGTATGCAGCCTGCGGGCGA
CGGCCTGCTGCAGCAGCAGTTCGAGGCGCTCAAACAGCGTCTGCAGGCCGAAGGGCTATTTGACGTCGGCCACAAACAGC
CGCTGCCGTCACCGGCACGCTGCGTCGGGGTGATCACCTCCACCAGCGGTGCAGCGCTGCACGACGTGCTACACGTGCTG
CGCCGACGCGATCCGGCCCTGCCGGTGGTGATCTACCCCAGCGCGGTGCAAGGTGGCGAGGCGCCCGGGCAGCTGGTGCG
CGCAATTGCACTGGCCAACCTGCGCGCGGAGTGCGACGTGCTGATCGTCGGGCGCGGCGGCGGTTCCCTGGAAGATCTGT
GGAGCTTCAACGATGAACGGGTCGCGCGGGCGATCTTCGCCAGCCATATTCCCATCGTCAGCGCCGTCGGCCATGAGACC
GACGTCAGCATCGCCGACTTTGTCGCCGATCTGCGCGCGCCGACCCCCTCGGCGGCGGCCGAAGTGGTCAGCCGTAACCG
GGACGAACTGCTGCGCCGTCTGCTGAGCCAGCGTCAGCGGCTGGATATGGCGCTGGATTATACCCTCGCGCGCCGCCGTC
AGCGCCTACAGCAGCTGCGTCACCGCCTGGAGCAACAGCACCCCCAGCTGCGTCTGGCGCGCCAGCAGGCGCGACTGCTT
AGCCTGCACCGCCGCCTGGAGGAGGCCATCGATACCCAGCTACGCCTGGCGGAGCGACGCTGGCGCCTGGGTGGAGAACG
CCTACAGCAGCGCTCTCCGGCGCATGCCCTGCGCCAGCAGCAGTACCACCTGCAGCAGCTCAGCCACCGTTTGGAAAGTC
AGCTACAGCGCAGCGTGGCCGCCCGGCGGGAGCGCTTTGGCGCCCTGTGCTCTCGCCTGGAGGGCATGAGCCCGCTGGCG
ACGCTGGCGCGCGGCTTCAGCGTGACCCAGCGCGATGACGGTCAGCTACTGCGCCACCGCGAGCAGGTCGCTCCGGGAGA
TACCCTGCGCACCCGCCTGGAGGACGGCTGGGTCGAAAGTCAGGTCACCGCGACCCGGCCACTGACTGCCCGCCGCCCCC
GCGGGACAAAGGGCAGCGCGTAG

Upstream 100 bases:

>100_bases
GGTTGCCTCCAGCATTTTTTTCAGAAATATCTTGCGATGCATAGCCATGCATGTAGTATCGACTAATTAACAGTATGATT
TTAAGTTTGATCCAGGTCAC

Downstream 100 bases:

>100_bases
CCCCCGTTGTGACTATCCCTGTCGCTGCATCATTCGGGCGGTGGCGATAGCCTCGATCAGCTGACGCCGGTTAATCCGCG
CAGATCCGCCGTCCAGCAGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTQPVTPTIFTVSRLNQTVRQLLELEMGQIWLSAEISNLSQPASGHWYFTLKDDKAQVRCAMFRNSNRRVTFRPQNGQQV
LVRASITLYESRGDYQLIAESMQPAGDGLLQQQFEALKQRLQAEGLFDVGHKQPLPSPARCVGVITSTSGAALHDVLHVL
RRRDPALPVVIYPSAVQGGEAPGQLVRAIALANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFASHIPIVSAVGHET
DVSIADFVADLRAPTPSAAAEVVSRNRDELLRRLLSQRQRLDMALDYTLARRRQRLQQLRHRLEQQHPQLRLARQQARLL
SLHRRLEEAIDTQLRLAERRWRLGGERLQQRSPAHALRQQQYHLQQLSHRLESQLQRSVAARRERFGALCSRLEGMSPLA
TLARGFSVTQRDDGQLLRHREQVAPGDTLRTRLEDGWVESQVTATRPLTARRPRGTKGSA

Sequences:

>Translated_460_residues
MTQPVTPTIFTVSRLNQTVRQLLELEMGQIWLSAEISNLSQPASGHWYFTLKDDKAQVRCAMFRNSNRRVTFRPQNGQQV
LVRASITLYESRGDYQLIAESMQPAGDGLLQQQFEALKQRLQAEGLFDVGHKQPLPSPARCVGVITSTSGAALHDVLHVL
RRRDPALPVVIYPSAVQGGEAPGQLVRAIALANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFASHIPIVSAVGHET
DVSIADFVADLRAPTPSAAAEVVSRNRDELLRRLLSQRQRLDMALDYTLARRRQRLQQLRHRLEQQHPQLRLARQQARLL
SLHRRLEEAIDTQLRLAERRWRLGGERLQQRSPAHALRQQQYHLQQLSHRLESQLQRSVAARRERFGALCSRLEGMSPLA
TLARGFSVTQRDDGQLLRHREQVAPGDTLRTRLEDGWVESQVTATRPLTARRPRGTKGSA
>Mature_459_residues
TQPVTPTIFTVSRLNQTVRQLLELEMGQIWLSAEISNLSQPASGHWYFTLKDDKAQVRCAMFRNSNRRVTFRPQNGQQVL
VRASITLYESRGDYQLIAESMQPAGDGLLQQQFEALKQRLQAEGLFDVGHKQPLPSPARCVGVITSTSGAALHDVLHVLR
RRDPALPVVIYPSAVQGGEAPGQLVRAIALANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFASHIPIVSAVGHETD
VSIADFVADLRAPTPSAAAEVVSRNRDELLRRLLSQRQRLDMALDYTLARRRQRLQQLRHRLEQQHPQLRLARQQARLLS
LHRRLEEAIDTQLRLAERRWRLGGERLQQRSPAHALRQQQYHLQQLSHRLESQLQRSVAARRERFGALCSRLEGMSPLAT
LARGFSVTQRDDGQLLRHREQVAPGDTLRTRLEDGWVESQVTATRPLTARRPRGTKGSA

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=449, Percent_Identity=68.1514476614699, Blast_Score=630, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_EDWI9 (C5BER7)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934540.1
- GeneID:   7958673
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3155
- OMA:   EISNFTR
- ProtClustDB:   PRK00286
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 51901; Mature: 51770

Theoretical pI: Translated: 11.39; Mature: 11.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPVTPTIFTVSRLNQTVRQLLELEMGQIWLSAEISNLSQPASGHWYFTLKDDKAQVRC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCCCCCCCEEEEEECCCHHHHH
AMFRNSNRRVTFRPQNGQQVLVRASITLYESRGDYQLIAESMQPAGDGLLQQQFEALKQR
HHEECCCCEEEECCCCCCEEEEEEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
LQAEGLFDVGHKQPLPSPARCVGVITSTSGAALHDVLHVLRRRDPALPVVIYPSAVQGGE
HHHCCCCCCCCCCCCCCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
APGQLVRAIALANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFASHIPIVSAVGHET
CHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCC
DVSIADFVADLRAPTPSAAAEVVSRNRDELLRRLLSQRQRLDMALDYTLARRRQRLQQLR
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRLEQQHPQLRLARQQARLLSLHRRLEEAIDTQLRLAERRWRLGGERLQQRSPAHALRQQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHH
QYHLQQLSHRLESQLQRSVAARRERFGALCSRLEGMSPLATLARGFSVTQRDDGQLLRHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHH
EQVAPGDTLRTRLEDGWVESQVTATRPLTARRPRGTKGSA
HHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQPVTPTIFTVSRLNQTVRQLLELEMGQIWLSAEISNLSQPASGHWYFTLKDDKAQVRC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCCCCCCCEEEEEECCCHHHHH
AMFRNSNRRVTFRPQNGQQVLVRASITLYESRGDYQLIAESMQPAGDGLLQQQFEALKQR
HHEECCCCEEEECCCCCCEEEEEEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
LQAEGLFDVGHKQPLPSPARCVGVITSTSGAALHDVLHVLRRRDPALPVVIYPSAVQGGE
HHHCCCCCCCCCCCCCCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
APGQLVRAIALANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFASHIPIVSAVGHET
CHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCC
DVSIADFVADLRAPTPSAAAEVVSRNRDELLRRLLSQRQRLDMALDYTLARRRQRLQQLR
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRLEQQHPQLRLARQQARLLSLHRRLEEAIDTQLRLAERRWRLGGERLQQRSPAHALRQQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHH
QYHLQQLSHRLESQLQRSVAARRERFGALCSRLEGMSPLATLARGFSVTQRDDGQLLRHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHH
EQVAPGDTLRTRLEDGWVESQVTATRPLTARRPRGTKGSA
HHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA