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The map label for this gene is dam [H]

Identifier: 238921006

GI number: 238921006

Start: 3017691

End: 3018449

Strand: Direct

Name: dam [H]

Synonym: NT01EI_3136

Alternate gene names: 238921006

Gene position: 3017691-3018449 (Clockwise)

Preceding gene: 238921005

Following gene: 238921007

Centisome position: 79.16

GC content: 53.89

Gene sequence:

>759_bases
ATGAATACATTACCCGTTATTCCGTGGATCGGCGGCAAGCGCCGGCTGGCAAAACACATCCTGCCGCTGTTTCCTGAACA
CCGCTGTTATGTCGAACCGTTCTGCGGAGCGGCGGCGTTGTTCTTTATGAAGAAACCCACTCAGGTGGAGGTGCTGAACG
ATATCAACGGTGACGTGACCAACCTCTATCGCGTACTCCAGCACCATTTAGAAGAATTCGTGCGTCAGTTTAAGTGGTCG
CTGGTCAGCCGCGAAATGTACCGCTGGCTCCAGATCACTCCGGAAGAAACGTTGACCGATATCCAGCGCGCAGCCCGCTT
CTATTACCTGCAAAAACTGGCGTTCGGTGGCAAAGTGGAAAACCGCACATTCGGCACCGCCACCACCTCGCCACCGCGCC
TGAATCTGCTGCGTATGGAAGAGGATTTATCCGCCGCCCATCTGCGGCTAACGCGCGTTTGTATTGAAAATCTGGATTGG
GCCGACTGTATTCGCCGCTATGACCGCCCGCATACCCTGTTCTACTGCGACCCACCATACTGGAAAACCGAAGGCTACGG
CGTATCGTTTGGCCTTGAGCTGTACCTGCGTATGGCAGAGCTGGCGCGCACCATGCAGGGCCGGATGATTATCTCGGTTA
ATGACATCCCGGAAATGCGTAATATCTTCCACGGCCTGACATTCTCAACGGTAGAAATTCGCTATACCGTAGGAGGAAAG
CCAGCCAGCGCCACATCAGAGTTGATTATTCAGAATTAA

Upstream 100 bases:

>100_bases
TGATACGCCTGCCCTGCCACCCATATGAATTGTGAGGTTAGCGTTATTCACCTAATCTGCTGCATGCGCTGATCAGTAGC
CGGTCAGGTAGATTGACAAT

Downstream 100 bases:

>100_bases
AAACCGCTTCCGCTTGTAGTGCCAGTGATTACAAGTGGAAGCCATCACCGCCCTTTTCGCTCTGTGCCACCATCGTCATT
TATTGACCTGATGGAGGCTC

Product: DNA adenine methylase

Products: NA

Alternate protein names: DNA adenine methyltransferase; Deoxyadenosyl-methyltransferase; M.HindIV [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNTLPVIPWIGGKRRLAKHILPLFPEHRCYVEPFCGAAALFFMKKPTQVEVLNDINGDVTNLYRVLQHHLEEFVRQFKWS
LVSREMYRWLQITPEETLTDIQRAARFYYLQKLAFGGKVENRTFGTATTSPPRLNLLRMEEDLSAAHLRLTRVCIENLDW
ADCIRRYDRPHTLFYCDPPYWKTEGYGVSFGLELYLRMAELARTMQGRMIISVNDIPEMRNIFHGLTFSTVEIRYTVGGK
PASATSELIIQN

Sequences:

>Translated_252_residues
MNTLPVIPWIGGKRRLAKHILPLFPEHRCYVEPFCGAAALFFMKKPTQVEVLNDINGDVTNLYRVLQHHLEEFVRQFKWS
LVSREMYRWLQITPEETLTDIQRAARFYYLQKLAFGGKVENRTFGTATTSPPRLNLLRMEEDLSAAHLRLTRVCIENLDW
ADCIRRYDRPHTLFYCDPPYWKTEGYGVSFGLELYLRMAELARTMQGRMIISVNDIPEMRNIFHGLTFSTVEIRYTVGGK
PASATSELIIQN
>Mature_252_residues
MNTLPVIPWIGGKRRLAKHILPLFPEHRCYVEPFCGAAALFFMKKPTQVEVLNDINGDVTNLYRVLQHHLEEFVRQFKWS
LVSREMYRWLQITPEETLTDIQRAARFYYLQKLAFGGKVENRTFGTATTSPPRLNLLRMEEDLSAAHLRLTRVCIENLDW
ADCIRRYDRPHTLFYCDPPYWKTEGYGVSFGLELYLRMAELARTMQGRMIISVNDIPEMRNIFHGLTFSTVEIRYTVGGK
PASATSELIIQN

Specific function: Methylates DNA within the sequence GATC. Directly involved in methyl-directed DNA mismatch repair [H]

COG id: COG0338

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789789, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023095
- InterPro:   IPR002052
- InterPro:   IPR012327 [H]

Pfam domain/function: PF02086 MethyltransfD12 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 29380; Mature: 29380

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLPVIPWIGGKRRLAKHILPLFPEHRCYVEPFCGAAALFFMKKPTQVEVLNDINGDVT
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHCCCCCEEEECCCCCCHH
NLYRVLQHHLEEFVRQFKWSLVSREMYRWLQITPEETLTDIQRAARFYYLQKLAFGGKVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
NRTFGTATTSPPRLNLLRMEEDLSAAHLRLTRVCIENLDWADCIRRYDRPHTLFYCDPPY
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCC
WKTEGYGVSFGLELYLRMAELARTMQGRMIISVNDIPEMRNIFHGLTFSTVEIRYTVGGK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEEEEEEEEECCC
PASATSELIIQN
CCCCCCHHEECC
>Mature Secondary Structure
MNTLPVIPWIGGKRRLAKHILPLFPEHRCYVEPFCGAAALFFMKKPTQVEVLNDINGDVT
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHCCCCCEEEECCCCCCHH
NLYRVLQHHLEEFVRQFKWSLVSREMYRWLQITPEETLTDIQRAARFYYLQKLAFGGKVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
NRTFGTATTSPPRLNLLRMEEDLSAAHLRLTRVCIENLDWADCIRRYDRPHTLFYCDPPY
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCC
WKTEGYGVSFGLELYLRMAELARTMQGRMIISVNDIPEMRNIFHGLTFSTVEIRYTVGGK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEEEEEEEEECCC
PASATSELIIQN
CCCCCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]