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The map label for this gene is modD [H]

Identifier: 238920846

GI number: 238920846

Start: 2859268

End: 2860116

Strand: Direct

Name: modD [H]

Synonym: NT01EI_2972

Alternate gene names: 238920846

Gene position: 2859268-2860116 (Clockwise)

Preceding gene: 238920845

Following gene: 238920849

Centisome position: 75.0

GC content: 65.14

Gene sequence:

>849_bases
ATGATTTTTATCAGCGACAGCCAGCTGGACGCCTGGCTGCAGGAGGATATCCAGGGGGGCGATATCACCACCCGCGCCCT
GGGGATCGGTGAACGGCACGGTGAGATGCATTTTTACCACCGCCAGGGGGGCTGCGTCAGCGCCATCGCCCTCACCTGCC
GCATGCTGGCCAGACTGGGGCTGGAGACCATCGCTGCCGTGCGCGACGGCGATCGGGTCGTGCCCGGCGCCCTGCTGCTG
CAGGCCCGCGGCAGCGCCGTCGCACTGCATCAGGGCTGGAAAGCCAGCCAGAATCTGCTGGAGTGGAGCTGCGGGGTCAG
TGACTGCGCAGCCCGTATGGTAGATATCCTGCGCCGCTACCAGCCAGAAGGGCAGATAGCCTGTACCCGCAAGTCGATCC
CTGGCACCCGGCTGGCGGCCATGCAGGCGGTGCTCGACGGCGGCGCCATTCTGCACCGCACCGGCTGCGCTGAAACCGTT
CTGCTGTTTACCAACCACCGACGTTTCTGGCCAGAGCCCGATGACTGGCAGGGTATGGTGACACGCCTGCGTCGCCAGGC
GCCGGAAAAGAGCCTGATCGTCGAGGTGGATACCCCGCAGGAAGCCGAGGCAGCGCTGGCCGCACAGCCCGATATTCTGC
AGCTGGATAAGTTCACCCCGGCGCAGATAGCGAAGATCCAGACGCAGGCGGCCACGCTGGCCCCCTGCTGCCGCCTGTCG
CTGGCCGGCGGAATTAACCTGAACAGCATTGAGGCCATCGCCCAGATGGGCGTTGGACTGCTGATCACCTCAGCACCTTA
CCACGCGGCACCGGCGGACATTAAAGTCCGCCTAATGCCCTGCACCTAA

Upstream 100 bases:

>100_bases
ATTATCATCACTGCCGGCAGCGGGGACGCGCACCGGCCGGAGCACGACGTGACTGGGCGCTGATCGCCTGGCAACCGCAG
CCATTAACGGAGGATCGGGA

Downstream 100 bases:

>100_bases
CCCTGCAACGGGGAACACCATGCCCCGGCGTCGGCTTAAAAGCGCCAGCCAACGCCCAGGTTAAAGCCGCTAGGGGGCTA
CCACCGGCGGACGGTAGCCC

Product: molybdenum transport protein ModD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MIFISDSQLDAWLQEDIQGGDITTRALGIGERHGEMHFYHRQGGCVSAIALTCRMLARLGLETIAAVRDGDRVVPGALLL
QARGSAVALHQGWKASQNLLEWSCGVSDCAARMVDILRRYQPEGQIACTRKSIPGTRLAAMQAVLDGGAILHRTGCAETV
LLFTNHRRFWPEPDDWQGMVTRLRRQAPEKSLIVEVDTPQEAEAALAAQPDILQLDKFTPAQIAKIQTQAATLAPCCRLS
LAGGINLNSIEAIAQMGVGLLITSAPYHAAPADIKVRLMPCT

Sequences:

>Translated_282_residues
MIFISDSQLDAWLQEDIQGGDITTRALGIGERHGEMHFYHRQGGCVSAIALTCRMLARLGLETIAAVRDGDRVVPGALLL
QARGSAVALHQGWKASQNLLEWSCGVSDCAARMVDILRRYQPEGQIACTRKSIPGTRLAAMQAVLDGGAILHRTGCAETV
LLFTNHRRFWPEPDDWQGMVTRLRRQAPEKSLIVEVDTPQEAEAALAAQPDILQLDKFTPAQIAKIQTQAATLAPCCRLS
LAGGINLNSIEAIAQMGVGLLITSAPYHAAPADIKVRLMPCT
>Mature_282_residues
MIFISDSQLDAWLQEDIQGGDITTRALGIGERHGEMHFYHRQGGCVSAIALTCRMLARLGLETIAAVRDGDRVVPGALLL
QARGSAVALHQGWKASQNLLEWSCGVSDCAARMVDILRRYQPEGQIACTRKSIPGTRLAAMQAVLDGGAILHRTGCAETV
LLFTNHRRFWPEPDDWQGMVTRLRRQAPEKSLIVEVDTPQEAEAALAAQPDILQLDKFTPAQIAKIQTQAATLAPCCRLS
LAGGINLNSIEAIAQMGVGLLITSAPYHAAPADIKVRLMPCT

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Homo sapiens, GI45269149, Length=274, Percent_Identity=27.007299270073, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786299, Length=223, Percent_Identity=27.3542600896861, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321162, Length=287, Percent_Identity=22.6480836236934, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 30555; Mature: 30555

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFISDSQLDAWLQEDIQGGDITTRALGIGERHGEMHFYHRQGGCVSAIALTCRMLARLG
CEEECCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHC
LETIAAVRDGDRVVPGALLLQARGSAVALHQGWKASQNLLEWSCGVSDCAARMVDILRRY
HHHHHHHCCCCEECCHHEEEECCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
QPEGQIACTRKSIPGTRLAAMQAVLDGGAILHRTGCAETVLLFTNHRRFWPEPDDWQGMV
CCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCCCCCHHHHH
TRLRRQAPEKSLIVEVDTPQEAEAALAAQPDILQLDKFTPAQIAKIQTQAATLAPCCRLS
HHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
LAGGINLNSIEAIAQMGVGLLITSAPYHAAPADIKVRLMPCT
HCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MIFISDSQLDAWLQEDIQGGDITTRALGIGERHGEMHFYHRQGGCVSAIALTCRMLARLG
CEEECCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHC
LETIAAVRDGDRVVPGALLLQARGSAVALHQGWKASQNLLEWSCGVSDCAARMVDILRRY
HHHHHHHCCCCEECCHHEEEECCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
QPEGQIACTRKSIPGTRLAAMQAVLDGGAILHRTGCAETVLLFTNHRRFWPEPDDWQGMV
CCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCCCCCHHHHH
TRLRRQAPEKSLIVEVDTPQEAEAALAAQPDILQLDKFTPAQIAKIQTQAATLAPCCRLS
HHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
LAGGINLNSIEAIAQMGVGLLITSAPYHAAPADIKVRLMPCT
HCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA