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The map label for this gene is lipB [H]

Identifier: 238920821

GI number: 238920821

Start: 2835625

End: 2836293

Strand: Direct

Name: lipB [H]

Synonym: NT01EI_2947

Alternate gene names: 238920821

Gene position: 2835625-2836293 (Clockwise)

Preceding gene: 238920820

Following gene: 238920822

Centisome position: 74.38

GC content: 59.19

Gene sequence:

>669_bases
ATGACGCCATTGCAACAAAAAACCATAATACTGCGTCAGTTGGGGCTACAGCCCTATCTCTCCGTCTCACAGGCCATGCA
CCGCTTCACCGATCGCCGTGACGCCGATACCCCTGACGAGCTGTGGCTGGTAGAGCATCCCGCCGTATTTACCCAGGGGC
AGGCCGGTAAGGCTGAGCATTTGCTCAATCCCGGTGATATCCCGGTTATCCAGAGCGATCGCGGCGGCCAGGTCACCTAT
CACGGGCCGGGCCAGCAGGTGATGTATGTTCTTATCGATCTGCGCCGCGGCCACCGCGGCGTGCGTGAACTGGTCAGTTG
GCTTGAAGAGAGCGTGGTACGCACCCTGTCAGAGCTGGATATTCAGGCCTATCCACGCCCCGATGCACCAGGCGTCTACG
TTGACGGACAGAAAATCTGCTCCCTTGGCCTGCGCATCCGTAAGGGGTGCTCTTTCCACGGTCTGGCGCTGAACATCGCC
ATGGATCTCTCTCCCTTCCAACGCATTAATCCCTGCGGCTATGCCGGCCTGCAGATGACCCAGATAAGCGCGCTGAGGCC
GGGGGCAACCCTGACGCAGGTTCAGCCCCGCTTGGTGCACCATTTTACCCAACTGCTCGGCTATACCCGGCTTGAGCACA
GCCAGTGGAATCCGCAAGACTATGAGTAA

Upstream 100 bases:

>100_bases
TGGCGTTACAGCTTGCCGGGCCGTACTTTTTTGCCGATTCGGCACTGGTGAGTATGGGCGACAATCGGTATAATGGACTT
ACCAATTTTTTAACCTTAAG

Downstream 100 bases:

>100_bases
ACCAATTCAGATGGAGCGCGGCGTGAAATACCGCGACGCAGACAAGATGGCCCTGATCCCGGTGAAATCCGTCGCTGTTG
AGCGTGAACAGCTGCTGCGC

Product: lipoyl(octanoyl) transferase

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTPLQQKTIILRQLGLQPYLSVSQAMHRFTDRRDADTPDELWLVEHPAVFTQGQAGKAEHLLNPGDIPVIQSDRGGQVTY
HGPGQQVMYVLIDLRRGHRGVRELVSWLEESVVRTLSELDIQAYPRPDAPGVYVDGQKICSLGLRIRKGCSFHGLALNIA
MDLSPFQRINPCGYAGLQMTQISALRPGATLTQVQPRLVHHFTQLLGYTRLEHSQWNPQDYE

Sequences:

>Translated_222_residues
MTPLQQKTIILRQLGLQPYLSVSQAMHRFTDRRDADTPDELWLVEHPAVFTQGQAGKAEHLLNPGDIPVIQSDRGGQVTY
HGPGQQVMYVLIDLRRGHRGVRELVSWLEESVVRTLSELDIQAYPRPDAPGVYVDGQKICSLGLRIRKGCSFHGLALNIA
MDLSPFQRINPCGYAGLQMTQISALRPGATLTQVQPRLVHHFTQLLGYTRLEHSQWNPQDYE
>Mature_221_residues
TPLQQKTIILRQLGLQPYLSVSQAMHRFTDRRDADTPDELWLVEHPAVFTQGQAGKAEHLLNPGDIPVIQSDRGGQVTYH
GPGQQVMYVLIDLRRGHRGVRELVSWLEESVVRTLSELDIQAYPRPDAPGVYVDGQKICSLGLRIRKGCSFHGLALNIAM
DLSPFQRINPCGYAGLQMTQISALRPGATLTQVQPRLVHHFTQLLGYTRLEHSQWNPQDYE

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=233, Percent_Identity=32.618025751073, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI87081767, Length=210, Percent_Identity=68.0952380952381, Blast_Score=300, Evalue=6e-83,
Organism=Saccharomyces cerevisiae, GI6323268, Length=163, Percent_Identity=34.3558282208589, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355483, Length=154, Percent_Identity=32.4675324675325, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 25028; Mature: 24897

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLQQKTIILRQLGLQPYLSVSQAMHRFTDRRDADTPDELWLVEHPAVFTQGQAGKAEH
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCCCHHH
LLNPGDIPVIQSDRGGQVTYHGPGQQVMYVLIDLRRGHRGVRELVSWLEESVVRTLSELD
CCCCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
IQAYPRPDAPGVYVDGQKICSLGLRIRKGCSFHGLALNIAMDLSPFQRINPCGYAGLQMT
CCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCHH
QISALRPGATLTQVQPRLVHHFTQLLGYTRLEHSQWNPQDYE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TPLQQKTIILRQLGLQPYLSVSQAMHRFTDRRDADTPDELWLVEHPAVFTQGQAGKAEH
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCCCHHH
LLNPGDIPVIQSDRGGQVTYHGPGQQVMYVLIDLRRGHRGVRELVSWLEESVVRTLSELD
CCCCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
IQAYPRPDAPGVYVDGQKICSLGLRIRKGCSFHGLALNIAMDLSPFQRINPCGYAGLQMT
CCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCHH
QISALRPGATLTQVQPRLVHHFTQLLGYTRLEHSQWNPQDYE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA