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The map label for this gene is rihA [H]

Identifier: 238920808

GI number: 238920808

Start: 2822543

End: 2822725

Strand: Direct

Name: rihA [H]

Synonym: NT01EI_2934

Alternate gene names: 238920808

Gene position: 2822543-2822725 (Clockwise)

Preceding gene: 238920806

Following gene: 238920810

Centisome position: 74.04

GC content: 63.93

Gene sequence:

>183_bases
GTGGAAACCCGCGGACGCTATACCACCGGAATGACGGTAGTGGATGCCTACGTCCTGAGCGGCAACGCCCCCAATGCCAC
CGTGCTGCTGGACGTCGATCGCCAGGCCTTTGTCGATCTGCTGGCTGAACGGATCGCCACCTATGGCGACATGACAGAGG
AGCTCCCCGGCGAGCGCCGGTGA

Upstream 100 bases:

>100_bases
GAAGAGATAGGGCTTGCAAGGAGCGCCGCTGCACGCCCCCTGCACCATCGCCTGACTGCTGCGCCCGCAGATCTTTACCA
GCGTAGAACGCTGGGTGGGA

Downstream 100 bases:

>100_bases
TCGTCCCCGCGGGGAAATGCGCCCGCCGCCCACGGCGGGCGAACCCTCAGGGGCGGAAGGGGCGGCGGTGAAACTGATCG
TGGCCGCAGCGCGGACAGCG

Product: pyrimidine-specific ribonucleoside hydrolase RihA

Products: uracil; ribose; cytosine [C]

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 60; Mature: 60

Protein sequence:

>60_residues
METRGRYTTGMTVVDAYVLSGNAPNATVLLDVDRQAFVDLLAERIATYGDMTEELPGERR

Sequences:

>Translated_60_residues
METRGRYTTGMTVVDAYVLSGNAPNATVLLDVDRQAFVDLLAERIATYGDMTEELPGERR
>Mature_60_residues
METRGRYTTGMTVVDAYVLSGNAPNATVLLDVDRQAFVDLLAERIATYGDMTEELPGERR

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=49, Percent_Identity=67.3469387755102, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: NA

Molecular weight: Translated: 6651; Mature: 6651

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRGRYTTGMTVVDAYVLSGNAPNATVLLDVDRQAFVDLLAERIATYGDMTEELPGERR
CCCCCCCCCCHHEEHEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCHHCCCCCCC
>Mature Secondary Structure
METRGRYTTGMTVVDAYVLSGNAPNATVLLDVDRQAFVDLLAERIATYGDMTEELPGERR
CCCCCCCCCCHHEEHEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: uridine; H2O; cytidine [C]

Specific reaction: uridine + H2O = uracil + ribose cytidine + H2O = cytosine + ribose [C]

General reaction: Pyrimidine-specific nucleoside hydrolase [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA