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The map label for this gene is arcB [H]

Identifier: 238917598

GI number: 238917598

Start: 1735700

End: 1736695

Strand: Reverse

Name: arcB [H]

Synonym: EUBELI_01677

Alternate gene names: 238917598

Gene position: 1736695-1735700 (Counterclockwise)

Preceding gene: 238917599

Following gene: 238917597

Centisome position: 81.0

GC content: 41.37

Gene sequence:

>996_bases
ATGGATTTAAAGGGACGCGACTTTTTAACACTCAAGGATTACACACCTGAGGAGATTTTATATTTGATAGACTTAGCAGC
AGAGCTTAAGGATAAGAAGAAAAAGGGCATTGTAGAACAGCCACTTATCGGAAAGAATGTTGCACTTATATTCGAGAAGA
CAAGTACAAGAACACGTTGCTCATTTGAGGTGGCAGCACATGATCTTGGTATGGGTGTTACATATCTTGACCCTACAGGT
TCACAGATTGGCAAGAAGGAGAGCATTGCTGATACAGCAAGAGTTCTCTGTACAATGTTTGAAGGAATCGAATACAGAGG
ATTCGGTCAGGAGATAGTTGAAGACCTTGCAAAATATTCAAGCGTGCCTGTATGGAACGGACTTACTAACGAATACCATC
CAACACAGATGCTTGCAGATATGCTTACAATCAAGGAAAAGCTTGGCAGATTAAAGGGCGTTAAGTTCGTATACATGGGT
GATGCAAGATACAACATGGGTAATTCACTTATGATTGTCTGCGCTAAGTTAGGACTTCATTATACAGCCTGCACAGCTAA
GGAATATTTCCCAGACAAGGAACTTGTTGCACAGTGTGAGGAATGGGCAAAGATAAGCGGTGGTTCTGTAACACTTACAG
AAGATGTTAAGGCAGGAACTAAGGACGCAGATGTATTATACACAGATGTATGGGTATCAATGGGCGAGCCTGATGAAGTA
TGGGCTGAAAGAATCAAGGCACTTCTTCCATATCAGGTTAACAAGGCAGTTATGGACAATGCTTCTAAGGACGCAATATT
TATGCACTGTCTTCCTGCATTCCATGACCTTAAGACTAAGATTGGTAAAGAGATTCATGACAAATTCGGTCTTGACGAGA
TGGAAGTTACTGATGAAGTATTTGAGTCAGAGCAGTCAGTTGTATTCGACGAGGCAGAGAACAGAATGCATACAATCAAG
GCTGTAATGGCAGCTACACTTGGAGCTTATAAGTAA

Upstream 100 bases:

>100_bases
TTAAACAACGCATTTGACGAAGGACTATAATTGCGATAGAATGAACAAAGTTATTAATTATTCAATGTAGGCGAATTTGC
CATACAGACAGGAGGATGTC

Downstream 100 bases:

>100_bases
ATTGGACGTTAGAGTGGCGTGTGTCATGCCGGAAGTCCAAAATCGGGAAGCCGACACGCGGAATTGGACGTTAGAGCAGT
GGAAAGACATGTGAAAGTCC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MDLKGRDFLTLKDYTPEEILYLIDLAAELKDKKKKGIVEQPLIGKNVALIFEKTSTRTRCSFEVAAHDLGMGVTYLDPTG
SQIGKKESIADTARVLCTMFEGIEYRGFGQEIVEDLAKYSSVPVWNGLTNEYHPTQMLADMLTIKEKLGRLKGVKFVYMG
DARYNMGNSLMIVCAKLGLHYTACTAKEYFPDKELVAQCEEWAKISGGSVTLTEDVKAGTKDADVLYTDVWVSMGEPDEV
WAERIKALLPYQVNKAVMDNASKDAIFMHCLPAFHDLKTKIGKEIHDKFGLDEMEVTDEVFESEQSVVFDEAENRMHTIK
AVMAATLGAYK

Sequences:

>Translated_331_residues
MDLKGRDFLTLKDYTPEEILYLIDLAAELKDKKKKGIVEQPLIGKNVALIFEKTSTRTRCSFEVAAHDLGMGVTYLDPTG
SQIGKKESIADTARVLCTMFEGIEYRGFGQEIVEDLAKYSSVPVWNGLTNEYHPTQMLADMLTIKEKLGRLKGVKFVYMG
DARYNMGNSLMIVCAKLGLHYTACTAKEYFPDKELVAQCEEWAKISGGSVTLTEDVKAGTKDADVLYTDVWVSMGEPDEV
WAERIKALLPYQVNKAVMDNASKDAIFMHCLPAFHDLKTKIGKEIHDKFGLDEMEVTDEVFESEQSVVFDEAENRMHTIK
AVMAATLGAYK
>Mature_331_residues
MDLKGRDFLTLKDYTPEEILYLIDLAAELKDKKKKGIVEQPLIGKNVALIFEKTSTRTRCSFEVAAHDLGMGVTYLDPTG
SQIGKKESIADTARVLCTMFEGIEYRGFGQEIVEDLAKYSSVPVWNGLTNEYHPTQMLADMLTIKEKLGRLKGVKFVYMG
DARYNMGNSLMIVCAKLGLHYTACTAKEYFPDKELVAQCEEWAKISGGSVTLTEDVKAGTKDADVLYTDVWVSMGEPDEV
WAERIKALLPYQVNKAVMDNASKDAIFMHCLPAFHDLKTKIGKEIHDKFGLDEMEVTDEVFESEQSVVFDEAENRMHTIK
AVMAATLGAYK

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=331, Percent_Identity=41.0876132930514, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI18105007, Length=340, Percent_Identity=25.2941176470588, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=59.8159509202454, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1786469, Length=333, Percent_Identity=59.7597597597598, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI48994908, Length=371, Percent_Identity=26.6846361185984, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367364, Length=294, Percent_Identity=29.2517006802721, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=350, Percent_Identity=24.8571428571429, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322373, Length=335, Percent_Identity=32.5373134328358, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6322331, Length=285, Percent_Identity=29.4736842105263, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24642586, Length=339, Percent_Identity=25.6637168141593, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37091; Mature: 37091

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKGRDFLTLKDYTPEEILYLIDLAAELKDKKKKGIVEQPLIGKNVALIFEKTSTRTRC
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEE
SFEVAAHDLGMGVTYLDPTGSQIGKKESIADTARVLCTMFEGIEYRGFGQEIVEDLAKYS
EHEEHHHHHCCCEEEECCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
SVPVWNGLTNEYHPTQMLADMLTIKEKLGRLKGVKFVYMGDARYNMGNSLMIVCAKLGLH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCC
YTACTAKEYFPDKELVAQCEEWAKISGGSVTLTEDVKAGTKDADVLYTDVWVSMGEPDEV
EEEECHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCHHH
WAERIKALLPYQVNKAVMDNASKDAIFMHCLPAFHDLKTKIGKEIHDKFGLDEMEVTDEV
HHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FESEQSVVFDEAENRMHTIKAVMAATLGAYK
HCCCCCEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLKGRDFLTLKDYTPEEILYLIDLAAELKDKKKKGIVEQPLIGKNVALIFEKTSTRTRC
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEE
SFEVAAHDLGMGVTYLDPTGSQIGKKESIADTARVLCTMFEGIEYRGFGQEIVEDLAKYS
EHEEHHHHHCCCEEEECCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
SVPVWNGLTNEYHPTQMLADMLTIKEKLGRLKGVKFVYMGDARYNMGNSLMIVCAKLGLH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCC
YTACTAKEYFPDKELVAQCEEWAKISGGSVTLTEDVKAGTKDADVLYTDVWVSMGEPDEV
EEEECHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCHHH
WAERIKALLPYQVNKAVMDNASKDAIFMHCLPAFHDLKTKIGKEIHDKFGLDEMEVTDEV
HHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FESEQSVVFDEAENRMHTIKAVMAATLGAYK
HCCCCCEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA