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The map label for this gene is obgE [H]

Identifier: 238896690

GI number: 238896690

Start: 4670599

End: 4671777

Strand: Reverse

Name: obgE [H]

Synonym: KP1_4902

Alternate gene names: 238896690

Gene position: 4671777-4670599 (Counterclockwise)

Preceding gene: 238896691

Following gene: 238896688

Centisome position: 89.01

GC content: 57.17

Gene sequence:

>1179_bases
ATGAAGTTTGTAGATGAAGCAACGATCCTGGTCGTAGCAGGTGACGGCGGCAATGGTTGCGTAAGCTTCCGCCGCGAAAA
GTATATTCCGAAAGGCGGTCCGGATGGCGGCGATGGCGGCGATGGCGGCGATGTCTGGCTGGAAGCGGACGAGAACCTGA
ACACCCTGATCGACTACCGTTTTGAAAAATCGTTCCGCGCCGAACGTGGGCAGAATGGTCAAAGCCGCGACTGTACCGGT
AAGCGCGGTAAAGACGTGACGGTAAAAGTGCCGGTCGGCACCCGGGTTATCGATCAGGGCACTGGCGAGACCATGGGCGA
TATGACCAAACACGGTCAGCGTCTGATGGTGGCGAAAGGCGGCTGGCACGGTTTGGGCAACACCCGTTTCAAATCGTCCG
TTAACCGTACGCCGCGTCAGAAAACCATGGGTACCCCGGGTGATAAACGCGACCTGCAGCTGGAGCTGATGCTGTTGGCC
GATGTCGGGATGCTGGGGATGCCGAACGCCGGCAAATCCACCTTCATCCGTGCGGTCTCCGCCGCCAAGCCGAAAGTGGC
TGACTATCCGTTTACCACCCTGGTGCCAAGCCTGGGCGTGGTGCGTATGGACAATGAAAAGAGCTTCGTAGTTGCCGATA
TCCCGGGGCTGATTGAAGGCGCAGCGGAAGGGGCAGGCCTCGGTATCCGCTTCCTCAAGCACCTCGAGCGCTGCCGCGTA
CTGCTGCACCTCATCGATATCGATCCGATCGACGGCTCCGATCCGGTTGAGAATGCGCGCATTATCATCGGCGAGCTGGA
GAAATACAGCGAGAAGCTAGCCTCCAAACCACGCTGGTTAGTTTTCAACAAGATTGACCTGATGGACAAGGCCGAAGCCG
AAGCCAAAGCCAAAGCGATTGCCGAAGCGCTGGGTTGGGAAGAGAAATTCTACCTGATCTCCGCGGCCAGCCAGCAGGGC
GTGAAAGAGCTGTGCTGGGACGTGATGACCTTCATCATCGAAAACCCGATCGTGCAGGCGGAAGAAGAGCAGAAGCCGGA
TAAAGTCGAGTTTATGTGGGACGACTATCACCGTCAGCAGCTTGAAGAGGCCGAAGCCGAAGCAGAAGATGACGAAGACT
GGGATGACGACTGGGATGAGGACGACGAAGAAGGCGTCGAATTCATCTACAAACGCTAA

Upstream 100 bases:

>100_bases
GATGTATTCCGCCATCGGTCATCGTCTTTGGGGACGTTGGCGTAAGCGAGAGGCGGTAGTACCGCTGCCCCGCTCAGGCG
AATGATTTACGGAGAGTAAA

Downstream 100 bases:

>100_bases
TCCTGACTTCTCTGGATCAAAAAGGGCCGCATCTGATGCGGCCCTTTTGTTTTAATTGTTCTGGTACAAATCTTTATACA
AGCGGCTTTCAAAGCGGACC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKFVDEATILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWLEADENLNTLIDYRFEKSFRAERGQNGQSRDCTG
KRGKDVTVKVPVGTRVIDQGTGETMGDMTKHGQRLMVAKGGWHGLGNTRFKSSVNRTPRQKTMGTPGDKRDLQLELMLLA
DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRV
LLHLIDIDPIDGSDPVENARIIIGELEKYSEKLASKPRWLVFNKIDLMDKAEAEAKAKAIAEALGWEEKFYLISAASQQG
VKELCWDVMTFIIENPIVQAEEEQKPDKVEFMWDDYHRQQLEEAEAEAEDDEDWDDDWDEDDEEGVEFIYKR

Sequences:

>Translated_392_residues
MKFVDEATILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWLEADENLNTLIDYRFEKSFRAERGQNGQSRDCTG
KRGKDVTVKVPVGTRVIDQGTGETMGDMTKHGQRLMVAKGGWHGLGNTRFKSSVNRTPRQKTMGTPGDKRDLQLELMLLA
DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRV
LLHLIDIDPIDGSDPVENARIIIGELEKYSEKLASKPRWLVFNKIDLMDKAEAEAKAKAIAEALGWEEKFYLISAASQQG
VKELCWDVMTFIIENPIVQAEEEQKPDKVEFMWDDYHRQQLEEAEAEAEDDEDWDDDWDEDDEEGVEFIYKR
>Mature_392_residues
MKFVDEATILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWLEADENLNTLIDYRFEKSFRAERGQNGQSRDCTG
KRGKDVTVKVPVGTRVIDQGTGETMGDMTKHGQRLMVAKGGWHGLGNTRFKSSVNRTPRQKTMGTPGDKRDLQLELMLLA
DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRV
LLHLIDIDPIDGSDPVENARIIIGELEKYSEKLASKPRWLVFNKIDLMDKAEAEAKAKAIAEALGWEEKFYLISAASQQG
VKELCWDVMTFIIENPIVQAEEEQKPDKVEFMWDDYHRQQLEEAEAEAEDDEDWDDDWDEDDEEGVEFIYKR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=322, Percent_Identity=40.3726708074534, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955139, Length=293, Percent_Identity=39.9317406143345, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI111955063, Length=129, Percent_Identity=47.2868217054264, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=35.4330708661417, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=32.5925925925926, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1789574, Length=392, Percent_Identity=91.0714285714286, Blast_Score=655, Evalue=0.0,
Organism=Escherichia coli, GI1787454, Length=128, Percent_Identity=31.25, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=292, Percent_Identity=40.7534246575342, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=320, Percent_Identity=31.25, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.15625, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=32.2033898305085, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=172, Percent_Identity=37.2093023255814, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=32.5396825396825, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20129375, Length=285, Percent_Identity=40.7017543859649, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24585318, Length=311, Percent_Identity=35.3697749196142, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=33.59375, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=33.59375, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=33.59375, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 43564; Mature: 43564

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEATILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWLEADENLNTLIDYR
CCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHH
FEKSFRAERGQNGQSRDCTGKRGKDVTVKVPVGTRVIDQGTGETMGDMTKHGQRLMVAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHCCCEEEEECC
GWHGLGNTRFKSSVNRTPRQKTMGTPGDKRDLQLELMLLADVGMLGMPNAGKSTFIRAVS
CCCCCCCCHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRV
HCCCCCCCCCHHHHHCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHH
LLHLIDIDPIDGSDPVENARIIIGELEKYSEKLASKPRWLVFNKIDLMDKAEAEAKAKAI
HHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
AEALGWEEKFYLISAASQQGVKELCWDVMTFIIENPIVQAEEEQKPDKVEFMWDDYHRQQ
HHHHCCCCEEEEEECCHHCCHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEECHHHHHH
LEEAEAEAEDDEDWDDDWDEDDEEGVEFIYKR
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKFVDEATILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWLEADENLNTLIDYR
CCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHH
FEKSFRAERGQNGQSRDCTGKRGKDVTVKVPVGTRVIDQGTGETMGDMTKHGQRLMVAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHCCCEEEEECC
GWHGLGNTRFKSSVNRTPRQKTMGTPGDKRDLQLELMLLADVGMLGMPNAGKSTFIRAVS
CCCCCCCCHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRV
HCCCCCCCCCHHHHHCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHH
LLHLIDIDPIDGSDPVENARIIIGELEKYSEKLASKPRWLVFNKIDLMDKAEAEAKAKAI
HHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
AEALGWEEKFYLISAASQQGVKELCWDVMTFIIENPIVQAEEEQKPDKVEFMWDDYHRQQ
HHHHCCCCEEEEEECCHHCCHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEECHHHHHH
LEEAEAEAEDDEDWDDDWDEDDEEGVEFIYKR
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA