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The map label for this gene is lsrG

Identifier: 238896598

GI number: 238896598

Start: 4579979

End: 4580275

Strand: Reverse

Name: lsrG

Synonym: KP1_4799

Alternate gene names: 238896598

Gene position: 4580275-4579979 (Counterclockwise)

Preceding gene: 238896599

Following gene: 238896595

Centisome position: 87.27

GC content: 55.89

Gene sequence:

>297_bases
ATGAACGTCACGCTAGTGGAGATCAATATTAAACCCGAGCGGGTGGATGAGTTTCTCGAGGTGTTTCGCGCCAACCACGA
GGGCGCGCTGCGGGAGCCAGGCAACCTGCGCTTTGATGTCCTGCAGGATCCCGAGGTGAAAACCCGCTTTTTTATCTACG
AAGCCTATAAAGACGATGAGGCGGTGCTGGCGCATAAGAAGACGCCGCACTATTTAGCCTGCGTCGAAAAGCTGGAGGAG
ATGATGTCGCAGCCGCGGCAGAAGCGCAGCTTTATCGGCCTGTTACCGCAGGTGTGA

Upstream 100 bases:

>100_bases
CGCGCGCGATGCTGAAGGCGGTGAAAAAGGTGGTGCATGAGAATCTGAACGCGCGCGAAGCGTATCAGTTCTGGCAGGAA
GAGAAACAGGGAGAGCTGAA

Downstream 100 bases:

>100_bases
GGGTTATCCTTCACCCTCTCAGAGGGAGAGGGTGAAGGACACTTTATTACGCTTCTTCGACCGAAACGCGCAGGGCCGCC
AGCGCCTTGCGCGCCGCCTT

Product: autoinducer-2 (AI-2) modifying protein LsrG

Products: NA

Alternate protein names: AI-2-degrading protein lsrG

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MNVTLVEINIKPERVDEFLEVFRANHEGALREPGNLRFDVLQDPEVKTRFFIYEAYKDDEAVLAHKKTPHYLACVEKLEE
MMSQPRQKRSFIGLLPQV

Sequences:

>Translated_98_residues
MNVTLVEINIKPERVDEFLEVFRANHEGALREPGNLRFDVLQDPEVKTRFFIYEAYKDDEAVLAHKKTPHYLACVEKLEE
MMSQPRQKRSFIGLLPQV
>Mature_98_residues
MNVTLVEINIKPERVDEFLEVFRANHEGALREPGNLRFDVLQDPEVKTRFFIYEAYKDDEAVLAHKKTPHYLACVEKLEE
MMSQPRQKRSFIGLLPQV

Specific function: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another

COG id: COG1359

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lsrG family

Homologues:

Organism=Escherichia coli, GI1787797, Length=96, Percent_Identity=66.6666666666667, Blast_Score=141, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LSRG_KLEP7 (A6TEB3)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001337164.1
- ProteinModelPortal:   A6TEB3
- SMR:   A6TEB3
- STRING:   A6TEB3
- GeneID:   5341255
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_03502
- eggNOG:   COG1359
- HOGENOM:   HBG693987
- OMA:   KKTPHYL
- ProtClustDB:   PRK10486
- GO:   GO:0005737
- InterPro:   IPR007138
- InterPro:   IPR011008

Pfam domain/function: PF03992 ABM; SSF54909 Dimer_A_B_barrel

EC number: NA

Molecular weight: Translated: 11517; Mature: 11517

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTLVEINIKPERVDEFLEVFRANHEGALREPGNLRFDVLQDPEVKTRFFIYEAYKDDE
CCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCC
AVLAHKKTPHYLACVEKLEEMMSQPRQKRSFIGLLPQV
EEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCC
>Mature Secondary Structure
MNVTLVEINIKPERVDEFLEVFRANHEGALREPGNLRFDVLQDPEVKTRFFIYEAYKDDE
CCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCC
AVLAHKKTPHYLACVEKLEEMMSQPRQKRSFIGLLPQV
EEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA