Click here to switch to the map view.

The map label for this gene is yhcS [C]

Identifier: 238896505

GI number: 238896505

Start: 4485596

End: 4486507

Strand: Reverse

Name: yhcS [C]

Synonym: KP1_4686

Alternate gene names: 238896505

Gene position: 4486507-4485596 (Counterclockwise)

Preceding gene: 238896509

Following gene: 238896502

Centisome position: 85.48

GC content: 66.34

Gene sequence:

>912_bases
ATGGACAAATTACGAGGGATGGAGACGTTTATTGCCGTGGTGGAGTGCGGCAGCTTTACCGGGGCGGCGTCGCGCCTGGG
GCTGTCGGCGGTGATGGTTGGGAAATATATCGCCCAGTTGGAAAGCCAGCTGGCGACGCGTCTGCTGGAGCGTAACACCC
GACGCCAGAGCCTCACCGACGCCGGGCGAGTCTATTTTGACGAAGCGAAACGGGTGATGGAGCAGGTCTCCATCGCCGAA
AGCGCGGTCGAGCGGCTGCGGCTGGCGCCGGCCGGCACCCTGCGGGTGAGCGCTCCCACCTCGTTCGGCGCCAGCGTGAT
CGCGCCCCTGACCGCCACCTTCCTGCAGGCCTGGCCTGCGGTCCGGGTGGAACTGGATCTGACTAACCGGATGGTCGATC
TGGTGGATGAGGGGGTCGATCTGGCGATCCGTATCGGCGAGATCCATCAGGAGGATCTGGTGGCTCGCTACCTGGCGCCG
TATCGGATGGTGATCTGCGCCGCGCCGGCTTATCTGGCGCGTTACGGAACGCCCGGCAGGCCGGAAGATCTCGCCGATCA
TCTCTGTCTGTCCCATACGGTCTGGACCGCCCGCAACGAGTGGCGGCTGCCGGGCGTAGAGGGAGAAGTGCGCTGGAAAC
GCGATGCGGTTTTGCGCTGCAACGATGGCTACGCGCTGCGCCAGGCGGCGATCGCCGGGGCCGGGCTGCTGATGCAGCCG
GAGGTACTGCTGGCCGATGCGCTGGCCAGCGGCAGCCTGGTGCGCGTGCTGGAGGCGTGGACCCCACAGCCGAGACCCGT
GCATCTGCTCTGGCGCCAGGATCGTCGGCCCCTGCCGAAGCTGACGCAGTTTATCGCCCACCTTCAGCAGGGAATGGCCG
ACGCGCTGACAACGACCCGCGCGTCGGAATAA

Upstream 100 bases:

>100_bases
CATGGCAGACTCCTGATGAGGTGAGAGGCTATTTTTTAATAAAAGTAATCTCGGATAAACTGGCTAAAAGTTAGAACATT
ACTAACCAGAGGTTAGCAAT

Downstream 100 bases:

>100_bases
TCACTCCGCCCGCAGCGCCTGCTGCCAGTCGGCAATCAGATCGTGAGGATCTTCGATCCCCACCGACAGGCGGATCAGCT
GCGGTGTGATACCGTTCGCC

Product: putative transcription regulator protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDKLRGMETFIAVVECGSFTGAASRLGLSAVMVGKYIAQLESQLATRLLERNTRRQSLTDAGRVYFDEAKRVMEQVSIAE
SAVERLRLAPAGTLRVSAPTSFGASVIAPLTATFLQAWPAVRVELDLTNRMVDLVDEGVDLAIRIGEIHQEDLVARYLAP
YRMVICAAPAYLARYGTPGRPEDLADHLCLSHTVWTARNEWRLPGVEGEVRWKRDAVLRCNDGYALRQAAIAGAGLLMQP
EVLLADALASGSLVRVLEAWTPQPRPVHLLWRQDRRPLPKLTQFIAHLQQGMADALTTTRASE

Sequences:

>Translated_303_residues
MDKLRGMETFIAVVECGSFTGAASRLGLSAVMVGKYIAQLESQLATRLLERNTRRQSLTDAGRVYFDEAKRVMEQVSIAE
SAVERLRLAPAGTLRVSAPTSFGASVIAPLTATFLQAWPAVRVELDLTNRMVDLVDEGVDLAIRIGEIHQEDLVARYLAP
YRMVICAAPAYLARYGTPGRPEDLADHLCLSHTVWTARNEWRLPGVEGEVRWKRDAVLRCNDGYALRQAAIAGAGLLMQP
EVLLADALASGSLVRVLEAWTPQPRPVHLLWRQDRRPLPKLTQFIAHLQQGMADALTTTRASE
>Mature_303_residues
MDKLRGMETFIAVVECGSFTGAASRLGLSAVMVGKYIAQLESQLATRLLERNTRRQSLTDAGRVYFDEAKRVMEQVSIAE
SAVERLRLAPAGTLRVSAPTSFGASVIAPLTATFLQAWPAVRVELDLTNRMVDLVDEGVDLAIRIGEIHQEDLVARYLAP
YRMVICAAPAYLARYGTPGRPEDLADHLCLSHTVWTARNEWRLPGVEGEVRWKRDAVLRCNDGYALRQAAIAGAGLLMQP
EVLLADALASGSLVRVLEAWTPQPRPVHLLWRQDRRPLPKLTQFIAHLQQGMADALTTTRASE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=280, Percent_Identity=34.2857142857143, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=31.8791946308725, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=31.5972222222222, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1789440, Length=281, Percent_Identity=30.2491103202847, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87081978, Length=264, Percent_Identity=34.0909090909091, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787128, Length=286, Percent_Identity=29.3706293706294, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787589, Length=283, Percent_Identity=28.6219081272085, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789173, Length=260, Percent_Identity=28.0769230769231, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI157672245, Length=154, Percent_Identity=31.1688311688312, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788481, Length=314, Percent_Identity=24.5222929936306, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788706, Length=293, Percent_Identity=24.2320819112628, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=159, Percent_Identity=26.4150943396226, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787879, Length=147, Percent_Identity=29.9319727891156, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786448, Length=265, Percent_Identity=25.6603773584906, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33454; Mature: 33454

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLRGMETFIAVVECGSFTGAASRLGLSAVMVGKYIAQLESQLATRLLERNTRRQSLTD
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRVYFDEAKRVMEQVSIAESAVERLRLAPAGTLRVSAPTSFGASVIAPLTATFLQAWPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCC
VRVELDLTNRMVDLVDEGVDLAIRIGEIHQEDLVARYLAPYRMVICAAPAYLARYGTPGR
EEEEEEHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PEDLADHLCLSHTVWTARNEWRLPGVEGEVRWKRDAVLRCNDGYALRQAAIAGAGLLMQP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEECCCHHHHHHHHHCCCCCCCC
EVLLADALASGSLVRVLEAWTPQPRPVHLLWRQDRRPLPKLTQFIAHLQQGMADALTTTR
HHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
ASE
CCC
>Mature Secondary Structure
MDKLRGMETFIAVVECGSFTGAASRLGLSAVMVGKYIAQLESQLATRLLERNTRRQSLTD
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRVYFDEAKRVMEQVSIAESAVERLRLAPAGTLRVSAPTSFGASVIAPLTATFLQAWPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCC
VRVELDLTNRMVDLVDEGVDLAIRIGEIHQEDLVARYLAPYRMVICAAPAYLARYGTPGR
EEEEEEHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PEDLADHLCLSHTVWTARNEWRLPGVEGEVRWKRDAVLRCNDGYALRQAAIAGAGLLMQP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEECCCHHHHHHHHHCCCCCCCC
EVLLADALASGSLVRVLEAWTPQPRPVHLLWRQDRRPLPKLTQFIAHLQQGMADALTTTR
HHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
ASE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]