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The map label for this gene is epd [H]

Identifier: 238896466

GI number: 238896466

Start: 4445141

End: 4446169

Strand: Reverse

Name: epd [H]

Synonym: KP1_4644

Alternate gene names: 238896466

Gene position: 4446169-4445141 (Counterclockwise)

Preceding gene: 238896467

Following gene: 238896465

Centisome position: 84.71

GC content: 55.98

Gene sequence:

>1029_bases
ATGACCATTCGCATCGCGATTAATGGCTTCGGTCGCATTGGACGCAACGTGGTTCGTGCTCTATATGAATCCGGGCGTCG
TGCGGAAATCACCGTGGTGGCAATCAATGAGCTGGCGGATGCCGCGGGCATCGCGCATTTATTGAAATATGACACCAGCC
ATGGCCGTTTCGCCTGGGATGTCCGTCAGGAGCGCGAGCAGCTGTTTGTTGGCGACGATGCCATCCGTCTGCTGCATGAG
CCGACCATTGCGGCGCTGCCCTGGCGCGAACTGGCGGTGGACGTCGTGCTTGACTGTACCGGGGTATACGGGAGTCGTGA
ACACGGTGAAGCCCATCTTCAGGCGGGGGCGAAAAAAGTGCTCTTTTCCCACCCCGGCGGCAACGACCTCGACGCGACGG
TGGTGTACGGCGTAAATCAGGATGAACTTCGCGCCGGGCATCGCATTGTCTCCAACGCCTCCTGCACCACCAACTGCATT
ATTCCGATCATTAAACTGCTCGATGACGCCTATGGCATTGAGTCCGGCACCGTCACCACCATTCACTCGGCGATGCATGA
CCAGCAGGTGATTGACGCTTATCATCCGGATCTGCGGCGTACCCGCGCGGCCAGCCAGTCGATCATTCCGGTGGATACCA
AACTGGCGGCAGGGATCACCCGTATTTTTCCGCAATTTAACGACCGTTTTGAAGCGATTGCCGTGCGGGTGCCGACGATT
AACGTGACGGCAATTGACCTGAGCGTGACGGTGAAAAAACCGGTAAAAGCATGTGAAGTCAACCAGTTGCTGCAAAAAGC
AGCACAAGGTGCATTTCATGGTATAGTTGACTATACGGAATTACCGTTGGTCTCGACAGATTTTAACCACGATCCGCACA
GCGCCATCGTCGATGGTACGCAAACCCGGGTCAGTGGCGCGCATCTGATCAAAACGCTGGTCTGGTGCGATAACGAATGG
GGCTTTGCTAACCGAATGCTCGACACGACGTTAGCGATGGCGGCTATTGGTTTCAGGTTCGACGCGTAA

Upstream 100 bases:

>100_bases
ATCAATCAGTCGCAGTTTGCAGCTGGTAAGGTTCCCCTCAGAGCGTTGCTGGATTACTCTGTCAGCCACCTCATAACAGG
GACAGCCTTGCAGGAGATCT

Downstream 100 bases:

>100_bases
ACGTCGACAAAACTTTATGAATCAACGAGAGGATTCACCATGTCTGTAATTAAGATGACCGATCTGGATCTGGCTGGTAA
ACGCGTTTTTATCCGTGCGG

Product: erythrose 4-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTIRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGIAHLLKYDTSHGRFAWDVRQEREQLFVGDDAIRLLHE
PTIAALPWRELAVDVVLDCTGVYGSREHGEAHLQAGAKKVLFSHPGGNDLDATVVYGVNQDELRAGHRIVSNASCTTNCI
IPIIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTI
NVTAIDLSVTVKKPVKACEVNQLLQKAAQGAFHGIVDYTELPLVSTDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEW
GFANRMLDTTLAMAAIGFRFDA

Sequences:

>Translated_342_residues
MTIRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGIAHLLKYDTSHGRFAWDVRQEREQLFVGDDAIRLLHE
PTIAALPWRELAVDVVLDCTGVYGSREHGEAHLQAGAKKVLFSHPGGNDLDATVVYGVNQDELRAGHRIVSNASCTTNCI
IPIIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTI
NVTAIDLSVTVKKPVKACEVNQLLQKAAQGAFHGIVDYTELPLVSTDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEW
GFANRMLDTTLAMAAIGFRFDA
>Mature_341_residues
TIRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGIAHLLKYDTSHGRFAWDVRQEREQLFVGDDAIRLLHEP
TIAALPWRELAVDVVLDCTGVYGSREHGEAHLQAGAKKVLFSHPGGNDLDATVVYGVNQDELRAGHRIVSNASCTTNCII
PIIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTIN
VTAIDLSVTVKKPVKACEVNQLLQKAAQGAFHGIVDYTELPLVSTDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWG
FANRMLDTTLAMAAIGFRFDA

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=36.6071428571429, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=36.1702127659575, Blast_Score=221, Evalue=1e-57,
Organism=Escherichia coli, GI1789295, Length=339, Percent_Identity=92.6253687315634, Blast_Score=656, Evalue=0.0,
Organism=Escherichia coli, GI1788079, Length=329, Percent_Identity=41.0334346504559, Blast_Score=254, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=38.3233532934132, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=38.0239520958084, Blast_Score=234, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=37.2372372372372, Blast_Score=224, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=37.2372372372372, Blast_Score=224, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=37.5, Blast_Score=243, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=38.1818181818182, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=37.8048780487805, Blast_Score=239, Evalue=4e-64,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=37.5, Blast_Score=225, Evalue=3e-59,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=37.5, Blast_Score=225, Evalue=3e-59,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=37.1951219512195, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=37.1951219512195, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=35.4545454545455, Blast_Score=221, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 37465; Mature: 37334

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGIAHLLKYDTSHGRFAWD
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEH
VRQEREQLFVGDDAIRLLHEPTIAALPWRELAVDVVLDCTGVYGSREHGEAHLQAGAKKV
HHHHHHHEEECCHHHHHHCCCCEEECCHHHHHHHHEEECCCCCCCCCCCHHHHHCCCCEE
LFSHPGGNDLDATVVYGVNQDELRAGHRIVSNASCTTNCIIPIIKLLDDAYGIESGTVTT
EEECCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHH
IHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTI
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECEE
NVTAIDLSVTVKKPVKACEVNQLLQKAAQGAFHGIVDYTELPLVSTDFNHDPHSAIVDGT
EEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHCCCCHHHCCEEECCCCCCCCCCEECCC
QTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAIGFRFDA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGIAHLLKYDTSHGRFAWD
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEH
VRQEREQLFVGDDAIRLLHEPTIAALPWRELAVDVVLDCTGVYGSREHGEAHLQAGAKKV
HHHHHHHEEECCHHHHHHCCCCEEECCHHHHHHHHEEECCCCCCCCCCCHHHHHCCCCEE
LFSHPGGNDLDATVVYGVNQDELRAGHRIVSNASCTTNCIIPIIKLLDDAYGIESGTVTT
EEECCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHH
IHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTI
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECEE
NVTAIDLSVTVKKPVKACEVNQLLQKAAQGAFHGIVDYTELPLVSTDFNHDPHSAIVDGT
EEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHCCCCHHHCCEEECCCCCCCCCCEECCC
QTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAIGFRFDA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA