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The map label for this gene is yibH [H]

Identifier: 238893535

GI number: 238893535

Start: 1381336

End: 1382478

Strand: Direct

Name: yibH [H]

Synonym: KP1_1438

Alternate gene names: 238893535

Gene position: 1381336-1382478 (Clockwise)

Preceding gene: 238893534

Following gene: 238893540

Centisome position: 26.32

GC content: 61.15

Gene sequence:

>1143_bases
ATGGAAACGTTAATGTTGCTGACCTACGCCGCGCTATGCATCGTGGTGTTTAAAGTTTTTCGCATCCCGCTCAATAAGTG
GACCGTGCCGACGGCGGTGCTCGGCGGTATCGCCCTGATTGGCGCGGTGATCTTCGGGATGAACTACAACTTCCCTTATA
CCGACGTCGGTAACCAGGTGTTTCGCACCGTGCCGATTGTGTCGCAGGTACGCGGCCGGGTGCAGAGCGTACCGGTGAAG
CCTAACCAGATGCTGCATAAGGGCGATGTACTGTTTACCCTCGACCCGACGCCGTTCCAGGCGAAAGTAGACGATCTGCA
GGCGCAGATAAAAGCAGCCAGTCAGGATGCGCTCTCCTTAAACGCGGCGTTAAGCCAGGCGCAGGCCGAGCTGAGCCGTG
CGGTGGCCCAGCGCGACCAGTCGCGGCGGGAGTATGCCCGCTATCGGAAGGGCCATGCCCAGGGCGCCTTCTCCGATCAA
ATGGTTGATACCCGTCTGCAGACGTGGAAAGCCGATGAAGCCAGCGTCAGCGCGGCTCAGGCGAAGGTGGTTCAGGCGCG
TAATGCGCTGGACTCGGTGGTGAAGGGCAAAAACACCACCGTGGCCTCCCTGCTGGCGCAGCTGCAAAAGGCGCAGTTTC
AGCTGGAGAACACCGTCGTCCGCGCCCCGGAGGATGGCTATGTCAGTACCGTCGGCTTACGGCCGGGCACCATGTCCACT
GCGCTGGGGATGATCCCGCTGATGACCTTTGTGCCGGTGGAGGGCGCCGCCTCGCGGGAGTACGTCGCGGCATTTCGCCA
GAACGCCCTGCAGCGTCTGCACAAAGGCGAGCCCGCGGAGCTGATGTTTCCGGCTATCCCGGGCACCGTCTTTCGCGGAG
AAGTGGCCGACGTGCTGCCGGCGATTGGCGAGAGCCAGTTCCAGGGGCAGGGCAAACTGCTGACCACAGACGCGCTCAAT
ACCCATGGCCGGGCGCTGGTGGTGCTGAAGGTGACCGATCCGCGATTTGCCGAATACGCTCTACCGCAGGGGGCTACCCT
CGAGGCGGCGGTCTACTCGGATCATCTGAAAGAGCTGTCGCTGATCAGGAAGATCCTGATCCGCATGAAGAGCTGGGAAA
ACTATATCTATCTCGATCACTAA

Upstream 100 bases:

>100_bases
ACGAGCAGCAGGCGCTGCATCAGCGTCTGGAAACGGTGGTCCAGCAGCTGGAACAGGTCCAGCGCGAGGTGGACGTTCTG
AAAGCGAAGGAGGCAAAATA

Downstream 100 bases:

>100_bases
GCCGGCGGGCGCGGGGCGGACGAACCGCCCCGCGCCGCGGTCAGACCTCGCTGTCCACCAGGCCGTCAATAATCACCTGC
CGCACCCCCTGCGAACAGGG

Product: putative secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
METLMLLTYAALCIVVFKVFRIPLNKWTVPTAVLGGIALIGAVIFGMNYNFPYTDVGNQVFRTVPIVSQVRGRVQSVPVK
PNQMLHKGDVLFTLDPTPFQAKVDDLQAQIKAASQDALSLNAALSQAQAELSRAVAQRDQSRREYARYRKGHAQGAFSDQ
MVDTRLQTWKADEASVSAAQAKVVQARNALDSVVKGKNTTVASLLAQLQKAQFQLENTVVRAPEDGYVSTVGLRPGTMST
ALGMIPLMTFVPVEGAASREYVAAFRQNALQRLHKGEPAELMFPAIPGTVFRGEVADVLPAIGESQFQGQGKLLTTDALN
THGRALVVLKVTDPRFAEYALPQGATLEAAVYSDHLKELSLIRKILIRMKSWENYIYLDH

Sequences:

>Translated_380_residues
METLMLLTYAALCIVVFKVFRIPLNKWTVPTAVLGGIALIGAVIFGMNYNFPYTDVGNQVFRTVPIVSQVRGRVQSVPVK
PNQMLHKGDVLFTLDPTPFQAKVDDLQAQIKAASQDALSLNAALSQAQAELSRAVAQRDQSRREYARYRKGHAQGAFSDQ
MVDTRLQTWKADEASVSAAQAKVVQARNALDSVVKGKNTTVASLLAQLQKAQFQLENTVVRAPEDGYVSTVGLRPGTMST
ALGMIPLMTFVPVEGAASREYVAAFRQNALQRLHKGEPAELMFPAIPGTVFRGEVADVLPAIGESQFQGQGKLLTTDALN
THGRALVVLKVTDPRFAEYALPQGATLEAAVYSDHLKELSLIRKILIRMKSWENYIYLDH
>Mature_380_residues
METLMLLTYAALCIVVFKVFRIPLNKWTVPTAVLGGIALIGAVIFGMNYNFPYTDVGNQVFRTVPIVSQVRGRVQSVPVK
PNQMLHKGDVLFTLDPTPFQAKVDDLQAQIKAASQDALSLNAALSQAQAELSRAVAQRDQSRREYARYRKGHAQGAFSDQ
MVDTRLQTWKADEASVSAAQAKVVQARNALDSVVKGKNTTVASLLAQLQKAQFQLENTVVRAPEDGYVSTVGLRPGTMST
ALGMIPLMTFVPVEGAASREYVAAFRQNALQRLHKGEPAELMFPAIPGTVFRGEVADVLPAIGESQFQGQGKLLTTDALN
THGRALVVLKVTDPRFAEYALPQGATLEAAVYSDHLKELSLIRKILIRMKSWENYIYLDH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790024, Length=382, Percent_Identity=43.1937172774869, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1790012, Length=382, Percent_Identity=42.9319371727749, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI87081951, Length=276, Percent_Identity=27.1739130434783, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790519, Length=260, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41671; Mature: 41671

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLMLLTYAALCIVVFKVFRIPLNKWTVPTAVLGGIALIGAVIFGMNYNFPYTDVGNQV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHH
FRTVPIVSQVRGRVQSVPVKPNQMLHKGDVLFTLDPTPFQAKVDDLQAQIKAASQDALSL
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NAALSQAQAELSRAVAQRDQSRREYARYRKGHAQGAFSDQMVDTRLQTWKADEASVSAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
AKVVQARNALDSVVKGKNTTVASLLAQLQKAQFQLENTVVRAPEDGYVSTVGLRPGTMST
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCCHHHH
ALGMIPLMTFVPVEGAASREYVAAFRQNALQRLHKGEPAELMFPAIPGTVFRGEVADVLP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHH
AIGESQFQGQGKLLTTDALNTHGRALVVLKVTDPRFAEYALPQGATLEAAVYSDHLKELS
HCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCHHHHCCCCCCEEHHHHHHHHHHHHH
LIRKILIRMKSWENYIYLDH
HHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
METLMLLTYAALCIVVFKVFRIPLNKWTVPTAVLGGIALIGAVIFGMNYNFPYTDVGNQV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHH
FRTVPIVSQVRGRVQSVPVKPNQMLHKGDVLFTLDPTPFQAKVDDLQAQIKAASQDALSL
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NAALSQAQAELSRAVAQRDQSRREYARYRKGHAQGAFSDQMVDTRLQTWKADEASVSAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
AKVVQARNALDSVVKGKNTTVASLLAQLQKAQFQLENTVVRAPEDGYVSTVGLRPGTMST
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCCHHHH
ALGMIPLMTFVPVEGAASREYVAAFRQNALQRLHKGEPAELMFPAIPGTVFRGEVADVLP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHH
AIGESQFQGQGKLLTTDALNTHGRALVVLKVTDPRFAEYALPQGATLEAAVYSDHLKELS
HCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCHHHHCCCCCCEEHHHHHHHHHHHHH
LIRKILIRMKSWENYIYLDH
HHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]