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The map label for this gene is tauC [H]

Identifier: 238893295

GI number: 238893295

Start: 1137641

End: 1138468

Strand: Direct

Name: tauC [H]

Synonym: KP1_1172

Alternate gene names: 238893295

Gene position: 1137641-1138468 (Clockwise)

Preceding gene: 238893294

Following gene: 238893296

Centisome position: 21.68

GC content: 65.34

Gene sequence:

>828_bases
ATGAGCGTGGTATTGAACGACAAACCGCGTCAGTCGACGCTGAAGTGGCGCTGGCCGCTCTCCCGTGAGCTCACCCTCAG
CGTGGCGACCCTGGCGGTGCTGCTGGCCGTCTGGTGGGCGGTCGCGGCGTTGCAGCTGATTAGTCCGCTGTTTCTGCCGC
CGCCGGGCCAGGTGCTGCAGAAGCTTATCACCATCGCCGGGCCGCAGGGCTTTATGGATGCGACGCTCTGGCAGCACCTG
GCGGCGAGCCTGACGCGGATCGTTATCGCCCTGCTGGCGGCAGTGCTTATTGGCGTACCGGTGGGGATCGCCATGGGGCT
CAACTCGACGGTGCGCGGGATCCTCGACCCGCTGATCGAACTCTATCGTCCGGTGCCGCCGCTGGCCTACCTACCGCTGA
TGGTGATCTGGTTTGGCATCGGTGAAACCTCGAAGATCCTGCTGATCTACCTGGCGATTTTCGCGCCGGTAGCCATGTCG
GCGCTGGCAGGGGTAAAAAGCGCGCAGCAGGTGCGGATTCGCGCCGCCCGTTCGCTGGGCGCCAGCCGGGCGCAGGTGCT
GTGGCTGGTGATCCTGCCCGGCGCGCTGCCGGAGATCCTCACCGGGCTGCGCATTGGTCTCGGGGTGGGCTGGTCAACGC
TGGTGGCCGCTGAGCTGATCGCCGCCACCCGCGGATTAGGATTTATGGTGCAGTCTGCCGGCGAGTTTCTCGCCACCGAT
GTGGTGCTGGCGGGGATCGCGGTGATTGCCATTATCGCCTTTTTACTGGAACTGGGTCTGCGCGCGCTGCAGCGGCGCCT
GACGCCCTGGCATGGAGAAGTACAATGA

Upstream 100 bases:

>100_bases
TCGCGGGCGAATCCTGCCGCAGCATCAAATCCGACCCGCGCTTTATTGAACAGCGGGAATACATTCTGAGCCGGGTGTTT
GACCAACGGGAGGCTTTCTC

Downstream 100 bases:

>100_bases
GTGAACGTCTGAGCATTACCCCGCTGGGGCCGTATATTGGCGCGCAGGTGAGCGGGGCGGATTTAACCCGTCCGCTGAGC
GACAACCAGTTTGAGCAGCT

Product: taurine transporter subunit

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSVVLNDKPRQSTLKWRWPLSRELTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGPQGFMDATLWQHL
AASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
ALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ

Sequences:

>Translated_275_residues
MSVVLNDKPRQSTLKWRWPLSRELTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGPQGFMDATLWQHL
AASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
ALAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
>Mature_274_residues
SVVLNDKPRQSTLKWRWPLSRELTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQKLITIAGPQGFMDATLWQHLA
ASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSA
LAGVKSAQQVRIRAARSLGASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDV
VLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ

Specific function: Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=275, Percent_Identity=89.4545454545455, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI87081802, Length=238, Percent_Identity=35.2941176470588, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789033, Length=172, Percent_Identity=30.8139534883721, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29426; Mature: 29295

Theoretical pI: Translated: 11.18; Mature: 11.18

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVLNDKPRQSTLKWRWPLSRELTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQ
CCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KLITIAGPQGFMDATLWQHLAASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAARSLG
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
CHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVVLNDKPRQSTLKWRWPLSRELTLSVATLAVLLAVWWAVAALQLISPLFLPPPGQVLQ
CEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KLITIAGPQGFMDATLWQHLAASLTRIVIALLAAVLIGVPVGIAMGLNSTVRGILDPLIE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAARSLG
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASRAQVLWLVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
CHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503 [H]