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The map label for this gene is acoK [H]

Identifier: 238893250

GI number: 238893250

Start: 1093493

End: 1096258

Strand: Direct

Name: acoK [H]

Synonym: KP1_1121

Alternate gene names: 238893250

Gene position: 1093493-1096258 (Clockwise)

Preceding gene: 238893237

Following gene: 238893254

Centisome position: 20.83

GC content: 55.06

Gene sequence:

>2766_bases
ATGAAGCCATTGGATTTAGAAGGTCGCCAATCACCCTCACTGGTCTCCGGGCCATTGCGGCTGACGCGAGGCTTGCCGCT
AATCCTGACCAAATTCGTCCCGCCTCGCTCCTCAATACAATTGCTGGAGCGCCCCCGGCTGCTTCAGCTTCTCAGTCCCG
TTCAGCAGTGCCGGCTGGGCGTCGTCTGCGCCGGCGCTGGATTTGGCAAAACCACGCTGTTGGCGCAATGGCATCAGCAG
ATGGTCGCCCAGGGCGAACGTATTGCCTGGCTGAGCCTCGATGAGGATGATGATGACGTATGGCAGTTTATTCCTTATCT
GCTGCAAGCATTGCGTCCACTCTATGCTGACTGGGACGCCGATTTCTGGCGTGACATGGAAGAACAGAAGCTCTCCAGCT
CCGAGCAACTGCTGGCCGGGCTCATTAACCAGCTACACTACTGCCCGCATGACGTGTACCTGATTATCGACGACTTCCAC
GTGATTAACGATCGTGGGGTCTATGAAGCGCTGGGGTATTTAATCAAGCATGCGCCTGCCGCCTTGCATCTGATCATTGG
CAGCCGTTTCCACCCGAATCTTGCGCTGAGCCAGCTGCAGGCCCAGGACCAACTGGTGGAAATCTATGATCGAGACCTGC
AATTCACGCTCGAAGAAACGAAACACTATTTTAGCCGCACGATTGCGCTACCCCTCAGCAACCACCATGCACAGCGGCTA
CAGTCCGTGACAGAGGGCTGGATCGCAGGGATGAAGATCGCTTCATTGTCGGCAGAATTACAGAATGATCCCGAGCATCT
GTTGCGCAATATGCATGGAGGAACACGGTCCATTGCCCGCTATCTGAAAGAGGTGGTCCTGGATCCGCTGCCGGAAGAGG
TTCTCGATTTCCTGGTGAAAACGTCCTTCCTCAGTCGGTTAAATGCCGAACTATGCAATGCAGTGACTGGACGTGATGAT
AGTAAAGCGATGCTGGCATGGATTGAGCGACACAACCTTTTTTTGTCAGCCCTTGACGAACAAGGCTACTGGTTTCGCTA
CCATCCTCTGTTGCAGGAAAATCTTCGGACCATGCTGCAGCAGAACAACGATATTGACCGCAAACAGCTATATGAATTAG
CCAGTCAGTGGTTCGTCGAACAGAAGCTGTGGTCAGAGGCGGTACGCCATGCGCTCAGCGCAGGCAAGCCGGTGCATAGC
CCCGTGCAGGACGGCGCAAGCGCTCAGTCACTGGCGGAAGAAGGGGATATCGATACCCTGATTTCATGGATGCATCATTT
ACCGCCCAGCACCGATCCGTCGCGCATTGACCTGCAAATTAACCTGGCCTGGGCACTGGCGCATTATTTCCACTTTGATG
AGTCGAGGCAGTTGCTTGATAACCTCGATCAGATGGTACTGCATCATCGCGATGATTTAACCCGCAGCACCTGGTGTAAA
TTGCGCGTTGTGCGGGCAATTTGCGAAGCCTTTGCGGAAAACATCCCGGAGAGTCTGGCTATAGTTCAGCCGTTGCTGGC
CGAAGTGCCCTGCGGCGACACCTGGGTTGATGGTCTGATATGCAATATTCTCAGCTATTGCCATGTTGTTAACCAGCGCT
ATCACGACGCGCTGGAGGTTCAACAGCATATGCCCTCTCCGGAAAGTCCTTTAGATAATCTGTTTGTCTCGGTTTATCGC
GCGTTTATCATTGCCCAGTGCCATCTTTGTCAGGGCGATCTGGGAAAAGCCGGGTGGTACGCAGAGAAAACGTTGCGCCA
GGCTGAATGTTATACCGGTACCCAGTCGACCAGTGGCGCGACGCTGGCGCCGCTGCTGGCGGAGATAGCCTATGAATGTC
AGAGGGGTGACTCGCCCGAGCATCTGTTAGCCGACCGGCTCGAATTCATCGACCGATTCAGTCCACCCGACGCGCTGAGT
CGTTGTTATACCTATCTCGCGCGTCAGGCCTTAGATAACGATATGCCCTATGAGGCCGAGCGATTGCTGGAGCATGCGCA
GCGTCTTGCGGTGTCTCGCGGCTGGCAACGGCTCCAGGCCATGTTGTTAGCCGAGCAGGTGAGGGTGCGACTGCAGCGCG
GCAATTTCACCGGCGCAGAGCAACTGCAGCGACAGCTTGAACAAATGGCCGCCAGCTTCAGAATGGATGCCGAACATCCC
TGCCAACGCGCCATCGTTATGTCTGCATCCCTTAGCCGCAGCCGGCTTCTTCTCGCCACAGGCCAGGCACCGCAAGCCTG
CGTTTTACTGGCTGAGATGGTCTCCGATCAGGAAAGCCGGGGGGACAGGTTAACCGCAGCGCGTCTACGTACGCTCTGGT
CATTGGCCTTGTGGAACAGTGGCAAAACTGCCGCTGCGCGCACGACATTTCAGCCAGTCGTGCAGCTGGCTGAACAACAG
CATCTCAAGGGCCTCTTTCTTGAGGCTGGCGATACCTTGCAACCTTTGCTTGCCGGTATGAATGAATCCTCTTCGGCTTG
TACAGAGAAAAGGGGAGTGCAGGGATCCTGGGCAGACAAGCGCGGGCCTGTAGACGGAACACCGTTTAATAGTGGAAGCC
CCGATATTCCTGGCGAGCTCAGCGAGCGAGAGTTGCAGATATTACAGCTGATCGCTGAAGGTCAGATGAACAAAGAAATC
GCTCGCTCCCTCGCGATTTCTGCCGAGACGGTCAAATGGCACATCAAAAACATCTACGCGAAGCTTAAAGTGAATAGCCG
CACTCAAGCGATGAGCCGGGCGCTGGAGATGAAATTACTGGATTAA

Upstream 100 bases:

>100_bases
CAAACTTTCTAAATTTTGTGTAGCAATAAAGTTTGGCTGCCCCATGTCATCCCGGGGGCTGGCGTACAATTGAAAAAAAC
AAAGCGAGTAGACACCACGG

Downstream 100 bases:

>100_bases
CGGTTTGAACAGGGCGGCCTAGGCGCAAAATATTATAAAGACGAGCCACTTTCTTAACGGGGTTATGAGCCACGGATAAT
CGTGATACTGCTGAGTACAT

Product: trans-acting regulatory protein of aco operon

Products: NA

Alternate protein names: Protein kinase K [H]

Number of amino acids: Translated: 921; Mature: 921

Protein sequence:

>921_residues
MKPLDLEGRQSPSLVSGPLRLTRGLPLILTKFVPPRSSIQLLERPRLLQLLSPVQQCRLGVVCAGAGFGKTTLLAQWHQQ
MVAQGERIAWLSLDEDDDDVWQFIPYLLQALRPLYADWDADFWRDMEEQKLSSSEQLLAGLINQLHYCPHDVYLIIDDFH
VINDRGVYEALGYLIKHAPAALHLIIGSRFHPNLALSQLQAQDQLVEIYDRDLQFTLEETKHYFSRTIALPLSNHHAQRL
QSVTEGWIAGMKIASLSAELQNDPEHLLRNMHGGTRSIARYLKEVVLDPLPEEVLDFLVKTSFLSRLNAELCNAVTGRDD
SKAMLAWIERHNLFLSALDEQGYWFRYHPLLQENLRTMLQQNNDIDRKQLYELASQWFVEQKLWSEAVRHALSAGKPVHS
PVQDGASAQSLAEEGDIDTLISWMHHLPPSTDPSRIDLQINLAWALAHYFHFDESRQLLDNLDQMVLHHRDDLTRSTWCK
LRVVRAICEAFAENIPESLAIVQPLLAEVPCGDTWVDGLICNILSYCHVVNQRYHDALEVQQHMPSPESPLDNLFVSVYR
AFIIAQCHLCQGDLGKAGWYAEKTLRQAECYTGTQSTSGATLAPLLAEIAYECQRGDSPEHLLADRLEFIDRFSPPDALS
RCYTYLARQALDNDMPYEAERLLEHAQRLAVSRGWQRLQAMLLAEQVRVRLQRGNFTGAEQLQRQLEQMAASFRMDAEHP
CQRAIVMSASLSRSRLLLATGQAPQACVLLAEMVSDQESRGDRLTAARLRTLWSLALWNSGKTAAARTTFQPVVQLAEQQ
HLKGLFLEAGDTLQPLLAGMNESSSACTEKRGVQGSWADKRGPVDGTPFNSGSPDIPGELSERELQILQLIAEGQMNKEI
ARSLAISAETVKWHIKNIYAKLKVNSRTQAMSRALEMKLLD

Sequences:

>Translated_921_residues
MKPLDLEGRQSPSLVSGPLRLTRGLPLILTKFVPPRSSIQLLERPRLLQLLSPVQQCRLGVVCAGAGFGKTTLLAQWHQQ
MVAQGERIAWLSLDEDDDDVWQFIPYLLQALRPLYADWDADFWRDMEEQKLSSSEQLLAGLINQLHYCPHDVYLIIDDFH
VINDRGVYEALGYLIKHAPAALHLIIGSRFHPNLALSQLQAQDQLVEIYDRDLQFTLEETKHYFSRTIALPLSNHHAQRL
QSVTEGWIAGMKIASLSAELQNDPEHLLRNMHGGTRSIARYLKEVVLDPLPEEVLDFLVKTSFLSRLNAELCNAVTGRDD
SKAMLAWIERHNLFLSALDEQGYWFRYHPLLQENLRTMLQQNNDIDRKQLYELASQWFVEQKLWSEAVRHALSAGKPVHS
PVQDGASAQSLAEEGDIDTLISWMHHLPPSTDPSRIDLQINLAWALAHYFHFDESRQLLDNLDQMVLHHRDDLTRSTWCK
LRVVRAICEAFAENIPESLAIVQPLLAEVPCGDTWVDGLICNILSYCHVVNQRYHDALEVQQHMPSPESPLDNLFVSVYR
AFIIAQCHLCQGDLGKAGWYAEKTLRQAECYTGTQSTSGATLAPLLAEIAYECQRGDSPEHLLADRLEFIDRFSPPDALS
RCYTYLARQALDNDMPYEAERLLEHAQRLAVSRGWQRLQAMLLAEQVRVRLQRGNFTGAEQLQRQLEQMAASFRMDAEHP
CQRAIVMSASLSRSRLLLATGQAPQACVLLAEMVSDQESRGDRLTAARLRTLWSLALWNSGKTAAARTTFQPVVQLAEQQ
HLKGLFLEAGDTLQPLLAGMNESSSACTEKRGVQGSWADKRGPVDGTPFNSGSPDIPGELSERELQILQLIAEGQMNKEI
ARSLAISAETVKWHIKNIYAKLKVNSRTQAMSRALEMKLLD
>Mature_921_residues
MKPLDLEGRQSPSLVSGPLRLTRGLPLILTKFVPPRSSIQLLERPRLLQLLSPVQQCRLGVVCAGAGFGKTTLLAQWHQQ
MVAQGERIAWLSLDEDDDDVWQFIPYLLQALRPLYADWDADFWRDMEEQKLSSSEQLLAGLINQLHYCPHDVYLIIDDFH
VINDRGVYEALGYLIKHAPAALHLIIGSRFHPNLALSQLQAQDQLVEIYDRDLQFTLEETKHYFSRTIALPLSNHHAQRL
QSVTEGWIAGMKIASLSAELQNDPEHLLRNMHGGTRSIARYLKEVVLDPLPEEVLDFLVKTSFLSRLNAELCNAVTGRDD
SKAMLAWIERHNLFLSALDEQGYWFRYHPLLQENLRTMLQQNNDIDRKQLYELASQWFVEQKLWSEAVRHALSAGKPVHS
PVQDGASAQSLAEEGDIDTLISWMHHLPPSTDPSRIDLQINLAWALAHYFHFDESRQLLDNLDQMVLHHRDDLTRSTWCK
LRVVRAICEAFAENIPESLAIVQPLLAEVPCGDTWVDGLICNILSYCHVVNQRYHDALEVQQHMPSPESPLDNLFVSVYR
AFIIAQCHLCQGDLGKAGWYAEKTLRQAECYTGTQSTSGATLAPLLAEIAYECQRGDSPEHLLADRLEFIDRFSPPDALS
RCYTYLARQALDNDMPYEAERLLEHAQRLAVSRGWQRLQAMLLAEQVRVRLQRGNFTGAEQLQRQLEQMAASFRMDAEHP
CQRAIVMSASLSRSRLLLATGQAPQACVLLAEMVSDQESRGDRLTAARLRTLWSLALWNSGKTAAARTTFQPVVQLAEQQ
HLKGLFLEAGDTLQPLLAGMNESSSACTEKRGVQGSWADKRGPVDGTPFNSGSPDIPGELSERELQILQLIAEGQMNKEI
ARSLAISAETVKWHIKNIYAKLKVNSRTQAMSRALEMKLLD

Specific function: Modulates the activity of transcription regulator virS via phosphorylation [H]

COG id: COG2909

COG function: function code K; ATP-dependent transcriptional regulator

Gene ontology:

Cell location: Cell membrane. Note=Probably attached to cell membrane through interactions mediated by its C- terminal region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Escherichia coli, GI2367223, Length=918, Percent_Identity=25.9259259259259, Blast_Score=213, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR016236
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 104156; Mature: 104156

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLDLEGRQSPSLVSGPLRLTRGLPLILTKFVPPRSSIQLLERPRLLQLLSPVQQCRLG
CCCCCCCCCCCCCHHCCCHHHHCCCHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHCCC
VVCAGAGFGKTTLLAQWHQQMVAQGERIAWLSLDEDDDDVWQFIPYLLQALRPLYADWDA
EEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
DFWRDMEEQKLSSSEQLLAGLINQLHYCPHDVYLIIDDFHVINDRGVYEALGYLIKHAPA
HHHHCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECEEEECCCCHHHHHHHHHHHCCH
ALHLIIGSRFHPNLALSQLQAQDQLVEIYDRDLQFTLEETKHYFSRTIALPLSNHHAQRL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
QSVTEGWIAGMKIASLSAELQNDPEHLLRNMHGGTRSIARYLKEVVLDPLPEEVLDFLVK
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
TSFLSRLNAELCNAVTGRDDSKAMLAWIERHNLFLSALDEQGYWFRYHPLLQENLRTMLQ
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
QNNDIDRKQLYELASQWFVEQKLWSEAVRHALSAGKPVHSPVQDGASAQSLAEEGDIDTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHCCCHHHH
ISWMHHLPPSTDPSRIDLQINLAWALAHYFHFDESRQLLDNLDQMVLHHRDDLTRSTWCK
HHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
LRVVRAICEAFAENIPESLAIVQPLLAEVPCGDTWVDGLICNILSYCHVVNQRYHDALEV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQHMPSPESPLDNLFVSVYRAFIIAQCHLCQGDLGKAGWYAEKTLRQAECYTGTQSTSGA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
TLAPLLAEIAYECQRGDSPEHLLADRLEFIDRFSPPDALSRCYTYLARQALDNDMPYEAE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
RLLEHAQRLAVSRGWQRLQAMLLAEQVRVRLQRGNFTGAEQLQRQLEQMAASFRMDAEHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCH
CQRAIVMSASLSRSRLLLATGQAPQACVLLAEMVSDQESRGDRLTAARLRTLWSLALWNS
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCC
GKTAAARTTFQPVVQLAEQQHLKGLFLEAGDTLQPLLAGMNESSSACTEKRGVQGSWADK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCC
RGPVDGTPFNSGSPDIPGELSERELQILQLIAEGQMNKEIARSLAISAETVKWHIKNIYA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLKVNSRTQAMSRALEMKLLD
HHEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPLDLEGRQSPSLVSGPLRLTRGLPLILTKFVPPRSSIQLLERPRLLQLLSPVQQCRLG
CCCCCCCCCCCCCHHCCCHHHHCCCHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHCCC
VVCAGAGFGKTTLLAQWHQQMVAQGERIAWLSLDEDDDDVWQFIPYLLQALRPLYADWDA
EEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
DFWRDMEEQKLSSSEQLLAGLINQLHYCPHDVYLIIDDFHVINDRGVYEALGYLIKHAPA
HHHHCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECEEEECCCCHHHHHHHHHHHCCH
ALHLIIGSRFHPNLALSQLQAQDQLVEIYDRDLQFTLEETKHYFSRTIALPLSNHHAQRL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
QSVTEGWIAGMKIASLSAELQNDPEHLLRNMHGGTRSIARYLKEVVLDPLPEEVLDFLVK
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
TSFLSRLNAELCNAVTGRDDSKAMLAWIERHNLFLSALDEQGYWFRYHPLLQENLRTMLQ
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
QNNDIDRKQLYELASQWFVEQKLWSEAVRHALSAGKPVHSPVQDGASAQSLAEEGDIDTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHCCCHHHH
ISWMHHLPPSTDPSRIDLQINLAWALAHYFHFDESRQLLDNLDQMVLHHRDDLTRSTWCK
HHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
LRVVRAICEAFAENIPESLAIVQPLLAEVPCGDTWVDGLICNILSYCHVVNQRYHDALEV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQHMPSPESPLDNLFVSVYRAFIIAQCHLCQGDLGKAGWYAEKTLRQAECYTGTQSTSGA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
TLAPLLAEIAYECQRGDSPEHLLADRLEFIDRFSPPDALSRCYTYLARQALDNDMPYEAE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
RLLEHAQRLAVSRGWQRLQAMLLAEQVRVRLQRGNFTGAEQLQRQLEQMAASFRMDAEHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCH
CQRAIVMSASLSRSRLLLATGQAPQACVLLAEMVSDQESRGDRLTAARLRTLWSLALWNS
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCC
GKTAAARTTFQPVVQLAEQQHLKGLFLEAGDTLQPLLAGMNESSSACTEKRGVQGSWADK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCC
RGPVDGTPFNSGSPDIPGELSERELQILQLIAEGQMNKEIARSLAISAETVKWHIKNIYA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLKVNSRTQAMSRALEMKLLD
HHEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]