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The map label for this gene is apaH [H]

Identifier: 238893022

GI number: 238893022

Start: 836106

End: 836954

Strand: Reverse

Name: apaH [H]

Synonym: KP1_0859

Alternate gene names: 238893022

Gene position: 836954-836106 (Counterclockwise)

Preceding gene: 238893023

Following gene: 238893013

Centisome position: 15.95

GC content: 60.66

Gene sequence:

>849_bases
ATGTCAACATACCTTATTGGCGACGTTCACGGTTGCTACGATGAACTGATCGCATTATTAGCGCAGGTTGAATTCGATCC
GCGGAGAGATACGCTGTGGCTGACCGGCGATCTGGTGGCCCGAGGCCCGGGATCGCTGGAGGTCCTGCGCTATGTCAAAT
CTCTGGGCGACAGCGTACGACTGGTGCTGGGCAACCATGACTTACACCTGCTGGCGGTCTTTGCCGGTATCAGCCGCAAC
AAGCCAAAGGATCGTCTGAAATCACTGCTGGAAGCGCCGGATGCCGATGAGCTGCTCAACTGGCTGCGTCGCCAGCCGCT
GCTGCAGGTGGATGAAGAGAAAAAGCTGGTGATGGCCCATGCCGGCATTACGCCGCAGTGGGATCTGGAGACCGCCCAGC
AGTGCGCGCGCGATGTTGAAGCAGTGCTCTCCAGCGACTCCTATCCTTTCTTCCTCGATGCCATGTACGGCGACATGCCG
AACCACTGGAGCAACGAGCTGAGCGGCCTGGCGCGCCTGCGCTTTATCTCTAACGCCTTTACCCGCATGCGCTACTGTTT
CCCGAACGGCCAGCTGGATATGTATTCGAAGGAAGCGCCCGAGGACGCCCCGGCGCCGCTGAAGCCGTGGTTTGCCATTC
CCGGCCCGGTCAGCAATGCCTACAGCATTGCCTTTGGCCACTGGGCTTCGCTGGAGGGACGCGGCACGCCGGAGGGGATT
TACGCCCTGGATACCGGCTGCTGCTGGGGCGGGGAACTCACCTGCCTGCGCTGGGAAGATAAGCAGTACTTCACCCAGCC
GTCAAACCGGCAGAAAAGCCTCGACGAAGGCGAAGCCGTCGCGTCCTGA

Upstream 100 bases:

>100_bases
ATGCAGGGTCATTATGAGATGATCGATATCGACGGCGCGCCGTTCCGTATTGAGATCCCTGTTTTCCGTCTCGCAGTTCC
AACGCTCATTCATTAAAACA

Downstream 100 bases:

>100_bases
CTCTTCCCGGATAGCGGCGCGTTGCGCCTTATCCGGGCTACCTGCGGCGTCGTTTTGTCGGGTGGCGGCTTACGCCTTAC
CCGACCTACGTTTATGTGCT

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRN
KPKDRLKSLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMP
NHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGI
YALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS

Sequences:

>Translated_282_residues
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRN
KPKDRLKSLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMP
NHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGI
YALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>Mature_281_residues
STYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNK
PKDRLKSLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPN
HWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIY
ALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=282, Percent_Identity=88.6524822695035, Blast_Score=523, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31598; Mature: 31467

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVR
CCCEEEECHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEECCCCHHHHHHHHHHCCCCEE
LVLGNHDLHLLAVFAGISRNKPKDRLKSLLEAPDADELLNWLRRQPLLQVDEEKKLVMAH
EEECCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCEEEEEE
AGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHH
TRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGI
HHHHEECCCCCEECCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCEECCCCCCCCCCE
YALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
EEEECCCCCCCCEEEEEECCCHHHCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
STYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVR
CCEEEECHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEECCCCHHHHHHHHHHCCCCEE
LVLGNHDLHLLAVFAGISRNKPKDRLKSLLEAPDADELLNWLRRQPLLQVDEEKKLVMAH
EEECCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCEEEEEE
AGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHH
TRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGI
HHHHEECCCCCEECCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCEECCCCCCCCCCE
YALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
EEEECCCCCCCCEEEEEECCCHHHCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA