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The map label for this gene is holD [H]

Identifier: 238892959

GI number: 238892959

Start: 766805

End: 767218

Strand: Direct

Name: holD [H]

Synonym: KP1_0786

Alternate gene names: 238892959

Gene position: 766805-767218 (Clockwise)

Preceding gene: 238892957

Following gene: 238892960

Centisome position: 14.61

GC content: 63.77

Gene sequence:

>414_bases
ATGACATCCCGACGAGACTGGCAATTACAGCAGCTGGGCATTACCCAGTGGTCGCTGCGCCGACCGGGGGCGTTGCAGGG
CGAAATCGCTATCTCGCTTCCTGAACATATTCGTCTGGTGATGGTGGCGGAAACCCCGCCGTCGCTGACAGAGCCGCTGA
TTGGCGACATATTACGCGCGCTGGCCGTGACGCCAGATCAGGTCCTGCAGCTGACTCCGGAGCGGGTGGCGATGCTGCCG
CAGGACAGCCGCTGCAACAGCTGGCGGTTGGGCACAGAGGCGTCGCTGCCGCTGGCGGGCGCCCAGGTGTCCACCCCCGC
TTTTGATGAACTCCAGACCAGCGCGCCGGCTCGCAGGGCGCTCTGGCAACAAATCTGCGCACATGAACACGATTTCTACC
CTCAGCACGGCTGA

Upstream 100 bases:

>100_bases
AACACTCCTTCATTAAGACTGGCGCCGATTATAGTAGTTTGTTGGCGCAGATACGACGGATTTGCTATATTGCGCGCTTG
TTTAACAGGAGTGTTTCGCT

Downstream 100 bases:

>100_bases
TTTAACCAAAGCCTGGCACATCGAAAAACGCGCCCACGCTTTCCCGTGGAGCGAACAGACTCTGGCCAGTAACCAGGGGG
AGCGCTATTGCAACTATCAG

Product: DNA polymerase III subunit psi

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MTSRRDWQLQQLGITQWSLRRPGALQGEIAISLPEHIRLVMVAETPPSLTEPLIGDILRALAVTPDQVLQLTPERVAMLP
QDSRCNSWRLGTEASLPLAGAQVSTPAFDELQTSAPARRALWQQICAHEHDFYPQHG

Sequences:

>Translated_137_residues
MTSRRDWQLQQLGITQWSLRRPGALQGEIAISLPEHIRLVMVAETPPSLTEPLIGDILRALAVTPDQVLQLTPERVAMLP
QDSRCNSWRLGTEASLPLAGAQVSTPAFDELQTSAPARRALWQQICAHEHDFYPQHG
>Mature_136_residues
TSRRDWQLQQLGITQWSLRRPGALQGEIAISLPEHIRLVMVAETPPSLTEPLIGDILRALAVTPDQVLQLTPERVAMLPQ
DSRCNSWRLGTEASLPLAGAQVSTPAFDELQTSAPARRALWQQICAHEHDFYPQHG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown [H]

COG id: COG3050

COG function: function code L; DNA polymerase III, psi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790831, Length=136, Percent_Identity=71.3235294117647, Blast_Score=207, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004615
- InterPro:   IPR018382
- ProDom:   PD032475 [H]

Pfam domain/function: PF03603 DNA_III_psi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 15268; Mature: 15136

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRRDWQLQQLGITQWSLRRPGALQGEIAISLPEHIRLVMVAETPPSLTEPLIGDILRA
CCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHH
LAVTPDQVLQLTPERVAMLPQDSRCNSWRLGTEASLPLAGAQVSTPAFDELQTSAPARRA
HHCCHHHHHHCCHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHCCCHHHHH
LWQQICAHEHDFYPQHG
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TSRRDWQLQQLGITQWSLRRPGALQGEIAISLPEHIRLVMVAETPPSLTEPLIGDILRA
CCCCCCHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHH
LAVTPDQVLQLTPERVAMLPQDSRCNSWRLGTEASLPLAGAQVSTPAFDELQTSAPARRA
HHCCHHHHHHCCHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHCCCHHHHH
LWQQICAHEHDFYPQHG
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8389364; 8366044; 2828880; 7610040; 9278503; 8505305; 1575709 [H]