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The map label for this gene is dnaC [H]

Identifier: 238892944

GI number: 238892944

Start: 753914

End: 754651

Strand: Reverse

Name: dnaC [H]

Synonym: KP1_0770

Alternate gene names: 238892944

Gene position: 754651-753914 (Counterclockwise)

Preceding gene: 238892945

Following gene: 238892943

Centisome position: 14.38

GC content: 54.47

Gene sequence:

>738_bases
ATGAAAAACGTTGGCGACCTGATGAAACGCCTGCAGAAAATGATGCCGGCACATATTGAACCGGCGTTTAAAACCGGCGA
AGAGCTGCTGGCCTGGCAAAAAGAGCAAGGCCGGCTGCGTTCCGAAGCGCTGGAGCGAGAGAATCGCGCGATGAAAATGC
AGCGCACCTTCAACCGCTCGGGGATCCGCCCGCTGCATCAGAACTGCTCCTTTGATAACTATCGCGTCGAGTGCGAGGGG
CAGATGAATGCGCTCGCCCGGGCGCGCCAGTACGTGGAAGAGTTCGATGGCAATATCGCCAGCTTTATCTTCTCCGGTAA
ACCGGGCACTGGCAAAAACCACCTGGCGGCAGCCATTTGCAACGAGCTGCTGCTGCGCGGGAAATCGGTCTTAATCATCA
CCGTGGCCGATATTATGTCGGCGATGAAAGATACCTTCGGCAACCGGGAAACGAGCGAAGAACAGTTGCTTAACGACCTC
AGCATGGTCGACCTGCTGGTGATCGATGAAATTGGGATGCAGACGGAGTCTCGCTATGAAAAGGTCATTATCAATCAGAT
AGTTGACCGGCGCTCATCCTCCAAACGACCTACCGGGATGCTCACCAACAGCAATATGGAAGAGATGAACAAACTGCTCG
GCGAGCGGGTGATGGACCGTATGCGGCTCGGCAACAGCCTGTGGGTTATCTTCAATTGGGAAAGTTACCGGCACCGCGTT
ACAGGCAAGGAGTATTAA

Upstream 100 bases:

>100_bases
TGCAAATCAGCCGCGCCAGCAACGGCGGACAGCCGAAGCGCGATGTGAACAGCGTTAGCGAACCCGACAGCCATATTCCG
CGAGGTTTCCGAGGATGAGC

Downstream 100 bases:

>100_bases
GAGATTTCCGGGCGACGACGGCGTTATACTAAAGCGATTATTCAGTCACGCTTATGAGTCCGTCTATGAAATCGTTTAAA
AATAGCGTTATTGCCGCGCT

Product: DNA replication protein DnaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKNVGDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRSGIRPLHQNCSFDNYRVECEG
QMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLNDL
SMVDLLVIDEIGMQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRHRV
TGKEY

Sequences:

>Translated_245_residues
MKNVGDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRSGIRPLHQNCSFDNYRVECEG
QMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLNDL
SMVDLLVIDEIGMQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRHRV
TGKEY
>Mature_245_residues
MKNVGDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRSGIRPLHQNCSFDNYRVECEG
QMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLNDL
SMVDLLVIDEIGMQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRHRV
TGKEY

Specific function: This protein is required for chromosomal replication. It forms, in concert with dnaB protein and other prepriming proteins dnaT, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' [H]

COG id: COG1484

COG function: function code L; DNA replication protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaC family [H]

Homologues:

Organism=Escherichia coli, GI1790823, Length=245, Percent_Identity=93.0612244897959, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1787623, Length=243, Percent_Identity=49.7942386831276, Blast_Score=254, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002611 [H]

Pfam domain/function: PF01695 IstB [H]

EC number: NA

Molecular weight: Translated: 28274; Mature: 28274

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVGDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRS
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIRPLHQNCSFDNYRVECEGQMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAIC
CCCHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEHEECCCCCCCHHHHHHHHH
NELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLNDLSMVDLLVIDEIGMQTESRYE
HHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRHRV
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCC
TGKEY
CCCCC
>Mature Secondary Structure
MKNVGDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRS
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIRPLHQNCSFDNYRVECEGQMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAIC
CCCHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEHEECCCCCCCHHHHHHHHH
NELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLNDLSMVDLLVIDEIGMQTESRYE
HHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRHRV
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCC
TGKEY
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]