Click here to switch to the map view.

The map label for this gene is glmS [H]

Identifier: 238892939

GI number: 238892939

Start: 747587

End: 748648

Strand: Direct

Name: glmS [H]

Synonym: KP1_0764

Alternate gene names: 238892939

Gene position: 747587-748648 (Clockwise)

Preceding gene: 238892938

Following gene: 238892940

Centisome position: 14.24

GC content: 58.19

Gene sequence:

>1062_bases
ATGCGACCAACAATGATGACATATATCAGTGAAGAGCCGGCCTGCCTGGCGCAGATCCTGCGCGACTACCGGCAAAAGCT
GGCGCCGATTGAAACCTTCGTCCGCCAGCACCCGGTACGGCGGATATTATTGCTCGCGACCGGATCGTCGCTGAATGCCG
CGCTGTGCGCGCGCTATTTCTTTGAGCAACGCTTCGGTGTGCTGCTTGACATTAAAGAGCCGTACAACTTCACCCATTAC
GACGCGATCGACCCGCATGCCGATCTGGTGGTGGCGATTTCACAGAGCGGAAAAAGCGCGTCGACGCTGGAGGCGATGCG
TAAGGTACAGGCTTCCGGCAAGTCGGTTTTCGCCCTGACCTCAGATCCGCAAAGCCCGATAGGAGGCGCCAGCGATGGCG
TTCTGGATATTAATACCGGGATCGAGAGCGTAGGGTTTGTGACCCGCGGCTTTAGCGCGACGGTGCTCAACCTGTTGCTG
ATAGCGCTGATCATTGCTCGTAAGCAGGAGAAAGCCAGCGAGGTCGAGGAGCAGCACTATCTCGCTGAATTGCAGCGGCT
GGTAGCGGCGATCCCGGAGGTTATCGTCCGCACCTCGCGCTTTATTGACCGCCATAGCGAAACGCTGCGCAGCGGCGAGC
GCTTTGTCGCCACCGGCTACGGCGCGCTGGTTGGCGTGGCGAAGGAGTTCGAAACCAAATTTACCGAGACGGTGCGCGTG
CCTTCCAGCGGCTTTGAGCTGGAAGCCTATATGCATGGCCCCTATCTGGAAGCCAATGCCCGCCATGTGATGCTGTTTAT
TGAAGATACGCCGGACGCGCGAACCCGGGCGCTGCGCGACTATCTGGCGCCGTCCATTGGCCGGGCCTTTACCCTGACGC
TGGGTGACGAAGAGGATGCTCAAACGCTGGCGCTAAACTGTCCGTGCGAGCATCACCTGGCGCCTCTGCTGCTGATTGTC
CCAGTGCAGATGCTCGCCTGGCATACCGCAGGACTGAAAGGCATCGATCTGGCTAAACGTATTTTCGACGATTTTGACCG
CGTCTTAAAAAGTAAAATCTGA

Upstream 100 bases:

>100_bases
GCTACTGGGACGGAAAGTTAAACCGCTCTCAATTATTGGCGGCATGGCGCTGGTGGGCATTCTGGGTTCGTGGATCGGAT
TGTTTTAACGGGAGTGAGCT

Downstream 100 bases:

>100_bases
ATATTCAGGAGAAAACTATGTTGGGTTTTAATCAGGACGAGTACCTGACCAGTGCTCGCGAGATCATCGCTGCGCGTAAA
CAGGCTGAAACCGTAGCCGA

Product: putative glucosamine-fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MRPTMMTYISEEPACLAQILRDYRQKLAPIETFVRQHPVRRILLLATGSSLNAALCARYFFEQRFGVLLDIKEPYNFTHY
DAIDPHADLVVAISQSGKSASTLEAMRKVQASGKSVFALTSDPQSPIGGASDGVLDINTGIESVGFVTRGFSATVLNLLL
IALIIARKQEKASEVEEQHYLAELQRLVAAIPEVIVRTSRFIDRHSETLRSGERFVATGYGALVGVAKEFETKFTETVRV
PSSGFELEAYMHGPYLEANARHVMLFIEDTPDARTRALRDYLAPSIGRAFTLTLGDEEDAQTLALNCPCEHHLAPLLLIV
PVQMLAWHTAGLKGIDLAKRIFDDFDRVLKSKI

Sequences:

>Translated_353_residues
MRPTMMTYISEEPACLAQILRDYRQKLAPIETFVRQHPVRRILLLATGSSLNAALCARYFFEQRFGVLLDIKEPYNFTHY
DAIDPHADLVVAISQSGKSASTLEAMRKVQASGKSVFALTSDPQSPIGGASDGVLDINTGIESVGFVTRGFSATVLNLLL
IALIIARKQEKASEVEEQHYLAELQRLVAAIPEVIVRTSRFIDRHSETLRSGERFVATGYGALVGVAKEFETKFTETVRV
PSSGFELEAYMHGPYLEANARHVMLFIEDTPDARTRALRDYLAPSIGRAFTLTLGDEEDAQTLALNCPCEHHLAPLLLIV
PVQMLAWHTAGLKGIDLAKRIFDDFDRVLKSKI
>Mature_353_residues
MRPTMMTYISEEPACLAQILRDYRQKLAPIETFVRQHPVRRILLLATGSSLNAALCARYFFEQRFGVLLDIKEPYNFTHY
DAIDPHADLVVAISQSGKSASTLEAMRKVQASGKSVFALTSDPQSPIGGASDGVLDINTGIESVGFVTRGFSATVLNLLL
IALIIARKQEKASEVEEQHYLAELQRLVAAIPEVIVRTSRFIDRHSETLRSGERFVATGYGALVGVAKEFETKFTETVRV
PSSGFELEAYMHGPYLEANARHVMLFIEDTPDARTRALRDYLAPSIGRAFTLTLGDEEDAQTLALNCPCEHHLAPLLLIV
PVQMLAWHTAGLKGIDLAKRIFDDFDRVLKSKI

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=369, Percent_Identity=23.0352303523035, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4826742, Length=323, Percent_Identity=22.2910216718266, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1790167, Length=307, Percent_Identity=24.4299674267101, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357745, Length=314, Percent_Identity=22.9299363057325, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 39178; Mature: 39178

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTMMTYISEEPACLAQILRDYRQKLAPIETFVRQHPVRRILLLATGSSLNAALCARYF
CCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHH
FEQRFGVLLDIKEPYNFTHYDAIDPHADLVVAISQSGKSASTLEAMRKVQASGKSVFALT
HHHHCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE
SDPQSPIGGASDGVLDINTGIESVGFVTRGFSATVLNLLLIALIIARKQEKASEVEEQHY
CCCCCCCCCCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAELQRLVAAIPEVIVRTSRFIDRHSETLRSGERFVATGYGALVGVAKEFETKFTETVRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHEEC
PSSGFELEAYMHGPYLEANARHVMLFIEDTPDARTRALRDYLAPSIGRAFTLTLGDEEDA
CCCCCEEEEEECCCEEECCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCC
QTLALNCPCEHHLAPLLLIVPVQMLAWHTAGLKGIDLAKRIFDDFDRVLKSKI
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPTMMTYISEEPACLAQILRDYRQKLAPIETFVRQHPVRRILLLATGSSLNAALCARYF
CCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHH
FEQRFGVLLDIKEPYNFTHYDAIDPHADLVVAISQSGKSASTLEAMRKVQASGKSVFALT
HHHHCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE
SDPQSPIGGASDGVLDINTGIESVGFVTRGFSATVLNLLLIALIIARKQEKASEVEEQHY
CCCCCCCCCCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAELQRLVAAIPEVIVRTSRFIDRHSETLRSGERFVATGYGALVGVAKEFETKFTETVRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHEEC
PSSGFELEAYMHGPYLEANARHVMLFIEDTPDARTRALRDYLAPSIGRAFTLTLGDEEDA
CCCCCEEEEEECCCEEECCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCC
QTLALNCPCEHHLAPLLLIVPVQMLAWHTAGLKGIDLAKRIFDDFDRVLKSKI
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA