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The map label for this gene is hpaD [H]

Identifier: 238892917

GI number: 238892917

Start: 727283

End: 728140

Strand: Reverse

Name: hpaD [H]

Synonym: KP1_0740

Alternate gene names: 238892917

Gene position: 728140-727283 (Counterclockwise)

Preceding gene: 238892918

Following gene: 238892916

Centisome position: 13.87

GC content: 57.11

Gene sequence:

>858_bases
ATGGGTAAATTAGCGTTAGCAGCAAAAATCACTCACGTGCCGTCGATGTATCTGTCTGAGCTGCCGGGGAAAAACCACGG
CTGCCGTCAGGGCGCGATCGACGGGCATAAAGAAATTGGCAAGCGCTGCCGTGAAATGGGCGTCGATACCATCATCGTGT
TTGATACCCACTGGCTGGTCAACAGCGCCTACCACATCAACTGCGCCGACCATTTTCAGGGCGTCTACACCAGTAACGAA
CTGCCGCATTTCATTCGCGACATGACCTACGACTACGACGGCAACCCGGAGCTGGGCAAGCTTATCGCCGACGAGGCGGT
GAAGCTTGGGGTGCGTGCCAAAGCGCACAATATTCCCAGCCTGAAGCTGGAGTACGGCACCCTGGTGCCGATGCGCTACA
TGAACAGCGATAAGCACTTCAAGGTGGTATCTATCTCTGCTTTCTGTACCGTTCACGACTTTGCCGACAGCCGCAGGCTG
GGCGAAGCGATCCTCAAAGCCATTGAGAAATACGACGGCACCGTGGCGGTGCTGGCCAGCGGTTCGCTGTCGCACCGCTT
TATCGACGACCAGCGCGCCGAAGAGGGCATGAACAGCTACACCCGCGAATTTGACCATCAAATGGATGAGCGGGTGGTGA
AGCTGTGGCGCGAGGGCAAATTCAAAGAGTTCTGCACCATGCTGCCGGAGTATGCCGACTACTGCTACGGCGAAGGCAAC
ATGCACGACACGGTGATGCTGCTCGGCCTGCTGGGTTGGGATAAATACGACGGCAAGGTGGAGTTTATCACCGAGCTATT
CGCCAGCTCCGGTACCGGCCAGGTTAACGCCGTGTTCCCGTTGCCAGCGCAGGCGTAA

Upstream 100 bases:

>100_bases
GGCCGCGAAGGCGGCGAGTACAGCTTTGAAGTGTTCGCCGAAATGAAAAACGTCTGCATCTCGATGGGCGACCATCCGAT
CCCGAAATGGGGAGTCTGAT

Downstream 100 bases:

>100_bases
GGGGGCCCCATGCCGCATTTTATCGCCGAATGTACCGACAACATCCGCGAGCAGGCCGATCTGCCTGGGCTGTTCGCCAA
AGTCAACGAGGCGCTGGCCG

Product: 3,4-dihydroxyphenylacetate 2,3-dioxygenase

Products: NA

Alternate protein names: Homoprotocatechuate 2,3-dioxygenase; HPC dioxygenase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MGKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEIGKRCREMGVDTIIVFDTHWLVNSAYHINCADHFQGVYTSNE
LPHFIRDMTYDYDGNPELGKLIADEAVKLGVRAKAHNIPSLKLEYGTLVPMRYMNSDKHFKVVSISAFCTVHDFADSRRL
GEAILKAIEKYDGTVAVLASGSLSHRFIDDQRAEEGMNSYTREFDHQMDERVVKLWREGKFKEFCTMLPEYADYCYGEGN
MHDTVMLLGLLGWDKYDGKVEFITELFASSGTGQVNAVFPLPAQA

Sequences:

>Translated_285_residues
MGKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEIGKRCREMGVDTIIVFDTHWLVNSAYHINCADHFQGVYTSNE
LPHFIRDMTYDYDGNPELGKLIADEAVKLGVRAKAHNIPSLKLEYGTLVPMRYMNSDKHFKVVSISAFCTVHDFADSRRL
GEAILKAIEKYDGTVAVLASGSLSHRFIDDQRAEEGMNSYTREFDHQMDERVVKLWREGKFKEFCTMLPEYADYCYGEGN
MHDTVMLLGLLGWDKYDGKVEFITELFASSGTGQVNAVFPLPAQA
>Mature_284_residues
GKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEIGKRCREMGVDTIIVFDTHWLVNSAYHINCADHFQGVYTSNEL
PHFIRDMTYDYDGNPELGKLIADEAVKLGVRAKAHNIPSLKLEYGTLVPMRYMNSDKHFKVVSISAFCTVHDFADSRRLG
EAILKAIEKYDGTVAVLASGSLSHRFIDDQRAEEGMNSYTREFDHQMDERVVKLWREGKFKEFCTMLPEYADYCYGEGNM
HDTVMLLGLLGWDKYDGKVEFITELFASSGTGQVNAVFPLPAQA

Specific function: Transforms homoprotocatechuic acid (HPC) into 5- carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) [H]

COG id: COG3384

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011984
- InterPro:   IPR004183 [H]

Pfam domain/function: PF02900 LigB [H]

EC number: =1.13.11.15 [H]

Molecular weight: Translated: 32070; Mature: 31939

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEIGKRCREMGVDTIIVFDTHWLV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECHHHH
NSAYHINCADHFQGVYTSNELPHFIRDMTYDYDGNPELGKLIADEAVKLGVRAKAHNIPS
CCEEEEEHHHHHCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCC
LKLEYGTLVPMRYMNSDKHFKVVSISAFCTVHDFADSRRLGEAILKAIEKYDGTVAVLAS
EEEECCCCCCHHHCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GSLSHRFIDDQRAEEGMNSYTREFDHQMDERVVKLWREGKFKEFCTMLPEYADYCYGEGN
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
MHDTVMLLGLLGWDKYDGKVEFITELFASSGTGQVNAVFPLPAQA
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
GKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEIGKRCREMGVDTIIVFDTHWLV
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECHHHH
NSAYHINCADHFQGVYTSNELPHFIRDMTYDYDGNPELGKLIADEAVKLGVRAKAHNIPS
CCEEEEEHHHHHCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCC
LKLEYGTLVPMRYMNSDKHFKVVSISAFCTVHDFADSRRLGEAILKAIEKYDGTVAVLAS
EEEECCCCCCHHHCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GSLSHRFIDDQRAEEGMNSYTREFDHQMDERVVKLWREGKFKEFCTMLPEYADYCYGEGN
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
MHDTVMLLGLLGWDKYDGKVEFITELFASSGTGQVNAVFPLPAQA
CHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2261999 [H]