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The map label for this gene is yjiO [H]

Identifier: 238892898

GI number: 238892898

Start: 707398

End: 708636

Strand: Reverse

Name: yjiO [H]

Synonym: KP1_0719

Alternate gene names: 238892898

Gene position: 708636-707398 (Counterclockwise)

Preceding gene: 238892899

Following gene: 238892897

Centisome position: 13.5

GC content: 62.39

Gene sequence:

>1239_bases
ATGCACAGGATTTCCCACTGGCTGAGCCGACACGCCGCCGCGCTGTTCTTCCCGGCGGCGTTAATTCTGTATGATTTTTC
CGCTTATCTCACTACCGATCTGATCCAGCCGGGGATCCTGCACGTGGTGCGGGATTTCAATGCTGATGTGGCGCTGGCTC
CGGCCTCGGTGAGCCTGTATATGGCCGGCGGCATGGCGCTACAGTGGCTGCTGGGGCCGCTCTCTGACCGGATAGGACGG
CGTCCGGTGCTGCTCACCGGCGCGCTGATTTTCACCCTCGCATGCCTGGCGACCCTGTTCACCACCTCCATGACGCAGTT
CCTGATTGCCCGCTTCGTGCAAGGCACCAGCATCTGCTTTATCGCCACCGTCGGCTACGTCACCGTACAAGAGGCCTTTG
AGGAAAAAAGATCGATCAGACTGATGGCGGTGATCACCTCCGTCGTGCTGGTGGCGCCGATCGTCGGTCCGCTCTCCGGC
GCGGCGCTGATGCATTTCATTCACTGGAAAGCGCTGTTCGGCATTATCGCCGCCATGGGATTGGTGGCCTGGCTCGGCCT
GCTGTTGACCATGCCGGAGACGGTGCGCCGCGGCGATGTGCCGTTCAGCCCCCTGGGCGTGCTGCGCGATTTTCGCAACG
TCTTTCGCAACCGCATCTTTTTACTCGGCGCCGCCACGCTGTCGCTGAGCTATATTCCGCTGATGAGCTGGGTGGCGGTA
TCGCCGGTGATTTTAATGGACGCCGGCGGACTGACCACCAGCGAGTTCGCCTGGAGCCAGGTGCCGGTCTTCAGCGCCGT
TATCATCGCCAACCTGTCGGTGGCGCGCTGGGTAAAAGACCCCACCCGCCCGCGCTTTGTCCTCAGCGCGGTGCCGGTAC
AGATGCTCGGCCTGGCCATCCTGATCGTTGGCAATCTGGTATGGCCCCACGTCTGGCTGTGGTCGGTGGTCGGCACCTGC
TTCTACGCCTTCGGCATCGGGCTGATTTTCCCGACGCTGTTTCGCTTTACCCTCTTTTCCAACGACCTGCCGAAAGGCAC
GGTCTCCGCCTCGCTGAATATCGTGATCCTCAGCGTCAGCGCGTTATCAATTGAAGGCGCGCGCTGGCTGTGGTTCCATG
GCGGCAGACTCCCCTTCCACCTGTTGGCGGTGGCCGCCGGGATTGTCGCCGCCTGCTGCCTGGCCGGACTGTTACGCCAC
CAGCGCGGACAAGCGGTGATCGAAGCCCGGCAGTCGTGA

Upstream 100 bases:

>100_bases
TGCTCTCGCAGATCCCCTCGCTGCTGCATCTGCATATTGGTTAGCAATGATACTATCCGAACAATAGCGCTGATAAATAT
TCCACAGGGAGGGCGAGATG

Downstream 100 bases:

>100_bases
GCCCTTTTACGGAGAAAGCCCCATCATGAATGACATTGAACTCAGCCAGGCGCAGCGCGACCTGCTGCGCGACAAGCTCA
GCAAGTACTGCGCAGAGACC

Product: putative sugar transport protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MHRISHWLSRHAAALFFPAALILYDFSAYLTTDLIQPGILHVVRDFNADVALAPASVSLYMAGGMALQWLLGPLSDRIGR
RPVLLTGALIFTLACLATLFTTSMTQFLIARFVQGTSICFIATVGYVTVQEAFEEKRSIRLMAVITSVVLVAPIVGPLSG
AALMHFIHWKALFGIIAAMGLVAWLGLLLTMPETVRRGDVPFSPLGVLRDFRNVFRNRIFLLGAATLSLSYIPLMSWVAV
SPVILMDAGGLTTSEFAWSQVPVFSAVIIANLSVARWVKDPTRPRFVLSAVPVQMLGLAILIVGNLVWPHVWLWSVVGTC
FYAFGIGLIFPTLFRFTLFSNDLPKGTVSASLNIVILSVSALSIEGARWLWFHGGRLPFHLLAVAAGIVAACCLAGLLRH
QRGQAVIEARQS

Sequences:

>Translated_412_residues
MHRISHWLSRHAAALFFPAALILYDFSAYLTTDLIQPGILHVVRDFNADVALAPASVSLYMAGGMALQWLLGPLSDRIGR
RPVLLTGALIFTLACLATLFTTSMTQFLIARFVQGTSICFIATVGYVTVQEAFEEKRSIRLMAVITSVVLVAPIVGPLSG
AALMHFIHWKALFGIIAAMGLVAWLGLLLTMPETVRRGDVPFSPLGVLRDFRNVFRNRIFLLGAATLSLSYIPLMSWVAV
SPVILMDAGGLTTSEFAWSQVPVFSAVIIANLSVARWVKDPTRPRFVLSAVPVQMLGLAILIVGNLVWPHVWLWSVVGTC
FYAFGIGLIFPTLFRFTLFSNDLPKGTVSASLNIVILSVSALSIEGARWLWFHGGRLPFHLLAVAAGIVAACCLAGLLRH
QRGQAVIEARQS
>Mature_412_residues
MHRISHWLSRHAAALFFPAALILYDFSAYLTTDLIQPGILHVVRDFNADVALAPASVSLYMAGGMALQWLLGPLSDRIGR
RPVLLTGALIFTLACLATLFTTSMTQFLIARFVQGTSICFIATVGYVTVQEAFEEKRSIRLMAVITSVVLVAPIVGPLSG
AALMHFIHWKALFGIIAAMGLVAWLGLLLTMPETVRRGDVPFSPLGVLRDFRNVFRNRIFLLGAATLSLSYIPLMSWVAV
SPVILMDAGGLTTSEFAWSQVPVFSAVIIANLSVARWVKDPTRPRFVLSAVPVQMLGLAILIVGNLVWPHVWLWSVVGTC
FYAFGIGLIFPTLFRFTLFSNDLPKGTVSASLNIVILSVSALSIEGARWLWFHGGRLPFHLLAVAAGIVAACCLAGLLRH
QRGQAVIEARQS

Specific function: Confers resistance to acriflavine, chloramphenicol, norfloxacin, ethidium bromide and TPP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790794, Length=407, Percent_Identity=75.9213759213759, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1787065, Length=377, Percent_Identity=41.9098143236074, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI48994889, Length=221, Percent_Identity=30.7692307692308, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790146, Length=225, Percent_Identity=27.5555555555556, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788509, Length=234, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082312, Length=184, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44883; Mature: 44883

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRISHWLSRHAAALFFPAALILYDFSAYLTTDLIQPGILHVVRDFNADVALAPASVSLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCEEEE
MAGGMALQWLLGPLSDRIGRRPVLLTGALIFTLACLATLFTTSMTQFLIARFVQGTSICF
EECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IATVGYVTVQEAFEEKRSIRLMAVITSVVLVAPIVGPLSGAALMHFIHWKALFGIIAAMG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LVAWLGLLLTMPETVRRGDVPFSPLGVLRDFRNVFRNRIFLLGAATLSLSYIPLMSWVAV
HHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHH
SPVILMDAGGLTTSEFAWSQVPVFSAVIIANLSVARWVKDPTRPRFVLSAVPVQMLGLAI
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LIVGNLVWPHVWLWSVVGTCFYAFGIGLIFPTLFRFTLFSNDLPKGTVSASLNIVILSVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCEEEEEEEEE
ALSIEGARWLWFHGGRLPFHLLAVAAGIVAACCLAGLLRHQRGQAVIEARQS
EEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure
MHRISHWLSRHAAALFFPAALILYDFSAYLTTDLIQPGILHVVRDFNADVALAPASVSLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCEEEE
MAGGMALQWLLGPLSDRIGRRPVLLTGALIFTLACLATLFTTSMTQFLIARFVQGTSICF
EECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IATVGYVTVQEAFEEKRSIRLMAVITSVVLVAPIVGPLSGAALMHFIHWKALFGIIAAMG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LVAWLGLLLTMPETVRRGDVPFSPLGVLRDFRNVFRNRIFLLGAATLSLSYIPLMSWVAV
HHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHH
SPVILMDAGGLTTSEFAWSQVPVFSAVIIANLSVARWVKDPTRPRFVLSAVPVQMLGLAI
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LIVGNLVWPHVWLWSVVGTCFYAFGIGLIFPTLFRFTLFSNDLPKGTVSASLNIVILSVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCEEEEEEEEE
ALSIEGARWLWFHGGRLPFHLLAVAAGIVAACCLAGLLRHQRGQAVIEARQS
EEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]