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The map label for this gene is mlrA [H]

Identifier: 238892864

GI number: 238892864

Start: 667924

End: 668652

Strand: Reverse

Name: mlrA [H]

Synonym: KP1_0683

Alternate gene names: 238892864

Gene position: 668652-667924 (Counterclockwise)

Preceding gene: 238892866

Following gene: 238892862

Centisome position: 12.74

GC content: 62.96

Gene sequence:

>729_bases
ATGCCTTACTCCATCGGCGAATTTGCCCGACTATGCGGGATAAATGCGACCACGCTTCGCGCCTGGCAGCGCCGCTACGG
CCTGCTTAAGCCGCTGCGCACCGATGGAGGACACCGTCTGTACAGCGATGACGACGTCCAGCAGGCGCTGAAGATCCTCG
ACTGGGTGAAAAAAGGGGTGCCGGTCAGCCAGGTGAAACCCCTGCTGTCGCGCCCCGGCGCGCGGCGCACCAATAACTGG
CTGACGCTGCAGGAGACCATGCTGCAGCGGCTGAAAGAGGGAAAAATCGAGTCCCTGCGCCAGCTGATCTACGACGCCGG
GCGCGAATATCCGCGCCAGGAGCTGGTAACCGAAGTGCTGCGTCCGCTGCGCAGCCAGGTCTCCGCCAACGTGCCGGCCA
TCATGACGCTGCGCGAAATTCTCGACGGCATCATCATCGCCTATACCTCGTTTTGCCTCGAAGGCGACAAGAAGGCGCCC
GGGGACAACTTTCTGATCACCGGCTGGCACCTGACCGACGCCTGCGAAATCTGGCTTGAGGCGCTCAAACGTACCGGCCA
GGGCCATCGCATCGACGTTCTGCCGGTGCCTCCCGCCGCCCTGGCGCCGGAGATTTTCCCCCAGCGCAACTGGCTGCTGG
TTACCAGCGGCAAACTTTCTGCCGCCCGCCAGAGGCAGGTCGAACTCTGGCAGCAGCAGGTCGTCTCCCTCGAGATAATT
CCGCTCTAA

Upstream 100 bases:

>100_bases
TACGCGGTTGGGGAAAGTGTAGTGCAAAGCCACTACACTTCACGCCAGCCGTCGTGATTCGTAGTATATTGAGAATATTC
TTTGTTAACAGGTGGCCTCC

Downstream 100 bases:

>100_bases
CCCCCCTGTTTTAACCTACATCCCCTCTCTGAGACGCCAGCGCCCGGTGGCGCGGCGGGCTCACGCTTGCCCTTTGCGCC
ACCCGCGATTTTCACTCCTT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MPYSIGEFARLCGINATTLRAWQRRYGLLKPLRTDGGHRLYSDDDVQQALKILDWVKKGVPVSQVKPLLSRPGARRTNNW
LTLQETMLQRLKEGKIESLRQLIYDAGREYPRQELVTEVLRPLRSQVSANVPAIMTLREILDGIIIAYTSFCLEGDKKAP
GDNFLITGWHLTDACEIWLEALKRTGQGHRIDVLPVPPAALAPEIFPQRNWLLVTSGKLSAARQRQVELWQQQVVSLEII
PL

Sequences:

>Translated_242_residues
MPYSIGEFARLCGINATTLRAWQRRYGLLKPLRTDGGHRLYSDDDVQQALKILDWVKKGVPVSQVKPLLSRPGARRTNNW
LTLQETMLQRLKEGKIESLRQLIYDAGREYPRQELVTEVLRPLRSQVSANVPAIMTLREILDGIIIAYTSFCLEGDKKAP
GDNFLITGWHLTDACEIWLEALKRTGQGHRIDVLPVPPAALAPEIFPQRNWLLVTSGKLSAARQRQVELWQQQVVSLEII
PL
>Mature_241_residues
PYSIGEFARLCGINATTLRAWQRRYGLLKPLRTDGGHRLYSDDDVQQALKILDWVKKGVPVSQVKPLLSRPGARRTNNWL
TLQETMLQRLKEGKIESLRQLIYDAGREYPRQELVTEVLRPLRSQVSANVPAIMTLREILDGIIIAYTSFCLEGDKKAPG
DNFLITGWHLTDACEIWLEALKRTGQGHRIDVLPVPPAALAPEIFPQRNWLLVTSGKLSAARQRQVELWQQQVVSLEIIP
L

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=240, Percent_Identity=44.1666666666667, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1787409, Length=232, Percent_Identity=37.5, Blast_Score=165, Evalue=3e-42,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 27497; Mature: 27366

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYSIGEFARLCGINATTLRAWQRRYGLLKPLRTDGGHRLYSDDDVQQALKILDWVKKGV
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PVSQVKPLLSRPGARRTNNWLTLQETMLQRLKEGKIESLRQLIYDAGREYPRQELVTEVL
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHH
RPLRSQVSANVPAIMTLREILDGIIIAYTSFCLEGDKKAPGDNFLITGWHLTDACEIWLE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHH
ALKRTGQGHRIDVLPVPPAALAPEIFPQRNWLLVTSGKLSAARQRQVELWQQQVVSLEII
HHHHCCCCCEEEEEECCCHHHCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEE
PL
CC
>Mature Secondary Structure 
PYSIGEFARLCGINATTLRAWQRRYGLLKPLRTDGGHRLYSDDDVQQALKILDWVKKGV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PVSQVKPLLSRPGARRTNNWLTLQETMLQRLKEGKIESLRQLIYDAGREYPRQELVTEVL
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHH
RPLRSQVSANVPAIMTLREILDGIIIAYTSFCLEGDKKAPGDNFLITGWHLTDACEIWLE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHH
ALKRTGQGHRIDVLPVPPAALAPEIFPQRNWLLVTSGKLSAARQRQVELWQQQVVSLEII
HHHHCCCCCEEEEEECCCHHHCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEE
PL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 9278503 [H]