Definition Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession NC_012731
Length 5,248,520

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The map label for this gene is xylA [H]

Identifier: 238892852

GI number: 238892852

Start: 657560

End: 658879

Strand: Direct

Name: xylA [H]

Synonym: KP1_0669

Alternate gene names: 238892852

Gene position: 657560-658879 (Clockwise)

Preceding gene: 238892849

Following gene: 238892853

Centisome position: 12.53

GC content: 56.67

Gene sequence:

>1320_bases
ATGCAAACCTATTTCGACCAGGTTGATCGCGTTCGCTTTGCCGGACCCATAACCGATAATCCGCTGGCGTTTCGCCACTA
TAATCCGGATGAAATCGTGCTGGGAAAACGCATGGCCGATCATCTGCGTTTTGCCGCCTGTTACTGGCATAATTTCTGCT
GGAATGGCGCGGATATGTTTGGCGCCGGCTCGTTTGAGCGTCCCTGGCAGGCCGCGGGCGATGCGCTGGAAATGGCCAAA
CGCAAAGCGGACGTGGCGTTTGAATTTTTCTACAAGCTCAACGTGCCGTATTACTGCTTCCACGATGTCGACGTCTCGCC
AGAAGGCGCGTCGCTGAAAGAGTATTTGCATAATTTCGCCGTGATGACCGAGGTACTGGCGGAGAAACAGCAGCAAACCG
GCGTGAAACTGCTGTGGGGCACCGCCAACTGCTTTACCCACCCGCGCTATGGCGCCGGGGCGGCGACCAACCCCGACCCG
GAGGTGTTTGCCTGGGCGGCCACGCAGGTGGTGACCGCCATGAACGCTACCCACCAGCTCGGCGGCGAAAACTATGTGCT
GTGGGGCGGCCGCGAAGGTTACGAGTCCCTGCTGAATACCGATCTGCGCCAGGAGCGCGAGCAGATTGGCCGCTTCCTGC
AGATGGTGGTGGAGCACAAGCATAAGATTGGCTTTGGCGGCACGCTGCTTATCGAGCCGAAACCGCAGGAGCCCACTAAG
CATCAGTACGATTACGATGTCGCGACGGTGTATGGTTTCCTGAAGCAGTTTGGTCTGGAAAATGAGATCAAGGTGAACAT
TGAAGCCAACCACGCCACTCTGGCGGGGCACTCTTTCCACCATGAAATCGCCAGCGCCATCGCGCTGGGCATTTTCGGCT
CCGTTGATGCCAACCGCGGCGATGCGCAGCTCGGCTGGGATACCGATCAGTTCCCGAACAGTATTGAAGAAAATACCCTG
GTGATGTACGAGATCCTCAAAGCCGGGGGATTCACCACCGGTGGCCTGAACTTTGACGCCAAAGTTCGTCGGCAGAGCAC
CGACAAATACGACATGTTCTATGGCCATATTGGCGCCATGGACGTGATGGCGCTGTCCCTCAAGCTGGCCGCGCGCATGA
TTGAGGATGGCAAGCTCGATCAGGGTCTGGCAAAACGCTATGCCGGCTGGCAGGGCGAGCTGGGGCAGAAAATTATGAGC
GGGCAGATGTCGCTGGATAATATTGCCCGATACGCTGAGCAGCATAATCTGAATCCGCAGCCTCAGAGCGGGCGTCAGGA
ATTACTCGAAAATCTCGTCAATACCTATATCTTTGGTTAA

Upstream 100 bases:

>100_bases
TCAATCGCCGAGTGAAATAACGTAATTGAGCAACCGACGATGAGAATACACGATGTGTCACAGTTGTTAATTTTCCTGTT
TCTCAATTTCGGAGTTCATC

Downstream 100 bases:

>100_bases
TTTTTGCTGACATGCCCCCGCGGGGGCATGTATTCCGCCGTCTATCCGCTGCTGGGAAATAGCGTTTATTGGTTCGTGCT
GTGTTTTTTTTGTTAGTCGC

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MQTYFDQVDRVRFAGPITDNPLAFRHYNPDEIVLGKRMADHLRFAACYWHNFCWNGADMFGAGSFERPWQAAGDALEMAK
RKADVAFEFFYKLNVPYYCFHDVDVSPEGASLKEYLHNFAVMTEVLAEKQQQTGVKLLWGTANCFTHPRYGAGAATNPDP
EVFAWAATQVVTAMNATHQLGGENYVLWGGREGYESLLNTDLRQEREQIGRFLQMVVEHKHKIGFGGTLLIEPKPQEPTK
HQYDYDVATVYGFLKQFGLENEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDAQLGWDTDQFPNSIEENTL
VMYEILKAGGFTTGGLNFDAKVRRQSTDKYDMFYGHIGAMDVMALSLKLAARMIEDGKLDQGLAKRYAGWQGELGQKIMS
GQMSLDNIARYAEQHNLNPQPQSGRQELLENLVNTYIFG

Sequences:

>Translated_439_residues
MQTYFDQVDRVRFAGPITDNPLAFRHYNPDEIVLGKRMADHLRFAACYWHNFCWNGADMFGAGSFERPWQAAGDALEMAK
RKADVAFEFFYKLNVPYYCFHDVDVSPEGASLKEYLHNFAVMTEVLAEKQQQTGVKLLWGTANCFTHPRYGAGAATNPDP
EVFAWAATQVVTAMNATHQLGGENYVLWGGREGYESLLNTDLRQEREQIGRFLQMVVEHKHKIGFGGTLLIEPKPQEPTK
HQYDYDVATVYGFLKQFGLENEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDAQLGWDTDQFPNSIEENTL
VMYEILKAGGFTTGGLNFDAKVRRQSTDKYDMFYGHIGAMDVMALSLKLAARMIEDGKLDQGLAKRYAGWQGELGQKIMS
GQMSLDNIARYAEQHNLNPQPQSGRQELLENLVNTYIFG
>Mature_439_residues
MQTYFDQVDRVRFAGPITDNPLAFRHYNPDEIVLGKRMADHLRFAACYWHNFCWNGADMFGAGSFERPWQAAGDALEMAK
RKADVAFEFFYKLNVPYYCFHDVDVSPEGASLKEYLHNFAVMTEVLAEKQQQTGVKLLWGTANCFTHPRYGAGAATNPDP
EVFAWAATQVVTAMNATHQLGGENYVLWGGREGYESLLNTDLRQEREQIGRFLQMVVEHKHKIGFGGTLLIEPKPQEPTK
HQYDYDVATVYGFLKQFGLENEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDAQLGWDTDQFPNSIEENTL
VMYEILKAGGFTTGGLNFDAKVRRQSTDKYDMFYGHIGAMDVMALSLKLAARMIEDGKLDQGLAKRYAGWQGELGQKIMS
GQMSLDNIARYAEQHNLNPQPQSGRQELLENLVNTYIFG

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family [H]

Homologues:

Organism=Escherichia coli, GI1789988, Length=438, Percent_Identity=82.8767123287671, Blast_Score=790, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =5.3.1.5 [H]

Molecular weight: Translated: 49380; Mature: 49380

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTYFDQVDRVRFAGPITDNPLAFRHYNPDEIVLGKRMADHLRFAACYWHNFCWNGADMF
CCCHHHHHHHEEECCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
GAGSFERPWQAAGDALEMAKRKADVAFEFFYKLNVPYYCFHDVDVSPEGASLKEYLHNFA
CCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHH
VMTEVLAEKQQQTGVKLLWGTANCFTHPRYGAGAATNPDPEVFAWAATQVVTAMNATHQL
HHHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHC
GGENYVLWGGREGYESLLNTDLRQEREQIGRFLQMVVEHKHKIGFGGTLLIEPKPQEPTK
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
HQYDYDVATVYGFLKQFGLENEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCCC
DAQLGWDTDQFPNSIEENTLVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDMFYGHIGAM
CCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHH
DVMALSLKLAARMIEDGKLDQGLAKRYAGWQGELGQKIMSGQMSLDNIARYAEQHNLNPQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
PQSGRQELLENLVNTYIFG
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTYFDQVDRVRFAGPITDNPLAFRHYNPDEIVLGKRMADHLRFAACYWHNFCWNGADMF
CCCHHHHHHHEEECCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
GAGSFERPWQAAGDALEMAKRKADVAFEFFYKLNVPYYCFHDVDVSPEGASLKEYLHNFA
CCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHH
VMTEVLAEKQQQTGVKLLWGTANCFTHPRYGAGAATNPDPEVFAWAATQVVTAMNATHQL
HHHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHC
GGENYVLWGGREGYESLLNTDLRQEREQIGRFLQMVVEHKHKIGFGGTLLIEPKPQEPTK
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
HQYDYDVATVYGFLKQFGLENEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCCC
DAQLGWDTDQFPNSIEENTLVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDMFYGHIGAM
CCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHH
DVMALSLKLAARMIEDGKLDQGLAKRYAGWQGELGQKIMSGQMSLDNIARYAEQHNLNPQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
PQSGRQELLENLVNTYIFG
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA