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The map label for this gene is hgiDIIM [H]

Identifier: 238892833

GI number: 238892833

Start: 629818

End: 630870

Strand: Direct

Name: hgiDIIM [H]

Synonym: KP1_0645

Alternate gene names: 238892833

Gene position: 629818-630870 (Clockwise)

Preceding gene: 238892832

Following gene: 238892834

Centisome position: 12.0

GC content: 44.73

Gene sequence:

>1053_bases
ATGAAAAAAGTATCTTGTGTTGATTTATTTTGTGGTGCAGGTGGGTTAACACATGGTCTTGTGCTTGAAGGAGTACCTGT
TGTCGCAGGTATTGATATTGATCCTGCCTGCAAGTTTCCCTATGAGACTAATAATAAAGCAAAATTTATTGAGAAAAGCG
TAAGCGATTTTACATCTTCAGACTTGAATGAGCTCTACGCTGATTCAGATGTAAGGATTCTTGCTGGCTGCGCACCTTGC
CAACCGTTCTCAAGCTATGCAAGGCGTTATGAGCATGGTGGTAAGGATGGTAAGTGGGGGCTGTTGTACGAGTTTTCTCG
CTTGGCTGAGGAAACTCGCCCTGATCTGATCACTATGGAGAATGTACCTTCCGTGGCAAGACATGAAGTTTTCAGCGACT
TTGTCGATACCTTAAAACGTATTGGCTATCACGTTTGGTTTAATGTCATTGATTGCACTCACTATGACGTCCCCCAGATG
CGTAAGCGCATGGTACTGCTTGCTTCTTTACACGGTGAGATAAAACTCGCCGAGTCAACGTGCACTCAGCCAATTACAGT
GAGACAAGCCATAAGCGATCTGCCAGCTTTAAAAGCAGGCGAAACTAGTTCTGGGGATAAGCTACATGTGACTTCAACGT
TGTCGGAAAAAAATCTGCAACGTATTAAAGCTTCAAAACCCGGTGGAACGTGGCGTGACTGGCCTGAACATTTAGTTGCT
GATTGCCATCGTACAGATAGAGGAAAAACATACTCTAGTGTCTATGGTCGAATGGAATGGGATAAACCTGCTCCGACTAT
GACTACTCAGTGTTATGGTTTCGGGAATGGCCGCTTTGGTCACCCAGAGCAAGATCGTGCAATCTCATTGAGAGAAGCTG
CTATTCTTCAGAGTTTTCCGCAGGACTACGTATTTATCCCCGATGATAGCAATGTCAATCTTAGAGTTCTGGGCCGAATG
ATTGGAAATGCAGTTCCGGTAAAGCTGGGTCAGGCAATCGCTCGCAGTATAAATTCACACCTTGACGATTTGAACTTGGT
CGCAACAAAGTGA

Upstream 100 bases:

>100_bases
AAGAGGAATAGTTAGCTTCTTTTTCATTTAAAATATTGTATTTTATGGTTTTTATTGATGTTTATTCATTGGGCCCCCTG
AAGAACGAGATGATTGTCAG

Downstream 100 bases:

>100_bases
AACTTTAACCAGCCTCTGGGCGTACTGAACCGGAATCTGAACATTTTATGGATATTTCGAATCAAAAAAATCATCCTCAA
CAAATTATTCCAGAGCCAGG

Product: putative site-specific DNA methylase

Products: NA

Alternate protein names: M.HgiDII; Cytosine-specific methyltransferase HgiDII [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKVSCVDLFCGAGGLTHGLVLEGVPVVAGIDIDPACKFPYETNNKAKFIEKSVSDFTSSDLNELYADSDVRILAGCAPC
QPFSSYARRYEHGGKDGKWGLLYEFSRLAEETRPDLITMENVPSVARHEVFSDFVDTLKRIGYHVWFNVIDCTHYDVPQM
RKRMVLLASLHGEIKLAESTCTQPITVRQAISDLPALKAGETSSGDKLHVTSTLSEKNLQRIKASKPGGTWRDWPEHLVA
DCHRTDRGKTYSSVYGRMEWDKPAPTMTTQCYGFGNGRFGHPEQDRAISLREAAILQSFPQDYVFIPDDSNVNLRVLGRM
IGNAVPVKLGQAIARSINSHLDDLNLVATK

Sequences:

>Translated_350_residues
MKKVSCVDLFCGAGGLTHGLVLEGVPVVAGIDIDPACKFPYETNNKAKFIEKSVSDFTSSDLNELYADSDVRILAGCAPC
QPFSSYARRYEHGGKDGKWGLLYEFSRLAEETRPDLITMENVPSVARHEVFSDFVDTLKRIGYHVWFNVIDCTHYDVPQM
RKRMVLLASLHGEIKLAESTCTQPITVRQAISDLPALKAGETSSGDKLHVTSTLSEKNLQRIKASKPGGTWRDWPEHLVA
DCHRTDRGKTYSSVYGRMEWDKPAPTMTTQCYGFGNGRFGHPEQDRAISLREAAILQSFPQDYVFIPDDSNVNLRVLGRM
IGNAVPVKLGQAIARSINSHLDDLNLVATK
>Mature_350_residues
MKKVSCVDLFCGAGGLTHGLVLEGVPVVAGIDIDPACKFPYETNNKAKFIEKSVSDFTSSDLNELYADSDVRILAGCAPC
QPFSSYARRYEHGGKDGKWGLLYEFSRLAEETRPDLITMENVPSVARHEVFSDFVDTLKRIGYHVWFNVIDCTHYDVPQM
RKRMVLLASLHGEIKLAESTCTQPITVRQAISDLPALKAGETSSGDKLHVTSTLSEKNLQRIKASKPGGTWRDWPEHLVA
DCHRTDRGKTYSSVYGRMEWDKPAPTMTTQCYGFGNGRFGHPEQDRAISLREAAILQSFPQDYVFIPDDSNVNLRVLGRM
IGNAVPVKLGQAIARSINSHLDDLNLVATK

Specific function: This methylase recognizes the double-stranded sequence GTCGAC, causes specific methylation on C-? on both strands and protects the DNA from cleavage by the HgiDII endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 38899; Mature: 38899

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVSCVDLFCGAGGLTHGLVLEGVPVVAGIDIDPACKFPYETNNKAKFIEKSVSDFTSS
CCCCCEEHHHHCCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DLNELYADSDVRILAGCAPCQPFSSYARRYEHGGKDGKWGLLYEFSRLAEETRPDLITME
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEC
NVPSVARHEVFSDFVDTLKRIGYHVWFNVIDCTHYDVPQMRKRMVLLASLHGEIKLAEST
CCCHHHHHHHHHHHHHHHHHCCHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEECHHH
CTQPITVRQAISDLPALKAGETSSGDKLHVTSTLSEKNLQRIKASKPGGTWRDWPEHLVA
CCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHH
DCHRTDRGKTYSSVYGRMEWDKPAPTMTTQCYGFGNGRFGHPEQDRAISLREAAILQSFP
HHHHCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
QDYVFIPDDSNVNLRVLGRMIGNAVPVKLGQAIARSINSHLDDLNLVATK
CCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MKKVSCVDLFCGAGGLTHGLVLEGVPVVAGIDIDPACKFPYETNNKAKFIEKSVSDFTSS
CCCCCEEHHHHCCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DLNELYADSDVRILAGCAPCQPFSSYARRYEHGGKDGKWGLLYEFSRLAEETRPDLITME
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEC
NVPSVARHEVFSDFVDTLKRIGYHVWFNVIDCTHYDVPQMRKRMVLLASLHGEIKLAEST
CCCHHHHHHHHHHHHHHHHHCCHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEECHHH
CTQPITVRQAISDLPALKAGETSSGDKLHVTSTLSEKNLQRIKASKPGGTWRDWPEHLVA
CCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHH
DCHRTDRGKTYSSVYGRMEWDKPAPTMTTQCYGFGNGRFGHPEQDRAISLREAAILQSFP
HHHHCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
QDYVFIPDDSNVNLRVLGRMIGNAVPVKLGQAIARSINSHLDDLNLVATK
CCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1937045; 7607523 [H]