| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is pcrA [H]
Identifier: 238892774
GI number: 238892774
Start: 570743
End: 572416
Strand: Reverse
Name: pcrA [H]
Synonym: KP1_0577
Alternate gene names: 238892774
Gene position: 572416-570743 (Counterclockwise)
Preceding gene: 238892775
Following gene: 238892773
Centisome position: 10.91
GC content: 37.16
Gene sequence:
>1674_bases ATGACCAGTCAATGGCTACCTTCTGAGGGCATTGAGCCGACACAGGAGTTAATGGATATTATATTCTGTGATCAATCCGT TTCTGTACTTGCTGGCGCGGGGGCGGGTAAAACGGAGCTTTTAGCTCAGAAATCTAATTACTTGTTGCAGACAGGAAAGT GCATGTGGCCTAAACGCATATTATGCCTTTCATATAAAAAAGAGGCGCAAGAGAATATCAAAACACGTGTGATGAAAAGA TGTGGACAAAGAGGTGAGCGCTTTGATTCGTATACTTTCGATGCTTTTTGCAAGAGTATTGTTGACCGTTTTAAAGATGT TTTGCCTGAGAATAAAAGACCCTTAAACAATTATGATTTAGTGTTTAATCAGAAAGCCAATAATGGCAAGGATAAGATAT CATTTGATCTAATAAGGAGTTTGGCATTAGATATTTTAACAATTAGAACGGATATTGTTGATCTTTTTTCGTTGACGTAT TCACATGTTTTTATCGATGAGTTTCAAGATACCCGCTCTGATCAGTATGAAATGATTAAGCTTCTTTTTAAAGACAAAGG AACGCAATTGCTAGCGGTGGGCGATATCAACCAAAGCATTATGTTGTGGGCTGGTGCCAAGAAAACAGTGTTTGAAGATT GTGAAAAAGAGTTTAATACAACCAAAAAACTATTGGTGCATAATTTTAGAGCTAGTGAGGAAATTCAAGAGGTCTTAAGA TGCTTTATTCATTTTGTACAAAATGATGCTAACTTTACGCCAATAATCAAAAGTATCGATAATTGCACTATTCACTATTA TGATAATGAGCTTTCTGAAGCGGATGATATTGCTGATAAAATCGCAAGATTCATCACTTCTGGCATTGAAGAAAAAGAGA TTTGTGTACTGGTTAAACAGCAGTCAGAGCAATATACGGAAAAACTTCGAGATAAGTTAACGACTAAAGGGATTAGAAAT CTTGATTTATCGGAATTGCAAGATGTGTTAAAAGAACCATTAGGGCAAATATTTGCTGCGCTCTTCAAGGTTTATACATC ACGCTCATCATCAAGCTATACCGAGCTTTGTGATTTATATCTTGAGTTGCATCGAGTCTCCCGCGGCGATGAAAAAGAAG ATGCATTAATTAAAGTATTGTCGGATAACATAGCGGAAAATAAGAAAAATTTAGGCGATGAGCCTAGCCCCGATTCATTG ATAACCTGCATTAAGGATATTATAACTCTATTTGGTGTGAAAAGAATGGTGGGGCGATGGAATCAGTATAAGTCCGCTGA TTATTGGGATAAGATCTGGCGTAATCTTGAGCAACATTTGCGCTACACAATAGACGCAACACACTCTCTTAACGAGGCGG CGTTGATGTTTCAGGCGGAAAATTCCGTTCAGGTGATGAACGTGCATAAATGCAAGGGACTGGAATATAAAGTGGTTATT TTTCTTGGCTTAGAGGACCAAGCTTTTTGGGCTTATAAAAACGCAAAATTTGAAAATGATTGCGCTCTCTATGTTGCTTT ATCCAGGGCTAAAGAAAGTATAATAATAACTTCTACAAAATGTAGAGAGCATAGAATCACTAATTGGCGAGATGATAGAA CCTCTACCTATAAAAATATTGGTCCTATATATTCGTTCTTAACGAAACATTGCAAGTTTAGGGAGGTGAGATAA
Upstream 100 bases:
>100_bases TTGAAGAAAAATATACGCCGGATGAAATCAGAGAAAAATTGCCTCCAGTGTTAATTCGGGTAGCTGACAAGACTGTATCG TTATTGGCGGAGGTTATTGA
Downstream 100 bases:
>100_bases TAGAAAGAACTGACGGAAAAAAAATTCAAGTAAATTATCAGGGAATGGGTATGTATAGCCAATAAACTGAAATACTGGCG TATCTTAACCGTTATCAACC
Product: putative helicase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 557; Mature: 556
Protein sequence:
>557_residues MTSQWLPSEGIEPTQELMDIIFCDQSVSVLAGAGAGKTELLAQKSNYLLQTGKCMWPKRILCLSYKKEAQENIKTRVMKR CGQRGERFDSYTFDAFCKSIVDRFKDVLPENKRPLNNYDLVFNQKANNGKDKISFDLIRSLALDILTIRTDIVDLFSLTY SHVFIDEFQDTRSDQYEMIKLLFKDKGTQLLAVGDINQSIMLWAGAKKTVFEDCEKEFNTTKKLLVHNFRASEEIQEVLR CFIHFVQNDANFTPIIKSIDNCTIHYYDNELSEADDIADKIARFITSGIEEKEICVLVKQQSEQYTEKLRDKLTTKGIRN LDLSELQDVLKEPLGQIFAALFKVYTSRSSSSYTELCDLYLELHRVSRGDEKEDALIKVLSDNIAENKKNLGDEPSPDSL ITCIKDIITLFGVKRMVGRWNQYKSADYWDKIWRNLEQHLRYTIDATHSLNEAALMFQAENSVQVMNVHKCKGLEYKVVI FLGLEDQAFWAYKNAKFENDCALYVALSRAKESIIITSTKCREHRITNWRDDRTSTYKNIGPIYSFLTKHCKFREVR
Sequences:
>Translated_557_residues MTSQWLPSEGIEPTQELMDIIFCDQSVSVLAGAGAGKTELLAQKSNYLLQTGKCMWPKRILCLSYKKEAQENIKTRVMKR CGQRGERFDSYTFDAFCKSIVDRFKDVLPENKRPLNNYDLVFNQKANNGKDKISFDLIRSLALDILTIRTDIVDLFSLTY SHVFIDEFQDTRSDQYEMIKLLFKDKGTQLLAVGDINQSIMLWAGAKKTVFEDCEKEFNTTKKLLVHNFRASEEIQEVLR CFIHFVQNDANFTPIIKSIDNCTIHYYDNELSEADDIADKIARFITSGIEEKEICVLVKQQSEQYTEKLRDKLTTKGIRN LDLSELQDVLKEPLGQIFAALFKVYTSRSSSSYTELCDLYLELHRVSRGDEKEDALIKVLSDNIAENKKNLGDEPSPDSL ITCIKDIITLFGVKRMVGRWNQYKSADYWDKIWRNLEQHLRYTIDATHSLNEAALMFQAENSVQVMNVHKCKGLEYKVVI FLGLEDQAFWAYKNAKFENDCALYVALSRAKESIIITSTKCREHRITNWRDDRTSTYKNIGPIYSFLTKHCKFREVR >Mature_556_residues TSQWLPSEGIEPTQELMDIIFCDQSVSVLAGAGAGKTELLAQKSNYLLQTGKCMWPKRILCLSYKKEAQENIKTRVMKRC GQRGERFDSYTFDAFCKSIVDRFKDVLPENKRPLNNYDLVFNQKANNGKDKISFDLIRSLALDILTIRTDIVDLFSLTYS HVFIDEFQDTRSDQYEMIKLLFKDKGTQLLAVGDINQSIMLWAGAKKTVFEDCEKEFNTTKKLLVHNFRASEEIQEVLRC FIHFVQNDANFTPIIKSIDNCTIHYYDNELSEADDIADKIARFITSGIEEKEICVLVKQQSEQYTEKLRDKLTTKGIRNL DLSELQDVLKEPLGQIFAALFKVYTSRSSSSYTELCDLYLELHRVSRGDEKEDALIKVLSDNIAENKKNLGDEPSPDSLI TCIKDIITLFGVKRMVGRWNQYKSADYWDKIWRNLEQHLRYTIDATHSLNEAALMFQAENSVQVMNVHKCKGLEYKVVIF LGLEDQAFWAYKNAKFENDCALYVALSRAKESIIITSTKCREHRITNWRDDRTSTYKNIGPIYSFLTKHCKFREVR
Specific function: DNA helicase used for plasmid rolling-circle replication and also involved in UV repair [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
None
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005751 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 64503; Mature: 64372
Theoretical pI: Translated: 6.82; Mature: 6.82
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.7 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 2.7 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSQWLPSEGIEPTQELMDIIFCDQSVSVLAGAGAGKTELLAQKSNYLLQTGKCMWPKRI CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHCCHHEECCCCCCCHHH LCLSYKKEAQENIKTRVMKRCGQRGERFDSYTFDAFCKSIVDRFKDVLPENKRPLNNYDL HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE VFNQKANNGKDKISFDLIRSLALDILTIRTDIVDLFSLTYSHVFIDEFQDTRSDQYEMIK EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH LLFKDKGTQLLAVGDINQSIMLWAGAKKTVFEDCEKEFNTTKKLLVHNFRASEEIQEVLR HHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH CFIHFVQNDANFTPIIKSIDNCTIHYYDNELSEADDIADKIARFITSGIEEKEICVLVKQ HHHHHHHCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHH QSEQYTEKLRDKLTTKGIRNLDLSELQDVLKEPLGQIFAALFKVYTSRSSSSYTELCDLY HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH LELHRVSRGDEKEDALIKVLSDNIAENKKNLGDEPSPDSLITCIKDIITLFGVKRMVGRW HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCH NQYKSADYWDKIWRNLEQHLRYTIDATHSLNEAALMFQAENSVQVMNVHKCKGLEYKVVI HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCEEEEEEHHCCCCCEEEEE FLGLEDQAFWAYKNAKFENDCALYVALSRAKESIIITSTKCREHRITNWRDDRTSTYKNI EEECCCCEEEEECCCCCCCCCEEEEEEHHCCCEEEEEECCHHHHCCCCCCCCHHHHHHHH GPIYSFLTKHCKFREVR HHHHHHHHHHCCCCCCC >Mature Secondary Structure TSQWLPSEGIEPTQELMDIIFCDQSVSVLAGAGAGKTELLAQKSNYLLQTGKCMWPKRI CCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHCCHHEECCCCCCCHHH LCLSYKKEAQENIKTRVMKRCGQRGERFDSYTFDAFCKSIVDRFKDVLPENKRPLNNYDL HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE VFNQKANNGKDKISFDLIRSLALDILTIRTDIVDLFSLTYSHVFIDEFQDTRSDQYEMIK EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH LLFKDKGTQLLAVGDINQSIMLWAGAKKTVFEDCEKEFNTTKKLLVHNFRASEEIQEVLR HHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH CFIHFVQNDANFTPIIKSIDNCTIHYYDNELSEADDIADKIARFITSGIEEKEICVLVKQ HHHHHHHCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHH QSEQYTEKLRDKLTTKGIRNLDLSELQDVLKEPLGQIFAALFKVYTSRSSSSYTELCDLY HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH LELHRVSRGDEKEDALIKVLSDNIAENKKNLGDEPSPDSLITCIKDIITLFGVKRMVGRW HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCH NQYKSADYWDKIWRNLEQHLRYTIDATHSLNEAALMFQAENSVQVMNVHKCKGLEYKVVI HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCEEEEEEHHCCCCCEEEEE FLGLEDQAFWAYKNAKFENDCALYVALSRAKESIIITSTKCREHRITNWRDDRTSTYKNI EEECCCCEEEEECCCCCCCCCEEEEEEHHCCCEEEEEECCHHHHCCCCCCCCHHHHHHHH GPIYSFLTKHCKFREVR HHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9701819; 9384377 [H]