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The map label for this gene is iolE [H]

Identifier: 238892761

GI number: 238892761

Start: 555795

End: 556694

Strand: Direct

Name: iolE [H]

Synonym: KP1_0564

Alternate gene names: 238892761

Gene position: 555795-556694 (Clockwise)

Preceding gene: 238892760

Following gene: 238892770

Centisome position: 10.59

GC content: 58.33

Gene sequence:

>900_bases
ATGAACAAAGATAACGTCAAACTGGCTATCGCCCCAATCGGCTGGACTAACGATGATATGCCGGAGCTCGGCAGCGAAAA
CACCTTCCAGCAGATCGTCAGCGAAATGGCGCTGGCCGGCTTTACCGGCAGCGAAGTCGGCAGCAAATATCCGCGCGACC
CGGCGGTTCTCAAGCCGATGCTGGATATCCGCGGCATTCAGATCTGCAACGCCTGGTTCAGCACCTTTTTCGCCAACGGC
CAGCGGGAAAAAACCATTGATGAATTCGTCAATCACATGAACTTCCTTCATGCGATGGGCGCGAAAGTGATTGGCTGCTC
CGAGCAGAGCGGCAGCATCCAGGGGCTGGATAAACCGATCCTCGGCGATGCGAAGCCGTGCTTCAGCGACGAAGAGTGGC
AGCGGGTGGCGGAAGGCTACAACACCCTCGGCCGCCTGGCGGCGGAGAAGGGAATGCAGGTCTGTCTGCATCACCACATG
GGCACCGGCATTCAGACCACCGCGGAAATCGACAAATTTATGTCGCTGGTGGACGAGCGCGTCTTCCTGCTGTTCGACAC
CGGACATGCCTGGTATTCCGAAGGCGGCGAAGCGCCGATGCTGGCGATCCTCAAAAAGTATCTGCCGCGCATCAACCACG
TCCATCTGAAGGACGTCCGCCCGCCGGTGATCGACCAGGTGCGCCGTGACGGCCTGTCGTTCCTCGACGGCGTGAAAAAA
GGCACCTTCACCGTCCCGGGCGACGGGGTGATCGATTTCCGTCCGGTGTTCAAGCTGCTGGACGACTTTGGCTATAAAGG
CTGGATGGTAGTGGAAGCCGAGCAGGATCCTGCTCTGGCCAATCCTTTCGAATACGCCGTCAAAGCGCGCAAATATATCC
GCGAAACGGCAGGGATCTAA

Upstream 100 bases:

>100_bases
TTGGCTACCCGGAAAAAATGAAATACCAGGCAGTGGAAACCCGTGAACTTATTGAACGTGAATTGCTGCGCCGCTAAGGC
GCAGCGGCAGGAGCCCTACT

Downstream 100 bases:

>100_bases
TCGTTGTGACATTTTCAGGCCATACCGGGTATGGCCTGCTTTTTTCCTTTCTCAACCGGACCCAGGGCTTAACCACAGCG
CCGGACAGTTCCCTCTCCCT

Product: sugar phosphate isomerases/epimerases

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNKDNVKLAIAPIGWTNDDMPELGSENTFQQIVSEMALAGFTGSEVGSKYPRDPAVLKPMLDIRGIQICNAWFSTFFANG
QREKTIDEFVNHMNFLHAMGAKVIGCSEQSGSIQGLDKPILGDAKPCFSDEEWQRVAEGYNTLGRLAAEKGMQVCLHHHM
GTGIQTTAEIDKFMSLVDERVFLLFDTGHAWYSEGGEAPMLAILKKYLPRINHVHLKDVRPPVIDQVRRDGLSFLDGVKK
GTFTVPGDGVIDFRPVFKLLDDFGYKGWMVVEAEQDPALANPFEYAVKARKYIRETAGI

Sequences:

>Translated_299_residues
MNKDNVKLAIAPIGWTNDDMPELGSENTFQQIVSEMALAGFTGSEVGSKYPRDPAVLKPMLDIRGIQICNAWFSTFFANG
QREKTIDEFVNHMNFLHAMGAKVIGCSEQSGSIQGLDKPILGDAKPCFSDEEWQRVAEGYNTLGRLAAEKGMQVCLHHHM
GTGIQTTAEIDKFMSLVDERVFLLFDTGHAWYSEGGEAPMLAILKKYLPRINHVHLKDVRPPVIDQVRRDGLSFLDGVKK
GTFTVPGDGVIDFRPVFKLLDDFGYKGWMVVEAEQDPALANPFEYAVKARKYIRETAGI
>Mature_299_residues
MNKDNVKLAIAPIGWTNDDMPELGSENTFQQIVSEMALAGFTGSEVGSKYPRDPAVLKPMLDIRGIQICNAWFSTFFANG
QREKTIDEFVNHMNFLHAMGAKVIGCSEQSGSIQGLDKPILGDAKPCFSDEEWQRVAEGYNTLGRLAAEKGMQVCLHHHM
GTGIQTTAEIDKFMSLVDERVFLLFDTGHAWYSEGGEAPMLAILKKYLPRINHVHLKDVRPPVIDQVRRDGLSFLDGVKK
GTFTVPGDGVIDFRPVFKLLDDFGYKGWMVVEAEQDPALANPFEYAVKARKYIRETAGI

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 33317; Mature: 33317

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKDNVKLAIAPIGWTNDDMPELGSENTFQQIVSEMALAGFTGSEVGSKYPRDPAVLKPM
CCCCCEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHH
LDIRGIQICNAWFSTFFANGQREKTIDEFVNHMNFLHAMGAKVIGCSEQSGSIQGLDKPI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCC
LGDAKPCFSDEEWQRVAEGYNTLGRLAAEKGMQVCLHHHMGTGIQTTAEIDKFMSLVDER
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
VFLLFDTGHAWYSEGGEAPMLAILKKYLPRINHVHLKDVRPPVIDQVRRDGLSFLDGVKK
EEEEEECCCHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHCC
GTFTVPGDGVIDFRPVFKLLDDFGYKGWMVVEAEQDPALANPFEYAVKARKYIRETAGI
CCEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKDNVKLAIAPIGWTNDDMPELGSENTFQQIVSEMALAGFTGSEVGSKYPRDPAVLKPM
CCCCCEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHH
LDIRGIQICNAWFSTFFANGQREKTIDEFVNHMNFLHAMGAKVIGCSEQSGSIQGLDKPI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCC
LGDAKPCFSDEEWQRVAEGYNTLGRLAAEKGMQVCLHHHMGTGIQTTAEIDKFMSLVDER
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
VFLLFDTGHAWYSEGGEAPMLAILKKYLPRINHVHLKDVRPPVIDQVRRDGLSFLDGVKK
EEEEEECCCHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHCC
GTFTVPGDGVIDFRPVFKLLDDFGYKGWMVVEAEQDPALANPFEYAVKARKYIRETAGI
CCEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA