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The map label for this gene is iolG [H]

Identifier: 238892759

GI number: 238892759

Start: 553832

End: 554845

Strand: Direct

Name: iolG [H]

Synonym: KP1_0560

Alternate gene names: 238892759

Gene position: 553832-554845 (Clockwise)

Preceding gene: 238892758

Following gene: 238892760

Centisome position: 10.55

GC content: 62.23

Gene sequence:

>1014_bases
ATGTCGCTCAAATTAGGTGTCATCGGCGCTGGCGCTATCGGTAAAGAACACATCCGTCGCTGCACCCAGGTTCTGCAGGG
CGCCACCGTTGTGGCGGTGTCTGATATCAATGCCGACAACGCCCGCGCGGCGGTCGCGCTGCCGGGCGTGCAGGCGGAAG
TCTACGCCGACGGCCACGACGTGATTAACGCCAGCGATGTCGATGCCATCCTGGTCACCTCCTGGGACCCGACCCACGAA
GAGTACACTCTGGCCGCCATCGCCGCCGGTAAGCCGGTATTCTGCGAAAAACCGCTGGCGATGACCGCGGAAGGCTGCCG
CCGCATCGTCGATGCCGAAATGAAGGCCGGCCGTCGTCTGGTGCAGGTTGGCTTTATGCGCCCGTACGACGAAGGCTATC
TGGCGCTGAAAAAAGTGATCGACGATGGCGATATCGGCGCGCCGCTGATGCTGCGCTGCGCCCACCGCAACCAGTCGGTC
GGCGAGAACTACACCACCGATATGGCGATCACCAACACCCTGATCCACGAGCTGGACGTGCTGCGCTGGCTGCTGAACGA
TGACTACCGTTCCGTGCAGGTGCGCTTCCCGCGCTCCACCTCGCACACCCATGCGCGCCTGAAAGATCCGCAGATCGTCT
CCTTTGAAACCAAAAAAGGCACCCTGATCGACGTCGAAGTGTTCGTGAACTGCCAGTACGGGTATGACATCCAGTGCGAA
GTGGTCGGCGAAACCGGGATTGCCCGTCTGCCGGAGCCGTCGGCCGTCCAGATGCGCAAGTCCGCCAGCCTGTCGACCGC
CATTCTCACCGACTGGAAAGACCGCTTTATCAAAGCCTACGACGTCGAGCTGCAGGCCTTTATCAACGACGTCAAAGCCG
GCCAGCTGCACGGCCCGTCGGCCTGGGACGGCTACGCGGCGTCGGTGGCGGCGGACGCCTGCATTAAAGCGCAGGGAACC
AGCGAGCCGGTTGAAGTGACGCTGCCTGAGTGCCCGGCATTCTACAAACGTTAA

Upstream 100 bases:

>100_bases
CGCAAGGTGGCGCAAATGATTAATGAAAAGCGCGCCCAGGCGCGTGATTACTAAAACGAACCTCTACCCTGAATCCTACA
GACTTACGGAGAAAACCATT

Downstream 100 bases:

>100_bases
GCGCGTTTTGCTGACGGAACTTCTTTGCACAGGTAACGACGATGAAAATTGCCTTTGATGTGGATGTGATTAAGGACCTC
GGGATCACCCGCATGGTTCA

Product: putative NADH-dependent dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSLKLGVIGAGAIGKEHIRRCTQVLQGATVVAVSDINADNARAAVALPGVQAEVYADGHDVINASDVDAILVTSWDPTHE
EYTLAAIAAGKPVFCEKPLAMTAEGCRRIVDAEMKAGRRLVQVGFMRPYDEGYLALKKVIDDGDIGAPLMLRCAHRNQSV
GENYTTDMAITNTLIHELDVLRWLLNDDYRSVQVRFPRSTSHTHARLKDPQIVSFETKKGTLIDVEVFVNCQYGYDIQCE
VVGETGIARLPEPSAVQMRKSASLSTAILTDWKDRFIKAYDVELQAFINDVKAGQLHGPSAWDGYAASVAADACIKAQGT
SEPVEVTLPECPAFYKR

Sequences:

>Translated_337_residues
MSLKLGVIGAGAIGKEHIRRCTQVLQGATVVAVSDINADNARAAVALPGVQAEVYADGHDVINASDVDAILVTSWDPTHE
EYTLAAIAAGKPVFCEKPLAMTAEGCRRIVDAEMKAGRRLVQVGFMRPYDEGYLALKKVIDDGDIGAPLMLRCAHRNQSV
GENYTTDMAITNTLIHELDVLRWLLNDDYRSVQVRFPRSTSHTHARLKDPQIVSFETKKGTLIDVEVFVNCQYGYDIQCE
VVGETGIARLPEPSAVQMRKSASLSTAILTDWKDRFIKAYDVELQAFINDVKAGQLHGPSAWDGYAASVAADACIKAQGT
SEPVEVTLPECPAFYKR
>Mature_336_residues
SLKLGVIGAGAIGKEHIRRCTQVLQGATVVAVSDINADNARAAVALPGVQAEVYADGHDVINASDVDAILVTSWDPTHEE
YTLAAIAAGKPVFCEKPLAMTAEGCRRIVDAEMKAGRRLVQVGFMRPYDEGYLALKKVIDDGDIGAPLMLRCAHRNQSVG
ENYTTDMAITNTLIHELDVLRWLLNDDYRSVQVRFPRSTSHTHARLKDPQIVSFETKKGTLIDVEVFVNCQYGYDIQCEV
VGETGIARLPEPSAVQMRKSASLSTAILTDWKDRFIKAYDVELQAFINDVKAGQLHGPSAWDGYAASVAADACIKAQGTS
EPVEVTLPECPAFYKR

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 36782; Mature: 36651

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKLGVIGAGAIGKEHIRRCTQVLQGATVVAVSDINADNARAAVALPGVQAEVYADGHD
CCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCEEEEEECCCC
VINASDVDAILVTSWDPTHEEYTLAAIAAGKPVFCEKPLAMTAEGCRRIVDAEMKAGRRL
EECCCCCCEEEEECCCCCCCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHCCCEE
VQVGFMRPYDEGYLALKKVIDDGDIGAPLMLRCAHRNQSVGENYTTDMAITNTLIHELDV
EEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
LRWLLNDDYRSVQVRFPRSTSHTHARLKDPQIVSFETKKGTLIDVEVFVNCQYGYDIQCE
HHHHHCCCCEEEEEEECCCCCCCEEECCCCEEEEEECCCCCEEEEEEEEEEECCCEEEEE
VVGETGIARLPEPSAVQMRKSASLSTAILTDWKDRFIKAYDVELQAFINDVKAGQLHGPS
EECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHEEEECHHHHHHHHHHCCCCCCCCC
AWDGYAASVAADACIKAQGTSEPVEVTLPECPAFYKR
CCCCHHHHHHHHHHEECCCCCCCEEEECCCCCHHHCC
>Mature Secondary Structure 
SLKLGVIGAGAIGKEHIRRCTQVLQGATVVAVSDINADNARAAVALPGVQAEVYADGHD
CEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCEEEEEECCCC
VINASDVDAILVTSWDPTHEEYTLAAIAAGKPVFCEKPLAMTAEGCRRIVDAEMKAGRRL
EECCCCCCEEEEECCCCCCCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHCCCEE
VQVGFMRPYDEGYLALKKVIDDGDIGAPLMLRCAHRNQSVGENYTTDMAITNTLIHELDV
EEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
LRWLLNDDYRSVQVRFPRSTSHTHARLKDPQIVSFETKKGTLIDVEVFVNCQYGYDIQCE
HHHHHCCCCEEEEEEECCCCCCCEEECCCCEEEEEECCCCCEEEEEEEEEEECCCEEEEE
VVGETGIARLPEPSAVQMRKSASLSTAILTDWKDRFIKAYDVELQAFINDVKAGQLHGPS
EECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHEEEECHHHHHHHHHHCCCCCCCCC
AWDGYAASVAADACIKAQGTSEPVEVTLPECPAFYKR
CCCCHHHHHHHHHHEECCCCCCCEEEECCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA