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The map label for this gene is nrdD [H]

Identifier: 238892730

GI number: 238892730

Start: 514023

End: 516161

Strand: Reverse

Name: nrdD [H]

Synonym: KP1_0525

Alternate gene names: 238892730

Gene position: 516161-514023 (Counterclockwise)

Preceding gene: 238892731

Following gene: 238892729

Centisome position: 9.83

GC content: 59.61

Gene sequence:

>2139_bases
ATGACACCGCATGTGATGAAACGTGATGGCTGTAAAGTGCCGTTCAACTCAGAGCGCATTCAGGAAGCAATTCTGCGTGC
AGCTAAAGCAGCGGGAGTCGATGACGCAGACTATTGCGCCACCGTCGCAGAAGTCGTTAGCCAACAAATGCAGGGCCGCG
CCCAGGTCGACATCAACGAGATCCAGACCGCGGTGGAAAACCAGCTGATGTCCGGCCCCTATAAGCAGCTGGCGCGCGCC
TACATTGAGTATCGCCATGACCGCGATAGCCAGCGTGAGAAGCGCGGCCGCCTCAATCAGGAGATCCGCGGCCTCGTCGA
GCAGACCAACTCCGCGCTGCTCAACGAAAACGCCAACAAGGACAGTAAAGTCATCCCGACCCAGCGCGACCTGCTGGCCG
GGATCGTCGCCAAGCACTACGCCCGGCAGCACCTGCTGCCCCACGATGTGGTGATGGCCCACGAGCGCGGCATGATCCAC
TATCATGACCTCGATTACTCGCCCTTCTTCCCGATGTTCAACTGCATGCTGATCGACCTGAAAGGCATGCTGACCCAGGG
CTTTAAGATGGGCAACGCGGAGATCGAGCCGCCGAAGTCTATCTCTACCGCCACCGCGGTGACAGCGCAGATCATCGCCC
AGGTCGCCAGCCATATTTACGGCGGCACCACCATCAACCGCATCGACGAAGTACTGGCGCCGTTCGTCAGCGAAAGCTTC
AAAAAGCATCGCAAAATCGCCGAAGAGTGGCAGATCCCGGATGCCGAAGGCTATGCCCGCGCCCGTACCGAAAAAGAGTG
CTACGACGCCTTCCAGTCGCTGGAGTATGAGGTTAACACACTGCATACCGCCAACGGCCAGACGCCGTTCGTCACCTTCG
GGTTCGGCCTTGGCACCAGCTGGGAATCGCGGCTGATCCAGCAGTCGATTCTGCGCAACCGCATTGCCGGCCTCGGTAAA
AATCGCAAAACCGCGGTGTTCCCGAAACTGGTGTTCGCGATCCGCGACGGCCTGAACCATAAGTTCGGCGACCCGAACTA
CGACATCAAACAGCTGGCGCTGGAGTGCGCCAGCAAGCGCATGTACCCGGATATCCTCAACTACGATCAGGTGGTGAAAG
TCACCGGGTCGTTTAAAACGCCGATGGGCTGCCGCAGCTTCCTCGGGGTATGGGAAAACGAGAACGGCGAGCAGGTGCAT
GATGGACGCAATAACCTCGGCGTGATCAGTCTCAACCTGCCGCGCATCGCCCTGGAAGCGAAAGGCGATGAAGCCGCCTT
CTGGGCGCTGCTGGACGAGCGCCTGCAGCTGGCGCGTAAAGCGCTGATGACCCGTATCGCCCGCCTGGAAGGAGTGAAGG
CTCGCGTGGCGCCGATCCTGTATATGGAAGGCGCCTGCGGCGTGCGGCTGAAAGCCGACGACGACGTCTCCGAGATCTTC
AAAAACGGCCGCGCGTCCATTTCTCTGGGCTATATCGGTATCCATGAAACCATCAATGCGCTGTACGGCAACCAGCATAT
GTACGACAGCGAGGCGCTGCGTGAGAAAGGCGTGGCCATCGTCCAGCGCCTGCGCGACGCCGTCGATTTGTGGAAGGAAG
AAACCGGCTACGGCTTTAGCCTGTACAGCACGCCGAGCGAAAACCTGTGCGATCGCTTCTGCCGTCTCGACACCGCCGAG
TTTGGCGTGGTGGAAGGGGTAACCGACAAAGGTTACTACACCAACAGCTTCCACCTCGACGTGGAGAAGAAGGTCAACCC
GTACGACAAGATCGATTTCGAAGCGCCGTACCCGCCGCTGGCCAACGGGGGGTTCATTTGCTACGGCGAGTACCCGAATA
TCCAGCATAACCTCAAGGCGCTGGAAGACGTGTGGGATTACAGCTATCAGCACGTGCCGTACTACGGGACCAATACGCCG
ATCGATGAGTGCTACGAGTGCGGTTTTACCGGCGAGTTCGAGTGCACCAGCAAGGGCTTTACCTGCCCGAAATGCGGTAA
CCACGACGCCGCCCGCGTTTCCGTTACCCGCCGGGTGTGCGGTTATCTCGGCAGCCCGGACGCGCGGCCGTTCAACGCCG
GCAAGCAGGAAGAAGTGAAGCGCCGCGTGAAGCACCTGGGCAATGGGCAGATTGGTTAA

Upstream 100 bases:

>100_bases
ACGGGCCGGATCCGAAGGTAAACAGCACGAGCCGTAGCGTGCAGCGCCTTCGGGATAACCTCCGCCTCTGTGGATAACCT
GTTCTATATATGGAGTGATC

Downstream 100 bases:

>100_bases
TTCCAGCTGGTTTAGCCCCTCACCCTCTCCCCAACGGGGAGAAGGGACCGGCCCCGTAGCCGTTTGGCCACTAAGGAGCC
GTTCCCGGATCGCGGCGCAA

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MTPHVMKRDGCKVPFNSERIQEAILRAAKAAGVDDADYCATVAEVVSQQMQGRAQVDINEIQTAVENQLMSGPYKQLARA
YIEYRHDRDSQREKRGRLNQEIRGLVEQTNSALLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPHDVVMAHERGMIH
YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVSESF
KKHRKIAEEWQIPDAEGYARARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWESRLIQQSILRNRIAGLGK
NRKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQVH
DGRNNLGVISLNLPRIALEAKGDEAAFWALLDERLQLARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIF
KNGRASISLGYIGIHETINALYGNQHMYDSEALREKGVAIVQRLRDAVDLWKEETGYGFSLYSTPSENLCDRFCRLDTAE
FGVVEGVTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTP
IDECYECGFTGEFECTSKGFTCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG

Sequences:

>Translated_712_residues
MTPHVMKRDGCKVPFNSERIQEAILRAAKAAGVDDADYCATVAEVVSQQMQGRAQVDINEIQTAVENQLMSGPYKQLARA
YIEYRHDRDSQREKRGRLNQEIRGLVEQTNSALLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPHDVVMAHERGMIH
YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVSESF
KKHRKIAEEWQIPDAEGYARARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWESRLIQQSILRNRIAGLGK
NRKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQVH
DGRNNLGVISLNLPRIALEAKGDEAAFWALLDERLQLARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIF
KNGRASISLGYIGIHETINALYGNQHMYDSEALREKGVAIVQRLRDAVDLWKEETGYGFSLYSTPSENLCDRFCRLDTAE
FGVVEGVTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTP
IDECYECGFTGEFECTSKGFTCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
>Mature_711_residues
TPHVMKRDGCKVPFNSERIQEAILRAAKAAGVDDADYCATVAEVVSQQMQGRAQVDINEIQTAVENQLMSGPYKQLARAY
IEYRHDRDSQREKRGRLNQEIRGLVEQTNSALLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPHDVVMAHERGMIHY
HDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVSESFK
KHRKIAEEWQIPDAEGYARARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWESRLIQQSILRNRIAGLGKN
RKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQVHD
GRNNLGVISLNLPRIALEAKGDEAAFWALLDERLQLARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIFK
NGRASISLGYIGIHETINALYGNQHMYDSEALREKGVAIVQRLRDAVDLWKEETGYGFSLYSTPSENLCDRFCRLDTAEF
GVVEGVTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTPI
DECYECGFTGEFECTSKGFTCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=712, Percent_Identity=94.1011235955056, Blast_Score=1410, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 80046; Mature: 79914

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS51161 ATP_CONE ; PS00850 GLY_RADICAL_1 ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHVMKRDGCKVPFNSERIQEAILRAAKAAGVDDADYCATVAEVVSQQMQGRAQVDINE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
IQTAVENQLMSGPYKQLARAYIEYRHDRDSQREKRGRLNQEIRGLVEQTNSALLNENANK
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DSKVIPTQRDLLAGIVAKHYARQHLLPHDVVMAHERGMIHYHDLDYSPFFPMFNCMLIDL
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
KGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVSESF
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KKHRKIAEEWQIPDAEGYARARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHEEEECCCCCCEEEEECCCCCC
WESRLIQQSILRNRIAGLGKNRKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
MYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQVHDGRNNLGVISLNLPRIALEA
CCHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEC
KGDEAAFWALLDERLQLARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCEEEECCCCHHHHH
KNGRASISLGYIGIHETINALYGNQHMYDSEALREKGVAIVQRLRDAVDLWKEETGYGFS
HCCCCEEEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LYSTPSENLCDRFCRLDTAEFGVVEGVTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPL
EECCCCHHHHHHHHHCCCCHHCCEECCCCCCEEECEEEEEECCCCCCCCCCCCCCCCCCC
ANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGF
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCC
TCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPHVMKRDGCKVPFNSERIQEAILRAAKAAGVDDADYCATVAEVVSQQMQGRAQVDINE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
IQTAVENQLMSGPYKQLARAYIEYRHDRDSQREKRGRLNQEIRGLVEQTNSALLNENANK
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DSKVIPTQRDLLAGIVAKHYARQHLLPHDVVMAHERGMIHYHDLDYSPFFPMFNCMLIDL
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
KGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVSESF
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KKHRKIAEEWQIPDAEGYARARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHEEEECCCCCCEEEEECCCCCC
WESRLIQQSILRNRIAGLGKNRKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
MYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQVHDGRNNLGVISLNLPRIALEA
CCHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEC
KGDEAAFWALLDERLQLARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCEEEECCCCHHHHH
KNGRASISLGYIGIHETINALYGNQHMYDSEALREKGVAIVQRLRDAVDLWKEETGYGFS
HCCCCEEEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LYSTPSENLCDRFCRLDTAEFGVVEGVTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPL
EECCCCHHHHHHHHHCCCCHHCCEECCCCCCEEECEEEEEECCCCCCCCCCCCCCCCCCC
ANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGF
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCC
TCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]