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The map label for this gene is relE [H]

Identifier: 238892728

GI number: 238892728

Start: 512942

End: 513226

Strand: Direct

Name: relE [H]

Synonym: KP1_0521

Alternate gene names: 238892728

Gene position: 512942-513226 (Clockwise)

Preceding gene: 238892727

Following gene: 238892732

Centisome position: 9.77

GC content: 47.37

Gene sequence:

>285_bases
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Upstream 100 bases:

>100_bases
CCGGTGAAAAGTATGACCATCAGTGATGGCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCC
GGGGGTTAAGGTGAGTCTGG

Downstream 100 bases:

>100_bases
ACGCTATCGCAAATGATGTACGACCTGGTTGCTGCTGCCGCGCCAGATAAGCGCCGGATCTTTCAAATCCTGCACAAACT
TACCGTCAACCAGCACGTTA

Product: putative inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MTYELEFDPRAWREWQKPGETVKKQFKNKLQQIVQNPRIESTRLSDLPDCYKIKLKASGYRLVYQVRDSVVVVYVIAIGK
REKAAVYHQANKRL

Sequences:

>Translated_94_residues
MTYELEFDPRAWREWQKPGETVKKQFKNKLQQIVQNPRIESTRLSDLPDCYKIKLKASGYRLVYQVRDSVVVVYVIAIGK
REKAAVYHQANKRL
>Mature_93_residues
TYELEFDPRAWREWQKPGETVKKQFKNKLQQIVQNPRIESTRLSDLPDCYKIKLKASGYRLVYQVRDSVVVVYVIAIGKR
EKAAVYHQANKRL

Specific function: Inhibits translation during amino acid starvation. Acts by cleaving mRNA with high codon specificity in the ribosomal A site. UGA is cleaved with fast rate while UAA and UGA are cleaved with intermediate and slow rate, respectively. mRNA cleavage can also

COG id: COG2026

COG function: function code JD; Cytotoxic translational repressor of toxin-antitoxin stability system

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787846, Length=94, Percent_Identity=57.4468085106383, Blast_Score=120, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007712
- InterPro:   IPR012753 [H]

Pfam domain/function: PF05016 Plasmid_stabil [H]

EC number: NA

Molecular weight: Translated: 11156; Mature: 11025

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYELEFDPRAWREWQKPGETVKKQFKNKLQQIVQNPRIESTRLSDLPDCYKIKLKASGY
CCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCE
RLVYQVRDSVVVVYVIAIGKREKAAVYHQANKRL
EEEEEECCCEEEEEEEEECCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TYELEFDPRAWREWQKPGETVKKQFKNKLQQIVQNPRIESTRLSDLPDCYKIKLKASGY
CEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCE
RLVYQVRDSVVVVYVIAIGKREKAAVYHQANKRL
EEEEEECCCEEEEEEEEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2990907; 9097039; 9278503; 9767574; 12526800 [H]