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The map label for this gene is dipZ [H]

Identifier: 238892613

GI number: 238892613

Start: 400033

End: 401829

Strand: Reverse

Name: dipZ [H]

Synonym: KP1_0392

Alternate gene names: 238892613

Gene position: 401829-400033 (Counterclockwise)

Preceding gene: 238892614

Following gene: 238892612

Centisome position: 7.66

GC content: 62.83

Gene sequence:

>1797_bases
ATGGCTTACCGCATCATTACGCTGATCCTGCTGCTGTGCAGCACATCAGCCACCGCCGGGTTATTCGACGCGCCGGGGCG
CTCGAACTTCGTGCCTGCTGATCAAGCTTTCGCCTTTGACTTTCAGCAGCAACAGCATGACGTCAACCTGAGCTGGCAAA
TCAAGGATGGTTATTATCTTTATCGTCAACAGTTTACCTTCAGCGCCGCCGGGGCGACGATCGACGAACCGGCGCTGCCG
GCGGGAGAGTGGCATGAAGATGAGTTTTACGGCAAAAGCGAGATCTTTCGCCAACGCCTGACCGTGCCGGTGACGGTGAA
GGAGGCGGACAAAGAGGCTACTCTCACCGTCACCTGGCAGGGCTGCGCCGATGCCGGATTCTGTTATCCGCCGGAGACTA
AAGTGATCCCGCTGAGCGCCGTGCGGGCGGCCTCAAACGACGCTCAGCCAACCGCCGCCGCGCCCGTGTCGTCGCTGAAC
CATCGCCCGGCCTTCAATCCGCCGCTGCCGGTTGAACCGCGCCCGATGGAGGAGAACGCCGTGCTGCAGGCGCCTGCCAT
GGCGCCGCCAGCAGACGTCCCCGCTCGTCTGCCCTTCACCGCCCTGTGGGCGCTGCTGATTGGCATTGGTATCGCCTTCA
CCCCCTGCGTGCTGCCGATGTACCCGCTGATTTCGGGCATCGTGCTGGGCGGAAAACAGCGGCTTTCCACCGCGCGCGCC
CTGCTGCTGGCCTTTATTTACGTCCAGGGGATGGCCCTGACCTATACCGCGCTGGGGCTGGTGGTAGCCGCCGCCGGGCT
GCAGTTCCAGGCGGCCCTGCAGCACCCGTATGTCCTGGTCGGCCTGTCGGCGGTGTTTATACTGCTGGCGCTCTCCATGT
TCGGCCTGTTCACGCTGCAGCTGCCGTCGTCGCTGCAGACCCGGCTGACGCTGCTCAGCAATAAGCGCCAGGGCGGCTCG
CCCGGCGGGGTCTTTGCGATGGGCGCTATTGCCGGTCTGATCTGCTCTCCCTGCACCACCGCGCCGCTAAGCGCCATTCT
GTTGTATATCGCCCAGAGCGGTAATCTGTGGCTGGGCGGCGGCACGCTGTACCTTTACGCGCTGGGCATGGGTCTGCCGT
TGATCCTTGTGACCGTGTTTGGCAATCGCCTGCTGCCGAAAAGCGGCCCGTGGATGAGCCATGTGAAAACCGCCTTCGGG
TTTGTGATCCTTGCCCTGCCCGTCTTCCTGCTGGAACGCATATTCGGCGACCAGTGGGGGTTACGGCTGTGGTCAATGCT
CGGTGTCGCCTTCTTCAGCTGGGCGTTTATCACCTCGCTGGGCGCTACCCGGCCGTGGATGCGGCTGGTACAGATCATTC
TGCTTGCCGCCGCGCTGGTCAGCGCGCGGCCTCTGCAGGACTGGGCGTTTGGCGCCCCGGCGGTCGAGCAGCAGGCGCAC
CTGGCTTTCACCCGCGTCAGCTCGGTGGCCGAGCTTGACCAGGCGCTGGCGCAGGCGAAAGGTCAACCGGTGATGCTCGA
TCTTTACGCCGACTGGTGCGTGGCCTGCAAAGAGTTTGAAAAATACACCTTTAGTTCACCTGACGTGCAGCAGGCGCTGA
AAGGCACCGTGTTATTACAGGTCGATGTGACGAAGAACAACCCGCAAGACGTCGCGCTGCTGAGACACCTGCAGGTGCTG
GGTCTGCCGACGATCCTGTTCTTCAACGCTGAGGGTCAGGAACAGCCTGAGCGGCGAGTCACCGGCTTTATGGATGCCGC
GGCATTCAGCGCCCATTTGCGCGATTGGCAAGCGTGA

Upstream 100 bases:

>100_bases
ATCAGCAGGCGCTGCTGGACTGCCTGAAGTCACACCACCCGTATCAAACCCCAGAACTGCTGGTTCTACCCGTCACGCAT
GGAGACAACGATTACCTCTC

Downstream 100 bases:

>100_bases
GCGACACTTTAGGAGGAAAGATGGAGGAGAACACCGTGCTACGTGAAGACGTCCTGGCAGAAGCCATTAAGATTCTTGAA
ATTGAAGGTATCGCCAACAC

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MAYRIITLILLLCSTSATAGLFDAPGRSNFVPADQAFAFDFQQQQHDVNLSWQIKDGYYLYRQQFTFSAAGATIDEPALP
AGEWHEDEFYGKSEIFRQRLTVPVTVKEADKEATLTVTWQGCADAGFCYPPETKVIPLSAVRAASNDAQPTAAAPVSSLN
HRPAFNPPLPVEPRPMEENAVLQAPAMAPPADVPARLPFTALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARA
LLLAFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLVGLSAVFILLALSMFGLFTLQLPSSLQTRLTLLSNKRQGGS
PGGVFAMGAIAGLICSPCTTAPLSAILLYIAQSGNLWLGGGTLYLYALGMGLPLILVTVFGNRLLPKSGPWMSHVKTAFG
FVILALPVFLLERIFGDQWGLRLWSMLGVAFFSWAFITSLGATRPWMRLVQIILLAAALVSARPLQDWAFGAPAVEQQAH
LAFTRVSSVAELDQALAQAKGQPVMLDLYADWCVACKEFEKYTFSSPDVQQALKGTVLLQVDVTKNNPQDVALLRHLQVL
GLPTILFFNAEGQEQPERRVTGFMDAAAFSAHLRDWQA

Sequences:

>Translated_598_residues
MAYRIITLILLLCSTSATAGLFDAPGRSNFVPADQAFAFDFQQQQHDVNLSWQIKDGYYLYRQQFTFSAAGATIDEPALP
AGEWHEDEFYGKSEIFRQRLTVPVTVKEADKEATLTVTWQGCADAGFCYPPETKVIPLSAVRAASNDAQPTAAAPVSSLN
HRPAFNPPLPVEPRPMEENAVLQAPAMAPPADVPARLPFTALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARA
LLLAFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLVGLSAVFILLALSMFGLFTLQLPSSLQTRLTLLSNKRQGGS
PGGVFAMGAIAGLICSPCTTAPLSAILLYIAQSGNLWLGGGTLYLYALGMGLPLILVTVFGNRLLPKSGPWMSHVKTAFG
FVILALPVFLLERIFGDQWGLRLWSMLGVAFFSWAFITSLGATRPWMRLVQIILLAAALVSARPLQDWAFGAPAVEQQAH
LAFTRVSSVAELDQALAQAKGQPVMLDLYADWCVACKEFEKYTFSSPDVQQALKGTVLLQVDVTKNNPQDVALLRHLQVL
GLPTILFFNAEGQEQPERRVTGFMDAAAFSAHLRDWQA
>Mature_597_residues
AYRIITLILLLCSTSATAGLFDAPGRSNFVPADQAFAFDFQQQQHDVNLSWQIKDGYYLYRQQFTFSAAGATIDEPALPA
GEWHEDEFYGKSEIFRQRLTVPVTVKEADKEATLTVTWQGCADAGFCYPPETKVIPLSAVRAASNDAQPTAAAPVSSLNH
RPAFNPPLPVEPRPMEENAVLQAPAMAPPADVPARLPFTALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARAL
LLAFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLVGLSAVFILLALSMFGLFTLQLPSSLQTRLTLLSNKRQGGSP
GGVFAMGAIAGLICSPCTTAPLSAILLYIAQSGNLWLGGGTLYLYALGMGLPLILVTVFGNRLLPKSGPWMSHVKTAFGF
VILALPVFLLERIFGDQWGLRLWSMLGVAFFSWAFITSLGATRPWMRLVQIILLAAALVSARPLQDWAFGAPAVEQQAHL
AFTRVSSVAELDQALAQAKGQPVMLDLYADWCVACKEFEKYTFSSPDVQQALKGTVLLQVDVTKNNPQDVALLRHLQVLG
LPTILFFNAEGQEQPERRVTGFMDAAAFSAHLRDWQA

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=598, Percent_Identity=75.9197324414716, Blast_Score=899, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 64832; Mature: 64701

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYRIITLILLLCSTSATAGLFDAPGRSNFVPADQAFAFDFQQQQHDVNLSWQIKDGYYL
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHEECHHHHHCCCCEEEEECCCEEE
YRQQFTFSAAGATIDEPALPAGEWHEDEFYGKSEIFRQRLTVPVTVKEADKEATLTVTWQ
EEEEEEEEECCCCCCCCCCCCCCCCCHHHCCHHHHHHHHCCCEEEEECCCCCEEEEEEEC
GCADAGFCYPPETKVIPLSAVRAASNDAQPTAAAPVSSLNHRPAFNPPLPVEPRPMEENA
CCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
VLQAPAMAPPADVPARLPFTALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARA
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LLLAFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLVGLSAVFILLALSMFGLFTLQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
LPSSLQTRLTLLSNKRQGGSPGGVFAMGAIAGLICSPCTTAPLSAILLYIAQSGNLWLGG
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECC
GTLYLYALGMGLPLILVTVFGNRLLPKSGPWMSHVKTAFGFVILALPVFLLERIFGDQWG
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LRLWSMLGVAFFSWAFITSLGATRPWMRLVQIILLAAALVSARPLQDWAFGAPAVEQQAH
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHH
LAFTRVSSVAELDQALAQAKGQPVMLDLYADWCVACKEFEKYTFSSPDVQQALKGTVLLQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHCCEEEEE
VDVTKNNPQDVALLRHLQVLGLPTILFFNAEGQEQPERRVTGFMDAAAFSAHLRDWQA
EEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AYRIITLILLLCSTSATAGLFDAPGRSNFVPADQAFAFDFQQQQHDVNLSWQIKDGYYL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHEECHHHHHCCCCEEEEECCCEEE
YRQQFTFSAAGATIDEPALPAGEWHEDEFYGKSEIFRQRLTVPVTVKEADKEATLTVTWQ
EEEEEEEEECCCCCCCCCCCCCCCCCHHHCCHHHHHHHHCCCEEEEECCCCCEEEEEEEC
GCADAGFCYPPETKVIPLSAVRAASNDAQPTAAAPVSSLNHRPAFNPPLPVEPRPMEENA
CCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
VLQAPAMAPPADVPARLPFTALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARA
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LLLAFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLVGLSAVFILLALSMFGLFTLQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
LPSSLQTRLTLLSNKRQGGSPGGVFAMGAIAGLICSPCTTAPLSAILLYIAQSGNLWLGG
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECC
GTLYLYALGMGLPLILVTVFGNRLLPKSGPWMSHVKTAFGFVILALPVFLLERIFGDQWG
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LRLWSMLGVAFFSWAFITSLGATRPWMRLVQIILLAAALVSARPLQDWAFGAPAVEQQAH
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHH
LAFTRVSSVAELDQALAQAKGQPVMLDLYADWCVACKEFEKYTFSSPDVQQALKGTVLLQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHCCEEEEE
VDVTKNNPQDVALLRHLQVLGLPTILFFNAEGQEQPERRVTGFMDAAAFSAHLRDWQA
EEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA