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The map label for this gene is alr [H]

Identifier: 238892526

GI number: 238892526

Start: 308343

End: 309422

Strand: Direct

Name: alr [H]

Synonym: KP1_0295

Alternate gene names: 238892526

Gene position: 308343-309422 (Clockwise)

Preceding gene: 238892525

Following gene: 238892527

Centisome position: 5.87

GC content: 64.07

Gene sequence:

>1080_bases
ATGCAAGCGGCAACTGTAGTTATCAACCGCCGCGCTCTGCGACACAACCTGCAACGTCTGCGTGAACTGGCGCCCGCCAG
CAAACTGGTTGCGGTAGTGAAAGCGAACGCCTACGGACACGGTCTTCTCGAGACCGCGCGAACGCTGACCGACGCCGACG
CCTTTGGCGTCGCCCGCCTGGAAGAGGCGCTGCGCCTGCGAGCGGGGGGCATCGCCCAGCCGATCCTCCTGCTGGAAGGC
TTTTTTGCTGCGGAAGACCTGGCGGTGATCGCCGCCCAGCGCCTGCATACGGCGGTGCATAGCCCCGAACAGCTGGCGGC
GCTGGAGCAAGCCGATCTCCCCGAGCCGGTGACCGTGTGGATGAAGCTGGATACCGGCATGCATCGCTTAGGGGTGCGCC
CGGAGGAAGCCGAGGCGTTTTATCAGCGTCTGAGCCAGTGTAAAAACGTCCGCCAGCCGGTGAACGTGGTGAGCCACTTC
GCGCGCGCCGATGAGCCGACCTGCGGCGCCACCGAACGCCAGCTGGATATCTTCACCACCTTTACCGAAGGCAAACCGGG
GCTGCGCTCTATCGCCGCCTCGGGCGGCATTCTGCTGTGGCCGCAATCGCATTACGACTGGGTGCGCCCCGGAATTATCC
TGTATGGCGTGTCGCCGCTGGACGATCGCTCCACCGGCAGAGATTTCGGCTGCCAGCCGGTGATGACTCTAACGTCCAGC
CTGATTGCGGTGCGCGAGCATAAAGCAGGGGAGCCCGTCGGCTACGGCGGCACCTGGATCAGCGAACGCGATACCCGTCT
CGGCGTGGTGGCGATGGGCTATGGCGACGGTTATCCGCGCGCGGCACCGTCGGGCACGCCGGTGCTGGTCAATGGCCGGG
AAGTGCCGATTGTCGGCCGGGTGGCGATGGATATGATCTGCGTTGACCTCGGACCGCAGGCCCAGGATAAAGCCGGCGAC
GCGGTAGTGCTGTGGGGAGAGGGGCTCCCGGTAGAGCGCATCGCCGAGATAACGAAAGTAAGTGCTTACGAACTTATTAC
GCGACTGACCTCCCGCGTCGCCATGAAATACTTCGACTAA

Upstream 100 bases:

>100_bases
CGACTGACCTTTAACGGCCAGTGGTCGCGTTTCGATAATTATGCCGGTCCTCAGTATGATGATGAGTAATCCTTCCGCCT
TCTTTTATTAAGGAATTCAA

Downstream 100 bases:

>100_bases
GCCTCTGGCGTACCGGATAGCACAGAGGCTGATCCGGTACGCACCAGGCCTGCGGCGCTCAAAAAAGCGGTTTATACCGC
TGCGGGGTCACTTTCCCCTC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLTDADAFGVARLEEALRLRAGGIAQPILLLEG
FFAAEDLAVIAAQRLHTAVHSPEQLAALEQADLPEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLSQCKNVRQPVNVVSHF
ARADEPTCGATERQLDIFTTFTEGKPGLRSIAASGGILLWPQSHYDWVRPGIILYGVSPLDDRSTGRDFGCQPVMTLTSS
LIAVREHKAGEPVGYGGTWISERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGD
AVVLWGEGLPVERIAEITKVSAYELITRLTSRVAMKYFD

Sequences:

>Translated_359_residues
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLTDADAFGVARLEEALRLRAGGIAQPILLLEG
FFAAEDLAVIAAQRLHTAVHSPEQLAALEQADLPEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLSQCKNVRQPVNVVSHF
ARADEPTCGATERQLDIFTTFTEGKPGLRSIAASGGILLWPQSHYDWVRPGIILYGVSPLDDRSTGRDFGCQPVMTLTSS
LIAVREHKAGEPVGYGGTWISERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGD
AVVLWGEGLPVERIAEITKVSAYELITRLTSRVAMKYFD
>Mature_359_residues
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLTDADAFGVARLEEALRLRAGGIAQPILLLEG
FFAAEDLAVIAAQRLHTAVHSPEQLAALEQADLPEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLSQCKNVRQPVNVVSHF
ARADEPTCGATERQLDIFTTFTEGKPGLRSIAASGGILLWPQSHYDWVRPGIILYGVSPLDDRSTGRDFGCQPVMTLTSS
LIAVREHKAGEPVGYGGTWISERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGD
AVVLWGEGLPVERIAEITKVSAYELITRLTSRVAMKYFD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=359, Percent_Identity=89.9721448467967, Blast_Score=669, Evalue=0.0,
Organism=Escherichia coli, GI1787439, Length=348, Percent_Identity=43.3908045977011, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39027; Mature: 39027

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLTDADAFGVARL
CCCEEEEHHHHHHHHHHHHHHHHCCHHHEEHEEECCCCCCHHHHHHHHHHCCHHHHHHHH
EEALRLRAGGIAQPILLLEGFFAAEDLAVIAAQRLHTAVHSPEQLAALEQADLPEPVTVW
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEE
MKLDTGMHRLGVRPEEAEAFYQRLSQCKNVRQPVNVVSHFARADEPTCGATERQLDIFTT
EEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
FTEGKPGLRSIAASGGILLWPQSHYDWVRPGIILYGVSPLDDRSTGRDFGCQPVMTLTSS
ECCCCCCHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHH
LIAVREHKAGEPVGYGGTWISERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGR
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCCEEHH
VAMDMICVDLGPQAQDKAGDAVVLWGEGLPVERIAEITKVSAYELITRLTSRVAMKYFD
HHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLTDADAFGVARL
CCCEEEEHHHHHHHHHHHHHHHHCCHHHEEHEEECCCCCCHHHHHHHHHHCCHHHHHHHH
EEALRLRAGGIAQPILLLEGFFAAEDLAVIAAQRLHTAVHSPEQLAALEQADLPEPVTVW
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEE
MKLDTGMHRLGVRPEEAEAFYQRLSQCKNVRQPVNVVSHFARADEPTCGATERQLDIFTT
EEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
FTEGKPGLRSIAASGGILLWPQSHYDWVRPGIILYGVSPLDDRSTGRDFGCQPVMTLTSS
ECCCCCCHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHH
LIAVREHKAGEPVGYGGTWISERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGR
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCCEEHH
VAMDMICVDLGPQAQDKAGDAVVLWGEGLPVERIAEITKVSAYELITRLTSRVAMKYFD
HHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]