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The map label for this gene is yhcK [H]

Identifier: 238892462

GI number: 238892462

Start: 238159

End: 239691

Strand: Reverse

Name: yhcK [H]

Synonym: KP1_0227

Alternate gene names: 238892462

Gene position: 239691-238159 (Counterclockwise)

Preceding gene: 238892463

Following gene: 238892461

Centisome position: 4.57

GC content: 54.01

Gene sequence:

>1533_bases
ATGGCTCTACACAACAGAAAGCTCTCTTTTACGACGCCGATCGTCGTGGGGTTTGCCGGTATTTTGCTCAGTTTTATGCT
GATCGCTATTTTTGTGACTCTGGCGCAACAGAAAGATTTTCTCGAAGATTATCACGATATTAACCGCAATTTTACCCATA
ACCTGGCGATCAACTATACGGAAACCCTGCTGCGGGAAAATGATTTTATCCTCGGGCGCGCAGCCGCCTTCTTTGCCCGC
AATGACGAACTGAATCGCGCAGTCAATGTGGAGCCGGAGAAAGGGTTAACCACGCTGATGCAGTTACAGAACATGATGCC
AAGCGTCTCATCCATCTCGCTGGCGGATACCGAGGGCCACTATCTGCGCGCCCCGGAGGTGCTGGAAAACGAAGACAGTC
GGGCTTTCGATCCCAGAACGCGGCCCTGGTTTATCAAACAGGCGGAAGCCAGCACCTTCAGCCACTACACCAGTCCGTAT
ATGGATTATTTCACCCACCATCCGACGATTACCATTTTCAAACCCATCATTACCCCGGAAGGGAAACTCAAGGGCAGCCT
GGCCTTTCATCTCGATCTCACCTCCATGGGGTTCGCGCTGCGCCAGATGGTGGCGCCCGTACAGGGGGAATTTTTTGTGG
TGCAACGGGATGGCAAAGTGGTCCTGCACTCCGACCCGGGCGCGCTGTTTAAACCCTTCGTCAGGGACGAGCTGATGGAT
AAAATGACCAGCGGAGAGGGGCAGCTCTACGATCCCGGGAGCGACACCTGGTATTACTATTACTCCTTTACCAATCCCGA
CTGGTTTGTGATTTTCCGTGTCGATAACGCCACCCTGGTCAATCTGACACGTCATGAGACCAATTTAGTGATCGGCGGTT
TCACTCTCGCAGCGATCATTATTATCCTGTTCGGTCTTTATCTGCGTCATGCTTCCCGTTCCGTGCTGATGAATATCATC
AATGCGATTAAAACCGGTGACGTCAAACGCGCCCCGCGCCTTGAGGCGATGCTGAGTAAAGCGATTGAAACCAATAAACA
GCGCGAACTGTCCTACGTCCGCCAGGCGACCATCGACGCTCTCACCGGCTGCAAAAACCGCCGCGCCTTCGACAGCGATA
TTGCCGCCCTGATGAACGATCACCAGCCATTCGCCCTCGCGCTGGTCGATATCGATAACTTTAAATCGATCAACGACACC
TGGGGCCATCTCAATGGCGATATCGTCCTGCGTAACGTCGCTCGCGAAGGGCTACAGGTCCTCCAGCCGCTGGAGATATC
CCTCTATCGCTACGGCGGCGAAGAGTTCGCGGTGGTCTTTCCTGCCGAACATATCGATAACGCCCGCACGCTGCTGGAAA
CATGGCGGATAAACGTCGAACGACGCACCTGGCGCGAAGATGGCCTGACGGTCACCTTCAGCGCCGGACTTGGGGAATGG
AATATGGAGCCACTGGATAAGCTGGTGGTGAGCGTCGATGAAGCGCTGTACAAAGCCAAACAGCAGGGTAAAAACCGTAT
CCTGCGCGCGTAA

Upstream 100 bases:

>100_bases
GTTATAATTGAGCAATAGTGAACTGATTCGATCGGCAGGCGTCCCAGACGCAACCTGCGTTCGGACCCATGGTTTATACA
TCCGGGACGATTAACGATTC

Downstream 100 bases:

>100_bases
GACTTCAGCGCCGCCACCGCCCACTTCGGTGGGCTTTTTTATTTTTTCCGGAAAAAATGAAACCGGTTTCAATTATTGTG
TGATGCCTTACACACAATCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MALHNRKLSFTTPIVVGFAGILLSFMLIAIFVTLAQQKDFLEDYHDINRNFTHNLAINYTETLLRENDFILGRAAAFFAR
NDELNRAVNVEPEKGLTTLMQLQNMMPSVSSISLADTEGHYLRAPEVLENEDSRAFDPRTRPWFIKQAEASTFSHYTSPY
MDYFTHHPTITIFKPIITPEGKLKGSLAFHLDLTSMGFALRQMVAPVQGEFFVVQRDGKVVLHSDPGALFKPFVRDELMD
KMTSGEGQLYDPGSDTWYYYYSFTNPDWFVIFRVDNATLVNLTRHETNLVIGGFTLAAIIIILFGLYLRHASRSVLMNII
NAIKTGDVKRAPRLEAMLSKAIETNKQRELSYVRQATIDALTGCKNRRAFDSDIAALMNDHQPFALALVDIDNFKSINDT
WGHLNGDIVLRNVAREGLQVLQPLEISLYRYGGEEFAVVFPAEHIDNARTLLETWRINVERRTWREDGLTVTFSAGLGEW
NMEPLDKLVVSVDEALYKAKQQGKNRILRA

Sequences:

>Translated_510_residues
MALHNRKLSFTTPIVVGFAGILLSFMLIAIFVTLAQQKDFLEDYHDINRNFTHNLAINYTETLLRENDFILGRAAAFFAR
NDELNRAVNVEPEKGLTTLMQLQNMMPSVSSISLADTEGHYLRAPEVLENEDSRAFDPRTRPWFIKQAEASTFSHYTSPY
MDYFTHHPTITIFKPIITPEGKLKGSLAFHLDLTSMGFALRQMVAPVQGEFFVVQRDGKVVLHSDPGALFKPFVRDELMD
KMTSGEGQLYDPGSDTWYYYYSFTNPDWFVIFRVDNATLVNLTRHETNLVIGGFTLAAIIIILFGLYLRHASRSVLMNII
NAIKTGDVKRAPRLEAMLSKAIETNKQRELSYVRQATIDALTGCKNRRAFDSDIAALMNDHQPFALALVDIDNFKSINDT
WGHLNGDIVLRNVAREGLQVLQPLEISLYRYGGEEFAVVFPAEHIDNARTLLETWRINVERRTWREDGLTVTFSAGLGEW
NMEPLDKLVVSVDEALYKAKQQGKNRILRA
>Mature_509_residues
ALHNRKLSFTTPIVVGFAGILLSFMLIAIFVTLAQQKDFLEDYHDINRNFTHNLAINYTETLLRENDFILGRAAAFFARN
DELNRAVNVEPEKGLTTLMQLQNMMPSVSSISLADTEGHYLRAPEVLENEDSRAFDPRTRPWFIKQAEASTFSHYTSPYM
DYFTHHPTITIFKPIITPEGKLKGSLAFHLDLTSMGFALRQMVAPVQGEFFVVQRDGKVVLHSDPGALFKPFVRDELMDK
MTSGEGQLYDPGSDTWYYYYSFTNPDWFVIFRVDNATLVNLTRHETNLVIGGFTLAAIIIILFGLYLRHASRSVLMNIIN
AIKTGDVKRAPRLEAMLSKAIETNKQRELSYVRQATIDALTGCKNRRAFDSDIAALMNDHQPFALALVDIDNFKSINDTW
GHLNGDIVLRNVAREGLQVLQPLEISLYRYGGEEFAVVFPAEHIDNARTLLETWRINVERRTWREDGLTVTFSAGLGEWN
MEPLDKLVVSVDEALYKAKQQGKNRILRA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=37.5, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=35.2201257861635, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=32.2981366459627, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787056, Length=163, Percent_Identity=34.9693251533742, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787262, Length=158, Percent_Identity=32.9113924050633, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=137, Percent_Identity=37.2262773722628, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=34.1317365269461, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=35.3293413173653, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788381, Length=168, Percent_Identity=32.7380952380952, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786584, Length=160, Percent_Identity=33.75, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=31.2883435582822, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 58029; Mature: 57898

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHNRKLSFTTPIVVGFAGILLSFMLIAIFVTLAQQKDFLEDYHDINRNFTHNLAINYT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHH
ETLLRENDFILGRAAAFFARNDELNRAVNVEPEKGLTTLMQLQNMMPSVSSISLADTEGH
HHHHCCCCEEEEHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCC
YLRAPEVLENEDSRAFDPRTRPWFIKQAEASTFSHYTSPYMDYFTHHPTITIFKPIITPE
EEECCHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHCCHHHHHHHCCCEEEEEEEEECCC
GKLKGSLAFHLDLTSMGFALRQMVAPVQGEFFVVQRDGKVVLHSDPGALFKPFVRDELMD
CCCCCEEEEEEEHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHH
KMTSGEGQLYDPGSDTWYYYYSFTNPDWFVIFRVDNATLVNLTRHETNLVIGGFTLAAII
HHHCCCCEEECCCCCEEEEEEEECCCCEEEEEEECCEEEEEEEECCCCEEECHHHHHHHH
IILFGLYLRHASRSVLMNIINAIKTGDVKRAPRLEAMLSKAIETNKQRELSYVRQATIDA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LTGCKNRRAFDSDIAALMNDHQPFALALVDIDNFKSINDTWGHLNGDIVLRNVAREGLQV
HHCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHH
LQPLEISLYRYGGEEFAVVFPAEHIDNARTLLETWRINVERRTWREDGLTVTFSAGLGEW
HCCCEEEEEEECCCEEEEEECHHHCCHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCC
NMEPLDKLVVSVDEALYKAKQQGKNRILRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALHNRKLSFTTPIVVGFAGILLSFMLIAIFVTLAQQKDFLEDYHDINRNFTHNLAINYT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHH
ETLLRENDFILGRAAAFFARNDELNRAVNVEPEKGLTTLMQLQNMMPSVSSISLADTEGH
HHHHCCCCEEEEHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCC
YLRAPEVLENEDSRAFDPRTRPWFIKQAEASTFSHYTSPYMDYFTHHPTITIFKPIITPE
EEECCHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHCCHHHHHHHCCCEEEEEEEEECCC
GKLKGSLAFHLDLTSMGFALRQMVAPVQGEFFVVQRDGKVVLHSDPGALFKPFVRDELMD
CCCCCEEEEEEEHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHH
KMTSGEGQLYDPGSDTWYYYYSFTNPDWFVIFRVDNATLVNLTRHETNLVIGGFTLAAII
HHHCCCCEEECCCCCEEEEEEEECCCCEEEEEEECCEEEEEEEECCCCEEECHHHHHHHH
IILFGLYLRHASRSVLMNIINAIKTGDVKRAPRLEAMLSKAIETNKQRELSYVRQATIDA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LTGCKNRRAFDSDIAALMNDHQPFALALVDIDNFKSINDTWGHLNGDIVLRNVAREGLQV
HHCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHH
LQPLEISLYRYGGEEFAVVFPAEHIDNARTLLETWRINVERRTWREDGLTVTFSAGLGEW
HCCCEEEEEEECCCEEEEEECHHHCCHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCC
NMEPLDKLVVSVDEALYKAKQQGKNRILRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]