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The map label for this gene is adiA [H]

Identifier: 238028337

GI number: 238028337

Start: 3172512

End: 3174791

Strand: Reverse

Name: adiA [H]

Synonym: bglu_1g27980

Alternate gene names: 238028337

Gene position: 3174791-3172512 (Counterclockwise)

Preceding gene: 238028338

Following gene: 238028336

Centisome position: 81.27

GC content: 65.35

Gene sequence:

>2280_bases
ATGAAGTTTCGCTTTCCCGTCGTCATCATCGACGAAGATTTCCGTTCCGAGAACATCTCGGGCTCCGGCATCCGGGCGCT
TGCCGAAGCCATCGAGAAGGAGGGCGCGGAAGTGCTCGGCCTGACGAGCTACGGCGATCTGACCTCGTTCGCGCAGCAGT
CGAGCCGCGCGTCGTGCTTCATCCTGTCGATCGACGACGACGAACTGATGCTGGGCGAAACCGGTCCCGACGGCGAACTG
CCCGAGCTCGCCACGGCGATCCTCGAGCTGCGCGCGTTCGTGACCGAAGTGCGCCGCCGCAATGCCGACATCCCGATCTT
CCTGTACGGCGAGACGCGCACCTCGCGGCACATCCCGAACGACGTGCTGCGCGAGCTGCACGGCTTCATCCACATGTTCG
AGGACACGCCGGAGTTCGTCGCGCGCCACATCATCCGCGAAACCAAGGTCTACCTCGATTCGCTCGCGCCGCCGTTCTTC
AAGGAACTCGTCAAGTACGCCGACGAGGGGTCGTACTCGTGGCACTGCCCGGGACACTCGGGCGGCGTGGCGTTCCTGAA
GAATCCGCTCGGCCAGATGTTCCACCAGTTCTTCGGCGAGAACATGCTGCGCGCCGACGTCTGCAACGCCGTCGACGAAC
TCGGCCAGTTGCTCGACCACACCGGCCCGGTGGCGGCCTCGGAGCGCAATGCGGCGCGCATCTTCAGCGCCGACCACCTG
TTCTTCGTGACCAACGGCACCTCGACCTCGAACAAGATCGTCTGGCACGCCACCGTCGCGCCGGGCGACATCGTGCTGGT
GGACCGCAACTGCCACAAGTCGATCCTGCACGCGATCACGATGACGCATGCGATTCCGGTGTTCCTCACGCCGACGCGCA
ACCACTTCGGCATCATCGGCCCGATCCCGCGTGACGAGTTCAAGCCCGAGAACATCCGCAAGAAGATCGAGGCGAACCCG
TTCGCGCGCGAGGCGTTGAAGAAGAACCCGAACGCCAAGCCGCGGATCCTGACGATCACGCAGAGCACCTACGACGGCGT
GATCTACAACGTCGAGCAGATCAAGGATCTGCTCGGCGACCTGCTCGACACGCTGCACTTCGACGAGGCGTGGCTGCCGC
ACGCCGAATTCCACGAGTTCTACCAGGACATGCACGCGATCGGCGCGGGGCGGCCCCGCACCGGCGCGCTGGTGTTCGCG
ACGCACTCCACGCACAAGCTGCTGGCCGGCATCTCGCAGGCCTCGCAGATCGTGGTGCAGGATTCGGAGAACCGCACGTT
CGACAAGCACCGCTTCAACGAGGCCTACCTGATGCATACCTCGACGAGCCCGCAGTACGCGATCATCGCTTCGTGCGACG
TGGCCGCCGCGATGATGGAGCCGCCGGGCGGCACCGCGCTCGTCGAGGAGTCGATCGCCGAGGCGATCGAGTTCCGCCGC
GCGATGCGCAAGGTGGACGCCGAGTATGGCGACGACTGGTTCTTCTCGGTGTGGGGCCCGGACACGCTGCCCGACGAGGG
CATCGGCTCGCGCGAGGACTGGATGCTGCGCCCGAACGACCGCTGGCACGGCTTCGGCCCGCTCGCGGAAGGCTTCAACA
TGCTCGACCCGATCAAGGCCACGATCATCACGCCGGGCCTCGACGTGGACGGCGAGTTCGGCGAGACCGGGATTCCGGCC
GCGATCGTCACGAAGTATCTGGCCGAGCACGGCATCATCGTCGAGAAGACCGGGCTCTACTCGTTCTTCATCATGTTTAC
GATCGGCATCACCAAGGGCCGCTGGAACTCGATGGTCACCGAGCTGCAGCAGTTCAAGGACGACTACGACAACAACCAGC
CGCTCTGGCGCGTGCTGCCCGAGTTCGTCGCGCAGTATCCGATCTACGAGCGCGTCGGCCTGCGCGACCTCTGCACGCAG
ATCCACGACGTCTACCGCGCCAACGACATCGCGCGGCTGACCACCGAGATGTACCTGTCGGACATGGAGCCGGCGATGAA
GGCGTCCGACGCGTTCGCCAAGCTCGCGCACCGCGAGATCGACCGCGTGCCGCTCGACGAGCTCGAAGGCCGCGTGACCA
GCATCCTGCTCACGCCGTACCCGCCGGGCATCCCGCTGCTGATCCCGGGCGAGCGCTTCAATGCGACGATCGTCAGCTAC
CTGCGGTTCGCGCGCGACTTCAACGAGCGCTTCCCGGGCTTCCATACCGACGTCCACGGCCTCGTCGCCGAGGAACTGAA
CGGGCGCGTCGAGTACTACGTCGACTGCGTGCGCGACTGA

Upstream 100 bases:

>100_bases
CCGAAAACCTGATCTGGTTGTTTACGGTTGCATGCCAACCAGTGACCGGGTGACCGCCGCGCTTTGAGGCGCCGCGGTCG
TTCTTTTTGGAGATTCGCCC

Downstream 100 bases:

>100_bases
CGATGGCACGGTTCGGGACGATGCGCAGCGGCGGTGCGCTGGCCGCGGCGGTGCTGGCCCTGGCGGGCTTCGCCGGCGCG
GCCGCGCCGGCACGTGCGGA

Product: Orn/Lys/Arg decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 759; Mature: 759

Protein sequence:

>759_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELMLGETGPDGEL
PELATAILELRAFVTEVRRRNADIPIFLYGETRTSRHIPNDVLRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPPFF
KELVKYADEGSYSWHCPGHSGGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIGPIPRDEFKPENIRKKIEANP
FAREALKKNPNAKPRILTITQSTYDGVIYNVEQIKDLLGDLLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRTGALVFA
THSTHKLLAGISQASQIVVQDSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIEFRR
AMRKVDAEYGDDWFFSVWGPDTLPDEGIGSREDWMLRPNDRWHGFGPLAEGFNMLDPIKATIITPGLDVDGEFGETGIPA
AIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVAQYPIYERVGLRDLCTQ
IHDVYRANDIARLTTEMYLSDMEPAMKASDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNATIVSY
LRFARDFNERFPGFHTDVHGLVAEELNGRVEYYVDCVRD

Sequences:

>Translated_759_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELMLGETGPDGEL
PELATAILELRAFVTEVRRRNADIPIFLYGETRTSRHIPNDVLRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPPFF
KELVKYADEGSYSWHCPGHSGGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIGPIPRDEFKPENIRKKIEANP
FAREALKKNPNAKPRILTITQSTYDGVIYNVEQIKDLLGDLLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRTGALVFA
THSTHKLLAGISQASQIVVQDSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIEFRR
AMRKVDAEYGDDWFFSVWGPDTLPDEGIGSREDWMLRPNDRWHGFGPLAEGFNMLDPIKATIITPGLDVDGEFGETGIPA
AIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVAQYPIYERVGLRDLCTQ
IHDVYRANDIARLTTEMYLSDMEPAMKASDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNATIVSY
LRFARDFNERFPGFHTDVHGLVAEELNGRVEYYVDCVRD
>Mature_759_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELMLGETGPDGEL
PELATAILELRAFVTEVRRRNADIPIFLYGETRTSRHIPNDVLRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPPFF
KELVKYADEGSYSWHCPGHSGGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIGPIPRDEFKPENIRKKIEANP
FAREALKKNPNAKPRILTITQSTYDGVIYNVEQIKDLLGDLLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRTGALVFA
THSTHKLLAGISQASQIVVQDSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIEFRR
AMRKVDAEYGDDWFFSVWGPDTLPDEGIGSREDWMLRPNDRWHGFGPLAEGFNMLDPIKATIITPGLDVDGEFGETGIPA
AIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVAQYPIYERVGLRDLCTQ
IHDVYRANDIARLTTEMYLSDMEPAMKASDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNATIVSY
LRFARDFNERFPGFHTDVHGLVAEELNGRVEYYVDCVRD

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=777, Percent_Identity=37.0656370656371, Blast_Score=533, Evalue=1e-152,
Organism=Escherichia coli, GI1790573, Length=741, Percent_Identity=36.9770580296896, Blast_Score=493, Evalue=1e-140,
Organism=Escherichia coli, GI1786384, Length=726, Percent_Identity=36.9146005509642, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1786909, Length=672, Percent_Identity=32.7380952380952, Blast_Score=364, Evalue=1e-101,
Organism=Escherichia coli, GI87082193, Length=670, Percent_Identity=33.7313432835821, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85460; Mature: 85460

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCEEE
ILSIDDDELMLGETGPDGELPELATAILELRAFVTEVRRRNADIPIFLYGETRTSRHIPN
EEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
DVLRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPPFFKELVKYADEGSYSWHCPGHS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCC
GGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEE
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIG
EEEECCCCCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEC
PIPRDEFKPENIRKKIEANPFAREALKKNPNAKPRILTITQSTYDGVIYNVEQIKDLLGD
CCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHH
LLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRTGALVFATHSTHKLLAGISQASQIVVQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCEEEEE
DSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIEFRR
CCCCCCCHHHCCCCEEEEEECCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AMRKVDAEYGDDWFFSVWGPDTLPDEGIGSREDWMLRPNDRWHGFGPLAEGFNMLDPIKA
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCCCCCCCC
TIITPGLDVDGEFGETGIPAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVT
EEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHH
ELQQFKDDYDNNQPLWRVLPEFVAQYPIYERVGLRDLCTQIHDVYRANDIARLTTEMYLS
HHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMEPAMKASDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNATIVSY
HCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCEEECCCCCHHHHHHH
LRFARDFNERFPGFHTDVHGLVAEELNGRVEYYVDCVRD
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCC
>Mature Secondary Structure
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCEEE
ILSIDDDELMLGETGPDGELPELATAILELRAFVTEVRRRNADIPIFLYGETRTSRHIPN
EEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
DVLRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPPFFKELVKYADEGSYSWHCPGHS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCC
GGVAFLKNPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSADHL
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEE
FFVTNGTSTSNKIVWHATVAPGDIVLVDRNCHKSILHAITMTHAIPVFLTPTRNHFGIIG
EEEECCCCCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEC
PIPRDEFKPENIRKKIEANPFAREALKKNPNAKPRILTITQSTYDGVIYNVEQIKDLLGD
CCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHH
LLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRTGALVFATHSTHKLLAGISQASQIVVQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCEEEEE
DSENRTFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIAEAIEFRR
CCCCCCCHHHCCCCEEEEEECCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AMRKVDAEYGDDWFFSVWGPDTLPDEGIGSREDWMLRPNDRWHGFGPLAEGFNMLDPIKA
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCCCCCCCC
TIITPGLDVDGEFGETGIPAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVT
EEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHH
ELQQFKDDYDNNQPLWRVLPEFVAQYPIYERVGLRDLCTQIHDVYRANDIARLTTEMYLS
HHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMEPAMKASDAFAKLAHREIDRVPLDELEGRVTSILLTPYPPGIPLLIPGERFNATIVSY
HCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCEEECCCCCHHHHHHH
LRFARDFNERFPGFHTDVHGLVAEELNGRVEYYVDCVRD
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]