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The map label for this gene is otsA [H]

Identifier: 238028306

GI number: 238028306

Start: 3136062

End: 3137480

Strand: Reverse

Name: otsA [H]

Synonym: bglu_1g27670

Alternate gene names: 238028306

Gene position: 3137480-3136062 (Counterclockwise)

Preceding gene: 238028307

Following gene: 238028305

Centisome position: 80.31

GC content: 68.5

Gene sequence:

>1419_bases
ATGAGCAGATTGATCGTGGTTTCGAATCGTGTGGCAGCCGGGCAGGACACGCGTCCGTCGGCGGGCGGGCTCGCGGTGGG
CGTGCTCGATGCGCTGCAGCAGTCGGGCGGGATCTGGTTCGGGTGGAACGGCGAGATCGTCGGCGAGCCGGGCGAGCCGG
TGATCGAGCGCGAAGGCAACCTCACCTACGCGACGGTGGGGCTCACGCGGCGCGATTACGACCAGTATTACCGCGGCTTC
TCGAACGCCACGCTGTGGCCGGTATTCCACTACCGCATGGATCTCGCGCGCTTCGACCGGCAGGAGTACGAAGGCTATCA
GCGCGTGAACGCGACGCTCGCCGCGCAACTGCGTGCGCTGATCCGGCCCGACGACATCATCTGGGTTCACGATTACCACC
TGCTGCCGTTCGCGCACGCGCTGCGCGCGCTCGGCGTGCAGAACCCGATCGGCTTCTTCCTGCACATCCCGTTCCCCTCG
CCGGAGGTGCTGCGCACCGTGCCGCCGCACGAGGAGCTGGTCCGCTGCCTGTGCGCCTACGACGTGGTGGGTTTCCAGAC
CGAATCGGACCAGCAGGCGTTCGTCGACTACATCGAACGGCGCGGCATCGGCACCGCCAGCGAGGACGGCATGCTCCACG
TCCACGGCCGCGTCGTGAAGGTCGGCGCCTATCCGATCGGGGTCTATCCGGAGGCGATTGCGGAAGCCGCGCGCCAGCAT
GCGCAACGCAAGCCGGTGGCCGCGCTGCGCAACGCGGTCCGCGATCGCAAGCTGGTGATGAGCGTGGACCGGCTCGATTA
TTCGAAGGGGCTCGTCGAGCGCTTCCAGGCGTTCGAGCGGATGCTGGCCAGTGCGCCCGGCTGGCAGGGGCGCGTCTCGT
TCGTGCAGGTCGCGCCGCCGACGCGCTCCGACGTGCAGACCTACCAGCGGATTCGCCAGACGCTGGAGCAGGAGGCGGGC
CGTATCAACGGCCGCTTCGCGCAGCTCGACTGGACCCCGATCCAGTATCTGAACCGCAAGTACGAGCGCAACCTGCTGAT
GGCGCTGTTGCGGCATGCGCACGTCGGCTACGTGACGCCGCTGCGCGACGGCATGAATCTGGTTGCGAAGGAATACGTCG
CCTCGCAGAATCCCGAGGATCCCGGCGTGCTGGTGCTGTCCGAGTTCGCCGGTGCCGCGGCCGAGCTGCCGGGCGCGCTG
ATCGTCAATCCCGCCGACCTTTCGCAGATGGCCGAGGCGCTCGAGCGTGCGCTGTCGATGCCGCTCGGCGAGCGGCGCGA
GCGGCACGCCAGCAACTTCGCCGCGCTCAAGCGCAACGATCTCTCGGTGTGGCGCGATTCGTTCGTCTCGGACCTGCGCA
GCGTGGCCACGGCCGTGTCGGTCACGCAGCGCGCGGGACGGCGCACCGCGGATGCGTGA

Upstream 100 bases:

>100_bases
GCGTGACATCCGCGCCGTCGCGCCGGGCACCTCGCGTGCTTGCGACGGGGGACCGGGCGTGGTCACGCACCGTGGTATCC
AGCACAGGAGGTCAGGCCGT

Downstream 100 bases:

>100_bases
CGGCCAGCAGGCTGACTGGCCCGGCCAAGCCGGGCCAGTCAGAGCAACGCAGGCAAGGGGCGGCGCCGCGGCGCCGCCTT
TTTTCGTCGTCACAGGCGGG

Product: alpha,alpha-trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSRLIVVSNRVAAGQDTRPSAGGLAVGVLDALQQSGGIWFGWNGEIVGEPGEPVIEREGNLTYATVGLTRRDYDQYYRGF
SNATLWPVFHYRMDLARFDRQEYEGYQRVNATLAAQLRALIRPDDIIWVHDYHLLPFAHALRALGVQNPIGFFLHIPFPS
PEVLRTVPPHEELVRCLCAYDVVGFQTESDQQAFVDYIERRGIGTASEDGMLHVHGRVVKVGAYPIGVYPEAIAEAARQH
AQRKPVAALRNAVRDRKLVMSVDRLDYSKGLVERFQAFERMLASAPGWQGRVSFVQVAPPTRSDVQTYQRIRQTLEQEAG
RINGRFAQLDWTPIQYLNRKYERNLLMALLRHAHVGYVTPLRDGMNLVAKEYVASQNPEDPGVLVLSEFAGAAAELPGAL
IVNPADLSQMAEALERALSMPLGERRERHASNFAALKRNDLSVWRDSFVSDLRSVATAVSVTQRAGRRTADA

Sequences:

>Translated_472_residues
MSRLIVVSNRVAAGQDTRPSAGGLAVGVLDALQQSGGIWFGWNGEIVGEPGEPVIEREGNLTYATVGLTRRDYDQYYRGF
SNATLWPVFHYRMDLARFDRQEYEGYQRVNATLAAQLRALIRPDDIIWVHDYHLLPFAHALRALGVQNPIGFFLHIPFPS
PEVLRTVPPHEELVRCLCAYDVVGFQTESDQQAFVDYIERRGIGTASEDGMLHVHGRVVKVGAYPIGVYPEAIAEAARQH
AQRKPVAALRNAVRDRKLVMSVDRLDYSKGLVERFQAFERMLASAPGWQGRVSFVQVAPPTRSDVQTYQRIRQTLEQEAG
RINGRFAQLDWTPIQYLNRKYERNLLMALLRHAHVGYVTPLRDGMNLVAKEYVASQNPEDPGVLVLSEFAGAAAELPGAL
IVNPADLSQMAEALERALSMPLGERRERHASNFAALKRNDLSVWRDSFVSDLRSVATAVSVTQRAGRRTADA
>Mature_471_residues
SRLIVVSNRVAAGQDTRPSAGGLAVGVLDALQQSGGIWFGWNGEIVGEPGEPVIEREGNLTYATVGLTRRDYDQYYRGFS
NATLWPVFHYRMDLARFDRQEYEGYQRVNATLAAQLRALIRPDDIIWVHDYHLLPFAHALRALGVQNPIGFFLHIPFPSP
EVLRTVPPHEELVRCLCAYDVVGFQTESDQQAFVDYIERRGIGTASEDGMLHVHGRVVKVGAYPIGVYPEAIAEAARQHA
QRKPVAALRNAVRDRKLVMSVDRLDYSKGLVERFQAFERMLASAPGWQGRVSFVQVAPPTRSDVQTYQRIRQTLEQEAGR
INGRFAQLDWTPIQYLNRKYERNLLMALLRHAHVGYVTPLRDGMNLVAKEYVASQNPEDPGVLVLSEFAGAAAELPGALI
VNPADLSQMAEALERALSMPLGERRERHASNFAALKRNDLSVWRDSFVSDLRSVATAVSVTQRAGRRTADA

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=465, Percent_Identity=51.3978494623656, Blast_Score=486, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI115533558, Length=357, Percent_Identity=31.0924369747899, Blast_Score=158, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI115533560, Length=357, Percent_Identity=31.0924369747899, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI71987012, Length=426, Percent_Identity=28.4037558685446, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319602, Length=466, Percent_Identity=33.2618025751073, Blast_Score=284, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6320279, Length=424, Percent_Identity=29.7169811320755, Blast_Score=190, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6323917, Length=373, Percent_Identity=28.1501340482574, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323537, Length=431, Percent_Identity=28.0742459396752, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19920676, Length=484, Percent_Identity=35.3305785123967, Blast_Score=282, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 52802; Mature: 52670

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIVVSNRVAAGQDTRPSAGGLAVGVLDALQQSGGIWFGWNGEIVGEPGEPVIEREGN
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCEECCCCCCCCEECCCC
LTYATVGLTRRDYDQYYRGFSNATLWPVFHYRMDLARFDRQEYEGYQRVNATLAAQLRAL
EEEEEECCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRPDDIIWVHDYHLLPFAHALRALGVQNPIGFFLHIPFPSPEVLRTVPPHEELVRCLCAY
CCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHH
DVVGFQTESDQQAFVDYIERRGIGTASEDGMLHVHGRVVKVGAYPIGVYPEAIAEAARQH
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECEECCCCHHHHHHHHHHH
AQRKPVAALRNAVRDRKLVMSVDRLDYSKGLVERFQAFERMLASAPGWQGRVSFVQVAPP
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
TRSDVQTYQRIRQTLEQEAGRINGRFAQLDWTPIQYLNRKYERNLLMALLRHAHVGYVTP
CHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEECC
LRDGMNLVAKEYVASQNPEDPGVLVLSEFAGAAAELPGALIVNPADLSQMAEALERALSM
HHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCHHHHCCCEEEECHHHHHHHHHHHHHHHCC
PLGERRERHASNFAALKRNDLSVWRDSFVSDLRSVATAVSVTQRAGRRTADA
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRLIVVSNRVAAGQDTRPSAGGLAVGVLDALQQSGGIWFGWNGEIVGEPGEPVIEREGN
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCEECCCCCCCCEECCCC
LTYATVGLTRRDYDQYYRGFSNATLWPVFHYRMDLARFDRQEYEGYQRVNATLAAQLRAL
EEEEEECCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRPDDIIWVHDYHLLPFAHALRALGVQNPIGFFLHIPFPSPEVLRTVPPHEELVRCLCAY
CCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHH
DVVGFQTESDQQAFVDYIERRGIGTASEDGMLHVHGRVVKVGAYPIGVYPEAIAEAARQH
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECEECCCCHHHHHHHHHHH
AQRKPVAALRNAVRDRKLVMSVDRLDYSKGLVERFQAFERMLASAPGWQGRVSFVQVAPP
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
TRSDVQTYQRIRQTLEQEAGRINGRFAQLDWTPIQYLNRKYERNLLMALLRHAHVGYVTP
CHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEECC
LRDGMNLVAKEYVASQNPEDPGVLVLSEFAGAAAELPGALIVNPADLSQMAEALERALSM
HHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCHHHHCCCEEEECHHHHHHHHHHHHHHHCC
PLGERRERHASNFAALKRNDLSVWRDSFVSDLRSVATAVSVTQRAGRRTADA
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA