Click here to switch to the map view.

The map label for this gene is eco [C]

Identifier: 238028297

GI number: 238028297

Start: 3129517

End: 3130056

Strand: Reverse

Name: eco [C]

Synonym: bglu_1g27570

Alternate gene names: 238028297

Gene position: 3130056-3129517 (Counterclockwise)

Preceding gene: 238028299

Following gene: 238028289

Centisome position: 80.12

GC content: 69.44

Gene sequence:

>540_bases
ATGCGTCGTTCGTTCCGGCTGTCCCTCGTATTTACCGCGGCCGTGGTGTCGCTCGGCGGCGCGCATCTGGCGTCCGCGCA
GTCCGTTGCTTCGGGCGCCGCCGCGTCGGCACCGGCTGCGGCGGCGGCCGCCGCCGATCTGAAAATGTTCCCGGCTCCGC
AGCCCGGCATGCAGCGCGCGGTGATCTCGCTGCCGCCGGCCGAACTCGAGGACGACCTGCGCGTGCAGGTGATCGTCGGC
AAGACGATGCCGACCGATTGCAACGTCCATTTCTTTCCGGCGCGCTTGCAGCACGACACCTTGCCGGGCTCGGGCTATCC
GTACTACCGCGTGACCGACATCGGCCCGGTGGCCGCCACCAAAATGGCCTGCGCGCCGTCGGCCACGCCGCAGTCGGCGT
TCGTGATCGGCCGCGGCGACGGTTTTTTGCTGCGTTACAACAGCCGCCTGCCGGTGGTCGTCTACGTGCCCGACGGCTAT
GAGGTGCGCTACCGGCTCTGGCAGGGGTCCAACGAGGTCGGGCGCGCGGTGGTGCGTTGA

Upstream 100 bases:

>100_bases
CCGCGGCGCGCGCCGGCGCAGGTTCCCGGGCGGCTCGCCCGTTTCAACCGGTTTCAACCGATTCGATCCACTTGCCCGAT
TCGTCAAACAGGAGATCCGT

Downstream 100 bases:

>100_bases
GCGCGCCGCCGCCGATGAAGCCACGGCAGGCGCGGTGCTAGCGTAGCGAGCAGGCCAGCCAGTTGCGGATGCGGATCGCG
TCGGCGACATGGTCGCGCGG

Product: Ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MRRSFRLSLVFTAAVVSLGGAHLASAQSVASGAAASAPAAAAAAADLKMFPAPQPGMQRAVISLPPAELEDDLRVQVIVG
KTMPTDCNVHFFPARLQHDTLPGSGYPYYRVTDIGPVAATKMACAPSATPQSAFVIGRGDGFLLRYNSRLPVVVYVPDGY
EVRYRLWQGSNEVGRAVVR

Sequences:

>Translated_179_residues
MRRSFRLSLVFTAAVVSLGGAHLASAQSVASGAAASAPAAAAAAADLKMFPAPQPGMQRAVISLPPAELEDDLRVQVIVG
KTMPTDCNVHFFPARLQHDTLPGSGYPYYRVTDIGPVAATKMACAPSATPQSAFVIGRGDGFLLRYNSRLPVVVYVPDGY
EVRYRLWQGSNEVGRAVVR
>Mature_179_residues
MRRSFRLSLVFTAAVVSLGGAHLASAQSVASGAAASAPAAAAAAADLKMFPAPQPGMQRAVISLPPAELEDDLRVQVIVG
KTMPTDCNVHFFPARLQHDTLPGSGYPYYRVTDIGPVAATKMACAPSATPQSAFVIGRGDGFLLRYNSRLPVVVYVPDGY
EVRYRLWQGSNEVGRAVVR

Specific function: General Inhibitor Of Pancreatic Serine Proteases: Inhibits Chymotrypsin, Trypsin, Elastases, Factor X, Kallikrein As Well As A Variety Of Other Proteases. The Strength Of Inhibition Does Not Appear To Be Correlated With A Particular Protease Specificity.

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=153, Percent_Identity=41.8300653594771, Blast_Score=126, Evalue=9e-31,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 19003; Mature: 19003

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSFRLSLVFTAAVVSLGGAHLASAQSVASGAAASAPAAAAAAADLKMFPAPQPGMQRA
CCCEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHCCEEECCCCCCCCCEE
VISLPPAELEDDLRVQVIVGKTMPTDCNVHFFPARLQHDTLPGSGYPYYRVTDIGPVAAT
EEECCCCCCCCCCEEEEEECCCCCCCCCEEEEECEEECCCCCCCCCCEEEEECCCCCHHH
KMACAPSATPQSAFVIGRGDGFLLRYNSRLPVVVYVPDGYEVRYRLWQGSNEVGRAVVR
HEECCCCCCCCCEEEEECCCEEEEEECCCCCEEEECCCCCEEEEEEECCCCHHHHHHCC
>Mature Secondary Structure
MRRSFRLSLVFTAAVVSLGGAHLASAQSVASGAAASAPAAAAAAADLKMFPAPQPGMQRA
CCCEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHCCEEECCCCCCCCCEE
VISLPPAELEDDLRVQVIVGKTMPTDCNVHFFPARLQHDTLPGSGYPYYRVTDIGPVAAT
EEECCCCCCCCCCEEEEEECCCCCCCCCEEEEECEEECCCCCCCCCCEEEEECCCCCHHH
KMACAPSATPQSAFVIGRGDGFLLRYNSRLPVVVYVPDGYEVRYRLWQGSNEVGRAVVR
HEECCCCCCCCCEEEEECCCEEEEEECCCCCEEEECCCCCEEEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA