Click here to switch to the map view.

The map label for this gene is rlmH [H]

Identifier: 238028188

GI number: 238028188

Start: 3004908

End: 3005378

Strand: Direct

Name: rlmH [H]

Synonym: bglu_1g26400

Alternate gene names: 238028188

Gene position: 3004908-3005378 (Clockwise)

Preceding gene: 238028187

Following gene: 238028189

Centisome position: 76.92

GC content: 70.06

Gene sequence:

>471_bases
ATGAAGCTGCAAATCGTCGCGGTCGGCCACAAGATGCCCGGCTGGGTGTCCACCGGTTTCGACGAATACGCGAAGCGGAT
GCCGCCCGAGCTGCGGCTCGAGCTGCGCGAGATCAAGCCCGAGCTGCGCTCGGGCGGCCGCAGCGCCGAGAGCGTGATGG
CGGCCGAGAAGACGCGGATCGAGGCCGCGCTGCCGAAGCACGCGCGTGTCGTCGCGCTCGACGAGCGCGGCCGCGACTGG
ACCTCGATGCAGCTCGCGCAGGCGCTGCCCGGCTGGCAGCAGGACGGCCACGACGTGGCATTCGTGATCGGCGGCGCCGA
CGGGCTCGACCCGGAGCTGAAGGCGCGCGCCGATCTGCTGCTGCGGATCTCCAGCCTCACGCTGCCGCACGGCATGGTGC
GCGTGCTGCTGGCCGAGCAGCTTTACCGCGCGTGGAGCATCACGCAGAATCATCCCTACCACCGAGCATGA

Upstream 100 bases:

>100_bases
GCGACGAGGACAACGCCCCGCTCGCCCGCAAGACGCCCGCGCGGCGCCGTTGAGCACGGCCGCGCCGCTACCCGCCGCTG
TCACGCGCTGACGTCACGCC

Downstream 100 bases:

>100_bases
CGCGCCGCGTTCGCGACTCGTCATGCGGCCACCGAGAACCATGACGATGTCCGACCGCCTCCTGCCCGACTCGACCTATC
CGTTCGTCTATCTCGCCTCG

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKLQIVAVGHKMPGWVSTGFDEYAKRMPPELRLELREIKPELRSGGRSAESVMAAEKTRIEAALPKHARVVALDERGRDW
TSMQLAQALPGWQQDGHDVAFVIGGADGLDPELKARADLLLRISSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA

Sequences:

>Translated_156_residues
MKLQIVAVGHKMPGWVSTGFDEYAKRMPPELRLELREIKPELRSGGRSAESVMAAEKTRIEAALPKHARVVALDERGRDW
TSMQLAQALPGWQQDGHDVAFVIGGADGLDPELKARADLLLRISSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
>Mature_156_residues
MKLQIVAVGHKMPGWVSTGFDEYAKRMPPELRLELREIKPELRSGGRSAESVMAAEKTRIEAALPKHARVVALDERGRDW
TSMQLAQALPGWQQDGHDVAFVIGGADGLDPELKARADLLLRISSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA [H]

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family [H]

Homologues:

Organism=Escherichia coli, GI1786855, Length=155, Percent_Identity=50.9677419354839, Blast_Score=150, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016051
- InterPro:   IPR003742 [H]

Pfam domain/function: PF02590 SPOUT_MTase [H]

EC number: NA

Molecular weight: Translated: 17453; Mature: 17453

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQIVAVGHKMPGWVSTGFDEYAKRMPPELRLELREIKPELRSGGRSAESVMAAEKTRI
CEEEEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHH
EAALPKHARVVALDERGRDWTSMQLAQALPGWQQDGHDVAFVIGGADGLDPELKARADLL
HHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
LRISSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKLQIVAVGHKMPGWVSTGFDEYAKRMPPELRLELREIKPELRSGGRSAESVMAAEKTRI
CEEEEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHH
EAALPKHARVVALDERGRDWTSMQLAQALPGWQQDGHDVAFVIGGADGLDPELKARADLL
HHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
LRISSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA