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The map label for this gene is nuoF2 [H]

Identifier: 238028138

GI number: 238028138

Start: 2952636

End: 2953952

Strand: Reverse

Name: nuoF2 [H]

Synonym: bglu_1g25890

Alternate gene names: 238028138

Gene position: 2953952-2952636 (Counterclockwise)

Preceding gene: 238028139

Following gene: 238028137

Centisome position: 75.62

GC content: 65.07

Gene sequence:

>1317_bases
ATGACGTCCCTGCACGATCGTCACATCAAACCGCTGATTCTCGCGAACCTGAACGGTGAGAACTGGCGCCTCGAAGACTA
CGTCGCGCGCGGCGGCTACCAGCAGCTGCGCCGCATCATCGAGGAAAAGATTCCGCCTGAGCAGGTGATCGCCGACGTCA
AGGCGTCGGGCCTGCGCGGCCGCGGCGGCGCGGGCTTTCCGACCGGCCTCAAGTGGAGCTTCATGCCGCGCCAGTTCCCG
GGCCAGAAGTATCTGGTCTGCAACTCGGACGAAGGCGAGCCTGGCACCTTCAAGGACCGCGACATCCTGCGCTGGAACCC
GCATGCCGTGATCGAGGGCATGGCGATCGGCGCCTACGCGATGGGCATCACGGCCGGCTACAACTACATCCACGGCGAGA
TCTTCGAAGTGTATCGACGCTTCGAGGCGGCGCTCGAGGAAGCACGCGCGGCAGGCTATCTCGGCGCGAACATCCTCGGT
TCGGAGTTTTCGTTCCAGCTCCATGCGCACCATGGTTACGGTGCGTACGTCTGCGGCGAGGAAACGGCGCTGCTCGAATC
GCTCGAAGGCAAGAAGGGCCAGCCGCGCTTCAAGCCGCCGTTCCCGGCGAGCTTCGGTGTGTACGGCAAGCCGACCACCA
TCAACAACACCGAAACCTTCGCAGCCGTGCCGTTCCTGCTGGCGGTCGGTCCGCAGCATTACCTCGAGCTCGGCAAGCCG
AACAACGGCGGCACGAAGATCTTCTCGGTGTCGGGCGACGTCGAGCGCCCCGGCAACTACGAAGTGCCACTCGGCACGCC
GTTCTCGGCGCTGCTCGAACTGGCGGGCGGCATGCGCGGCGGCCGCAAGCTGAAGGCCGTGATTCCTGGCGGATCGTCGG
CGCCGGTGATTCCGGGCGACACGATGATGCAGATCGACATGGACTACGACTCGATCGCGAAGGCGGGCTCGATGCTCGGC
TCGGGCGCGGTGATCGTGATGGACGAGACGCGCTGCATGGTGCGCTCGCTGCTGCGCCTGTCCTACTTTTACTACGAGGA
ATCGTGCGGCCAGTGCACGCCGTGCCGTGAAGGCACCGGCTGGCTGTATCGCGTGGTGAAGCGCATCGAGGACGGGCAAG
GCCGCAAGGAAGACCTGGACCTGCTGAACTCGGTGGCCGAGAACATCATGGGACGCACGATCTGCGCGCTCGGCGATGCG
GCCGCGATGCCGGTGCGCGGCATGCTCAAGCACTACTGGGATGAATTCGCCTACCACGTCGAGCACAAGCACTGCATGGT
CGGAACTCATTCGCACGCGCCGGCCGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCGCCTGCGGCGACGCGCCGGTATTGCTGCTCAACAATCACAAGATGTGCAGTTTCATGAGCCGCGAGAAGATCGACCAG
CTGCTTGAGGAGCTCTCGAA

Downstream 100 bases:

>100_bases
CGTGAAAGCCGGCCCAGTCCGGCCAACCCGATAGCGGAACATCAGCGCCCGGCGGGCGAGAGCGCGAGCGAGCGTAAAAG
GTTAAGGACCATACATCATC

Product: NADH dehydrogenase subunit F

Products: NA

Alternate protein names: NADH dehydrogenase I subunit F 2; NDH-1 subunit F 2 [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MTSLHDRHIKPLILANLNGENWRLEDYVARGGYQQLRRIIEEKIPPEQVIADVKASGLRGRGGAGFPTGLKWSFMPRQFP
GQKYLVCNSDEGEPGTFKDRDILRWNPHAVIEGMAIGAYAMGITAGYNYIHGEIFEVYRRFEAALEEARAAGYLGANILG
SEFSFQLHAHHGYGAYVCGEETALLESLEGKKGQPRFKPPFPASFGVYGKPTTINNTETFAAVPFLLAVGPQHYLELGKP
NNGGTKIFSVSGDVERPGNYEVPLGTPFSALLELAGGMRGGRKLKAVIPGGSSAPVIPGDTMMQIDMDYDSIAKAGSMLG
SGAVIVMDETRCMVRSLLRLSYFYYEESCGQCTPCREGTGWLYRVVKRIEDGQGRKEDLDLLNSVAENIMGRTICALGDA
AAMPVRGMLKHYWDEFAYHVEHKHCMVGTHSHAPAVAA

Sequences:

>Translated_438_residues
MTSLHDRHIKPLILANLNGENWRLEDYVARGGYQQLRRIIEEKIPPEQVIADVKASGLRGRGGAGFPTGLKWSFMPRQFP
GQKYLVCNSDEGEPGTFKDRDILRWNPHAVIEGMAIGAYAMGITAGYNYIHGEIFEVYRRFEAALEEARAAGYLGANILG
SEFSFQLHAHHGYGAYVCGEETALLESLEGKKGQPRFKPPFPASFGVYGKPTTINNTETFAAVPFLLAVGPQHYLELGKP
NNGGTKIFSVSGDVERPGNYEVPLGTPFSALLELAGGMRGGRKLKAVIPGGSSAPVIPGDTMMQIDMDYDSIAKAGSMLG
SGAVIVMDETRCMVRSLLRLSYFYYEESCGQCTPCREGTGWLYRVVKRIEDGQGRKEDLDLLNSVAENIMGRTICALGDA
AAMPVRGMLKHYWDEFAYHVEHKHCMVGTHSHAPAVAA
>Mature_437_residues
TSLHDRHIKPLILANLNGENWRLEDYVARGGYQQLRRIIEEKIPPEQVIADVKASGLRGRGGAGFPTGLKWSFMPRQFPG
QKYLVCNSDEGEPGTFKDRDILRWNPHAVIEGMAIGAYAMGITAGYNYIHGEIFEVYRRFEAALEEARAAGYLGANILGS
EFSFQLHAHHGYGAYVCGEETALLESLEGKKGQPRFKPPFPASFGVYGKPTTINNTETFAAVPFLLAVGPQHYLELGKPN
NGGTKIFSVSGDVERPGNYEVPLGTPFSALLELAGGMRGGRKLKAVIPGGSSAPVIPGDTMMQIDMDYDSIAKAGSMLGS
GAVIVMDETRCMVRSLLRLSYFYYEESCGQCTPCREGTGWLYRVVKRIEDGQGRKEDLDLLNSVAENIMGRTICALGDAA
AMPVRGMLKHYWDEFAYHVEHKHCMVGTHSHAPAVAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI20149568, Length=414, Percent_Identity=47.1014492753623, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI260656005, Length=414, Percent_Identity=47.1014492753623, Blast_Score=383, Evalue=1e-106,
Organism=Escherichia coli, GI1788620, Length=402, Percent_Identity=41.7910447761194, Blast_Score=332, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17531727, Length=440, Percent_Identity=45.2272727272727, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI19920794, Length=413, Percent_Identity=45.5205811138014, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI45550452, Length=404, Percent_Identity=45.7920792079208, Blast_Score=358, Evalue=5e-99,
Organism=Drosophila melanogaster, GI24653819, Length=407, Percent_Identity=37.5921375921376, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24653817, Length=407, Percent_Identity=33.9066339066339, Blast_Score=223, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR011537
- InterPro:   IPR011538
- InterPro:   IPR019554 [H]

Pfam domain/function: PF01512 Complex1_51K; PF10589 NADH_4Fe-4S; PF10531 SLBB [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 48016; Mature: 47885

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLHDRHIKPLILANLNGENWRLEDYVARGGYQQLRRIIEEKIPPEQVIADVKASGLRG
CCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCC
RGGAGFPTGLKWSFMPRQFPGQKYLVCNSDEGEPGTFKDRDILRWNPHAVIEGMAIGAYA
CCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHH
MGITAGYNYIHGEIFEVYRRFEAALEEARAAGYLGANILGSEFSFQLHAHHGYGAYVCGE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEEEEECCCEEEEECC
ETALLESLEGKKGQPRFKPPFPASFGVYGKPTTINNTETFAAVPFLLAVGPQHYLELGKP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCC
NNGGTKIFSVSGDVERPGNYEVPLGTPFSALLELAGGMRGGRKLKAVIPGGSSAPVIPGD
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
TMMQIDMDYDSIAKAGSMLGSGAVIVMDETRCMVRSLLRLSYFYYEESCGQCTPCREGTG
CEEEEECCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
WLYRVVKRIEDGQGRKEDLDLLNSVAENIMGRTICALGDAAAMPVRGMLKHYWDEFAYHV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHH
EHKHCMVGTHSHAPAVAA
CCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TSLHDRHIKPLILANLNGENWRLEDYVARGGYQQLRRIIEEKIPPEQVIADVKASGLRG
CCCCCCCCCEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCC
RGGAGFPTGLKWSFMPRQFPGQKYLVCNSDEGEPGTFKDRDILRWNPHAVIEGMAIGAYA
CCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHH
MGITAGYNYIHGEIFEVYRRFEAALEEARAAGYLGANILGSEFSFQLHAHHGYGAYVCGE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEEEEECCCEEEEECC
ETALLESLEGKKGQPRFKPPFPASFGVYGKPTTINNTETFAAVPFLLAVGPQHYLELGKP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCC
NNGGTKIFSVSGDVERPGNYEVPLGTPFSALLELAGGMRGGRKLKAVIPGGSSAPVIPGD
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
TMMQIDMDYDSIAKAGSMLGSGAVIVMDETRCMVRSLLRLSYFYYEESCGQCTPCREGTG
CEEEEECCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
WLYRVVKRIEDGQGRKEDLDLLNSVAENIMGRTICALGDAAAMPVRGMLKHYWDEFAYHV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHH
EHKHCMVGTHSHAPAVAA
CCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]