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The map label for this gene is nuoL [H]

Identifier: 238028132

GI number: 238028132

Start: 2945466

End: 2947511

Strand: Reverse

Name: nuoL [H]

Synonym: bglu_1g25830

Alternate gene names: 238028132

Gene position: 2947511-2945466 (Counterclockwise)

Preceding gene: 238028133

Following gene: 238028131

Centisome position: 75.45

GC content: 62.37

Gene sequence:

>2046_bases
ATGTCGACCACACTCAATGAAAATCTGCTGCTCGCGATCGCGCTCGCGCCGCTTGCCGGCTCGATCATCGCCGGCCTGTT
CGGCAACACGGTCGGGCGCAAGGGCGCGCACCGCGTGACGATCCTCGGCGTGACGATCTCGTTCGTCCTGTCGATGGTGG
TGTTCCTGCAGGTGCTGGACGGCGCGAGCTTCAACGCGACCGTCTACGAATGGATGCACGTCGGGCCGCTCAAGCTCGAA
GTCGGCTTTCTCGTCGATTCGCTGACGGCGATGATGATGGTCGTCGTGACCTTCGTCTCGCTGATGGTGCATGTCTACAC
GATCGGCTACATGCAGGACGAGGACGGCTACCAGCGCTTCTTCTCCTACATCTCGCTGTTCACGTTCTCGATGCTGATGC
TCGTGATGAGCAACAACTTCCTGCAGCTGTTCTTCGGCTGGGAAGCGGTCGGCCTCGTGTCCTACCTGCTGATCGGCTTC
TACTTCACGCGGGAAAGCGCGATCTACGCGAACATGAAGGCGTTCATCGTCAACCGCGTCGGCGATTTCGGCTTCCTGCT
CGGCATCGGCCTGCTGCTCGCCTATGCCGGCTCGATGAACTACGGCGAGGTGTTCGCCAAGAGCACCGCGCTGGCCGCGA
TGCATTTCCCGGGCACCAACTGGGGCCTGCTGACGGTGGCCTGCATCTGCCTGTTCATCGGCGCGATGGGCAAGTCGGCG
CAGTTCCCGCTGCACGTCTGGCTGCCCGACTCGATGGAAGGCCCCACGCCGATCTCGGCGCTGATCCACGCGGCCACCAT
GGTGACGGCCGGCGTGTTCATGGTCACGCGCATGTCGCCGCTGTTCGAACTGTCCGACACCGCGCTGTCGTTCATCACCG
TGATCGGCGCGATCACGGCGCTGTTCATGGGCTTCCTCGGGGTGATCCAGAACGACATCAAGCGCGTGGTCGCGTACTCG
ACGCTCTCGCAGCTCGGCTACATGACGGTCGCGCTCGGCGTGTCGGCCTACCCGGTCGCCGTGTTCCACCTGATGACGCA
CGCGTTCTTCAAGGCGCTGCTGTTCCTCGCGGCCGGCTCGGTGATCATCGGCATGCACCACGACCAGGACATCCGCAACA
TGGGCGGCCTGCGCAAGTACATGCCGATCACCTGGATCACCTCGCTGGTCGGTTCGCTCGCCCTGATCGGTACGCCGTTC
TTCTCGGGTTTCTACTCGAAGGACTCGATCATCGACGCGGTGAAACTGTCGCACCTGCCGGGCTCTGGTTTCGCGTATTT
TGCAGTGGTCGCCAGTGTCTTCGTGACCGCCCTCTATTCGTTCCGCATGTATTTCCTGGTGTTCCACGGTGAAGAGCGCT
TCCGCAAGCCGAAGCATCCCGATTCGCCGATGGGCAAGGCCGCCGCGCAGGGTCATGACGCGCACGGCCACCACGATGAT
CATGTCCACGAACCGCACGAAACGTCGTGGGTCGTCTGGTTGCCGCTCGTGTTGCTCGCGATTCCGTCGGTGGTGATCGG
CGCGATCGCGATCGGCCCGATGCTGTTCGGCGATTTCTTCCAGCACGGCGTCGCGTTCGACAAGGTGATCTTCATCGGCC
AGAATCACCCGGCAGTCGCCGAGATGGCCGATGAATTCCACGGCTGGGCCGCGATGGGCCTGCACTCGGTGACGGGCCTG
CCGGTCTGGCTCGCACTGGCTGGCGTCGTCGTCGCCTGGTTCCTGTATCTGAAGCGCCCGGATCTGTCGGCGGCGATTCG
CCGTGCGGCCGGCCCGATCTATACGCTGCTCGATAACAAATACTACATGGACAAGATCAACGAGGTCGTATTCGCCAGGG
GTTCGGTTGCAGTCGGCCGTGGCCTCTGGAAAGAGGGCGACGTCGTCGTGATCGATGGGCTCGTCAACGGCAGTGCGCGG
TTCGTCAGCTGGTTCGCCGGCGTGATCCGCTTCCTGCAGTCCGGCTACATTTATCACTACGCGTTCGCGATGATCATTGG
CATGTTGGGTCTCCTCACCCTGTTTGTTACGCTCGGCGGCAAATAA

Upstream 100 bases:

>100_bases
CGATCGGCCTGGCAATCCTGGTCACGCTGTTCCGCAAACTCGACACCATCAACGTCGAGGATCTCGACCAGCTCAAGGGC
TAATCTCAGGCGAGTCTGCT

Downstream 100 bases:

>100_bases
GAAAGGAGAGGAACCCACTCATGCCCGCATTTCCGATTCTCAGTACCGCCATCTGGCTTCCGATCGTGTTCGGCCTCGTG
ATTCTGGCCATCGGCACGGA

Product: NADH:ubiquinone oxidoreductase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 681; Mature: 680

Protein sequence:

>681_residues
MSTTLNENLLLAIALAPLAGSIIAGLFGNTVGRKGAHRVTILGVTISFVLSMVVFLQVLDGASFNATVYEWMHVGPLKLE
VGFLVDSLTAMMMVVVTFVSLMVHVYTIGYMQDEDGYQRFFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGF
YFTRESAIYANMKAFIVNRVGDFGFLLGIGLLLAYAGSMNYGEVFAKSTALAAMHFPGTNWGLLTVACICLFIGAMGKSA
QFPLHVWLPDSMEGPTPISALIHAATMVTAGVFMVTRMSPLFELSDTALSFITVIGAITALFMGFLGVIQNDIKRVVAYS
TLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLAAGSVIIGMHHDQDIRNMGGLRKYMPITWITSLVGSLALIGTPF
FSGFYSKDSIIDAVKLSHLPGSGFAYFAVVASVFVTALYSFRMYFLVFHGEERFRKPKHPDSPMGKAAAQGHDAHGHHDD
HVHEPHETSWVVWLPLVLLAIPSVVIGAIAIGPMLFGDFFQHGVAFDKVIFIGQNHPAVAEMADEFHGWAAMGLHSVTGL
PVWLALAGVVVAWFLYLKRPDLSAAIRRAAGPIYTLLDNKYYMDKINEVVFARGSVAVGRGLWKEGDVVVIDGLVNGSAR
FVSWFAGVIRFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK

Sequences:

>Translated_681_residues
MSTTLNENLLLAIALAPLAGSIIAGLFGNTVGRKGAHRVTILGVTISFVLSMVVFLQVLDGASFNATVYEWMHVGPLKLE
VGFLVDSLTAMMMVVVTFVSLMVHVYTIGYMQDEDGYQRFFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGF
YFTRESAIYANMKAFIVNRVGDFGFLLGIGLLLAYAGSMNYGEVFAKSTALAAMHFPGTNWGLLTVACICLFIGAMGKSA
QFPLHVWLPDSMEGPTPISALIHAATMVTAGVFMVTRMSPLFELSDTALSFITVIGAITALFMGFLGVIQNDIKRVVAYS
TLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLAAGSVIIGMHHDQDIRNMGGLRKYMPITWITSLVGSLALIGTPF
FSGFYSKDSIIDAVKLSHLPGSGFAYFAVVASVFVTALYSFRMYFLVFHGEERFRKPKHPDSPMGKAAAQGHDAHGHHDD
HVHEPHETSWVVWLPLVLLAIPSVVIGAIAIGPMLFGDFFQHGVAFDKVIFIGQNHPAVAEMADEFHGWAAMGLHSVTGL
PVWLALAGVVVAWFLYLKRPDLSAAIRRAAGPIYTLLDNKYYMDKINEVVFARGSVAVGRGLWKEGDVVVIDGLVNGSAR
FVSWFAGVIRFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK
>Mature_680_residues
STTLNENLLLAIALAPLAGSIIAGLFGNTVGRKGAHRVTILGVTISFVLSMVVFLQVLDGASFNATVYEWMHVGPLKLEV
GFLVDSLTAMMMVVVTFVSLMVHVYTIGYMQDEDGYQRFFSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFY
FTRESAIYANMKAFIVNRVGDFGFLLGIGLLLAYAGSMNYGEVFAKSTALAAMHFPGTNWGLLTVACICLFIGAMGKSAQ
FPLHVWLPDSMEGPTPISALIHAATMVTAGVFMVTRMSPLFELSDTALSFITVIGAITALFMGFLGVIQNDIKRVVAYST
LSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLAAGSVIIGMHHDQDIRNMGGLRKYMPITWITSLVGSLALIGTPFF
SGFYSKDSIIDAVKLSHLPGSGFAYFAVVASVFVTALYSFRMYFLVFHGEERFRKPKHPDSPMGKAAAQGHDAHGHHDDH
VHEPHETSWVVWLPLVLLAIPSVVIGAIAIGPMLFGDFFQHGVAFDKVIFIGQNHPAVAEMADEFHGWAAMGLHSVTGLP
VWLALAGVVVAWFLYLKRPDLSAAIRRAAGPIYTLLDNKYYMDKINEVVFARGSVAVGRGLWKEGDVVVIDGLVNGSARF
VSWFAGVIRFLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=386, Percent_Identity=40.1554404145078, Blast_Score=289, Evalue=7e-78,
Organism=Escherichia coli, GI1788614, Length=610, Percent_Identity=38.8524590163934, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1788829, Length=417, Percent_Identity=29.7362110311751, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1788831, Length=396, Percent_Identity=29.2929292929293, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788827, Length=402, Percent_Identity=28.6069651741293, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI2367154, Length=128, Percent_Identity=34.375, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693160, Length=227, Percent_Identity=25.9911894273128, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788613, Length=398, Percent_Identity=23.3668341708543, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR002128
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01010 Oxidored_q1_C; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 74372; Mature: 74240

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTLNENLLLAIALAPLAGSIIAGLFGNTVGRKGAHRVTILGVTISFVLSMVVFLQVLD
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHC
GASFNATVYEWMHVGPLKLEVGFLVDSLTAMMMVVVTFVSLMVHVYTIGYMQDEDGYQRF
CCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHH
FSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFYFTRESAIYANMKAFIVNRV
HHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
GDFGFLLGIGLLLAYAGSMNYGEVFAKSTALAAMHFPGTNWGLLTVACICLFIGAMGKSA
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCC
QFPLHVWLPDSMEGPTPISALIHAATMVTAGVFMVTRMSPLFELSDTALSFITVIGAITA
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LFMGFLGVIQNDIKRVVAYSTLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLAAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VIIGMHHDQDIRNMGGLRKYMPITWITSLVGSLALIGTPFFSGFYSKDSIIDAVKLSHLP
EEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHCCCC
GSGFAYFAVVASVFVTALYSFRMYFLVFHGEERFRKPKHPDSPMGKAAAQGHDAHGHHDD
CCCHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCCCCCCCCCHHHHCCCCCCCCCCC
HVHEPHETSWVVWLPLVLLAIPSVVIGAIAIGPMLFGDFFQHGVAFDKVIFIGQNHPAVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHH
EMADEFHGWAAMGLHSVTGLPVWLALAGVVVAWFLYLKRPDLSAAIRRAAGPIYTLLDNK
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEHHCCC
YYMDKINEVVFARGSVAVGRGLWKEGDVVVIDGLVNGSARFVSWFAGVIRFLQSGYIYHY
HHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHH
AFAMIIGMLGLLTLFVTLGGK
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STTLNENLLLAIALAPLAGSIIAGLFGNTVGRKGAHRVTILGVTISFVLSMVVFLQVLD
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHC
GASFNATVYEWMHVGPLKLEVGFLVDSLTAMMMVVVTFVSLMVHVYTIGYMQDEDGYQRF
CCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHH
FSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFYFTRESAIYANMKAFIVNRV
HHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
GDFGFLLGIGLLLAYAGSMNYGEVFAKSTALAAMHFPGTNWGLLTVACICLFIGAMGKSA
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCC
QFPLHVWLPDSMEGPTPISALIHAATMVTAGVFMVTRMSPLFELSDTALSFITVIGAITA
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LFMGFLGVIQNDIKRVVAYSTLSQLGYMTVALGVSAYPVAVFHLMTHAFFKALLFLAAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VIIGMHHDQDIRNMGGLRKYMPITWITSLVGSLALIGTPFFSGFYSKDSIIDAVKLSHLP
EEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHCCCC
GSGFAYFAVVASVFVTALYSFRMYFLVFHGEERFRKPKHPDSPMGKAAAQGHDAHGHHDD
CCCHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCCCCCCCCCHHHHCCCCCCCCCCC
HVHEPHETSWVVWLPLVLLAIPSVVIGAIAIGPMLFGDFFQHGVAFDKVIFIGQNHPAVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHH
EMADEFHGWAAMGLHSVTGLPVWLALAGVVVAWFLYLKRPDLSAAIRRAAGPIYTLLDNK
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEHHCCC
YYMDKINEVVFARGSVAVGRGLWKEGDVVVIDGLVNGSARFVSWFAGVIRFLQSGYIYHY
HHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHH
AFAMIIGMLGLLTLFVTLGGK
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]