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The map label for this gene is nuoN [H]

Identifier: 238028130

GI number: 238028130

Start: 2942455

End: 2943912

Strand: Reverse

Name: nuoN [H]

Synonym: bglu_1g25810

Alternate gene names: 238028130

Gene position: 2943912-2942455 (Counterclockwise)

Preceding gene: 238028131

Following gene: 238028129

Centisome position: 75.36

GC content: 63.99

Gene sequence:

>1458_bases
ATGAATGCCTTGTTGCCCGACGCGCTCGTGATGTTCGCCATCATCGTGGCGTGGCTGAACGACACCCTGGCCGGCGAATC
CGGCCGTCGTTTCACGTTCCTGATCGCGGTCGTCTCCTCGATTGCCGCCGGTGTGTGGTTTGCGGTCCAGGCCTTCGATC
CGCACCAGTACTACTTCTTCTCGCGCATGATCGTGGTCGATTCGTTCGCGAGCGTGATGAAGTCGGTGGTCTCGTTCGGC
TACGGCGTGTCGCTGATCTACTCGCGACGCTATCTGGCCGATCGCGGTCTGTTCCGCGGCGACGTGTTCCTGCTCGGGAT
GTTCTCGCTGCTCGGCCAGCTCGTGATGATCTCGGGCAACAACTTCCTGACGCTGTATCTCGGCCTGGAACTGATGTCGC
TGTCGCTGTACGCCCTGATCGCGCTGCGCCGCGACGGCGCGCAGTCGAGCGAAGCGGCGATGAAGTACTACGTGCTCGGC
GCGCTGGCTTCCGGCTTCGTGCTCTACGGCATCTCGATGCTGTACGGCGCGTCCGGTTCGCTCGAACTGCACGACGTGCT
GAACGCGATCGCCTCGGGCCGCATCAACGACGCGGTGCTGCTGTTCGGCGTGATCTTCGTGGTGGCGGGCGTGGCCTTCA
AGCTCGGCGCGGTGCCGTTCCACATGTGGGTGCCCGACGTCTATCAGGGCGCCCCCACGGCGATGTCGCTGTTCACGGGC
GGCGGCCCCAAGGTGGCCGCGTTCGCCTGGGGCCTGCGCTTCCTCGTGATGGGCCTGCTGCCGCTCGCGGCCGACTGGCA
GCAGATGCTGGTGATCCTCGCGGCGCTGTCGCTGATCGTCGGCAACATCACCGGCATCGTCCAGCGCAACGTCAAGCGGA
TGCTCGCGTATTCGGCGATCTCGAACATGGGCTTCGTGCTGCTCGGCTTGCTGTCGGGCGTCGTGAAGGGTGCGCCGACG
TTCGCGGCCACTGCCTATAGCTCGGCGATGTTCTACTCGATCGTCTATCTGATCACCACGCTCGGCGCGTTCGGCATCGT
GATGCTGCTGGCCCGCCGTGACTTCGAGGCGGAGACGCTCGATGATTTCAAGGGCCTGAACAAGCGCAGCCCGGTGTTCG
CGTTCGTGATGATGGTGATGATGTTCTCGCTGGCCGGCATTCCGCCGACGGTCGGCTTCTACGCCAAGCTCGCGGTGCTC
GAGGCGACCATCAACGCCGGCCTGACCTGGCTTGCGATCCTTGGTGTCATCTCCTCGTTGTTCGGCGCGTTCTACTATTT
GCGTATCGTGAAGCTGATGTACTTCGACGCGCCGCAGGACAGCAATCCGATCATGAGCGACTCGCTGAACCGCGGCGTGC
TGCTGCTCAACGGCGCTGCCGTGGTGGTGCTCGGTGTCGCGCCCAGCAGGCTGATCGAAATCTGCCTGCAGGCGATCACC
CACACGCTGCCGCTCTGA

Upstream 100 bases:

>100_bases
TTCCGTAGAAAACCTCCTCTCTCACGTCGCGCAATCCAAGCTGCCGCTGTCCCCGCAGTAAGGGTGGGCGGAGGAAACCA
AGACCATGCAAAACGCACCT

Downstream 100 bases:

>100_bases
TGTCCGCGGCCGGCTGGTTCATCGTGCTGCTGGCGCTTGCCGGCGCCAACCTGCCGTTCTTGAATCAACGCCTGTTCGCC
GTCGTGCCGGTTGGTGCCGG

Product: NADH:ubiquinone oxidoreductase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNALLPDALVMFAIIVAWLNDTLAGESGRRFTFLIAVVSSIAAGVWFAVQAFDPHQYYFFSRMIVVDSFASVMKSVVSFG
YGVSLIYSRRYLADRGLFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYALIALRRDGAQSSEAAMKYYVLG
ALASGFVLYGISMLYGASGSLELHDVLNAIASGRINDAVLLFGVIFVVAGVAFKLGAVPFHMWVPDVYQGAPTAMSLFTG
GGPKVAAFAWGLRFLVMGLLPLAADWQQMLVILAALSLIVGNITGIVQRNVKRMLAYSAISNMGFVLLGLLSGVVKGAPT
FAATAYSSAMFYSIVYLITTLGAFGIVMLLARRDFEAETLDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVL
EATINAGLTWLAILGVISSLFGAFYYLRIVKLMYFDAPQDSNPIMSDSLNRGVLLLNGAAVVVLGVAPSRLIEICLQAIT
HTLPL

Sequences:

>Translated_485_residues
MNALLPDALVMFAIIVAWLNDTLAGESGRRFTFLIAVVSSIAAGVWFAVQAFDPHQYYFFSRMIVVDSFASVMKSVVSFG
YGVSLIYSRRYLADRGLFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYALIALRRDGAQSSEAAMKYYVLG
ALASGFVLYGISMLYGASGSLELHDVLNAIASGRINDAVLLFGVIFVVAGVAFKLGAVPFHMWVPDVYQGAPTAMSLFTG
GGPKVAAFAWGLRFLVMGLLPLAADWQQMLVILAALSLIVGNITGIVQRNVKRMLAYSAISNMGFVLLGLLSGVVKGAPT
FAATAYSSAMFYSIVYLITTLGAFGIVMLLARRDFEAETLDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVL
EATINAGLTWLAILGVISSLFGAFYYLRIVKLMYFDAPQDSNPIMSDSLNRGVLLLNGAAVVVLGVAPSRLIEICLQAIT
HTLPL
>Mature_485_residues
MNALLPDALVMFAIIVAWLNDTLAGESGRRFTFLIAVVSSIAAGVWFAVQAFDPHQYYFFSRMIVVDSFASVMKSVVSFG
YGVSLIYSRRYLADRGLFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYALIALRRDGAQSSEAAMKYYVLG
ALASGFVLYGISMLYGASGSLELHDVLNAIASGRINDAVLLFGVIFVVAGVAFKLGAVPFHMWVPDVYQGAPTAMSLFTG
GGPKVAAFAWGLRFLVMGLLPLAADWQQMLVILAALSLIVGNITGIVQRNVKRMLAYSAISNMGFVLLGLLSGVVKGAPT
FAATAYSSAMFYSIVYLITTLGAFGIVMLLARRDFEAETLDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVL
EATINAGLTWLAILGVISSLFGAFYYLRIVKLMYFDAPQDSNPIMSDSLNRGVLLLNGAAVVVLGVAPSRLIEICLQAIT
HTLPL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=320, Percent_Identity=25.625, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI145693160, Length=486, Percent_Identity=33.9506172839506, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1788614, Length=387, Percent_Identity=23.7726098191214, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788831, Length=309, Percent_Identity=27.1844660194175, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788827, Length=328, Percent_Identity=27.4390243902439, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788613, Length=329, Percent_Identity=26.7477203647416, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI2367154, Length=263, Percent_Identity=24.7148288973384, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52307; Mature: 52307

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALLPDALVMFAIIVAWLNDTLAGESGRRFTFLIAVVSSIAAGVWFAVQAFDPHQYYFF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHH
SRMIVVDSFASVMKSVVSFGYGVSLIYSRRYLADRGLFRGDVFLLGMFSLLGQLVMISGN
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCC
NFLTLYLGLELMSLSLYALIALRRDGAQSSEAAMKYYVLGALASGFVLYGISMLYGASGS
CEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LELHDVLNAIASGRINDAVLLFGVIFVVAGVAFKLGAVPFHMWVPDVYQGAPTAMSLFTG
EEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCHHHHCCC
GGPKVAAFAWGLRFLVMGLLPLAADWQQMLVILAALSLIVGNITGIVQRNVKRMLAYSAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNMGFVLLGLLSGVVKGAPTFAATAYSSAMFYSIVYLITTLGAFGIVMLLARRDFEAETL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVLEATINAGLTWLAILGVISSL
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FGAFYYLRIVKLMYFDAPQDSNPIMSDSLNRGVLLLNGAAVVVLGVAPSRLIEICLQAIT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHH
HTLPL
HHCCC
>Mature Secondary Structure
MNALLPDALVMFAIIVAWLNDTLAGESGRRFTFLIAVVSSIAAGVWFAVQAFDPHQYYFF
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHH
SRMIVVDSFASVMKSVVSFGYGVSLIYSRRYLADRGLFRGDVFLLGMFSLLGQLVMISGN
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCC
NFLTLYLGLELMSLSLYALIALRRDGAQSSEAAMKYYVLGALASGFVLYGISMLYGASGS
CEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LELHDVLNAIASGRINDAVLLFGVIFVVAGVAFKLGAVPFHMWVPDVYQGAPTAMSLFTG
EEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCHHHHCCC
GGPKVAAFAWGLRFLVMGLLPLAADWQQMLVILAALSLIVGNITGIVQRNVKRMLAYSAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNMGFVLLGLLSGVVKGAPTFAATAYSSAMFYSIVYLITTLGAFGIVMLLARRDFEAETL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYAKLAVLEATINAGLTWLAILGVISSL
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FGAFYYLRIVKLMYFDAPQDSNPIMSDSLNRGVLLLNGAAVVVLGVAPSRLIEICLQAIT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHH
HTLPL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA