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The map label for this gene is paaF [H]

Identifier: 238028119

GI number: 238028119

Start: 2933448

End: 2934239

Strand: Direct

Name: paaF [H]

Synonym: bglu_1g25700

Alternate gene names: 238028119

Gene position: 2933448-2934239 (Clockwise)

Preceding gene: 238028117

Following gene: 238028120

Centisome position: 75.09

GC content: 70.58

Gene sequence:

>792_bases
ATGAGCGCCGAACTGCTCGCGTCCCGCCCCGTCGACAGCGCGTCGACTCTCGTCCTGACGCTGTCCAACCCCGGCGCGCG
CAACGCGCTGCATCCCGACATCTACGCGGCCGGCATCGAGGCGATGAACGCCGCCGAGCGCGACGCCTCGATCGGCGCGG
TAGTGCTGACCGGTGCCGATCGCTTCTTCTGCGCGGGCGGCAACCTCAACCGCCTGCTCGAAAATCGCGCCAAGGCCCCG
GCGGTGCAGGCCGCGAGCATCGACCTGCTCGGCGAATGGATCACCGCGATCCGCGCCATGTCCAAGCCGGTGATCGCGGC
GGTAGAGGGCGCGGCGGCCGGTGCCGGCTTCTCGCTCGCGCTCGCCTGCGATCTGATCGTCGCCGCCGACGACGCCAAGT
TCGTGATGTCCTACGCGCGGGTCGGGCTGACGCCGGACGGCGGCGGCTCGTGGTTTCTCGCGCGGGCGCTGCCACGGGCA
CTCGCGACCGAACTCTTGATCGAGGGCAAGCAGACCAGCGCGAAGCGCCTGCACGATCTCGGCGTCGTCAACCGCCTCGC
GCGCCCCGGCAGCGCACTCGGTGACGCGCTGGCCTGGGCTGACGAACTCGGCGGCGTCTCGCCGAATGCCATCGCGCGCG
TGAAGGCGCTGCTCGCGCAAGCCCCCGACCATTCGTTGGCCACCCATTTGGCCGCCGAACGCGACCACTTCGTGGCCTCG
CTGCACCATCCGGACGGACTCGAAGGCATCACCGCGTTTCTCGAGAAGCGCCCGCCCTCCTACACCCGCTGA

Upstream 100 bases:

>100_bases
AACCGGACGCGCACCCAGAAATGTATCGCGCGCGCCGGTATCGCGGCAGCACGCCCCTTCTGCCGCCAACCACGAGACGG
CCTATCAGGAGACACATCGC

Downstream 100 bases:

>100_bases
TTACGCGCCCCCGCCCATGCCCGCCGACTCAGACATGACCGCCTACGCCCTGCCCAAGCGCCGCCGCATCTACCTGATGC
GCCACGGCGACGTGACCTAT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSAELLASRPVDSASTLVLTLSNPGARNALHPDIYAAGIEAMNAAERDASIGAVVLTGADRFFCAGGNLNRLLENRAKAP
AVQAASIDLLGEWITAIRAMSKPVIAAVEGAAAGAGFSLALACDLIVAADDAKFVMSYARVGLTPDGGGSWFLARALPRA
LATELLIEGKQTSAKRLHDLGVVNRLARPGSALGDALAWADELGGVSPNAIARVKALLAQAPDHSLATHLAAERDHFVAS
LHHPDGLEGITAFLEKRPPSYTR

Sequences:

>Translated_263_residues
MSAELLASRPVDSASTLVLTLSNPGARNALHPDIYAAGIEAMNAAERDASIGAVVLTGADRFFCAGGNLNRLLENRAKAP
AVQAASIDLLGEWITAIRAMSKPVIAAVEGAAAGAGFSLALACDLIVAADDAKFVMSYARVGLTPDGGGSWFLARALPRA
LATELLIEGKQTSAKRLHDLGVVNRLARPGSALGDALAWADELGGVSPNAIARVKALLAQAPDHSLATHLAAERDHFVAS
LHHPDGLEGITAFLEKRPPSYTR
>Mature_262_residues
SAELLASRPVDSASTLVLTLSNPGARNALHPDIYAAGIEAMNAAERDASIGAVVLTGADRFFCAGGNLNRLLENRAKAPA
VQAASIDLLGEWITAIRAMSKPVIAAVEGAAAGAGFSLALACDLIVAADDAKFVMSYARVGLTPDGGGSWFLARALPRAL
ATELLIEGKQTSAKRLHDLGVVNRLARPGSALGDALAWADELGGVSPNAIARVKALLAQAPDHSLATHLAAERDHFVASL
HHPDGLEGITAFLEKRPPSYTR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=257, Percent_Identity=29.1828793774319, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI70995211, Length=259, Percent_Identity=30.8880308880309, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542718, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=29.277566539924, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI25453481, Length=251, Percent_Identity=25.4980079681275, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI51538573, Length=251, Percent_Identity=25.4980079681275, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI4757966, Length=210, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI51538581, Length=210, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI4757968, Length=255, Percent_Identity=25.0980392156863, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI49355787, Length=255, Percent_Identity=25.0980392156863, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI221136756, Length=248, Percent_Identity=24.5967741935484, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221136753, Length=248, Percent_Identity=24.5967741935484, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221307494, Length=207, Percent_Identity=26.5700483091787, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260274832, Length=215, Percent_Identity=26.9767441860465, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45643119, Length=215, Percent_Identity=26.9767441860465, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI260275230, Length=215, Percent_Identity=26.9767441860465, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI116235487, Length=208, Percent_Identity=28.3653846153846, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=35.1351351351351, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1787660, Length=247, Percent_Identity=35.6275303643725, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI221142681, Length=266, Percent_Identity=33.4586466165414, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788597, Length=246, Percent_Identity=30.0813008130081, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788682, Length=185, Percent_Identity=32.972972972973, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082183, Length=177, Percent_Identity=27.683615819209, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=250, Percent_Identity=31.2, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25145438, Length=245, Percent_Identity=31.8367346938775, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=26.2548262548263, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=245, Percent_Identity=23.6734693877551, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=245, Percent_Identity=25.7142857142857, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=221, Percent_Identity=26.2443438914027, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=28.4153005464481, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=159, Percent_Identity=30.8176100628931, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144276, Length=190, Percent_Identity=30, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=190, Percent_Identity=30, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=190, Percent_Identity=30, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=259, Percent_Identity=24.7104247104247, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=32.6530612244898, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=32.6530612244898, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653139, Length=249, Percent_Identity=31.3253012048193, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI19922422, Length=244, Percent_Identity=27.4590163934426, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654903, Length=243, Percent_Identity=22.6337448559671, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI19920382, Length=218, Percent_Identity=27.5229357798165, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357171, Length=250, Percent_Identity=24.4, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650670, Length=193, Percent_Identity=31.0880829015544, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27268; Mature: 27137

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAELLASRPVDSASTLVLTLSNPGARNALHPDIYAAGIEAMNAAERDASIGAVVLTGAD
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCC
RFFCAGGNLNRLLENRAKAPAVQAASIDLLGEWITAIRAMSKPVIAAVEGAAAGAGFSLA
EEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCHHHH
LACDLIVAADDAKFVMSYARVGLTPDGGGSWFLARALPRALATELLIEGKQTSAKRLHDL
HHHEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GVVNRLARPGSALGDALAWADELGGVSPNAIARVKALLAQAPDHSLATHLAAERDHFVAS
HHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEE
LHHPDGLEGITAFLEKRPPSYTR
CCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SAELLASRPVDSASTLVLTLSNPGARNALHPDIYAAGIEAMNAAERDASIGAVVLTGAD
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCC
RFFCAGGNLNRLLENRAKAPAVQAASIDLLGEWITAIRAMSKPVIAAVEGAAAGAGFSLA
EEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCHHHH
LACDLIVAADDAKFVMSYARVGLTPDGGGSWFLARALPRALATELLIEGKQTSAKRLHDL
HHHEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GVVNRLARPGSALGDALAWADELGGVSPNAIARVKALLAQAPDHSLATHLAAERDHFVAS
HHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEE
LHHPDGLEGITAFLEKRPPSYTR
CCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]