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The map label for this gene is aspC [H]

Identifier: 238028104

GI number: 238028104

Start: 2914126

End: 2915325

Strand: Direct

Name: aspC [H]

Synonym: bglu_1g25550

Alternate gene names: 238028104

Gene position: 2914126-2915325 (Clockwise)

Preceding gene: 238028098

Following gene: 238028105

Centisome position: 74.6

GC content: 66.67

Gene sequence:

>1200_bases
ATGTCGCTCTTCTCCGCTGTCGAACTCGCGCCCCGCGATCCGATCCTGGGCCTCAACGAAGCATTCAACGCCGATACGCG
CCCGACCAAGGTGAATCTCGGCGTCGGCGTGTACACCAACGAGGAAGGCAAGATCCCGCTGCTGCGCGCGGTGCGCGACG
CGGAAAAGGCCCGCGTCGAGGCCGGCCTGCCGCGCGGCTACTTGCCGATCGACGGTATTGCCGCCTACGACGCTGCGGTG
CAGAAGCAGGTGCTCGGCAACGACTCCCCGCTGATCGCGGCAGGCCGCGTCGTGACCGCGCAGGCAATCGGCGGCACGGG
CGCGCTGAAGATCGGCGCAGATTTCCTGCGCATGGTGAACCCCAAGGCCCGCGTGGCGATCAGCAACCCGAGCTGGGAAA
ACCACCGCGCGCTGTTCGAGATGGCCGGCTTCCCGGTCGACGTATATCCGTATTACGACGCGGCCACCAACGGCGTGAAC
TTCGACGCCATGCTCGACGCGCTGAACGGTTACGCGGCCGGCACGATCGTCGTGCTGCACGCCTGCTGCCACAACCCGAC
CGGCGTCGACCTGACGGACGCGCAATGGGGCCGCGTCGTCGAAGTGGTCAAGGCGCGCCAGCTCGTGCCGTTCCTCGACA
TGGCCTACCAGGGCTTCGGTGAAAGCCTCGAGGCCGACTCGGCCGCCGTGCGCCTGTTCGCCGCCGCCGACCTGAATGTG
TTCGTGTCGTCGTCGTTCTCGAAGTCGTTCTCGCTGTACGGCGAGCGTATTGGCGCATTGTCGATCATCACTGGCAGCAA
GGACGAGGCCACGCGCGTGCTGTCGCAGTTGAAGCGCGTGATCCGCACCAACTACTCGAACCCGCCGACGCACGGCGGGG
CGCTCGTCTCCGCGGTGCTGGCCTCGCCGGATCTGTATGCCGCATGGGTCGAGGAACTCGGCGAAATGCGCGATCGCATC
CGCGCGATGCGCAACGGCCTCGTCGAGCGCCTGAAGGCCAGCGGCGTCGACCGCGACTTCAGCTTCATCAATGCACAACG
CGGCATGTTCTCGTACTCGGGCCTGACGGCCGCGCAGGTCGATCGGCTGCGCGAAGAGTTCGGCATCTACGCCGTGAGCA
CGGGCCGCATCTGCGTGGCCGCGCTCAACACGCGCAACCTCGACGTGGTGGCGAACGCGATCGCGGCAGTGCTGAAGTAA

Upstream 100 bases:

>100_bases
CTCCGGCCGCCGCGCTGGCAGTCAGACGGCGCGGCATCCCGTCTTCGCTCCCGCGTCCGGACCCCGATTTCATTCCACTA
CTTACTGCTGCGAAATCACC

Downstream 100 bases:

>100_bases
GCGACATCGCCGCGCGGACCTCGCGCGGCGACATACCGAAGACGCGCTCCCCGGAGCGCGTTTTTTCATTCCAGCGCCGA
TGGCACGCCGACGAAAGCGT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSLFSAVELAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEEGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDAAV
QKQVLGNDSPLIAAGRVVTAQAIGGTGALKIGADFLRMVNPKARVAISNPSWENHRALFEMAGFPVDVYPYYDAATNGVN
FDAMLDALNGYAAGTIVVLHACCHNPTGVDLTDAQWGRVVEVVKARQLVPFLDMAYQGFGESLEADSAAVRLFAAADLNV
FVSSSFSKSFSLYGERIGALSIITGSKDEATRVLSQLKRVIRTNYSNPPTHGGALVSAVLASPDLYAAWVEELGEMRDRI
RAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQVDRLREEFGIYAVSTGRICVAALNTRNLDVVANAIAAVLK

Sequences:

>Translated_399_residues
MSLFSAVELAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEEGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDAAV
QKQVLGNDSPLIAAGRVVTAQAIGGTGALKIGADFLRMVNPKARVAISNPSWENHRALFEMAGFPVDVYPYYDAATNGVN
FDAMLDALNGYAAGTIVVLHACCHNPTGVDLTDAQWGRVVEVVKARQLVPFLDMAYQGFGESLEADSAAVRLFAAADLNV
FVSSSFSKSFSLYGERIGALSIITGSKDEATRVLSQLKRVIRTNYSNPPTHGGALVSAVLASPDLYAAWVEELGEMRDRI
RAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQVDRLREEFGIYAVSTGRICVAALNTRNLDVVANAIAAVLK
>Mature_398_residues
SLFSAVELAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEEGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDAAVQ
KQVLGNDSPLIAAGRVVTAQAIGGTGALKIGADFLRMVNPKARVAISNPSWENHRALFEMAGFPVDVYPYYDAATNGVNF
DAMLDALNGYAAGTIVVLHACCHNPTGVDLTDAQWGRVVEVVKARQLVPFLDMAYQGFGESLEADSAAVRLFAAADLNVF
VSSSFSKSFSLYGERIGALSIITGSKDEATRVLSQLKRVIRTNYSNPPTHGGALVSAVLASPDLYAAWVEELGEMRDRIR
AMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQVDRLREEFGIYAVSTGRICVAALNTRNLDVVANAIAAVLK

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=398, Percent_Identity=43.4673366834171, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=40.8977556109726, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI117414139, Length=399, Percent_Identity=27.3182957393484, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1790488, Length=399, Percent_Identity=52.6315789473684, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=46.969696969697, Blast_Score=387, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71981858, Length=400, Percent_Identity=41.25, Blast_Score=342, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI25147133, Length=399, Percent_Identity=41.1027568922306, Blast_Score=323, Evalue=7e-89,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=38.0597014925373, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17569537, Length=398, Percent_Identity=33.1658291457286, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=40.3755868544601, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17550384, Length=269, Percent_Identity=32.7137546468402, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323055, Length=408, Percent_Identity=36.5196078431373, Blast_Score=282, Evalue=8e-77,
Organism=Saccharomyces cerevisiae, GI6322743, Length=435, Percent_Identity=30.8045977011494, Blast_Score=226, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24580970, Length=400, Percent_Identity=41.25, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI24580972, Length=400, Percent_Identity=41.25, Blast_Score=317, Evalue=8e-87,
Organism=Drosophila melanogaster, GI19920542, Length=393, Percent_Identity=41.2213740458015, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI19922362, Length=401, Percent_Identity=39.1521197007481, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24654046, Length=401, Percent_Identity=39.1521197007481, Blast_Score=292, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42806; Mature: 42675

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVELAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEEGKIPLLRAVRDAEKARVE
CCCHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AGLPRGYLPIDGIAAYDAAVQKQVLGNDSPLIAAGRVVTAQAIGGTGALKIGADFLRMVN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCEEHHHHHHHHHCC
PKARVAISNPSWENHRALFEMAGFPVDVYPYYDAATNGVNFDAMLDALNGYAAGTIVVLH
CCCEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHH
ACCHNPTGVDLTDAQWGRVVEVVKARQLVPFLDMAYQGFGESLEADSAAVRLFAAADLNV
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCEE
FVSSSFSKSFSLYGERIGALSIITGSKDEATRVLSQLKRVIRTNYSNPPTHGGALVSAVL
EEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ASPDLYAAWVEELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEECCCCHHHHH
DRLREEFGIYAVSTGRICVAALNTRNLDVVANAIAAVLK
HHHHHHHCEEEEECCCEEEEEECCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SLFSAVELAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEEGKIPLLRAVRDAEKARVE
CCHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AGLPRGYLPIDGIAAYDAAVQKQVLGNDSPLIAAGRVVTAQAIGGTGALKIGADFLRMVN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCEEHHHHHHHHHCC
PKARVAISNPSWENHRALFEMAGFPVDVYPYYDAATNGVNFDAMLDALNGYAAGTIVVLH
CCCEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHH
ACCHNPTGVDLTDAQWGRVVEVVKARQLVPFLDMAYQGFGESLEADSAAVRLFAAADLNV
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCEE
FVSSSFSKSFSLYGERIGALSIITGSKDEATRVLSQLKRVIRTNYSNPPTHGGALVSAVL
EEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ASPDLYAAWVEELGEMRDRIRAMRNGLVERLKASGVDRDFSFINAQRGMFSYSGLTAAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEECCCCHHHHH
DRLREEFGIYAVSTGRICVAALNTRNLDVVANAIAAVLK
HHHHHHHCEEEEECCCEEEEEECCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]