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The map label for this gene is argA [H]

Identifier: 238028056

GI number: 238028056

Start: 2851725

End: 2853092

Strand: Direct

Name: argA [H]

Synonym: bglu_1g25070

Alternate gene names: 238028056

Gene position: 2851725-2853092 (Clockwise)

Preceding gene: 238028050

Following gene: 238028057

Centisome position: 73.0

GC content: 68.13

Gene sequence:

>1368_bases
ATGAATTCCCAAACCGACCTCCCCGCCGCGCCGACGCCGCCGGCCGTCGACGCGACCGCCATCAGCCACGCCCAGTTCGT
CGACTGGATGCGCTCCGTCGCGCCCTATATTCACAAGTTCCGCAACAGCACGTTCGTCATCGGCTTCGGCGGCGAGGTGG
TGCAGCAGGGCCTGCTGAACGCGCTCGTCGCCGACATCGCGCTGCTGCAGGCGATGGGCATCCAGATCGTGCTGGTGCAC
GGCTCGCGCCCGCAGCTCGAGGAGCAGTTGAACCTGCACGGCGTGCAGTCCGAGTTCTCGCACGGGCTGCGCGTGACCGA
CGCGCGCGCGCTCGAATCGTCGAAGGAAGCGGCCGGCGAAGTGCGCCTGGACATCGAGGCGGCGGTCAGCCAGGGCCTGC
CGAATTCGCCGATGGCGCACGCGCACATCAGCGTGGTCTCGGGCAACTTCGTGACGGCGAGACCGGTCGGTATCCTCGAC
GGCGTCGATTTCCAGCACACCGGCGTGGTGCGCAAGATCGATGCCGAATCGATCCGCCATTCGCTGGCGAGCCGCAAGCT
CGTGCTGCTCTCGCCGCTCGGCTTCTCGCCCACGGGCGAGGCGTTCAACCTGTCGATGGAGGATGTCGCCTCGGCGGCCG
CGATCGCGCTGCGCGCCGACAAGCTGATCTTCCTGACCGACGCGCCGGGCCTCGTCGACGAGGAGGGCGAGCTGATCGGT
GAAATGTCGCTCGACGCGGCCGCCGAGCTGCTCGACTCCGGCAACCTGCAGGACGACGAGGCGTTCTACCTGAAGCATGC
GATCCGCGGCTGCCGCGGCGGCGTGGCGCGGGGGCATCTGGTGCCCTACTCGCTCGACGGCGGCGTGCTGCTGGAACTGT
TCCTGCACGACGGCGTCGGCACCATGATCTCCTACGAGAATCTGGAAAGCCTGCGCGAAGCCACGCCGGACGACGTCGGC
GGCATCCTCACGCTGATCGAGCCGCTCGAGAGCGACGGCACGCTGGTGCGGCGCGGCCGCCACCAGATCGAGCGCGACAT
CGACCACTTCTCGGTGATCGAGCACGATGGCGTGCTGTTCGGCTGCGCGGCGCTGTACCCCTATACGCAGGAGAAGATCG
GCGAGATGGCCTGCCTGACCGTCGCGCCCGAGGCGCAGGGTTCCGGCGACGGCGAGCGCCTGCTCAAGCGCATCGAGCAG
CGCGCCCGCGCGCGCGGCCTCAAGCGCATCTTCGTGCTGACGACCCGCACCGAGCACTGGTTCCTCAAGCGCGGCTTCGT
CAAGGTCAGCGTCGACGACCTGCCCGAGGACCGCCGCAAACTCTATAACTGGCAGCGCAAGTCGCTCGTGCTGATGAAGC
AGCTCTGA

Upstream 100 bases:

>100_bases
CGGGCCGACGGCTGCGCGCCTCGATCGGCCGGTGCATCCGCGCGCTTCGGTGCGGAGCTTTTGGGTACATTCGACATGGG
GGCGCATTATAATCCCGCCC

Downstream 100 bases:

>100_bases
GCGGCGCGACGCGCGCCCCCTCCCCAATCGATTACAGGAGAAGTCCACGATGTCCCGTATGGTTCAATGCGCAAAGCTCG
GCCACGAAGCCGAGGGCCTC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNSQTDLPAAPTPPAVDATAISHAQFVDWMRSVAPYIHKFRNSTFVIGFGGEVVQQGLLNALVADIALLQAMGIQIVLVH
GSRPQLEEQLNLHGVQSEFSHGLRVTDARALESSKEAAGEVRLDIEAAVSQGLPNSPMAHAHISVVSGNFVTARPVGILD
GVDFQHTGVVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKLIFLTDAPGLVDEEGELIG
EMSLDAAAELLDSGNLQDDEAFYLKHAIRGCRGGVARGHLVPYSLDGGVLLELFLHDGVGTMISYENLESLREATPDDVG
GILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYTQEKIGEMACLTVAPEAQGSGDGERLLKRIEQ
RARARGLKRIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL

Sequences:

>Translated_455_residues
MNSQTDLPAAPTPPAVDATAISHAQFVDWMRSVAPYIHKFRNSTFVIGFGGEVVQQGLLNALVADIALLQAMGIQIVLVH
GSRPQLEEQLNLHGVQSEFSHGLRVTDARALESSKEAAGEVRLDIEAAVSQGLPNSPMAHAHISVVSGNFVTARPVGILD
GVDFQHTGVVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKLIFLTDAPGLVDEEGELIG
EMSLDAAAELLDSGNLQDDEAFYLKHAIRGCRGGVARGHLVPYSLDGGVLLELFLHDGVGTMISYENLESLREATPDDVG
GILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYTQEKIGEMACLTVAPEAQGSGDGERLLKRIEQ
RARARGLKRIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
>Mature_455_residues
MNSQTDLPAAPTPPAVDATAISHAQFVDWMRSVAPYIHKFRNSTFVIGFGGEVVQQGLLNALVADIALLQAMGIQIVLVH
GSRPQLEEQLNLHGVQSEFSHGLRVTDARALESSKEAAGEVRLDIEAAVSQGLPNSPMAHAHISVVSGNFVTARPVGILD
GVDFQHTGVVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKLIFLTDAPGLVDEEGELIG
EMSLDAAAELLDSGNLQDDEAFYLKHAIRGCRGGVARGHLVPYSLDGGVLLELFLHDGVGTMISYENLESLREATPDDVG
GILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYTQEKIGEMACLTVAPEAQGSGDGERLLKRIEQ
RARARGLKRIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=436, Percent_Identity=45.1834862385321, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6320913, Length=298, Percent_Identity=24.1610738255034, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49613; Mature: 49613

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQTDLPAAPTPPAVDATAISHAQFVDWMRSVAPYIHKFRNSTFVIGFGGEVVQQGLLN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
ALVADIALLQAMGIQIVLVHGSRPQLEEQLNLHGVQSEFSHGLRVTDARALESSKEAAGE
HHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCHHHHCCCCEEEHHHHHHHHHHCCCC
VRLDIEAAVSQGLPNSPMAHAHISVVSGNFVTARPVGILDGVDFQHTGVVRKIDAESIRH
EEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCEECCCCCCCCCCEEECCHHHHHH
SLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKLIFLTDAPGLVDEEGELIG
HHHHCCEEEEECCCCCCCCCEEECCHHHHHHHHHHEEECCEEEEEECCCCCCCCCCHHHH
EMSLDAAAELLDSGNLQDDEAFYLKHAIRGCRGGVARGHLVPYSLDGGVLLELFLHDGVG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCHHEEHHHHHCCCC
TMISYENLESLREATPDDVGGILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLF
CEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHEEECCCEEE
GCAALYPYTQEKIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLKRIFVLTTRTEHW
EHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCHHH
FLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
HHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSQTDLPAAPTPPAVDATAISHAQFVDWMRSVAPYIHKFRNSTFVIGFGGEVVQQGLLN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
ALVADIALLQAMGIQIVLVHGSRPQLEEQLNLHGVQSEFSHGLRVTDARALESSKEAAGE
HHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCHHHHCCCCEEEHHHHHHHHHHCCCC
VRLDIEAAVSQGLPNSPMAHAHISVVSGNFVTARPVGILDGVDFQHTGVVRKIDAESIRH
EEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCEECCCCCCCCCCEEECCHHHHHH
SLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKLIFLTDAPGLVDEEGELIG
HHHHCCEEEEECCCCCCCCCEEECCHHHHHHHHHHEEECCEEEEEECCCCCCCCCCHHHH
EMSLDAAAELLDSGNLQDDEAFYLKHAIRGCRGGVARGHLVPYSLDGGVLLELFLHDGVG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCHHEEHHHHHCCCC
TMISYENLESLREATPDDVGGILTLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLF
CEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHEEECCCEEE
GCAALYPYTQEKIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLKRIFVLTTRTEHW
EHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCHHH
FLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
HHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]