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The map label for this gene is ispD [H]

Identifier: 238026957

GI number: 238026957

Start: 1461170

End: 1461880

Strand: Direct

Name: ispD [H]

Synonym: bglu_1g13330

Alternate gene names: 238026957

Gene position: 1461170-1461880 (Clockwise)

Preceding gene: 238026953

Following gene: 238026958

Centisome position: 37.4

GC content: 71.45

Gene sequence:

>711_bases
GTGACTCCCCGACTCTTTGCCCTGATTCCCTGCGCCGGCACCGGCTCCCGCTCCGGCTCGGCCCTGCCCAAGCAGTACCG
CACGCTGGCCGGACGCGCGCTGCTGCATTACACGCTTGCCGCGTTCGATGCGCTCAGCGAGTTCTCGCAGACGCTGGTGG
TGATCTCGCCCGACGATACGCACTTCGACGCGCGGCGCTTCGCCGGCCTGCGCTTCGCGATCAGCCGTTGCGGCGGCGCC
TCGCGCCAGGCGTCGGTATACAACGGCCTGCTGGAGCTGGCCGGGTTCGGCGCGACCGACGGCGACTGGGTGCTGGTGCA
CGACGCGGCGCGCCCCGGCATCACGCCGGCGCTGATCCGCACGCTGATCGCGACCCTCAAGGACGATCCGGTGGGCGGCA
TCGTCGCGCTGCCGGTGGCCGACACGCTCAAGCGCGTGCCGGCGGGCGGCGACGAGATCGCCCGCACCGAAGCGCGCGAC
GGCCTCTGGCAGGCCCAGACGCCGCAGATGTTCCGGATCGGCATGCTGCGCGAGGCGATCCTCGCCGCCCAGCGCGACGG
CCACGACCTGACCGACGAGGCCAGCGCGATCGAGTGGGCCGGCCACGCGCCGCGCGTGGTGCAGGGCAATCTGCGCAATT
TCAAGGTCACCTATCCCGAGGATTTCGAACTGGCCGAGGCATTCCTGTCGCGGCCCGCGAACGCCTCCTGA

Upstream 100 bases:

>100_bases
CAAGCGCCGTGTACGGCGGCGAGCGGCACGGCGGCCGAGGCGAAAGACCTATTATAAAATCCGTCTCTCGATTTCCCTAT
TTCTCCGGCGTGCCGCTCCC

Downstream 100 bases:

>100_bases
ACCCCCTTCACCACGAACCAGGCACCGCATGGACATCAGAATCGGACAAGGCTATGACGTACACCAGCTGGTTCCCGGCC
GGCCGCTCATCATCGGCGGC

Product: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Products: NA

Alternate protein names: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTPRLFALIPCAGTGSRSGSALPKQYRTLAGRALLHYTLAAFDALSEFSQTLVVISPDDTHFDARRFAGLRFAISRCGGA
SRQASVYNGLLELAGFGATDGDWVLVHDAARPGITPALIRTLIATLKDDPVGGIVALPVADTLKRVPAGGDEIARTEARD
GLWQAQTPQMFRIGMLREAILAAQRDGHDLTDEASAIEWAGHAPRVVQGNLRNFKVTYPEDFELAEAFLSRPANAS

Sequences:

>Translated_236_residues
MTPRLFALIPCAGTGSRSGSALPKQYRTLAGRALLHYTLAAFDALSEFSQTLVVISPDDTHFDARRFAGLRFAISRCGGA
SRQASVYNGLLELAGFGATDGDWVLVHDAARPGITPALIRTLIATLKDDPVGGIVALPVADTLKRVPAGGDEIARTEARD
GLWQAQTPQMFRIGMLREAILAAQRDGHDLTDEASAIEWAGHAPRVVQGNLRNFKVTYPEDFELAEAFLSRPANAS
>Mature_235_residues
TPRLFALIPCAGTGSRSGSALPKQYRTLAGRALLHYTLAAFDALSEFSQTLVVISPDDTHFDARRFAGLRFAISRCGGAS
RQASVYNGLLELAGFGATDGDWVLVHDAARPGITPALIRTLIATLKDDPVGGIVALPVADTLKRVPAGGDEIARTEARDG
LWQAQTPQMFRIGMLREAILAAQRDGHDLTDEASAIEWAGHAPRVVQGNLRNFKVTYPEDFELAEAFLSRPANAS

Specific function: Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) [H]

COG id: COG1211

COG function: function code I; 4-diphosphocytidyl-2-methyl-D-erithritol synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispD family [H]

Homologues:

Organism=Homo sapiens, GI157412259, Length=241, Percent_Identity=24.4813278008299, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789104, Length=227, Percent_Identity=39.2070484581498, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001228
- InterPro:   IPR018294 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.60 [H]

Molecular weight: Translated: 25342; Mature: 25211

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01295 ISPD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRLFALIPCAGTGSRSGSALPKQYRTLAGRALLHYTLAAFDALSEFSQTLVVISPDDT
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCC
HFDARRFAGLRFAISRCGGASRQASVYNGLLELAGFGATDGDWVLVHDAARPGITPALIR
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHH
TLIATLKDDPVGGIVALPVADTLKRVPAGGDEIARTEARDGLWQAQTPQMFRIGMLREAI
HHHHHHCCCCCCCEEEECHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LAAQRDGHDLTDEASAIEWAGHAPRVVQGNLRNFKVTYPEDFELAEAFLSRPANAS
HHHHCCCCCCCCCHHHHHHCCCCCCEEECCCCEEEEECCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPRLFALIPCAGTGSRSGSALPKQYRTLAGRALLHYTLAAFDALSEFSQTLVVISPDDT
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCC
HFDARRFAGLRFAISRCGGASRQASVYNGLLELAGFGATDGDWVLVHDAARPGITPALIR
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHH
TLIATLKDDPVGGIVALPVADTLKRVPAGGDEIARTEARDGLWQAQTPQMFRIGMLREAI
HHHHHHCCCCCCCEEEECHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LAAQRDGHDLTDEASAIEWAGHAPRVVQGNLRNFKVTYPEDFELAEAFLSRPANAS
HHHHCCCCCCCCCHHHHHHCCCCCCEEECCCCEEEEECCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA