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The map label for this gene is atzB [H]

Identifier: 238026946

GI number: 238026946

Start: 1444907

End: 1446223

Strand: Direct

Name: atzB [H]

Synonym: bglu_1g13210

Alternate gene names: 238026946

Gene position: 1444907-1446223 (Clockwise)

Preceding gene: 238026943

Following gene: 238026953

Centisome position: 36.99

GC content: 71.98

Gene sequence:

>1317_bases
ATGGATGCGCAGCGCCGCGAATTGCGCGACGCGGGCCTCTTCATCGAGGACAACCGGATCATCGCGGTCGGCCCGAGCGA
TACGCTGCCCGACACGGCCGACGAGGTCCTCGACCTGCGCGGCCACCTGCTGCTGCCGGGCCTCGTGAACACGCATCACC
ACATGTATCAGAGCCTCACGCGCGCGGTGCCGGCTGCCCAGAACGCGGAGCTGTTCGACTGGCTCACCGGCCTGTACCGG
ATCTGGCAGCATCTGACGCCCGAGATGGTCGAGGTGTCGACGCTGACCGCGATGGCCGAGCTGCTGCTGTCGGGCTGCAC
CACCTCGAGCGACCATCTCTACCTCTATCCGAACGGCGTGCGGCTCGATCACAGCATCGAGGCCGCGCGCCGGATCGGCA
TGCGTTTCCATGCGAGCCGCAGCAGCATGAGCGTGGGGCAGCGCGACGGCGGCCTGCCGCCCGATTCGCTGGTCGAGCGC
GAGGCCGCGATTCTCGACGATACCCAGCGGCTGATCGAGACCTACCACGATGCCGGGCGCTACGCGATGCTGCGGGTGGC
GGTCGCCCCCTGTTCACCGTTCTCGGTGAGCCGCGAGCTGATGCGCGAATCGGCGCGGCTCGCGCGTGCTCACGGCGTCT
CGCTGCACACCCACCTGGCCGAGAACGCGCGCGACGTGGCCTACAGCCGCGAGCGCTTCGGCATGACGCCGGCGCAGTAT
GCGGAGGATCTCGGCTGGGTCGGCCCCGACGTCTGGCACGCGCACTGCGTGCAGCTCGACGACGCCGGCATCGCGTTGTT
CGCCCGCACCGGCACCGGCGTCGCGCATTGCCCGTGCTCGAACATGCGGCTCGCCTCGGGAATCGCGCCGGTTCGGCGCA
TGCGGCTCGCGGGCGTGCCGGTGGGGCTCGGCGTGGACGGCTCGGCCTCCAACGACGGCGCGCAGATGGTGGCCGAGGCG
CGCCAGGCCTTGCTGTTGCAGCGGGTCGGCTTCGGGCCCGATGCGATGACGGCGCGCGAGGCGCTCGAGATCGCGACGCT
GGGCGGCGCCCGGGTGCTGAACCGCGACGACATCGGCGCGCTCGCGCCCGGCATGGCCGCCGACTTCGTCGCGTTCGACC
TGGCCCAGCCCGGCTTCGCCGGCGCGCTGCACGATCCGGTCGCGGCGCTGGTGTTCTGCGCGCCCTCACAGGTGGCGTGG
AGCGTCGTAAACGGCCGCGTGGTGGTGCGCCAGGGGCGGCTCGCGAGCCTCGATCCCGCGCCGCTCGTCGCGCGCCACAA
CGCGCTCGCGCGCCAGCTGGTCGAGGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
ATCGAATCCGCGCCACGGCGCGTCCGCCTTTGCCCTTTCGACCGGCCCTGCCGCGCGCGGCCGCACCCTGCTGGTGCGTC
ACGCCGAGGTGCTGGTCACG

Downstream 100 bases:

>100_bases
CCGCGGCCGCCGCGACGAGGCTCAGGGATCGATCAGGGTGCGGGTGGCCTCGGCCACCAGGCTGCGCAGCCAGCGCACCT
CGTCCGAGTAATGGCAGCGT

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MDAQRRELRDAGLFIEDNRIIAVGPSDTLPDTADEVLDLRGHLLLPGLVNTHHHMYQSLTRAVPAAQNAELFDWLTGLYR
IWQHLTPEMVEVSTLTAMAELLLSGCTTSSDHLYLYPNGVRLDHSIEAARRIGMRFHASRSSMSVGQRDGGLPPDSLVER
EAAILDDTQRLIETYHDAGRYAMLRVAVAPCSPFSVSRELMRESARLARAHGVSLHTHLAENARDVAYSRERFGMTPAQY
AEDLGWVGPDVWHAHCVQLDDAGIALFARTGTGVAHCPCSNMRLASGIAPVRRMRLAGVPVGLGVDGSASNDGAQMVAEA
RQALLLQRVGFGPDAMTAREALEIATLGGARVLNRDDIGALAPGMAADFVAFDLAQPGFAGALHDPVAALVFCAPSQVAW
SVVNGRVVVRQGRLASLDPAPLVARHNALARQLVEAAR

Sequences:

>Translated_438_residues
MDAQRRELRDAGLFIEDNRIIAVGPSDTLPDTADEVLDLRGHLLLPGLVNTHHHMYQSLTRAVPAAQNAELFDWLTGLYR
IWQHLTPEMVEVSTLTAMAELLLSGCTTSSDHLYLYPNGVRLDHSIEAARRIGMRFHASRSSMSVGQRDGGLPPDSLVER
EAAILDDTQRLIETYHDAGRYAMLRVAVAPCSPFSVSRELMRESARLARAHGVSLHTHLAENARDVAYSRERFGMTPAQY
AEDLGWVGPDVWHAHCVQLDDAGIALFARTGTGVAHCPCSNMRLASGIAPVRRMRLAGVPVGLGVDGSASNDGAQMVAEA
RQALLLQRVGFGPDAMTAREALEIATLGGARVLNRDDIGALAPGMAADFVAFDLAQPGFAGALHDPVAALVFCAPSQVAW
SVVNGRVVVRQGRLASLDPAPLVARHNALARQLVEAAR
>Mature_438_residues
MDAQRRELRDAGLFIEDNRIIAVGPSDTLPDTADEVLDLRGHLLLPGLVNTHHHMYQSLTRAVPAAQNAELFDWLTGLYR
IWQHLTPEMVEVSTLTAMAELLLSGCTTSSDHLYLYPNGVRLDHSIEAARRIGMRFHASRSSMSVGQRDGGLPPDSLVER
EAAILDDTQRLIETYHDAGRYAMLRVAVAPCSPFSVSRELMRESARLARAHGVSLHTHLAENARDVAYSRERFGMTPAQY
AEDLGWVGPDVWHAHCVQLDDAGIALFARTGTGVAHCPCSNMRLASGIAPVRRMRLAGVPVGLGVDGSASNDGAQMVAEA
RQALLLQRVGFGPDAMTAREALEIATLGGARVLNRDDIGALAPGMAADFVAFDLAQPGFAGALHDPVAALVFCAPSQVAW
SVVNGRVVVRQGRLASLDPAPLVARHNALARQLVEAAR

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=348, Percent_Identity=23.8505747126437, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1789249, Length=388, Percent_Identity=30.4123711340206, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87082177, Length=437, Percent_Identity=24.7139588100687, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17540282, Length=404, Percent_Identity=23.2673267326733, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319963, Length=347, Percent_Identity=25.9365994236311, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24643849, Length=356, Percent_Identity=25.2808988764045, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 47268; Mature: 47268

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAQRRELRDAGLFIEDNRIIAVGPSDTLPDTADEVLDLRGHLLLPGLVNTHHHMYQSLT
CCCHHHHHHHCCCEEECCEEEEECCCCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHH
RAVPAAQNAELFDWLTGLYRIWQHLTPEMVEVSTLTAMAELLLSGCTTSSDHLYLYPNGV
HHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
RLDHSIEAARRIGMRFHASRSSMSVGQRDGGLPPDSLVEREAAILDDTQRLIETYHDAGR
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YAMLRVAVAPCSPFSVSRELMRESARLARAHGVSLHTHLAENARDVAYSRERFGMTPAQY
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
AEDLGWVGPDVWHAHCVQLDDAGIALFARTGTGVAHCPCSNMRLASGIAPVRRMRLAGVP
HHHHCCCCCHHHHHHHEEECCCCEEEEEECCCCEEECCCCCCCHHHCHHHHHHHHHCCCC
VGLGVDGSASNDGAQMVAEARQALLLQRVGFGPDAMTAREALEIATLGGARVLNRDDIGA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCCC
LAPGMAADFVAFDLAQPGFAGALHDPVAALVFCAPSQVAWSVVNGRVVVRQGRLASLDPA
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCEEEEECCCCCCCCCC
PLVARHNALARQLVEAAR
CHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDAQRRELRDAGLFIEDNRIIAVGPSDTLPDTADEVLDLRGHLLLPGLVNTHHHMYQSLT
CCCHHHHHHHCCCEEECCEEEEECCCCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHH
RAVPAAQNAELFDWLTGLYRIWQHLTPEMVEVSTLTAMAELLLSGCTTSSDHLYLYPNGV
HHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
RLDHSIEAARRIGMRFHASRSSMSVGQRDGGLPPDSLVEREAAILDDTQRLIETYHDAGR
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YAMLRVAVAPCSPFSVSRELMRESARLARAHGVSLHTHLAENARDVAYSRERFGMTPAQY
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
AEDLGWVGPDVWHAHCVQLDDAGIALFARTGTGVAHCPCSNMRLASGIAPVRRMRLAGVP
HHHHCCCCCHHHHHHHEEECCCCEEEEEECCCCEEECCCCCCCHHHCHHHHHHHHHCCCC
VGLGVDGSASNDGAQMVAEARQALLLQRVGFGPDAMTAREALEIATLGGARVLNRDDIGA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCCC
LAPGMAADFVAFDLAQPGFAGALHDPVAALVFCAPSQVAWSVVNGRVVVRQGRLASLDPA
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCEEEEECCCCCCCCCC
PLVARHNALARQLVEAAR
CHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]