Click here to switch to the map view.

The map label for this gene is ldcA [H]

Identifier: 238026936

GI number: 238026936

Start: 1431277

End: 1432218

Strand: Direct

Name: ldcA [H]

Synonym: bglu_1g13080

Alternate gene names: 238026936

Gene position: 1431277-1432218 (Clockwise)

Preceding gene: 238026935

Following gene: 238026937

Centisome position: 36.64

GC content: 69.0

Gene sequence:

>942_bases
ATGACGAATCCCTCCTCCCTGCCACGCACGATCCGTCTGCTGGCCCCCTCCGGTTACCCGCATGATCCGCTCGCGGTGCA
GCGCGCGCTCGAGCGCCTCAGCAACGCGCAGCACGTGCTGCAAAACCTGATCGCCGTCGAGCGGCGCTACCTGCGGTTCG
CCGGCACCGACGGCGAACGCGCCGCCGACCTGAACCATCTCGCCGATCCGTCGCAGCCGCTGCCCGACATCGGGCTCGCG
GTGCGCGGCGGCTACGGCGCCGTGCGCATCCTGCACGGGCTCGACTATCGCGGGCTCGAGCGCCGCCTGCGCGATCAGCC
GGTTGCGCTGTGCGGCCACAGCGATTTCACCGCGATCCAGCTCGCGCTGCTCGCGAAGTCGCGCGTGAAGACCTTCGGCG
GCCCGATGCTGTCGGCCGATTTCGGCGCCGAAACGCCGAGCGAATTCACCATGACGCAGTTCTGGACGACGCTCACGCAG
CCGTCCGCGACGATCGTGGCCGAGGTGCCGCAGCAGCAGTCGGCGGACGTGGCGGGCACGCTCTGGGGCGGCAACCTCGC
GATCCTCGCCTCGCTGGTCGGCACACCGTACATGCCGCAGATCGAGGGCGGCATCCTGTTCATCGAGGACGTCAACGAGC
AGCCGTTCCGCATCGAGCGGATGATCTATACGCTGCATTTCGCCGGCATCCTCGCGCGCCAGCAGGCGCTGGTGCTGGGC
CAGTTCACCGGCGCGCGCGCGTTCGACTACGACAACGGCTACGATCTGCAGGCCGTGATCGACCAGATGCGCGAGGTGAT
CGGCATCCCGATCATCACCGGCCTGCAGTTCGGCCATGTGCCGGACCTGCTGACGCTGCCGGTGGGCGGCCAGGCGCGGC
TCGTCGCGAACCAACACGGTTTCCGCCTGAGCGTCTCGGACTATCCGGTGCTGGGCGGCTGA

Upstream 100 bases:

>100_bases
TGCGATTCGGCCGCGCCCGGCGCCGACTGAACCAGTCGCGGTGGCGCGGCTCTAATCGGGCAATCCCAGCCGGGCCAGTC
CCTTTTTTCTCCGCGAGCCG

Downstream 100 bases:

>100_bases
GGTTCTGGCCGACGGGCGCGAAACGAGGCGGGCGACCGCCTTTTTTTTCATCCACATAAGCAACTAACGGTCTGACATCG
CGGGCCCCTCCGAATGGCTG

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTNPSSLPRTIRLLAPSGYPHDPLAVQRALERLSNAQHVLQNLIAVERRYLRFAGTDGERAADLNHLADPSQPLPDIGLA
VRGGYGAVRILHGLDYRGLERRLRDQPVALCGHSDFTAIQLALLAKSRVKTFGGPMLSADFGAETPSEFTMTQFWTTLTQ
PSATIVAEVPQQQSADVAGTLWGGNLAILASLVGTPYMPQIEGGILFIEDVNEQPFRIERMIYTLHFAGILARQQALVLG
QFTGARAFDYDNGYDLQAVIDQMREVIGIPIITGLQFGHVPDLLTLPVGGQARLVANQHGFRLSVSDYPVLGG

Sequences:

>Translated_313_residues
MTNPSSLPRTIRLLAPSGYPHDPLAVQRALERLSNAQHVLQNLIAVERRYLRFAGTDGERAADLNHLADPSQPLPDIGLA
VRGGYGAVRILHGLDYRGLERRLRDQPVALCGHSDFTAIQLALLAKSRVKTFGGPMLSADFGAETPSEFTMTQFWTTLTQ
PSATIVAEVPQQQSADVAGTLWGGNLAILASLVGTPYMPQIEGGILFIEDVNEQPFRIERMIYTLHFAGILARQQALVLG
QFTGARAFDYDNGYDLQAVIDQMREVIGIPIITGLQFGHVPDLLTLPVGGQARLVANQHGFRLSVSDYPVLGG
>Mature_312_residues
TNPSSLPRTIRLLAPSGYPHDPLAVQRALERLSNAQHVLQNLIAVERRYLRFAGTDGERAADLNHLADPSQPLPDIGLAV
RGGYGAVRILHGLDYRGLERRLRDQPVALCGHSDFTAIQLALLAKSRVKTFGGPMLSADFGAETPSEFTMTQFWTTLTQP
SATIVAEVPQQQSADVAGTLWGGNLAILASLVGTPYMPQIEGGILFIEDVNEQPFRIERMIYTLHFAGILARQQALVLGQ
FTGARAFDYDNGYDLQAVIDQMREVIGIPIITGLQFGHVPDLLTLPVGGQARLVANQHGFRLSVSDYPVLGG

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=301, Percent_Identity=49.1694352159468, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 34061; Mature: 33930

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPSSLPRTIRLLAPSGYPHDPLAVQRALERLSNAQHVLQNLIAVERRYLRFAGTDGER
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCH
AADLNHLADPSQPLPDIGLAVRGGYGAVRILHGLDYRGLERRLRDQPVALCGHSDFTAIQ
HHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHCCCHHHHHHHHCCCCEEEECCCCHHHHH
LALLAKSRVKTFGGPMLSADFGAETPSEFTMTQFWTTLTQPSATIVAEVPQQQSADVAGT
HHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEE
LWGGNLAILASLVGTPYMPQIEGGILFIEDVNEQPFRIERMIYTLHFAGILARQQALVLG
ECCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
QFTGARAFDYDNGYDLQAVIDQMREVIGIPIITGLQFGHVPDLLTLPVGGQARLVANQHG
CCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCEEEEECCCC
FRLSVSDYPVLGG
CEEECCCCCCCCC
>Mature Secondary Structure 
TNPSSLPRTIRLLAPSGYPHDPLAVQRALERLSNAQHVLQNLIAVERRYLRFAGTDGER
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCH
AADLNHLADPSQPLPDIGLAVRGGYGAVRILHGLDYRGLERRLRDQPVALCGHSDFTAIQ
HHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHCCCHHHHHHHHCCCCEEEECCCCHHHHH
LALLAKSRVKTFGGPMLSADFGAETPSEFTMTQFWTTLTQPSATIVAEVPQQQSADVAGT
HHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEE
LWGGNLAILASLVGTPYMPQIEGGILFIEDVNEQPFRIERMIYTLHFAGILARQQALVLG
ECCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
QFTGARAFDYDNGYDLQAVIDQMREVIGIPIITGLQFGHVPDLLTLPVGGQARLVANQHG
CCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCEEEEECCCC
FRLSVSDYPVLGG
CEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]